899 research outputs found

    A model for single electron decays from a strongly isolated quantum dot

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    Recent measurements of electron escape from a non-equilibrium charged quantum dot are interpreted within a 2D separable model. The confining potential is derived from 3D self-consistent Poisson-Thomas-Fermi calculations. It is found that the sequence of decay lifetimes provides a sensitive test of the confining potential and its dependence on electron occupation.Comment: 9 pages, 10 figure

    Memory effects induced by initial switching conditions

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    Initial-switching refers to the way in which the decay of an initially confined state begins, as the barrier isolating it from the exterior is relaxed. We study these effects in the context of Longhi's version of the Fano-Anderson model. Most authors assume the sudden approximation where the coupling is turned on instantaneously. We consider a finite rise time T, both numerically and analytically. When the coupling is ramped up linearly over a switching time T, we show that the asymptotic survival amplitude acquires a phase T and is modulated by a factor (sin T)/T. Several other results relating to the solution of the model are obtained. All site amplitudes have the same decay constant during the exponential decay regime. In the asymptotic regime, the amplitude and phase of decay oscillations depend on the initial-switching profile, but the period does not.Comment: 12 pages, 10 figures, accepted by Phys. Rev.

    Compression of the Left Innominated Vein between the Brachiocephalic Trunk and Left Carotid Artery

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    AbstractWe present a case of a 25-year-old male who looked for medical attention for symptoms like dysesthesias in his left arm. Physical examination revealed severe dilations of the superficial veins in his left forearm and arm.An ultrasound showed no signs of thrombosis. Dynamic phlebography ruled out the presence of extrinsic compression of the left innominated vein. The angioMRI confirmed that the innominated vein was compressed between the braquiocephalic trunk and left carotid.Therefore, we describe a previously unreported congenital anomaly of the left brachiocephalic vein where the fundamental symptom is the compression of the left innominated trunk

    Mutations in the EXT1 and EXT2 genes in Spanish patients with multiple osteochondromas

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    Multiple osteochondromas is an autosomal dominant skeletal disorder characterized by the formation of multiple cartilage-capped tumours. Two causal genes have been identified, EXT1 and EXT2, which account for 65% and 30% of cases, respectively. We have undertaken a mutation analysis of the EXT1 and EXT2 genes in 39 unrelated Spanish patients, most of them with moderate phenotype, and looked for genotype-phenotype correlations. We found the mutant allele in 37 patients, 29 in EXT1 and 8 in EXT2. Five of the EXT1 mutations were deletions identified by MLPA. Two cases of mosaicism were documented. We detected a lower number of exostoses in patients with missense mutation versus other kinds of mutations. In conclusion, we found a mutation in EXT1 or in EXT2 in 95% of the Spanish patients. Eighteen of the mutations were novel.Fil: Sarrión, P.. Universidad de Barcelona; EspañaFil: Sangorrin, A.. Hospital Sant Joan de Déu; EspañaFil: Urreizti, R.. Universidad de Barcelona; EspañaFil: Delgado, María Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Córdoba; ArgentinaFil: Artuch, R.. Hospital Sant Joan de Déu; EspañaFil: Martorell, L.. Hospital Sant Joan de Déu; EspañaFil: Armstrong, J.. Hospital Sant Joan de Déu; EspañaFil: Anton, J.. Hospital Sant Joan de Déu; EspañaFil: Torner, F.. Hospital Sant Joan de Déu; EspañaFil: Vilaseca, M. A.. Hospital Sant Joan de Déu; EspañaFil: Nevado, J.. Hospital Universitario La Paz; EspañaFil: Lapunzina, P.. Hospital Universitario La Paz; EspañaFil: Asteggiano, Carla Gabriela. Universidad Nacional de Córdoba; Argentina. Universidad Católica de Córdoba; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Balcells, S.. Universidad de Barcelona; EspañaFil: Grinberg, D.. Universidad de Barcelona; Españ

    Combined Treatment with Open and Endovascular Surgery of a Mycotic Abdominal Aortic Aneurysm

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    AbstractWe report the treatment of a 67-year-old male patient with a suprarenal mycotic aortic aneurysm. A 67-year-old male developed renal failure during the treatment of a urine infection and a paracervical abscess. Further investigations revealed a 5.6cm saccular suprarenal abdominal aortic aneurysm. A successful combined treatment was carried out with endovascular techniques and open surgery, realizing a retrograde aorto-superior mesenteric bypass. Postoperative follow up scans showed exclusion and thrombosis of the aneurysm. Treatment of mycotic aneurysms is mainly surgical, but endovascular therapy helps to avoid highly complicated surgery and reduces mortality

    Long time deviation from exponential decay: non-integral power laws

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    Quantal systems are predicted to show a change-over from exponential decay to power law decay at very long times. Although most theoretical studies predict integer power-law exponents, recent measurements by Rothe et al. of decay luminescence of organic molecules in solution {Phys. Rev. Lett. 96 (2006) 163601} found non-integer exponents in most cases. We propose a physical mechanism, within the realm of scattering from potentials with long tails, which produces a continuous range of power law exponents. In the tractable case of the repulsive inverse square potential, we demonstrate a simple relation between the strength of the long range tail and the power law exponent. This system is amenable to experimental scrutiny

    A simple formula for the L-gap width of a face-centered-cubic photonic crystal

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    The width L\triangle_L of the first Bragg's scattering peak in the (111) direction of a face-centered-cubic lattice of air spheres can be well approximated by a simple formula which only involves the volume averaged ϵ\epsilon and ϵ2\epsilon^2 over the lattice unit cell, ϵ\epsilon being the (position dependent) dielectric constant of the medium, and the effective dielectric constant ϵeff\epsilon_{eff} in the long-wavelength limit approximated by Maxwell-Garnett's formula. Apparently, our formula describes the asymptotic behaviour of the absolute gap width L\triangle_L for high dielectric contrast δ\delta exactly. The standard deviation σ\sigma steadily decreases well below 1% as δ\delta increases. For example σ<0.1\sigma< 0.1% for the sphere filling fraction f=0.2f=0.2 and δ20\delta\geq 20. On the interval δ(1,100)\delta\in(1,100), our formula still approximates the absolute gap width L\triangle_L (the relative gap width Lr\triangle_L^r) with a reasonable precision, namely with a standard deviation 3% (4.2%) for low filling fractions up to 6.5% (8%) for the close-packed case. Differences between the case of air spheres in a dielectric and dielectric spheres in air are briefly discussed.Comment: 13 pages, 4 figs., RevTex, two references added. For more info see http://www.amolf.nl/external/wwwlab/atoms/theory/index.htm

    Parametric localized modes in quadratic nonlinear photonic structures

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    We analyze two-color spatially localized modes formed by parametrically coupled fundamental and second-harmonic fields excited at quadratic (or chi-2) nonlinear interfaces embedded into a linear layered structure --- a quasi-one-dimensional quadratic nonlinear photonic crystal. For a periodic lattice of nonlinear interfaces, we derive an effective discrete model for the amplitudes of the fundamental and second-harmonic waves at the interfaces (the so-called discrete chi-2 equations), and find, numerically and analytically, the spatially localized solutions --- discrete gap solitons. For a single nonlinear interface in a linear superlattice, we study the properties of two-color localized modes, and describe both similarities and differences with quadratic solitons in homogeneous media.Comment: 9 pages, 8 figure

    Quercetin Impact in Pancreatic Cancer: An Overview on Its Therapeutic Effects

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    Pancreatic cancer (PC) is a lethal malignancy cancer, and its mortality rates have been increasing worldwide. Diagnosis of this cancer is complicated, as it does not often present symptoms, and most patients present an irremediable tumor having a 5-year survival rate after diagnosis. Regarding treatment, many concerns have also been raised, as most tumors are found at advanced stages. At present, anticancer compounds-rich foods have been utilized to control PC. Among such bioactive molecules, flavonoid compounds have shown excellent anticancer abilities, such as quercetin, which has been used as an adjunctive or alternative drug to PC treatment by inhibitory or stimulatory biological mechanisms including autophagy, apoptosis, cell growth reduction or inhibition, EMT, oxidative stress, and enhancing sensitivity to chemotherapy agents. The recognition that this natural product has beneficial effects on cancer treatment has boosted the researchers’ interest towards more extensive studies to use herbal medicine for anticancer purposes. In addition, due to the expensive cost and high rate of side effects of anticancer drugs, attempts have been made to use quercetin but also other flavonoids for preventing and treating PC. Based on related studies, it has been found that the quercetin compound has significant effect on cancerous cell lines as well as animal models. Therefore, it can be used as a supplementary drug to treat a variety of cancers, particularly pancreatic cancer. This review is aimed at discussing the therapeutic effects of quercetin by targeting the molecular signaling pathway and identifying antigrowth, cell proliferation, antioxidative stress, EMT, induction of apoptotic, and autophagic features.The authors acknowledge the Molecular Medicine Research Center, Bio-Medicine Institute, Tabriz University of Medical Sciences, and the Clinical Research Development Unit of Sina Educational, Research and Treatment Center, Tabriz University of Medical Sciences, Tabriz, Iran. This work was supported and funded by Tabriz University of Medical Sciences, Tabriz, Iran (grant number: 68344)
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