Seasonal temperature trends on the Spanish mainland: A secular study (1916–2015)

Trends in seasonal mean values of maximum and minimum temperature are analysed in the Spanish mainland from the new MOTEDAS_century database. This new data set has been developed combining the digitalized archives from the Spanish Meteorological Agency (AEMET) with information retrieved from Annual Books published by the former Meteorological Agency dating back to 1916, and covers the period 1916–2015. In all four seasons, mean seasonal temperature of maximum (Tmax) and minimum (Tmin) increased. The raising occurred in two main pulses separated by a first pause around the middle of the 20th century, but differed among seasons and also between maximum and minimum temperature. Analysis of the percentage of land affected by significant trends in maximum temperature reveals two increasing phases in spring and summer for Tmax, and in spring, summer, and autumn for Tmin. However, winter Tmax only rose during the recent decades, and autumn Tmax in the first decades. Negative significant trends were found in extended areas in spring Tmax, and in spring, autumn, and summer Tmin, confirming the first pause around the 1940's–1960's. Trends of seasonal mean values of Tmax and Tmin are not significant for at least the last 25–35 years of the study period, depending on the season. The areas under significant positive trend are usually more extended for Tmin than Tmax at any season and period. Areas with significant trend expand and contract in time according to two spatial gradients: south-east to north-west (east-west) for Tmax, and west to east for Tmin. We hypothesize a relationship between atmospheric prevalent advection and relief as triggering factors to understand spatial and temporal differences in seasonal temperatures at regional scale during the 20th century in the Iberian Peninsula

The consecutive disparity of precipitation in conterminous Spain

Precipitation irregularity constitutes a constraint for natural systems and socio-economic activities, particularly in water-scarce environments. Standard variability statistics such as the standard deviation, variance, and coefficient of variation do not consider the chronological order of these values. In Climatology, however, the temporal order of meteorological events is a relevant factor that can affect natural and socio-economic systems. In order to evaluate the disparity between consecutive values in precipitation series, we applied the Consecutive Disparity Index (D) to the monthly grid with the highest spatial resolution (10×10 km) existing in Peninsular Spain for the period December 1915–November 2015. Monthly, seasonal, and annual D values show an increase from north to southwest, especially in July and August. The D values for the month-to-month correlative series and for monthly mean precipitation reveal a relatively similar pattern. In the latter case, however, the low values are recorded towards southern Spain, following some mountain ranges in the Centre-East of the territory. Monthly, seasonal, and annual precipitation values are also negatively correlated with the corresponding D values. © 2021, The Author(s)

Shortfalls and Solutions for Meeting National and Global Conservation Area Targets

Governments have committed to conserving greater than or equal to 17% of terrestrial and greater than or equal to 10% of marine environments globally, especially areas of particular importance for biodiversity through ecologically representative Protected Area (PA) systems or other area-based conservation measures , while individual countries have committed to conserve 3-50% of their land area. We estimate that PAs currently cover 14.6% of terrestrial and 2.8% of marine extent, but 59-68% of ecoregions, 77-78% of important sites for biodiversity, and 57% of 25,380 species have inadequate coverage. The existing 19.7 million km super(2) terrestrial PA network needs only 3.3 million km super(2) to be added to achieve 17% terrestrial coverage. However, it would require nearly doubling to achieve, cost-efficiently, coverage targets for all countries, ecoregions, important sites, and species. Poorer countries have the largest relative shortfalls. Such extensive and rapid expansion of formal PAs is unlikely to be achievable. Greater focus is therefore needed on alternative approaches, including community- and privately managed sites and other effective area-based conservation measures

Incidencias en Trichostrongylídeos en relación con los patrones de remolinos frontales en bovinos

La transmisión de los nematodes gastrointestinales trichostrongylideos de los rumiantes en pastoreo está asociada con la ingestión de sus larvas infectivas distribuidas en las pasturas. Con el objetivo de analizar si la incidencia de estas parasitosis en bovinos podría estar influenciada por la posición de los remolinos pilosos de la cabeza, fueron evaluadas las intensidades medias e Intervalos de confianza 95 % de los recuentos de huevos de nematodes por gramo de materia fecal (hpg) de 126 muestras pertenecientes a tres rodeos de bovinos Aberdeen Angus de 8 a 10 meses de edad. Los valores hallados para los animales con remolinos-altos fueron de 203.7 (155.6-259.3), 300.1 (200-440.1) y 360 (200-520), para animales con los remolinos-medios de 253.4 (173.3-360.1), 417 (216.6-600.7) y 416.7 (341.67-500) y para los animales con remolinos-bajos de 250 (186.4-318.2), 362.8 (212.5-525.5) y 433.6 (350.06-522.6) en los rodeos denominados Villegas, Zavalla y Tierra. En los tres rodeos, los bovinos con remolinos medios y bajos presentaron tendencias mayores en sus incidencias medias, mientras que en los animales con remolinos pilosos altos, las incidencias medias tendieron a ser más bajas. Otros factores, además del comportamiento, pueden influir en las intensidades del parasitismo por nematodes trichostrongylideos según los tipos de remolinos. Entender las diferencias probablemente esté asociado a explicar cómo se conforma el estilo de pastoreo en los grupos de animales en relación a cada subtipo en la zona de ingesta.Transmission of gastrointestinal nematodes from grazing ruminants is associated with the ingestion of their infective larvae distributed in pastures. In order to analyze if the incidence of parasitism in cattle could be influenced by associated to hair whorl position of the head, the mean intensities and 95% confidence intervals of nematode egg counts were evaluated by gram of fecal material (epg) of 126 samples cattle of 8 to 10 months old in three ranchs of Aberdeen Angus. The values were for animals with high whorl 203.7 (155.6-259.3), 300.1 (200-440.1) and 360 (200-520), for animals with middle whorl 253.4 (173.3-360.1), 417 (216.6)-600.7) and 416.7 (341.67-500), and for animals with low whorl 250 (186.4-318.2), 362.8 (212.5-525.5) and 433.6 (350.06-522.6) in the herds Villegas, Zavalla and Tierra. In the three rodeos, the animals with medium and low whorl presented higher trends in their mean incidences, while in animals with high hair whorl, the average incidences tended to be lower. Other factors, besides behavior, can influence the intensities of parasitism by trichostrongylid nematodes according to the types of swirls. Understanding the differences is probably associated with explaining how the grazing style is conformed in the groups of animals in relation to each subtype in the intake zone.EEA General VillegasFil: Ardusso, Gerardo L. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; ArgentinaFil: Lacovara, Martin Andres. Becario INTA-AUDEAS CONADEV; ArgentinaFil: Graziati, Georgina. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; ArgentinaFil: Angulo Lewille, M. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; ArgentinaFil: Kleinerman, Gabriela. The Hebrew University of Jerusalem. Koret School of Veterinary Medicine; IsraelFil: Buffarini, Miguel. Instituto Nacional de Tecnología Agropecuaria (INTA). Estación Experimental Agropecuaria General Villegas; ArgentinaFil: Giudici, Claudio. Universidad Nacional de Rosario. Facultad de Ciencias Veterinarias; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Luminous Red Galaxy Clustering at z~0.7 - First Results using AAOmega

We report on the AAT-AAOmega LRG Pilot observing run to establish the feasibility of a large spectroscopic survey using the new AAOmega instrument. We have selected Luminous Red Galaxies (LRGs) using single epoch SDSS riz-photometry to i<20.5 and z<20.2. We have observed in 3 fields including the COSMOS field and the COMBO-17 S11 field, obtaining a sample of ~600 redshift z>=0.5 LRGs. Exposure times varied from 1 - 4 hours to determine the minimum exposure for AAOmega to make an essentially complete LRG redshift survey in average conditions. We show that LRG redshifts to i<20.5 can measured in approximately 1.5hr exposures and present comparisons with 2SLAQ and COMBO-17 (photo-)redshifts. Crucially, the riz selection coupled with the 3-4 times improved AAOmega throughput is shown to extend the LRG mean redshift from z=0.55 for 2SLAQ to z=0.681+/- 0.005 for riz-selected LRGs. This extended range is vital for maximising the S/N for the detection of the baryon acoustic oscillations (BAOs). Furthermore, we show that the amplitude of LRG clustering is s_0 = 9.9+/-0.7 h^-1 Mpc, as high as that seen in the 2SLAQ LRG Survey. Consistent results for the real-space amplitude are found from projected and semi-projected correlation functions. This high clustering amplitude is consistent with a long-lived population whose bias evolves as predicted by a simple ``high-peaks'' model. We conclude that a redshift survey of 360 000 LRGs over 3000deg^2, with an effective volume some 4 times bigger than previously used to detect BAO with LRGs, is possible with AAOmega in 170 nights.Comment: 12 pages, 7 figures, 8 tables, minor changes, matches published versio

Ginsenosides act as positive modulators of P2X4 receptors

We investigated the selectivity of protopanaxadiol ginsenosides from Panax ginseng acting as positive allosteric modulators on P2X receptors. ATP-induced responses were measured in stable cell lines overexpressing human P2X4 using a YOPRO-1 dye uptake assay, intracellular calcium measurements, and whole-cell patch-clamp recordings. Ginsenosides CK and Rd were demonstrated to enhance ATP responses at P2X4 by ∼twofold, similar to potentiation by the known positive modulator ivermectin. Investigations into the role of P2X4 in mediating a cytotoxic effect showed that only P2X7 expression in HEK-293 cells induces cell death in response to high concentrations of ATP, and that ginsenosides can enhance this process. Generation of a P2X7-deficient clone of BV-2 microglial cells using CRISPR/ Cas9 gene editing enabled an investigation of endogenous P2X4 in a microglial cell line. Compared with parental BV-2 cells, P2X7-deficient BV-2 cells showed minor potentiation of ATP responses by ginsenosides, and insensitivity to ATP 2 or ATP 1 ginsenoside-induced cell death, indicating a primary role for P2X7 receptors in both of these effects. Computational docking to a homology model of human P2X4, based on the open state of zfP2X4, yielded evidence of a putative ginsenoside binding site in P2X4 in the central vestibule region of the large ectodomain

Kerr effect in structured superluminal media

A comprehensive overview is presented about optical fiber-based tunable photonic delay lines, which have been steadily developed over the last decade for the realization of all-optically controlled timing functions. The most widely used techniques, such as those based on slow & fast light and wavelength conversion associated to dispersion, are described and their physical limitations are discussed in terms of the maximal achievable delay, the associated signal distortion and signal bandwidth. Besides, an entirely different approach for all-optical signal delaying is introduced. This technique is based on movable grating reflectors dynamically generated in highly birefringent optical fibers. This type of delay line has experimentally demonstrated large tunable delaying with a moderate signal distortion for high capacity optical data streams and even for wideband analog signals

Dark Patterns after the GDPR: Scraping Consent Pop-ups and Demonstrating their Influence

New consent management platforms (CMPs) have been introduced to the web to conform with the EU's General Data Protection Regulation, particularly its requirements for consent when companies collect and process users' personal data. This work analyses how the most prevalent CMP designs affect people's consent choices. We scraped the designs of the five most popular CMPs on the top 10,000 websites in the UK (n=680). We found that dark patterns and implied consent are ubiquitous; only 11.8% meet the minimal requirements that we set based on European law. Second, we conducted a field experiment with 40 participants to investigate how the eight most common designs affect consent choices. We found that notification style (banner or barrier) has no effect; removing the opt-out button from the first page increases consent by 22--23 percentage points; and providing more granular controls on the first page decreases consent by 8--20 percentage points. This study provides an empirical basis for the necessary regulatory action to enforce the GDPR, in particular the possibility of focusing on the centralised, third-party CMP services as an effective way to increase compliance.Comment: 13 pages, 3 figures. To appear in the Proceedings of CHI '20 CHI Conference on Human Factors in Computing Systems, April 25--30, 2020, Honolulu, HI, US

Casein SNP in Norwegian goats: additive and dominance effects on milk composition and quality

<p>Abstract</p> <p>Background</p> <p>The four casein proteins in goat milk are encoded by four closely linked casein loci (<it>CSN1S1</it>, <it>CSN2</it>, <it>CSN1S2 </it>and <it>CSN3</it>) within 250 kb on caprine chromosome 6. A deletion in exon 12 of <it>CSN1S1</it>, so far reported only in Norwegian goats, has been found at high frequency (0.73). Such a high frequency is difficult to explain because the national breeding goal selects against the variant's effect.</p> <p>Methods</p> <p>In this study, 575 goats were genotyped for 38 Single Nucleotide Polymorphisms (SNP) located within the four casein genes. Milk production records of these goats were obtained from the Norwegian Dairy Goat Control. Test-day mixed models with additive and dominance fixed effects of single SNP were fitted in a model including polygenic effects.</p> <p>Results</p> <p>Significant additive effects of single SNP within <it>CSN1S1 </it>and <it>CSN3 </it>were found for fat % and protein %, milk yield and milk taste. The allele with the deletion showed additive and dominance effects on protein % and fat %, and overdominance effects on milk quantity (kg) and lactose %. At its current frequency, the observed dominance (overdominance) effects of the deletion allele reduced its substitution effect (and additive genetic variance available for selection) in the population substantially.</p> <p>Conclusions</p> <p>The selection pressure of conventional breeding on the allele with the deletion is limited due to the observed dominance (overdominance) effects. Inclusion of molecular information in the national breeding scheme will reduce the frequency of this deletion in the population.</p