Knowledge, experience, and potential risks of dating violence among Japanese university students: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>The Domestic Violence Prevention Act came into effect in Japan in 2001, but covers only marriage partner violence and post-divorce partner violence, and does not recognize intimate partner violence (IPV). The present study was performed to determine the experience of harassment, both toward and from an intimate partner, and recognition of harassment as IPV among Japanese university students.</p> <p>Methods</p> <p>A self-administered questionnaire survey regarding the experience of harassment involving an intimate partner was conducted as a cross-sectional study among freshman students in a prefectural capital city in Japan.</p> <p>Results</p> <p>A total of 274 students participated in the present study. About half of the subjects (both male and female students) had experience of at least one episode of harassment toward or had been the recipient of harassment from an intimate partner. However, the study participants did not recognize verbal harassment, controlling activities of an intimate partner, and unprotected sexual intercourse as violence. Experience of attending a lecture/seminar about domestic violence and dating violence did not contribute to appropriate help-seeking behavior.</p> <p>Conclusions</p> <p>An educational program regarding harassment and violence prevention and appropriate help-seeking behavior should be provided in early adolescence to avoid IPV among youth.</p

Analise comparativa do desempenho de ferramentas no torneamento do aluminio 2024

The aluminium alloys are used in many fields because of their versatility combined with the excellent aluminium’s properties, mentioned in the study. This study aims to compare the performance of polished Hard Metal, Hard Metal covered with TiB2 and High Speed Steel (HSS) tools, at the aluminium 2024 alloy’s turning, as a function of variation of some turning parameters such as: feed, depth of cut and cutting speed; and study the surface finish and the required power during turning by processing the output data, like analyze the chip’s features for each used tool. The results provide information of the tool’s material effects, when submitted to different turning conditions, about the output variable in question. In this way, it was possible to notice that although the Hard Metal covered with TiB2 tool has provided the better surface finish, the chip’s features were better when the turning was accomplished by the Polished Hard Metal tool. In relation to the required turning’s power, the lowest consumption occurred with the High Speed Steel toolAs ligas de alumínio possuem aplicações nos mais diversos campos devido à sua versatilidade combinada às excelentes propriedades do alumínio, mencionadas no estudo em questão. Este trabalho tem como objetivo comparar o desempenho das ferramentas de metal duro polido, metal duro recoberto com TiB2 e aço rápido, no torneamento da liga de alumínio 2024, em função da variação de alguns parâmetros de usinagem como: avanço, profundidade e velocidade de corte; e estudar o acabamento superficial e a potência requerida durante o torneamento através do tratamento dos dados de saída, bem como analisar as características dos cavacos para cada ferramenta utilizada. Os resultados fornecem informações dos efeitos do material da ferramenta, quando submetido a diferentes condições de usinagem, sobre as variáveis de saída em questão. Desta forma, foi possível perceber que embora a ferramenta de metal duro com recobrimento de TiB2 tenha apresentado o melhor acabamento superficial, as características do cavaco foram melhores quando o torneamento foi realizado com a ferramenta de metal duro polido. Em relação à potência requerida ao torneamento, o menor consumo se deu para a ferramenta de aço rápid

Resection of giant liver hemangioma in a pregnant woman with coagulopathy: Case report and literature review

Background: Hemangioma is a common benign tumor in the liver and usually asymptomatic. Scanty evidence concerning treatment modality of symptomatic hemangioma during pregnancy exists. Case: A 35 year-old woman with giant hepatic cavernous hemangioma developed consumption coagulopathy due to the enlarged tumor, and underwent danaparoid therapy from 5 weeks of gestation (GW). Magnetic resonance image revealed giant hemangioma with 20 cm in diameter in the right lobe of the liver. A surgical operation of liver resection was successfully performed at 16 GW. Thereafter, the coagulopathy disappeared. She delivered a healthy male infant at 36 GW. Conclusion: This is the first case report of surgical resection therapy for giant liver hemangioma during pregnancy

Effects of Three Types of Japanese Honey on Full-Thickness Wound in Mice

Although many previous studies reported that honey promotes wound healing, no study has examined the effects of Japanese honey. The aim of this study was to investigate the effects of three types of Japanese honey, Acacia, Buckwheat flour, and Chinese milk vetch honey, on wound healing in comparison with hydrocolloid dressing. Circular full-thickness skin wounds were produced on male mice. Japanese honey or hydrocolloid dressing was applied daily to the mice for 14 days. The ratio of wound area for the hydrocolloid dressing group increased initially in the inflammatory and early proliferative phases and then decreased rapidly to heal with scarring. However, the ratios of wound area for the Japanese honey groups decreased in the inflammatory phase, increased in the proliferative phase, and decreased in the proliferative phase, and some wounds were not completely covered with new epithelium. These findings indicate that using Japanese honey alone has limited benefit, but since it reduces wound size in the inflammatory phase, it is possible to apply a combined treatment in which Japanese honey is applied only in the inflammatory phase, followed by hydrocolloid dressing from the proliferative phase, which would effectively contract the wound

Oleanolic acid controls allergic and inflammatory responses in experimental allergic conjunctivitis

This is an open-access article distributed under the terms of the Creative Commons Attribution License.Pollen is the most common aeroallergen to cause seasonal conjunctivitis. The result of allergen exposure is a strong Th2-mediated response along with conjunctival mast cell degranulation and eosinophilic infiltration. Oleanolic acid (OA) is natural a triterpene that displays strong anti-inflammatory and immunomodulatory properties being an active anti-allergic molecule on hypersensitivity reaction models. However, its effect on inflammatory ocular disorders including conjunctivits, has not yet been addressed. Hence, using a Ragweed pollen (RWP)-specific allergic conjunctivitis (EAC) mouse model we study here whether OA could modify responses associated to allergic processes. We found that OA treatment restricted mast cell degranulation and infiltration of eosinophils in conjunctival tissue and decreased allergen-specific Igs levels in EAC mice. Th2-type cytokines, secreted phospholipase A2 type-IIA (sPLA2-IIA), and chemokines levels were also significantly diminished in the conjunctiva and serum of OA-treated EAC mice. Moreover, OA treatment also suppressed RWP-specific T-cell proliferation. In vitro studies, on relevant cells of the allergic process, revealed that OA reduced the proliferative and migratory response, as well as the synthesis of proinflammatory mediators on EoL-1 eosinophils and RBL-2H3 mast cells exposed to allergic and/or crucial inflammatory stimuli such as RWP, sPLA2-IIA or eotaxin. Taken together, these findings demonstrate the beneficial activity of OA in ocular allergic processes and may provide a new intervention strategy and potential therapy for allergic diseases. © 2014 Córdova et al.The study was supported by grants from the Spanish MINECO (reference SAF2009-08407). Patricia Gallego-Muñoz and Claudia Cordova were funded by the FPI Program from the Government of Castilla y León (co-funded by FSE). Rubén Martín was supported by the Sara Borrell Program from the Spanish MINECO.Peer Reviewe

Infiltration of COX-2–expressing macrophages is a prerequisite for IL-1β–induced neovascularization and tumor growth

Inflammatory angiogenesis is a critical process in tumor progression and other diseases. The inflammatory cytokine IL-1β promotes angiogenesis, tumor growth, and metastasis, but its mechanisms remain unclear. We examined the association between IL-1β–induced angiogenesis and cell inflammation. IL-1β induced neovascularization in the mouse cornea at rates comparable to those of VEGF. Neutrophil infiltration occurred on day 2. Macrophage infiltration occurred on days 4 and 6. The anti–Gr-1 Ab-induced depletion of infiltrating neutrophils did not affect IL-1β– or VEGF-induced angiogenesis. The former was reduced in monocyte chemoattractant protein-1–deficient (MCP-1(–/–)) mice compared with wild-type mice. After day 4, clodronate liposomes, which kill macrophages, reduced IL-1β–induced angiogenesis and partially inhibited VEGF-induced angiogenesis. Infiltrating macrophages near the IL-1β–induced neovasculature were COX-2 positive. Lewis lung carcinoma cells expressing IL-1β (LLC/IL-1β) developed neovasculature with macrophage infiltration and enhanced tumor growth in wild-type but not MCP-1(–/–) mice. A COX-2 inhibitor reduced tumor growth, angiogenesis, and macrophage infiltration in LLC/IL-1β. Thus, macrophage involvement might be a prerequisite for IL-1β–induced neovascularization and tumor progression