Extremely red objects in the fields of high redshift radio galaxies

We are engaged in a program of infrared imaging photometry of high redshift radio galaxies. The observations are being done using NICMOS2 and NICMOS3 arrays on the DuPont 100-inch telescope at Las Campanas Observatory. In addition, Persson and Matthews are measuring the spectral energy distributions of normal cluster galaxies in the redshift range 0 to 1. These measurements are being done with a 58 x 62 InSb array on the Palomar 5-m telescope. During the course of these observations we have imaged roughly 20 square arcminutes of sky to limiting magnitudes greater than 20 in the J, H, and K passbands (3 sigma in 3 square arcseconds). We have detected several relatively bright, extremely red, extended objects during the course of this work. Because the radio galaxy program requires Thuan-Gunn gri photometry, we are able to construct rough photometric energy distributions for many of the objects. A sample of the galaxy magnitudes within 4 arcseconds diameter is given. All the detections are real; either the objects show up at several wavelengths, or in subsets of the data. The reddest object in the table, 9ab'B' was found in a field of galaxies in a rich cluster at z = 0.4; 9ab'A' lies 8 arcseconds from it

Protein kinase activity is associated with CD63 in melanoma cells

BACKGROUND: The tetraspan protein CD63, originally described as a stage-specific melanoma antigen but also present in a number of normal cells, regulates melanoma cell growth in nude mice, motility in serum containing media, and adhesion to several extracellular matrix proteins. CD63 has been reported to associate with β1 and β2 integrins, but the mechanism of signal transduction by CD63 is not clear. This study examined whether CD63 is associated with protein kinase and can transmit signals in melanoma cells. METHODS: Immunoprecipitation and radiolabeling were used to test for association of protein kinase activity with CD63. Adhesion of cells to monoclonal antibodies immobilized to microtiter plates was used to examine the ability of CD63 to transmit signals. RESULTS: CD63 was capable of transmitting a signal in melanoma cells that required extracellular calcium. In the absence of extracellular calcium at the time of binding to the CD63 mAb, the cell was no longer responsive to stimulation by CD63. Immunoprecipitation studies demonstrated protein kinase activity associated with CD63, and phosphoamino acid analysis revealed that most of this protein kinase activity was due to serine kinase activity. CONCLUSION: The current study suggests that serine protein kinase activity associated with CD63 may play a role in signaling by CD63 in melanoma cells

Commissioning the MMT ground-layer and laser tomography adaptive optics systems

A multi-laser adaptive optics system, at the 6.5 m MMT telescope, has been undergoing commissioning in preparation for wide-field, partially corrected as well as narrow-field, diffraction limited science observations in the thermal and near infrared. After several delays due to bad weather, we have successfully closed the full high order ground-layer adaptive optics (GLAO) control loop for the first time in February 2008 using five Rayleigh laser guide stars and a single tilt star. Characterization and automated correction of static aberrations such as non-common path errors were addressed in May 2008. Calibration measurements in preparation for laser tomography adaptive optics (LTAO) operation are planned for the fall of 2008 along with the start of shared-risk GLAO science observations. We present the results of GLAO observations with the PISCES imager, a 1 - 2.5 µm camera with a field of view of 110 arc seconds. The status of the remaining GLAO commissioning work is also reviewed. Finally, we present plans for commissioning work to implement the LTAO operating mode of the system

Decoupling of Sleep-Dependent Cortical and Hippocampal Interactions in a Neurodevelopmental Model of Schizophrenia

SummaryRhythmic neural network activity patterns are defining features of sleep, but interdependencies between limbic and cortical oscillations at different frequencies and their functional roles have not been fully resolved. This is particularly important given evidence linking abnormal sleep architecture and memory consolidation in psychiatric diseases. Using EEG, local field potential (LFP), and unit recordings in rats, we show that anteroposterior propagation of neocortical slow-waves coordinates timing of hippocampal ripples and prefrontal cortical spindles during NREM sleep. This coordination is selectively disrupted in a rat neurodevelopmental model of schizophrenia: fragmented NREM sleep and impaired slow-wave propagation in the model culminate in deficient ripple-spindle coordination and disrupted spike timing, potentially as a consequence of interneuronal abnormalities reflected by reduced parvalbumin expression. These data further define the interrelationships among slow-wave, spindle, and ripple events, indicating that sleep disturbances may be associated with state-dependent decoupling of hippocampal and cortical circuits in psychiatric diseases

Making It: Institutionalizing Collaborative Innovation in Public Higher Education

[EN] This descriptive case study provides a broad overview of JMU X-Labs, an academic maker space (in other words, a teaching lab with fabrication and digital production technologies) that hosts team-taught, project-driven multidisciplinary courses. The JMU X-Labs serves the students and faculty of James Madison University[MSR-m1] , a mid-sized, public, and undergraduate-focused university in the United States. The narrative proceeds from two different but overlapping points of view: how courses at JMU X-Labs are designed and taught; and how administration of JMU X-Labs supports them. The authors refer to specific courses, pedagogical methods, and problem-solving strategies to illustrate the narrative, and they argue throughout that pedagogy and administration are indelibly intertwined in how the organization operates. Gesturing to the broad applicability and transferability of the JMU X-Labs model, the authors mark some of areas of further research that would benefit a more robust understanding of how the organization operates and grows. Finally, the authors speculate how the dynamics of this young and growing organization may answer some core and difficult questions pertaining to innovation in higher education.[MSR-m1]James Madison University (JMU) Clearlyl referenced in abstract and opening paragraph below to explain institutional context as per reviewer request. http://ocs.editorial.upv.es/index.php/HEAD/HEAD18Mccarthy, S.; Barnes, A.; Holland, KS.; Lewis, E.; Ludwig, P.; Swayne, N. (2018). Making It: Institutionalizing Collaborative Innovation in Public Higher Education. Editorial Universitat Politècnica de València. 1549-1557. https://doi.org/10.4995/HEAD18.2018.8247OCS1549155

On-sky wide field adaptive optics correction using multiple laser guide stars at the MMT

We describe results from the first astronomical adaptive optics system to use multiple laser guide stars, located at the 6.5-m MMT telescope in Arizona. Its initial operational mode, ground-layer adaptive optics (GLAO), provides uniform stellar wavefront correction within the 2 arc minute diameter laser beacon constellation, reducing the stellar image widths by as much as 53%, from 0.70 to 0.33 arc seconds at lambda = 2.14 microns. GLAO is achieved by applying a correction to the telescope's adaptive secondary mirror that is an average of wavefront measurements from five laser beacons supplemented with image motion from a faint stellar source. Optimization of the adaptive optics system in subsequent commissioning runs will further improve correction performance where it is predicted to deliver 0.1 to 0.2 arc second resolution in the near-infrared during a majority of seeing conditions.Comment: 13 pages, 1 table, 7 figures. Accepted for publication in Astrophysical Journal. Expected March 200

The Ursinus Weekly, October 14, 1976

Ursinus news in brief: Parsons admitted to Sacred Heart ; Reiner, Bozorth receive awards; Grant supports psych research; Staskiel to make TV debut • Freshmen elect officers • Nine join faculty • USGA holds carnival • Economics club meets • Ursinus and the arts • Another look at alumni • Coming campus events • WPAZ offers intern program • Harriers surging • LV, Johns Hopkins beat Karas\u27 Bears • Sixers: ready for all new NBA • Saturday\u27s gamehttps://digitalcommons.ursinus.edu/weekly/1058/thumbnail.jp

Archiving the Scientific Legacy of Dr. Alec Costin

Alec Costin is one of Australia’s foremost ecologists, internationally respected for his pioneering work into the soils, hydrology and vegetation of the Australian alpine regions. Advisor to governments and their agencies, he was instrumental in the conservation of the Australian Alps. Alec’s field notes, data sheets and Kodachrome slides, a record of the Alps in the 1950s and 60s, are important historically and provide an important resource to interpret change in vegetation and landscapes in the Australian Alps. The University of Melbourne, funded by the Australian Alps National Parks, will catalogue and archive these materials, so future generations of scientists and historians can easily gain access to them

Comparison of bit error rate estimation methods for QPSK CO-OFDM transmission

In this letter, we experimentally study the statistical properties of a received QPSK modulated signal and compare various bit error rate (BER) estimation methods for coherent optical orthogonal frequency division multiplexing transmission. We show that the statistical BER estimation method based on the probability density function of the received QPSK symbols offers the most accurate estimate of the system performance