6,338 research outputs found

    Repaglinide (NovoNorm) in the management of Type 2 Diabetes

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    Partial Evaluation for Java Malware Detection

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    The fact that Java is platform independent gives hackers the opportunity to write exploits that can target users on any platform, which has a JVM implementation. Metasploit is a well-known source of Java exploits and to circumvent detection by Anti Virus (AV) software, obfuscation techniques are routinely applied to make an exploit more difficult to recognise. Popular obfuscation techniques for Java include string obfuscation and applying reflection to hide method calls; two techniques that can either be used together or independently. This paper shows how to apply partial evaluation to remove these obfuscations and thereby improve AV matching. The paper presents a partial evaluator for Jimple, which is a typed three-address code suitable for optimisation and program analysis, and also demonstrates how the residual Jimple code, when transformed back into Java, improves the detection rates of a number of commercial AV products

    Critical Excitation Spectrum of Quantum Chain With A Local 3-Spin Coupling

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    This article reports a measurement of the low-energy excitation spectrum along the critical line for a quantum spin chain having a local interaction between three Ising spins and longitudinal and transverse magnetic fields. The measured excitation spectrum agrees with that predicted by the (D4_4, A4_4) conformal minimal model under a nontrivial correspondence between translations at the critical line and discrete lattice translations. Under this correspondence, the measurements confirm a prediction that the critical line of this quantum spin chain and the critical point of the 2D 3-state Potts model are in the same universality class.Comment: 7 pages, 2 figure

    Excitation Spectrum at the Yang-Lee Edge Singularity of 2D Ising Model on the Strip

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    At the Yang-Lee edge singularity, finite-size scaling behavior is used to measure the low-lying excitation spectrum of the Ising quantum spin chain for free boundary conditions. The measured spectrum is used to identify the CFT that describes the Yang-Lee edge singularity of the 2D Ising model for free boundary conditions.Comment: 7 pages, 1 figur

    Linguistic Indicators of Severity and Progress in Online Text-based Therapy for Depression

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    Mental illnesses such as depression andanxiety are highly prevalent, and therapyis increasingly being offered online. Thisnew setting is a departure from face-to-face therapy, and offers both a challengeand an opportunity ā€“ it is not yet knownwhat features or approaches are likely tolead to successful outcomes in such a dif-ferent medium, but online text-based ther-apy provides large amounts of data for lin-guistic analysis. We present an initial in-vestigation into the application of compu-tational linguistic techniques, such as topicand sentiment modelling, to online ther-apy for depression and anxiety. We findthat important measures such as symptomseverity can be predicted with compara-ble accuracy to face-to-face data, usinggeneral features such as discussion topicand sentiment; however, measures of pa-tient progress are captured only by finer-grained lexical features, suggesting thataspects of style or dialogue structure mayalso be important

    The relaxation of OH (v = 1) and OD (v = 1) by H2O and D2O at temperatures from 251 to 390 K

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    We report rate coefficients for the relaxation of OH(v = 1) and OD(v = 1) by H2O and D2O as a function of temperature between 251 and 390 K. All four rate coefficients exhibit a negative dependence on temperature. In Arrhenius form, the rate coefficients for relaxation (in units of 10ā€“12 cm3 moleculeā€“1 sā€“1) can be expressed as: for OH(v = 1) + H2O between 263 and 390 K: k = (2.4 Ā± 0.9) exp((460 Ā± 115)/T); for OH(v = 1) + D2O between 256 and 371 K: k = (0.49 Ā± 0.16) exp((610 Ā± 90)/T); for OD(v = 1) + H2O between 251 and 371 K: k = (0.92 Ā± 0.16) exp((485 Ā± 48)/T); for OD(v = 1) + D2O between 253 and 366 K: k = (2.57 Ā± 0.09) exp((342 Ā± 10)/T). Rate coefficients at (297 Ā± 1 K) are also reported for the relaxation of OH(v = 2) by D2O and the relaxation of OD(v = 2) by H2O and D2O. The results are discussed in terms of a mechanism involving the formation of hydrogen-bonded complexes in which intramolecular vibrational energy redistribution can occur at rates competitive with re-dissociation to the initial collision partners in their original vibrational states. New ab initio calculations on the H2Oā€“HO system have been performed which, inter alia, yield vibrational frequencies for all four complexes: H2Oā€“HO, D2Oā€“HO, H2Oā€“DO and D2Oā€“DO. These data are then employed, adapting a formalism due to Troe (J. Troe, J. Chem. Phys., 1977, 66, 4758), in order to estimate the rates of intramolecular energy transfer from the OH (OD) vibration to other modes in the complexes in order to explain the measured relaxation ratesā€”assuming that relaxation proceeds via the hydrogen-bonded complexes

    Management Entrenchment in the Market for Corporate Control

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    Ken C.Yook, Ph.D., is associate professor of finance. Department of Finance, The Johns Hopkins University, Washington, DC 20036. George M. McCabe, Ph.D., is professor of finance, Department of Finance, University of Nebraska-Lincoln, Lincoln, NE 68588

    Investigating Topic Modelling for Therapy Dialogue Analysis

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    Previous research shows that aspects of doctor-patient communication in therapy can predict patient symptoms, satisfaction and future adherence to treatment (a significant problem with conditions such as schizophrenia). However, automatic prediction has so far shown success only when based on low-level lexical features, and it is unclear how well these can generalise to new data, or whether their effectiveness is due to their capturing aspects of style, structure or content. Here, we examine the use of topic as a higher-level measure of content, more likely to generalise and to have more explanatory power. Investigations show that while topics predict some important factors such as patient satisfaction and ratings of therapy quality, they lack the full predictive power of lower-level features. For some factors, unsupervised methods produce models comparable to manual annotation.

    Chemical ionization tandem mass spectrometer for the in situ measurement of methyl hydrogen peroxide

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    A new approach for measuring gas-phase methyl hydrogen peroxide [(MHP) CH_3OOH] utilizing chemical ionization mass spectrometry is presented. Tandem mass spectrometry is used to avoid mass interferences that hindered previous attempts to measure atmospheric CH_3OOH with CF_3Oāˆ’ clustering chemistry. CH_3OOH has been successfully measured in situ using this technique during both airborne and ground-based campaigns. The accuracy and precision for the MHP measurement are a function of water vapor mixing ratio. Typical precision at 500 pptv MHP and 100 ppmv H_2O is Ā±80 pptv (2 sigma) for a 1 s integration period. The accuracy at 100 ppmv H_2O is estimated to be better than Ā±40%. Chemical ionization tandem mass spectrometry shows considerable promise for the determination of in situ atmospheric trace gas mixing ratios where isobaric compounds or mass interferences impede accurate measurements
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