21 research outputs found

    Theatre graphics and graphic theatre : Zich's semantics in posters and publicity

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    The essay employs the concept of the 'semantic image' as articulated by Czech aesthetician Otakar Zich in his book The Aesthetics of Dramatic Art in order to outline how theatre publicity relates to theatre production and performance. Theatre graphics, posters, and other promotional materials contain images that substitute or compensate for what is not to be seen and heard onstage in form of 'technical images'; thus, these graphics condition the 'representational images' of dramatic locations.1 Publicity images can be also used to manipulate imagery associations related to actors as well as dramatic characters in order to facilitate their desired reception. This article focuses on the posters produced for Prague's National Theatre opera production of Tramvestie (2019) and two stagings of Peter Shaffer's Equus (1973, 2007) along with Alphonse Mucha's posters for Sarah Bernhardt

    Direct Probing of Dispersion Quality of ZrO2 Nanoparticles Coated by Polyelectrolyte at Different Concentrated Suspensions.

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    This study reports useful application of the electrokinetic sonic amplitude (ESA) technique in combination with rheometry and electron microscopy techniques for direct probing the stability of low and high-concentrated zirconia (ZrO2) nanosuspensions in the presence of an alkali-free anionic polyelectrolyte dispersant Dolapix CE64. A comparative study of the electrokinetic characteristics and the rheological behavior of concentrated ZrO2 nanosuspensions has been done. Good agreement was obtained from relationship between the electrokinetic characteristics (zeta potential, ESA signal), viscosity, and its pH dependence for each concentrated ZrO2 nanosuspension with different dispersant concentration in the range of 0.9-1.5 mass%. A nanoscale colloidal hypothesis is proposed to illustrate that the addition of different amounts of dispersant influences on both the stability and the electrokinetic and rheological properties of concentrated ZrO2 nanosuspensions. It is found that an optimum amount of 1.4 mass% dispersant at the inherent pH (>9.2) can be attached fully onto the nanoparticles with sufficient electrosteric dispersion effects, suitable for casting applications. Supplementary scanning electron microscopy (SEM) and high-resolution transmission electron microscopy (HR-TEM) analyses followed by colorization effect were taken to verify the visible interaction between dispersant and nanoparticles surfaces. SEM and HR-TEM images proved the existence of visible coverage of dispersant on the surface of individual nanoparticles and showed that thin polyelectrolyte layers were physically bound onto the particles' surfaces. This study will be of interest to materials scientists and engineers who are dealing with dispersion technology, nanoparticle surface treatments, functionalization, characterization, and application of bio/nanoparticle suspensions at various concentrations using different types of polymers

    Mixed-hybrid model of the fracture flow

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    . Finite element/mixed-hybrid formulation of a discrete fracture network model. Key words. fracture flow, stochastic discrete fracture network, mixed-hybrid formulation of the finite element method 1. Introduction. Nuclear energy produced on the Earth has reached 16% of the world's energy production and it is generated by almost 500 nuclear reactors. The weakest link in the production of the energy by this way is a safe storage of highly radioactive spent fuel. This text deals with suggestion of a mathematical model describing percolation of groundwater in the fractured matrix of a solid rock, medium supposed as possible repository of dangerous nuclear waste. In general, there are three main possible accesses to the problem of modelling the fracture flow. When only a large-scale model is required and if there is no need to know detail flow and transport behavior in any site subarea, it is possible to use equivalent porous medium models. More complex than single continuum models are ..

    Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II—Design, Synthesis, and Evaluation

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    Kynurenic acid is a neuroprotective metabolite of tryptophan formed by kynurenine aminotransferase (KAT) catalyzed transformation of kynurenine. However, its high brain levels are associated with cognitive deficit and with the pathophysiology of schizophrenia. Although several classes of KAT inhibitors have been published, the search for new inhibitor chemotypes is crucial for the process of finding suitable clinical candidates. Therefore, we used pharmacophore modeling and molecular docking, which predicted derivatives of heterocyclic amino ketones as new potential irreversible inhibitors of kynurenine aminotransferase II. Thiazole and triazole-based amino ketones were synthesized within a SAR study and their inhibitory activities were evaluated in vitro. The observed activities confirmed our computational model and, moreover, the best compounds showed sub-micromolar inhibitory activity with 2-alaninoyl-5-(4-fluorophenyl)thiazole having IC50 = 0.097 µM
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