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CO and CI maps of the starburst galaxy M82
The first map of an external galaxy in the 3P₁ - 3P0 fine-structure line of atomic carbon (CI) is presented towards the nucleus of the starbuster M82, and compared with the distinction of the CO J = 4 - 3 molecular emission. The CI traces features that are seen in lower transition CO maps, and shows that CI and the CO are well mixed and have similar spatial distributions. There are small differences between the CO J = 4 - 3 line and lower transition CO data towards the NE part of the molecular ring, where the emission is less prominent. The abundance ratio [CI]/[CO] across M82 is very high, with an average value ~ 0.5 across most of the nucleus, a factor at least 5 times that which is typical of dense molecular cloud cores seen in our own Galaxy. This means that on average, CI is overabundant towards M82. This result can be explained using models which provide enhancements to the CI abundance above normal Interstellar Medium values, a result of a greater cosmic ray flux in M82, or where there is substantial mixing of the gas
Protein folding rates correlate with heterogeneity of folding mechanism
By observing trends in the folding kinetics of experimental 2-state proteins
at their transition midpoints, and by observing trends in the barrier heights
of numerous simulations of coarse grained, C-alpha model, Go proteins, we show
that folding rates correlate with the degree of heterogeneity in the formation
of native contacts. Statistically significant correlations are observed between
folding rates and measures of heterogeneity inherent in the native topology, as
well as between rates and the variance in the distribution of either
experimentally measured or simulated phi-values.Comment: 11 pages, 3 figures, 1 tabl
Understanding the Effects of Repetitive Transcranial Magnetic Stimulation on Neuronal Circuits
Despite the widespread use of repetitive transcranial magnetic stimulation (rTMS) in both research and clinical settings, there is a paucity of evidence regarding the effects of its application on neural activity. Studies investigating the effects of rTMS on human participants (Huang et al., 2005) have shown that patterned trains of rTMS can be used to modulate the sensitivity of motor pathways for a period outlasting the stimulation itself. These changes are often attributed to an rTMS-induced increase in neural plasticity or a change in excitability of the motor pathway. Evidence that rTMS can modify the strength of motor pathways has led to its introduction into stroke rehabilitation research. It is hypothesized that post-stroke, rTMS can enhance plasticity induction within the brain and, when combined with manual therapy, can facilitate surviving neurons assuming the function of those lost to the stroke (Hsu et al., 2012). In practice however, despite a multitude of studies investigating this approach, there remains no convincing evidence that rTMS is capable of promoting sustained long-term improvement in recovery, above the effects of rehabilitation alone (Hsu et al., 2012; Lefaucheur et al., 2014). We are of the opinion that a lack of advancement within the field is due to an incomplete understanding of the effects of TMS on neural elements. Here we discuss some of the existing evidence and propose experimental approaches that may enhance the human application of rTMS
Evidence for Asphericity in the Type IIn Supernova 1998S
We present optical spectropolarimetry obtained at the Keck-II 10-m telescope
on 1998 March 7 UT along with total flux spectra spanning the first 494 days
after discovery (1998 March 2 UT) of the peculiar type IIn supernova (SN)
1998S. The SN is found to exhibit a high degree of linear polarization,
implying significant asphericity for its continuum-scattering environment.
Prior to removal of the interstellar polarization, the polarization spectrum is
characterized by a flat continuum (at p ~ 2%) with distinct changes in
polarization associated with both the broad (FWZI >= 20,000 km/s) and narrow
(unresolved, FWHM < 300 km/s) line emission seen in the total flux spectrum.
When analyzed in terms of a polarized continuum with unpolarized broad-line
recombination emission, an intrinsic continuum polarization of p ~ 3% results
(the highest yet found for a SN), suggesting a global asphericity of >= 45%
from the oblate, electron-scattering dominated models of Hoflich (1991). The
smooth, blue continuum evident at early times is shown to be inconsistent with
a reddened, single-temperature blackbody, instead having a color temperature
that increases with decreasing wavelength. Broad emission-line profiles with
distinct blue and red peaks are seen in the total flux spectra at later times,
perhaps suggesting a disk-like or ring-like morphology for the dense (n_e ~
10^7 cm^{-3}) circumstellar medium. Implications of the circumstellar
scattering environment for the spectropolarimetry are discussed, as are the
effects of uncertain removal of interstellar polarization.Comment: 25 pages + 2 tables + 14 figures, Submitted to The Astrophysical
Journa
Chandra Observations of Type Ia Supernovae: Upper Limits to the X-ray Flux of SN 2002bo, SN 2002ic, SN 2005gj, and SN 2005ke
We set sensitive upper limits to the X-ray emission of four Type Ia
supernovae (SNe Ia) using the Chandra X-ray Observatory. SN 2002bo, a normal,
although reddened, nearby SN Ia, was observed 9.3 days after explosion. For an
absorbed, high temperature bremsstrahlung model the flux limits are 3.2E-16
ergs/cm^2/s (0.5-2 keV band) and 4.1E-15 ergs/cm^2/s (2-10 keV band). Using
conservative model assumptions and a 10 km/s wind speed, we derive a mass loss
rate of \dot{M} ~ 2E-5 M_\odot/yr, which is comparable to limits set by the
non-detection of Halpha lines from other SNe Ia. Two other objects, SN 2002ic
and SN 2005gj, observed 260 and 80 days after explosion, respectively, are the
only SNe Ia showing evidence for circumstellar interaction. The SN 2002ic X-ray
flux upper limits are ~4 times below predictions of the interaction model
currently favored to explain the bright optical emission. To resolve this
discrepancy we invoke the mixing of cool dense ejecta fragments into the
forward shock region, which produces increased X-ray absorption. A modest
amount of mixing allows us to accommodate the Chandra upper limit. SN 2005gj is
less well studied at this time. Assuming the same circumstellar environment as
for SN 2002i, the X-ray flux upper limits for SN 2005gj are ~4 times below the
predictions, suggesting that mixing of cool ejecta into the forward shock has
also occurred here. Our reanalysis of Swift and Chandra data on SN 2005ke does
not confirm a previously reported X-ray detection. The host galaxies NGC 3190
(SN 2002bo) and NGC 1371 (SN 2005ke) each harbor a low luminosity (L_X ~ 3-4E40
ergs/s) active nucleus in addition to wide-spread diffuse soft X-ray emission.Comment: 16 pages, to appear in ApJ (20 Nov 2007
The Supernova Gamma-Ray Burst Connection
The chief distinction between ordinary supernovae and long-soft gamma-ray
bursts (GRBs) is the degree of differential rotation in the inner several solar
masses when a massive star dies, and GRBs are rare mainly because of the
difficulty achieving the necessary high rotation rate. Models that do provide
the necessary angular momentum are discussed, with emphasis on a new single
star model whose rapid rotation leads to complete mixing on the main sequence
and avoids red giant formation. This channel of progenitor evolution also gives
a broader range of masses than previous models, and allows the copious
production of bursts outside of binaries and at high redshifts. However, even
the production of a bare helium core rotating nearly at break up is not, by
itself, a sufficient condition to make a gamma-ray burst. Wolf-Rayet mass loss
must be low, and will be low in regions of low metallicity. This suggests that
bursts at high redshift (low metallicity) will, on the average, be more
energetic, have more time structure, and last longer than bursts nearby. Every
burst consists of three components: a polar jet (~0.1 radian), high energy,
subrelativistic mass ejection (~1 radian), and low velocity equatorial mass
that can fall back after the initial explosion. The relative proportions of
these three components can give a diverse assortment of supernovae and high
energy transients whose properties may vary with redshift.Comment: 10 pages, to appear in AIP Conf. Proc. "Gamma Ray Bursts in the Swift
Era", Eds. S. S. Holt, N. Gehrels, J. Nouse
PHotometry Assisted Spectral Extraction (PHASE) and identification of SNLS supernovae
Aim: We present new extraction and identification techniques for supernova
(SN) spectra developed within the Supernova Legacy Survey (SNLS) collaboration.
Method: The new spectral extraction method takes full advantage of
photometric information from the Canada-France-Hawai telescope (CFHT) discovery
and reference images by tracing the exact position of the supernova and the
host signals on the spectrogram. When present, the host spatial profile is
measured on deep multi-band reference images and is used to model the host
contribution to the full (supernova + host) signal. The supernova is modelled
as a Gaussian function of width equal to the seeing. A chi-square minimisation
provides the flux of each component in each pixel of the 2D spectrogram. For a
host-supernova separation greater than <~ 1 pixel, the two components are
recovered separately and we do not use a spectral template in contrast to more
standard analyses. This new procedure permits a clean extraction of the
supernova separately from the host in about 70% of the 3rd year ESO/VLT spectra
of the SNLS. A new supernova identification method is also proposed. It uses
the SALT2 spectrophotometric template to combine the photometric and spectral
data. A galaxy template is allowed for spectra for which a separate extraction
of the supernova and the host was not possible.
Result: These new techniques have been tested against more standard
extraction and identification procedures. They permit a secure type and
redshift determination in about 80% of cases. The present paper illustrates
their performances on a few sample spectra.Comment: 27 pages, 18 Figures, 1 Table. Accepted for publication in A&
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