Presence: A Mechanism for Developing Rapport in Physician Interprofessional Engagement

Inspired by my work as a coach in an academic medical center, this paper explores the mechanisms of presence and mindfulness as axioms to developing rapport within physician interprofessional engagement. Away from the physician-patient relationship, the focus here is on faculty, physicians, residents, and other clinical providers and how they relate to one another. Transpersonal experiences foster a connectedness of rapport that allows for deeper connection and mutuality. Participation in the mindfulness mechanisms of intention and attention can mitigate negative affective behavior in relationship with oneself and others. Mindful awareness encourages curiosity, presence, and rapport, which support healthy relationships. My coaching engagements with physicians focus on shifting their awareness to conscious choice with intention. It is not about how they practice medicine but how they practice presence and rapport toward developing healthy interprofessional relationships

Conservation of a Coptic Tunic Fragment

"In 1979 the Museum acquired half of a Coptic tunic as a gift. It arrived in the Museum neatly folded in a padded envelope measuring 10 x 14 inches. Upon inspection, the fabric appeared to be relatively supple, and it was decided that unfolding the fabric would not cause too much harm. What follows here is the report of the subsequent conservation measures taken to stabilize one of the largest and best archaeological textiles in the Museum's collection."--First paragraph.Includes bibliographical reference

Combining social network analysis and sentiment analysis to explore the potential for online radicalisation

The increased online presence of jihadists has raised the possibility of individuals being radicalised via the Internet. To date, the study of violent radicalisation has focused on dedicated jihadist websites and forums. This may not be the ideal starting point for such research, as participants in these venues may be described as “already madeup minds”. Crawling a global social networking platform, such as YouTube, on the other hand, has the potential to unearth content and interaction aimed at radicalisation of those with little or no apparent prior interest in violent jihadism. This research explores whether such an approach is indeed fruitful. We collected a large dataset from a group within YouTube that we identified as potentially having a radicalising agenda. We analysed this data using social network analysis and sentiment analysis tools, examining the topics discussed and what the sentiment polarity (positive or negative) is towards these topics. In particular, we focus on gender differences in this group of users, suggesting most extreme and less tolerant views among female users

Molecular characterization of SSS139, a new satellite DNA family in sibling species of the Drosophila buzzatii cluster

We characterized sequences of a novel SSS139 RsaI satellite DNA family in Drosophila gouveai and Drosophila seriema, two members of the Drosophila buzzatii cluster (D. repleta group). The sequences were AT-rich (69%) with a monomer unit length of about 139 bp and contained two direct subrepeats of 14 bp and 16 bp, suggesting that it might have originated by the duplication of smaller sequences. Southern and dot-blot hybridization analyses also detected SSS139 in other Drosophila buzzatii cluster species (D. koepferae, D. antonietae, D. borborema and D. serido) but not in D. buzzatii. These results agree with the marginal phylogenetic position of D. buzzatii within the D. buzzatii cluster.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)FINEP - Financiadora de Estudos e Projeto

Stability of casein micelles cross-linked with genipin: a physicochemical study as a function of pH

Chemical or enzymatic cross-linking of casein micelles (CMs) increases their stability against dissociating agents. In this paper, a comparative study of stability between native CMs and CMs cross-linked with genipin (CMs-GP) as a function of pH is described. Stability to temperature and ethanol were investigated in the pH range 2.0-7.0. The size and the charge ($\zeta$-potential) of the particles were determined by dynamic light scattering. Native CMs precipitated below pH 5.5, CMs-GP precipitated from pH 3.5 to 4.5, whereas no precipitation was observed at pH 2.0-3.0 or pH 4.5-7.0. The isoelectric point of CMs-GP was determined to be pH 3.7. Highest stability against heat and ethanol was observed for CMs-GP at pH 2, where visible coagulation was determined only after 800 s at 140 $^\circ$C or 87.5% (v/v) of ethanol. These results confirmed the hypothesis that cross-linking by GP increased the stability of CMs.Comment: 5 pages, 2 figures, International Dairy Journal, 201

Receptor-Receptor Interactions as a Widespread Phenomenon: Novel Targets for Drug Development?

open5The discovery of receptor-receptor interactions (RRI) has expanded our understanding of the role that G protein-coupled receptors (GPCRs) play in intercellular communication. The finding that GPCRs can operate as receptor complexes, and not only as monomers, suggests that several different incoming signals could already be integrated at the plasma membrane level via direct allosteric interactions between the protomers that form the complex. Most research in this field has focused on neuronal populations and has led to the identification of a large number of RRI. However, RRI have been seen to occur not only in neurons but also in astrocytes and, outside the central nervous system, in cells of the cardiovascular and endocrine systems and in cancer cells. Furthermore, RRI involving the formation of macromolecular complexes are not limited to GPCRs, being also observed in other families of receptors. Thus, RRI appear as a widespread phenomenon and oligomerization as a common mechanism for receptor function and regulation. The discovery of these macromolecular assemblies may well have a major impact on pharmacology. Indeed, the formation of receptor complexes significantly broadens the spectrum of mechanisms available to receptors for recognition and signaling, which may be implemented through modulation of the binding sites of the adjacent protomers and of their signal transduction features. In this context, the possible appearance of novel allosteric sites in the receptor complex structure may be of particular relevance. Thus, the existence of RRI offers the possibility of new therapeutic approaches, and novel pharmacological strategies for disease treatment have already been proposed. Several challenges, however, remain. These include the accurate characterization of the role that the receptor complexes identified so far play in pathological conditions and the development of ligands specific to given receptor complexes, in order to efficiently exploit the pharmacological properties of these complexes.openGuidolin, Diego; Marcoli, Manuela; Tortorella, Cinzia; Maura, Guido; Agnati, Luigi FGuidolin, Diego; Marcoli, Manuela; Tortorella, Cinzia; Maura, Guido; Agnati, Luigi

The mobility of Atlantic baric depressions leading to intense precipitation over Italy: a preliminary statistical analysis

International audienceThe speed of Atlantic surface depressions, occurred during the autumn and winter seasons and that lead to intense precipitation over Italy from 1951 to 2000, was investigated. Italy was divided into 5 regions as documented in previous climatological studies (based on Principal Component Analysis). Intense precipitation events were selected on the basis of in situ rain gauge data and clustered according to the region that they hit. For each intense precipitation event we tried to identify an associated surface depression and we tracked it, within a large domain covering the Mediterranean and Atlantic regions, from its formation to cyclolysis in order to estimate its speed. "Depression speeds" were estimated with 6-h resolution and clustered into slow and non-slow classes by means of a threshold, coinciding with the first quartile of speed distribution and depression centre speeds were associated with their positions. Slow speeds occurring over an area including Italy and the western Mediterranean basin showed frequencies higher than 25%, for all the Italian regions but one. The probability of obtaining by chance the observed more than 25% success rate was estimated by means of a binomial distribution. The statistical reliability of the result is confirmed for only one region. For Italy as a whole, results were confirmed at 95% confidence level. Stability of the statistical inference, with respect to errors in estimating depression speed and changes in the threshold of slow depressions, was analysed and essentially confirmed the previous results