Alizay, Igoville – Le Fort (tranche 3 nord)

La poursuite des fouilles sur les communes d’Alizay et Igoville a permis d’étudier, sur cette portion de la Seine, les dynamiques de comblement de la vallée et le rythme des occupations humaines sur un peu moins de 5 ha. Ces résultats viennent compléter les travaux présentés dans le cadre du Bilan scientifique 2011 (2013, p. 19-21). Cette année, les fouilles ont principalement porté sur la lecture des dynamiques sédimentaires et des restitutions paléoenvironnementales afférentes dans un secte..

Native rodent species are unlikely sources of infection for Leishmania (Viannia) braziliensis along the Transoceanic Highway in Madre de Dios, Peru.

An estimated 2.3 million disability-adjusted life years are lost globally from leishmaniasis. In Peru's Amazon region, the department of Madre de Dios (MDD) rises above the rest of the country in terms of the annual incidence rates of human leishmaniasis. Leishmania (Viannia) braziliensis is the species most frequently responsible for the form of disease that results in tissue destruction of the nose and mouth. However, essentially nothing is known regarding the reservoirs of this vector-borne, zoonotic parasite in MDD. Wild rodents have been suspected, or proven, to be reservoirs of several Leishmania spp. in various ecosystems and countries. Additionally, people who live or work in forested terrain, especially those who are not regionally local and whose immune systems are thus naïve to the parasite, are at most risk for contracting L. (V.) braziliensis. Hence, the objective of this study was to collect tissues from wild rodents captured at several study sites along the Amazonian segment of the newly constructed Transoceanic Highway and to use molecular laboratory techniques to analyze samples for the presence of Leishmania parasites. Liver tissues were tested via polymerase chain reaction from a total of 217 rodents; bone marrow and skin biopsies (ear and tail) were also tested from a subset of these same animals. The most numerous rodent species captured and tested were Oligoryzomys microtis (40.7%), Hylaeamys perenensis (15.7%), and Proechimys spp. (12%). All samples were negative for Leishmania, implying that although incidental infections may occur, these abundant rodent species are unlikely to serve as primary reservoirs of L. (V.) braziliensis along the Transoceanic Highway in MDD. Therefore, although these rodent species may persist and even thrive in moderately altered landscapes, we did not find any evidence to suggest they pose a risk for L. (V.) braziliensis transmission to human inhabitants in this highly prevalent region

Numerical Simulation of Brazing Aluminium Alloys with Al–Si Alloys

Joining parts using low-melting temperature alloys has long been used for manufacturing complex components such as heat exchangers made of aluminium alloys. Investigations of the process have shown that core/ clad interaction during heating and brazing can lead to a significant decrease in the amount of liquid available for joint formation. This study presents a transient one-dimensional model for the process that takes into account the diffusion of silicon and the movement of the core/clad interface, with the model equations being implemented in the finite element software COMSOL Multiphysics; the results are compared to literature experimental data. Silicon profiles in the core are well described, while there appears a significant difference between predicted and experimental values of remaining clads which suggest a strong effect of silicon diffusion and liquid penetration at core grain boundaries

Reading and spelling impairments in children and adolescents with infantile myotonic dystrophy

Abstract This study investigated reading and spelling difficulties in subjects with the juvenile form of myotonic dystrophy (MD). Twenty-three consecutive patients with juvenile MD who were referred to a special clinic were assessed for reading and spelling skills (phonological processing, word identification, narrative comprehension (two tasks), information seeking in a document (TV schedule), and spelling). Reading impairments were frequent (63-84% of the subjects being below the level of literacy depending on the tasks), even in subjects without mental retardation (22-66%) despite normal word identification scores. All but two subjects had spelling difficulties. The severity of these learning difficulties was correlated with longer mutation size and maternal transmission, but could not be related to phonological deficit, suggesting that other brain dysfunction might be involved (e.g., attention, working memory, naming speed, executive function). Children with the juvenile form of MD should systematically be assessed for reading and spelling problems, and correlations with basic cognitive functioning explored.

Cleavage modification did not alter blastomere fates during bryozoan evolution

This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The study was funded by the core budget of the Sars Centre and by The European Research Council Community’s Framework Program Horizon 2020 (2014–2020) ERC grant agreement 648861 to A

Gastrointestinal motility and its enteric actors in mechanosensitivity: past and present.

International audienceCoordinated contractions of the smooth muscle layers of the gastrointestinal (GI) tract are required to produce motor patterns that ensure normal GI motility. The crucial role of the enteric nervous system (ENS), the intrinsic ganglionated network located within the GI wall, has long been recognized in the generation of the main motor patterns. However, devising an appropriate motility requires the integration of informations emanating from the lumen of the GI tract. As already found more than half a century ago, the ability of the GI tract to respond to mechanical forces such as stretch is not restricted to neuronal mechanisms. Instead, mechanosensitivity is now recognized as a property of several non-neuronal cell types, the excitability of which is probably involved in shaping the motor patterns. This brief review gives an overview on how mechanosensitivity of different cell types in the GI tract has been established and, whenever available, on what ionic conductances are involved in mechanotransduction and their potential impact on normal GI motility

Modulation de la transmission synaptique au niveau du plexus coeliaque par les afferences gastro-intestinales. Role du plexus coeliaque dans l'organisation d'un reflexe gastro-duodenal inhibiteur

SIGLEAvailable from INIST (FR), Document Supply Service, under shelf-number : TD 81460 / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Nouvelles variations sur les théorèmes d'Abel et de Lie

PARIS-BIUSJ-Thèses (751052125) / SudocCentre Technique Livre Ens. Sup. (774682301) / SudocPARIS-BIUSJ-Mathématiques rech (751052111) / SudocSudocFranceF

Apports nouveaux sur l’origine du rempart de Yainville (Seine-Maritime)

La commune de Yainville est implantée au nord de la boucle de Jumièges, vaste méandre de la Seine. Un rempart ferme cette formation d’est en ouest sur une longueur de 2,4 km. Cette structure de barrage est connue sous le nom de « Fossé Saint-Philibert ». Un diagnostic archéologique réalisé sur l’emprise d’un futur lotissement a permis de sonder l’élévation de terre et d’appréhender une partie encore non explorée de la rupture de pente, dont l’amorce constitue le lieu d’implantation du rempart. Des informations inédites apportent un nouveau regard sur l’origine de ce site et son organisation.The commune of Yainville is located in the northern section of the Jumièges loop, a large meander of the river Seine. A rampart measuring 2.4 km closes off this formation from east to west. This barrage structure is known as the Fossé Saint-Philibert (Saint Philibert Fosse). An archaeological survey performed on the area of a future development site made it possible to examine the raised ground and to achieve a comprehensive view of an unexplored part of the break in the slope, the beginning of which marks the location of the rampart. New information has shed new light on the origin of this site and its layout