2,586 research outputs found
Introduction to Library Trends 53 (3) Winter 2005: Consumer Health Issues, Trends, and Research, Part 2: Applicable Research in the 21st Century
published or submitted for publicatio
Space Station Technology, 1983
This publication is a compilation of the panel summaries presented in the following areas: systems/operations technology; crew and life support; EVA; crew and life support: ECLSS; attitude, control, and stabilization; human capabilities; auxillary propulsion; fluid management; communications; structures and mechanisms; data management; power; and thermal control. The objective of the workshop was to aid the Space Station Technology Steering Committee in defining and implementing a technology development program to support the establishment of a permanent human presence in space. This compilation will provide the participants and their organizations with the information presented at this workshop in a referenceable format. This information will establish a stepping stone for users of space station technology to develop new technology and plan future tasks
Dna2 Helicase/Nuclease Causes Replicative Fork Stalling and Double-strand Breaks in the Ribosomal DNA of Saccharomyces cerevisiae
We have proposed that faulty processing of arrested replication forks leads to increases in recombination and chromosome instability in Saccharomyces cerevisiae and contributes to the shortened lifespan of dna2 mutants. Now we use the ribosomal DNA locus, which is a good model for all stages of DNA replication, to test this hypothesis. We show directly that DNA replication pausing at the ribosomal DNA replication fork barrier (RFB) is accompanied by the occurrence of double-strand breaks near the RFB. Both pausing and breakage are elevated in the early aging, hypomorphic dna2-2 helicase mutant. Deletion of FOB1, encoding the fork barrier protein, suppresses the elevated pausing and DSB formation, and represses initiation at rDNA ARSs. The dna2-2 mutation is synthetically lethal with {Delta}rrm3, encoding another DNA helicase involved in rDNA replication. It does not appear to be the case that the rDNA is the only determinant of genome stability during the yeast lifespan however since strains carrying deletion of all chromosomal rDNA but with all rDNA supplied on a plasmid, have decreased rather than increased lifespan. We conclude that the replication-associated defects that we can measure in the rDNA are symbolic of similar events occurring either stochastically throughout the genome or at other regions where replication forks move slowly or stall, such as telomeres, centromeres, or replication slow zones
Privatization of Municipal Services: A Contagion in the Body Politic
Our cities are experiencing severe financial and sociological difficulties. Last year, more cities than ever finished the year with deficits. Tax bases are eroding as both private individuals and businesses flee cities to the comforting arms of suburbs and foreign markets. Those residents remaining within the cities\u27 boundaries are loathe to pass tax increases to pay for the increased costs of providing social services to an urban population that is becoming more and more needy. As cities become increasingly desperate to tap new revenue sources in order to squeeze more out of already flattened budgets, and seek to revitalize community pride, many administrations are beginning to seek the privatization of public services as an alternative to ruin. However, private parties are not the appropriate entities to provide certain public services. Governments cannot turn over the operation of essential governmental services to private companies without abusing the trust of their citizens and circumventing the Constitution. Therefore, privatization is not the panacea that many governments believe
REVISIONING REALITY: NORMATIVE RESISTANCE IN THE CULTURAL WORKS OF THE LINCOLN MOTION PICTURE COMPANY, NELLA LARSEN, AND ALLAN ROHAN CRITE, 1915-1945
Despite the fact that nineteenth and twentieth century biologist and Social Darwinists theories of race have been dispelled, the social residue of white supremacist ideologies continue to have social and political implications throughout American society. America\u27s racial hierarchy, and whiteness as a social and racial construct instantiated within it, against which every other group of people has been relationally situated, has helped not only to define non-white racial subjects in inferior terms, it has also guaranteed a perpetuation of race-based structural and social inequalities in United States of America. African American Studies, Critical Race Theory, Whiteness Studies, and most recently a body of Normalcy scholarship have examined not only the immensity and reach of power that whiteness has a construct in American society, but the ability of this construct to operate in society as an invisible and largely un-interrogated force. This is because of how whiteness is often represented as neutral, disinterested, and normal. This dissertation examines three early twentieth century African American cultural producers who deployed representations of normativity as acts of artistic expression, political critique and social resistance. This dissertation argues that The Lincoln Motion Picture Company (1916-1923), writer Nella Larsen (1891-1964), and painter Allan Rohan Crite (1910-2007) used narrative forms to construct a politics of normativity through which they critiqued U.S. racial politics and challenged racist discourses aimed at African Americans in the early twentieth century. These artists deployed representations of normativity as an antiracist strategy through which to respond to U.S. racial hierarchies in the public realm, which persistently represented African Americans as non-normative, inferior and social deviant subjects. This dissertation joins ongoing discussions by scholars in the fields of American Studies, African American Studies, Women\u27s Studies, Cultural Studies and Visual Culture and Literary Studies investigating strategies of representations, as forms of resistance, and what these strategies reveal about social, cultural and political negotiations made by marginalized subjects in U.S. national culture
Challenges for Global Learners: A Qualitative Study of the Concerns and Difficulties of International Students
The authors in this study seek to inform academia about international students’ experiences and challenges while attending universities in Small Town USA. Despite their eagerness to study in the United States (U.S.), international students are faced with setbacks that many universities fail to recognize or realize. The researchers conducted in-depth interviews with a purposive sample of students using questions based on information from the literature and an initial survey. The themes that emerged from the data analysis were language, jobs/finances, transportation, assimilation, religious interactions, and identity. Findings emphasize the imperative to understand the challenges these students face as they continue their educational journeys in the United States
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