ScanGAN360: a generative model of realistic scanpaths for 360 images

Understanding and modeling the dynamics of human gaze behavior in 360° environments is crucial for creating, improving, and developing emerging virtual reality applications. However, recruiting human observers and acquiring enough data to analyze their behavior when exploring virtual environments requires complex hardware and software setups, and can be time-consuming. Being able to generate virtual observers can help overcome this limitation, and thus stands as an open problem in this medium. Particularly, generative adversarial approaches could alleviate this challenge by generating a large number of scanpaths that reproduce human behavior when observing new scenes, essentially mimicking virtual observers. However, existing methods for scanpath generation do not adequately predict realistic scanpaths for 360° images. We present ScanGAN360, a new generative adversarial approach to address this problem. We propose a novel loss function based on dynamic time warping and tailor our network to the specifics of 360° images. The quality of our generated scanpaths outperforms competing approaches by a large margin, and is almost on par with the human baseline. ScanGAN360 allows fast simulation of large numbers of virtual observers, whose behavior mimics real users, enabling a better understanding of gaze behavior, facilitating experimentation, and aiding novel applications in virtual reality and beyond

El paleógeno del sector suroccidental de la Cuenca del Duero: nueva división estratigráfica y controles sobre su sedimentación

A Paleogene four-fold stratigraphical division is proposed here as result from the detailed studies carried out during the elaboration of 22 sheets of the Geological Map of Spain (E. 1:50.000). This units (T.S.U.) are limited by regional discordances and they have a Upper Cretaceous to Oligocene ages. The previous stratigraphical schemes are rearranged due to the different stratigraphicalrelations observed between the lithostratigraphical units proPosed by other workers (Jiménez, 1970; Corrochano, 1977; Alonso, 1981 ...). An Upper Cretaceous-Paleocene age is assumed to T.S.U. MC which is mainly composed by siliciclastic sediments strongly silicified forming a FU megasequence. It is interpretated as braided streams that flowed downslope filling paleovalleys eroded onto Paleozoic materials. Mineralogical features point to a tropical climate. Lower Eocene (T.S.U. P1) is identified in the Salamanca area, where it was considered as lacking. It is composed by arkosic sediments forming a CU megasequence. Fossil faunas of this T.S.U. record a subtropical climate. It is observed a transition from high sinuosity streams to braided ones. T.S.U. P2 (Middle Eocene-Lower Oligocene) is composed of two lithostratigraphical units previously considered as bounded by a discordance (Alonso, 198 1). It has a subarkosic to lithic nature and forms a CU megasequence. This unit records a subtropical climate with short arid periods and is interpretated as braided streams showing an increasing stability and enviromental energy to the top. T.S.U. P3 (Upper Oligocene) is composed by arkosic sediments previously considered of Vallesian (Middle to Upper Miocene) age. They form a CU megasequence that records braided streams prograding basin ward from higher areas. Palinological associations and pedological features indicate an arid mediterranean climate with long arid periods and a short rainy season with strong floods. We consider that most of Lower Miocene sediments are of Paleogene age. They are afected by a widespread alteration profile developed along Lower Miocene that masked its more significative features. Sedimentological analysis of T.S.U. shows that its megasequentiality is related to the rates of tectonical uplift of source areas whereas a distensive regime developed in the sedimentation basin

Multimodality in {VR}: {A} Survey

Virtual reality has the potential to change the way we create and consume content in our everyday life. Entertainment, training, design and manufacturing, communication, or advertising are all applications that already benefit from this new medium reaching consumer level. VR is inherently different from traditional media: it offers a more immersive experience, and has the ability to elicit a sense of presence through the place and plausibility illusions. It also gives the user unprecedented capabilities to explore their environment, in contrast with traditional media. In VR, like in the real world, users integrate the multimodal sensory information they receive to create a unified perception of the virtual world. Therefore, the sensory cues that are available in a virtual environment can be leveraged to enhance the final experience. This may include increasing realism, or the sense of presence; predicting or guiding the attention of the user through the experience; or increasing their performance if the experience involves the completion of certain tasks. In this state-of-the-art report, we survey the body of work addressing multimodality in virtual reality, its role and benefits in the final user experience. The works here reviewed thus encompass several fields of research, including computer graphics, human computer interaction, or psychology and perception. Additionally, we give an overview of different applications that leverage multimodal input in areas such as medicine, training and education, or entertainment; we include works in which the integration of multiple sensory information yields significant improvements, demonstrating how multimodality can play a fundamental role in the way VR systems are designed, and VR experiences created and consumed

The METOP-A Orbit Acquisition Strategy and its LEOP Operational Experience

Europe's first polar-orbiting weather satellite, METOPA, was launched by a Soyuz launcher from Baikonur Cosmodrome on the 19th of October of 2006. The routine operations of METOP-A are conducted by EUMETSAT (European Organization for Exploitation of Meteorological Satellites) in the frame of the European Polar System mission (EPS). The METOP-A Launch and Early Orbit Phase (LEOP) operations have been performed by ESA/ESOC. The Flight Dynamics Orbit Determination and Control team (OD&C) at ESOC was in charge of correcting the S/C orbit as delivered by the launcher in such a way that EUMETSAT would be able to acquire the reference orbit with a drift-stop manoeuvre approximately two weeks after a LEOP of 3 days and Hand-Over to the EUMETSAT Control Centre (EUMETSAT-CC) in Darmstadt, Germany. The various strict constraints and the short amount of time available for ESOC operations made this task challenging. Several strategies were prepared before launch and analysed during LEOP based on the achieved injection orbit. This paper presents the different manoeuvre strategies investigated and finally applied to acquire the operational orbit, reporting as well the details of its execution and final achieved state

Networks of strong ties

Social networks transmitting covert or sensitive information cannot use all ties for this purpose. Rather, they can only use a subset of ties that are strong enough to be ``trusted''. In this paper we consider transitivity as evidence of strong ties, requiring that each tie can only be used if the individuals on either end also share at least one other contact in common. We examine the effect of removing all non-transitive ties in two real social network data sets. We observe that although some individuals become disconnected, a giant connected component remains, with an average shortest path only slightly longer than that of the original network. We also evaluate the cost of forming transitive ties by deriving the conditions for the emergence and the size of the giant component in a random graph composed entirely of closed triads and the equivalent Erdos-Renyi random graph.Comment: 10 pages, 7 figure

Properties of Healthcare Teaming Networks as a Function of Network Construction Algorithms

Network models of healthcare systems can be used to examine how providers collaborate, communicate, refer patients to each other. Most healthcare service network models have been constructed from patient claims data, using billing claims to link patients with providers. The data sets can be quite large, making standard methods for network construction computationally challenging and thus requiring the use of alternate construction algorithms. While these alternate methods have seen increasing use in generating healthcare networks, there is little to no literature comparing the differences in the structural properties of the generated networks. To address this issue, we compared the properties of healthcare networks constructed using different algorithms and the 2013 Medicare Part B outpatient claims data. Three different algorithms were compared: binning, sliding frame, and trace-route. Unipartite networks linking either providers or healthcare organizations by shared patients were built using each method. We found that each algorithm produced networks with substantially different topological properties. Provider networks adhered to a power law, and organization networks to a power law with exponential cutoff. Censoring networks to exclude edges with less than 11 shared patients, a common de-identification practice for healthcare network data, markedly reduced edge numbers and greatly altered measures of vertex prominence such as the betweenness centrality. We identified patterns in the distance patients travel between network providers, and most strikingly between providers in the Northeast United States and Florida. We conclude that the choice of network construction algorithm is critical for healthcare network analysis, and discuss the implications for selecting the algorithm best suited to the type of analysis to be performed.Comment: With links to comprehensive, high resolution figures and networks via figshare.co

Disk galaxies with broken luminosity profiles from cosmological simulations

We present SPH cosmological simulations of the formation of three disk galaxies with a detailed treatment of chemical evolution and cooling. The resulting galaxies have properties compatible with observations: relatively high disk-to-total ratios, thin stellar disks and good agreement with the Tully-Fisher and the luminosity-size relations. They present a break in the luminosity profile at 3.0 +- 0.5 disk scale lengths, while showing an exponential mass profile without any apparent breaks, in line with recent observational results. Since the stellar mass profile is exponential, only differences in the stellar populations can be the cause of the luminosity break. Although we find a cutoff for the star formation rate imposed by a density threshold in our star formation model, it does not coincide with the luminosity break and is located at 4.3 +- 0.4 disk scale lengths, with star formation going on between both radii. The color profiles and the age profiles are "U-shaped", with the minimum for both profiles located approximately at the break radius. The SFR to stellar mass ratio increases until the break, explaining the coincidence of the break with the minimum of the age profile. Beyond the break we find a steep decline in the gas density and, consequently, a decline in the SFR and redder colors. We show that most stars (64-78%) in the outer disk originate in the inner disk and afterwards migrate there. Such stellar migrations are likely the main origin of the U-shaped age profile and, therefore, of the luminosity break.Comment: 8 pages, 4 figures. Accepted by ApJ

Reticulocyte Maturation Parameters Are Reliable Early Predictors of Hematopoietic Engraftment after Allogeneic Stem Cell Transplantation

AbstractEarly detection of donor-derived hematopoietic restoration after allogeneic stem cell transplantation (allo-SCT) is a crucial issue in the management of heavily immunocompromised patients. The aim of this prospective study was to validate our previously defined cutoff values for reticulocyte maturation parameters as early predictors of hematopoietic engraftment. Importantly, the effect of clinical variables in reticulocyte engraftment was also sought. For this purpose, we prospectively studied 136 consecutive patients undergoing allo-SCT from related (n = 89) or unrelated (n = 47) donors. High fluorescence reticulocytes (RETH), immature reticulocyte fraction (IRF), mean fluorescence index (MFI), and mean reticulocyte volume (MRV) were automatically measured in peripheral blood samples drawn on a daily basis. We previously defined reticulocyte engraftment when MFI ≥10, RETH ≥3%, IRF ≥10%, and MRV ≥110 fL. Median neutrophil engraftment was 18 days (range, 10-35 days); for reticulocyte parameters, the values were 14 days for IRF (range, 7-45 days), 14 days for MFI (range, 7-43 days), 15 days for RETH (range, 7-43 days), and 21 days for MRV (range, 9-74 days). These differences reached statistical significance for MFI and IRF when compared with standard neutrophil recovery, even when analyzing siblings or unrelated donors separately. In univariate analysis, donor-recipient ABO disparity adversely influenced erythroid engraftment (P = .04 for IRF, P = .03 for MFI), but the infusion of >2.9 × 106/kg of CD34+ cells was associated with a shorter time to reach erythroid engraftment (P = .02 for IRF and MFI). In Cox regression analysis, ≥100/μL neutrophils and IRF ≥10% were predictive parameters for standard neutrophil engraftment. Based on these findings, we suggest that serial measurement of IRF or MFI should be routinely used to trace hematopoietic restoration after allo-SCT because these preceded standard neutrophil recovery by a median of 4 days and are therefore very useful to make clinical decisions

Single Cord Blood Combined with HLA-Mismatched Third Party Donor Cells: Comparable Results to Matched Unrelated Donor Transplantation in High-Risk Patients with Hematologic Disorders

AbstractMatched unrelated donor (MUD) transplantation is the first alternative in the absence of a matched sibling donor. For patients without a suitable adult donor, we have adopted the dual stem cell transplantation protocol consisting of cord blood (CB) in combination with CD34+ cells from a third party HLA-mismatched donor. We analyzed the outcomes of patients undergoing both procedures in a single center. Starting in 2004, a total of 20 patients with high-risk disease underwent 22 dual transplants and 25 patients underwent myeloablative MUD transplantation. The 30-day cumulative incidence of neutrophil engraftment was similar in both groups (91% and 95%), with a median time to engraftment of 14 and 16 days, respectively. Grade II-IV acute graft-versus-host disease was more frequent in the MUD group (40% versus 5%). Except for a tendency toward a higher incidence of viral hemorrhagic cystitis in the dual transplantation group, posttransplantation infectious events were comparable in the 2 groups. The 3-year cumulative incidence rates of relapse (41% versus 44%) and nonrelapse mortality (30% versus 25%) were similar in the MUD and dual transplantation cohorts. Estimated 3-year overall survival and disease-free survival were 47% and 41%, respectively, with no survival advantage for either group. In our experience, dual transplantation offers survival rates comparable to those from myeloablative MUD transplantation with similar nonrelapse mortality rates