223 research outputs found
Simulating Astro-E2 Observations of Galaxy Clusters: the Case of Turbulent Cores Affected by Tsunamis
This is the first attempt to construct detailed X-ray spectra of clusters of
galaxies from the results of high-resolution hydrodynamic simulations and
simulate X-ray observations in order to study velocity fields of the
intracluster medium (ICM). The hydrodynamic simulations are based on the
recently proposed tsunami model, in which cluster cores are affected by bulk
motions of the ICM and turbulence is produced. We note that most other
solutions of the cooling flow problem also involve the generation of turbulence
in cluster cores. From the mock X-ray observations with Astro-E2 XRS, we find
that turbulent motion of the ICM in cluster cores could be detected with the
satellite. The Doppler shifts of the metal lines could be used to discriminate
among turbulence models. The gas velocities measured through the mock
observations are consistent with the line-emission weighted values inferred
directly from hydrodynamic simulations.Comment: 13 pages, 2 figures, ApJL in press. Movies are available at
http://th.nao.ac.jp/tsunami/index.ht
Hypersensitive Reaction to Praziquantel in a Clonorchiasis Patient
Praziquantel is the drug of choice for clonorchiasis. Since clonorchiasis is endemic in most river basins, praziquantel has been widely used for 30 years in Korea. A 54-year-old Korean woman suffered from hypersensitive reactions, such as nausea, dyspnea, rash, and urticaria after taking the first dose of praziquantel to treat clonorchiasis. She ingested one dose again and the same symptoms appeared, and she was treated at a clinic with anti-histamines. She tried one more dose with anti-histamines but found the same symptoms. Later, she was found to pass eggs of Clonorchis sinensis and medicated with flubendazole. The hypersensitive reaction to praziquantel is rare but occurs. This is the 5th case report in the world
The Effects of Intradermal Vaccination with DNA Encoding for the T-cell Receptor on the Induction of Experimental Autoimmune Encephalomyelitis in B10.PL Mice
Intradermal gene administration was found to induce a more profound immune response than direct intramusclular gene injection. We performed intradermal vaccination of B10.PL mice with DNA encoding for the Vβ8.2 region of the T-cell receptors (TCR). Three weeks later, these mice were immunized with rat myelin basic protein (MBP). Daily mean clinical scores and mortality rate were lower in this group compared with controls. The proliferative responses of lymph node cells to rat MBP were slightly less in the vaccination groups than in the control groups (p<0.05). However, we detected no differences between the two groups with regard to the production of MBP-specific IgG, IgG1, & IgG2a antibodies. The levels of cytokine mRNA expression in the vaccination groups were observed higher than in the control groups without antigen-specific stimulation, but all of cytokine expressions between the vaccination and control groups after antigen-specific stimulation were identical. These results demonstrate that intradermal DNA vaccines encoding for TCR might prove to be useful in the control of autoimmune disease
A Newly Formed and Ruptured Atheromatous Plaque within Neointima after Drug-Eluting Stent Implantation: 2-Year Follow-Up Intravascular Ultrasound and Optical Coherence Tomography Studies
Late stent thrombosis (LST) which is a life threatening complication has emerged as a serious problem of drug-eluting stents (DES). Several studies have suggested that incomplete neointimal coverage of stent struts contributes to LST. Progressive atherosclerosis within the neointima is an another possible cause of LST, but this phenomenon has seldom been reported in DES. We present a case of LST following DES implantation after a period of 28 months due to ruptured atheromatous plaque, despite complete neointimal coverage of stent struts proven by optical coherence tomography
Early gastric cancer arising from heterotopic gastric mucosa in the gastric submucosa
The incidence of heterotopic gastric mucosa located in the submucosa in resected stomach specimens has been reported to be 3.0 to 20.1%. Heterotopic gastric mucosa is thought to be a benign disease, which rarely becomes malignant. Heterotopic gastric mucosa exists in the gastric submucosa, and gastric cancer rarely occurs in heterotopic gastric mucosa. Since tumors are located in the normal submucosa, they appear as submucosal tumors during endoscopy, and are diagnosed through endoscopic biopsies with some difficulty. For such reasons, heterotopic gastric mucosa is mistaken as gastric submucosal tumor. Recently, two cases of early gastric cancer arising from heterotopic gastric mucosa in the gastric submucosa were treated. Both cases were diagnosed as submucosal tumors based on upper gastrointestinal endoscopy, endoscopic ultrasound, and computed tomography findings, and in both cases, laparoscopic wedge resections were performed, the surgical findings of which also suggested submucosal tumors. However, pathologic assessment of the surgical specimens led to the diagnosis of well-differentiated intramucosal adenocarcinoma arising from heterotopic gastric mucosa in the gastric submucosa
The First Very Long Baseline Interferometry Image of 44 GHz Methanol Maser with the KVN and VERA Array (KaVA)
We have carried out the first very long baseline interferometry (VLBI)
imaging of 44 GHz class I methanol maser (7_{0}-6_{1}A^{+}) associated with a
millimeter core MM2 in a massive star-forming region IRAS 18151-1208 with KaVA
(KVN and VERA Array), which is a newly combined array of KVN (Korean VLBI
Network) and VERA (VLBI Exploration of Radio Astrometry). We have succeeded in
imaging compact maser features with a synthesized beam size of 2.7
milliarcseconds x 1.5 milliarcseconds (mas). These features are detected at a
limited number of baselines within the length of shorter than approximately 650
km corresponding to 100 Mlambda in the uv-coverage. The central velocity and
the velocity width of the 44 GHz methanol maser are consistent with those of
the quiescent gas rather than the outflow traced by the SiO thermal line. The
minimum component size among the maser features is ~ 5 mas x 2 mas, which
corresponds to the linear size of ~ 15 AU x 6 AU assuming a distance of 3 kpc.
The brightness temperatures of these features range from ~ 3.5 x 10^{8} to 1.0
x 10^{10} K, which are higher than estimated lower limit from a previous Very
Large Array observation with the highest spatial resolution of ~ 50 mas. The 44
GHz class I methanol maser in IRAS 18151-1208 is found to be associated with
the MM2 core, which is thought to be less evolved than another millimeter core
MM1 associated with the 6.7 GHz class II methanol maser.Comment: 19 pages, 3 figure
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