Mapping the entrepreneurial university literature: A text mining approach

Since the introduction of the concept of entrepreneurial university in 1980’s, the number of studies has dramatically increased, in particular since 2015. This had made the literature on the entrepreneurial university complex, fragmented and difficult to navigate. This paper provides a comprehensive review of all topics covered in the body of literature on the entrepreneurial university and identifies the most salient topics and papers within this literature, making use of text-mining techniques. Our paper employs topic modelling that reveals the underlying semantic structure of texts to identify the different underlying. Our study systematically analyses 1,110 papers over the period 1983-2020 using the Latent Dirichlet Allocation algorithm. Our analysis shows that the entrepreneurial university is fragmented around different topics that are very diverse. We find a total of 20 differentiated topics. Our study suggests that topics related to the overarching theme of academic entrepreneurship, in particular to commercialisation of research and the triple helix model are very popular within the entrepreneurial university literature. Finally, our analysis reveals that case-study type of research is losing momentum, giving path to nascent topics of research in the areas of entrepreneurial capability and university-industry alliances, which are becoming very popular within the entrepreneurial university literature

Study on the vibration characteristics of the telescope T80 in the Javalambre astrophysical observatory (JAO) aimed at detecting invalid images

The location of large telescopes, generally far from the data processing centers, represents a logistical problem for the supervision of the capture of images. In this work, we carried out a preliminary study of the vibration signature of the T80 telescope at the Javalambre Astrophysical Observatory (JAO). The study analyzed the process of calculating the displacement that occurs because of the vibration in each of the frequencies in the range of interest. We analyzed the problems associated with very low frequencies by means of simulation, finding the most critical vibrations below 20 Hz, since they are the ones that generate greater displacements. The work also relates previous studies based on simulation with the real measurements of the vibration of the telescope taken remotely when it is subjected to different positioning movements (right ascension and/or declination) or when it performs movement actions such as those related to filter trays or mirror cover. The obtained results allow us to design a remote alarm system to detect invalid images (taken with excess vibration)

Modified filtered-x hierarchical lms algorithm with sequential partial updates for active noise control

In the field of active noise control (ANC), a popular method is the modified filtered-x LMS algorithm. However, it has two drawbacks: Its computational complexity higher than that of the conventional FxLMS, and its convergence rate that could still be improved. Therefore, we propose an adaptive strategy which aims at speeding up the convergence rate of an ANC system dealing with periodic disturbances. This algorithm consists in combining the organization of the filter weights in a hierarchy of subfilters of shorter length and their sequential partial updates (PU). Our contribution is threefold: (1) we provide the theoretical basis of the existence of a frequency-depend-ent parameter, called gain in step-size. (2) The theoretical upper bound of the step-size is compared with the limit obtained from simulations. (3) Additional experiments show that this strategy results in a fast algorithm with a computational complexity close to that of the conventional FxLMS

Transcriptomic dataset for Sardina pilchardus: Assembly, annotation, and expression of nine tissues.

[EN]European sardine or pilchard is a planktonic small pelagic fish present from the North Sea in Europe to the coast of Senegal in the North of Africa, and across the Mediterranean sea to the Black Sea. Ecologically, sardines are an intermediary link in the trophic network, preying on plankton and being predated by larger fishes, marine mammals, and seabirds. This species is of great nutritional and economic value as a cheap but rich source of protein and fat. It is either consumed directly by humans or fed as fishmeal for aquaculture and farm animals. Despite its importance in the food basket, little is known about the molecular mechanisms involved in protein and lipid synthesis in this species. We collected nine tissues of Sardina pilchardus and reconstructed the transcriptome. In all, 198,597 transcripts were obtained, from which 68,031 are protein-coding. Quality assessment of the transcriptome was performed by back-mapping reads to the transcriptome and by searching for Single Copy Orthologs. Additionally, Gene Ontology and KEGG annotations were retrieved for most of the protein-coding genes. Finally, each library was quantified in terms of Transcripts per Million to disclose their expression patterns.We gratefully acknowledge funding from the Basque Government through a predoctoral grant (PRE_2017_2_0169) and from the Basque University System research group IT1233-19, “Applied Genomics and Bioinformatics”. We also acknowledge funding from the IFREMER institute and by FFP (France Filière Pêche) through the project CAPTAIN

The role of NPOs and international actors in the national innovation system: A network-based approach

This paper conducts an explorative analysis of the UK's nanotechnology research collaboration network to understand the contributions of the different institutions in the development and generation of knowledge. Framed in the National Innovation System (NIS) and the Triple Helix (TH) model literature, this paper makes use of social network analysis (SNA) tools to identify the role and involvement of different institutional actors in the interactions and collaborations within the nanotechnology network. Building on the traditional university–industry–government three-helix interaction model, our paper includes two extra dimensions in the model to account for the increase in international collaboration and the increasingly important role of non-profit organizations (NPOs) in knowledge generation. In this way, our paper responds to recent calls to adapt the traditional NIS models to reflect the new realities of scientific collaboration

A Novel Transcriptome-Derived SNPs Array for Tench (Tinca Tinca L.)

Tench (Tinca tinca L.) has great economic potential due to its high rate of fecundity and long-life span. Population genetic studies based on allozymes, microsatellites, PCR-RFLP and sequence analysis of genes and DNA fragments have revealed the presence of Eastern and Western phylogroups. However, the lack of genomic resources for this species has complicated the development of genetic markers. In this study, the tench transcriptome and genome were sequenced by high-throughput sequencing. A total of 60,414 putative SNPs were identified in the tench transcriptome using a computational pipeline. A set of 96 SNPs was selected for validation and a total of 92 SNPs was validated, resulting in the highest conversion and validation rate for a non-model species obtained to date (95.83%). The validated SNPs were used to genotype 140 individuals belonging to two tench breeds (Tabor and Hungarian), showing low (F-ST = 0.0450) but significant (<0.0001) genetic differentiation between the two tench breeds. This implies that set of validated SNPs array can be used to distinguish the tench breeds and that it might be useful for studying a range of associations between DNA sequence and traits of importance. These genomic resources created for the tench will provide insight into population genetics, conservation fish stock management, and aquaculture.This research was supported by projects CENAKVA and Reproductive and genetic approaches for fish biodiversity conservation and aquaculture (CZ02.1.01/0.0/0.0/16_025/0007370) funded by Ministry of Education, Youth and Sports of the Czech Republic, and by the Genomic Resources Research Group from the Basque University System (IT558-10) funded by the Department of Education, Universities and Research of the Basque Government. JL is supported by the pre-doctoral program Education Department of the Basque Government. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Phenotypic Differences in a PRPH2 Mutation in Members of the Same Family Assessed with OCT and OCTA

Choroidal dystrophies comprise a group of chorioretinal degenerations. However, the different findings observed among these patients make it difficult to establish a correct clinical diagnosis. The objective of this study was to characterize new clinical findings by optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) in these patients. Four family members with a PRPH2 gene mutation (p.Arg195Leu) were included. OCT was performed at the macula, and the thickness of the outer and inner retina, total retina, and choroid was measured. The features of the vascular network were analyzed by OCTA. Patients showed a decreased outer nuclear layer in the avascular area compared with the controls. Two patients presented greater foveal and parafoveal degeneration of the outer retina, whereas the most degenerated area in the rest was the perifovea. Disruption of the third outer band at the foveola is one of the first-altered outer bands. Slow blood flow areas or capillary dropout were main signs in the deep capillary plexus. Microaneurysms were frequently observed in less degenerated retinas. Vascular loops and intraretinal microvascular abnormalities (IRMAs) were present in the superficial plexus. Extensive degeneration of the choriocapillaris was detected. Phenotypic differences were found between patients: two showed central areolar choroidal dystrophy and the rest had extensive chorioretinal atrophy. These signs observed in OCT and OCTA can help to more appropriately define the clinical disease in patients with choroidal dystrophies.This research was funded by grants from the Spanish Ministry of Science and Innovation (FEDER- PID2019-106230RB-I00, RD16/0008/0001), Spanish Ministry of Universities (FPU16/04114 and FPU18/02964), Instituto de Salud Carlos III (RETICS-FEDER RD16/0008/0016), Asociación Retina Asturias/Cantabria, FARPE-FUNDALUCE, and Generalitat Valenciana (IDIFEDER/2017/064)

Mapping the entrepreneurial university literature: a text mining approach

Since the introduction of the concept of entrepreneurial university in 1980s, the number of studies has dramatically increased, in particular since 2015. This had made the literature on the entrepreneurial university complex, fragmented and difficult to navigate. This paper provides a comprehensive review of all topics covered in the body of literature on the entrepreneurial university and identifies the most salient topics and papers within this literature, making use of text-mining techniques. Our paper employs topic modelling that reveals the underlying semantic structure of texts to identify the different underlying. Our study systematically analyses 1,110 papers over the period 1983–2020 using the Latent Dirichlet Allocation algorithm. Our analysis shows that the entrepreneurial university is fragmented around different topics that are very diverse. We find a total of 20 differentiated topics. Our study suggests that topics related to the overarching theme of academic entrepreneurship, in particular to commercialisation of research and the triple helix model are very popular within the entrepreneurial university literature. Finally, our analysis reveals that case-study type of research is losing momentum, giving path to nascent topics of research in the areas of entrepreneurial capability and university-industry alliances, which are becoming very popular within the entrepreneurial university literature

Neuraminidase Antibodies and H5N1: Geographic-Dependent Influenza Epidemiology Could Determine Cross-Protection against Emerging Strains

Correspondencepublished_or_final_versio

Criptococosis pulmonar que simula un cáncer de pulmón

Cryptococcosis; Pulmonary malignancyCriptococcosi; Càncer de pulmóCriptococosis; Cáncer de pulmó