3,576 research outputs found
A Correlation Between the Eight Grade Students\u27 Participation in English Extracurricular Activities and Their Speaking Ability at SMPN 6 Pekanbaru
This research is aimed at investigating whether there is a correlation between between students\u27 participation in English Extracurricular at school and their speaking ability at SMPN 6 Pekanbaru. This research used simple random sampling. The researcher found that extracurricular activity can improve students\u27 speaking ability at school. The result showed that coefficient correlation between two variable is 0,84, which means there is positive correlation between two variables. The researcher suggests the English teachers to pay more attention on the other factor that influencing speaking ability, such as: extracurricular activit
Development of DTPA-amino acid conjugates for successful trivalent actinide-lanthanide separations
Perspectives on regular and support class placement and factors that contribute to success of inclusion for children with ASD
For young children with autism spectrum disorder (ASD) in regular schools, ASD specific service delivery options include regular class placement with itinerant consultative support and support class placement. This study provided an examination of levels of parent, teacher and principal satisfaction with both regular class placement (n = 39) and a satellite support class option (n=35), which provides a more gradual transition into regular class. Given that regular class placement was the ultimate goal for children enrolled in the study, factors that either facilitated or acted as barriers to successful inclusion were examined for those children currently in regular classes. There were relatively high levels of parent, teacher and principal satisfaction with both satellite support class and regular class placement for children with ASD, with higher levels of parental satisfaction with satellite support placement. Across all respondents, the most frequently identified facilitating factors were related to teaching practices and skills. In contrast, barriers identified were generally related to child characteristics. A number of suggestions for future research are offered
Climate change drives poleward increases and equatorward declines in marine species
Marine environments have increased in temperature by an average of 1°C since preindustrial (1850) times [1]. Given that species ranges are closely allied to physiological
thermal tolerances in marine organisms [2], it may therefore be expected that ocean warming would lead to abundance increases at poleward range edges, and abundance declines towards the equator [3]. Here we report a global analysis of abundance tends of 304 widely distributed marine species over the last century, across a range of taxonomic groups from phytoplankton to fish and marine mammals. Specifically, using a literature database we investigate the extent that the direction and strength of longterm species abundance changes depend on the sampled location within the latitudinal range of species. Our results show that abundance increases have been most prominent where sampling has taken place at the poleward edges of species ranges, while abundance declines have been most prominent where sampling has taken place at the equatorward edge of species ranges. These data provide evidence of omnipresent large-scale changes in abundance of marine species consistent with warming over the last century, and suggest that adaptation has not provided a buffer against the negative effects of warmer conditions at the equatorward extent of species ranges. On the basis of these results we suggest that projected sea temperature increases of up to 1.5°C over pre-industrial levels by 2050 [4] will continue to drive latitudinal abundance shifts in marine species, including those of importance for coastal livelihoods
Facilitators and Barriers to Inclusion of Students With Autism Spectrum Disorder: Parent, Teacher, and Principal Perspectives
The inclusion of students with autism spectrum disorder (ASD) is increasing, but there have been no longitudinal studies of included students in Australia. Interview data reported in this study concern primary school children with ASD enrolled in mainstream classes in South Australia and New South Wales, Australia. In order to examine perceived facilitators and barriers to inclusion, parents, teachers, and principals were asked to comment on the facilitators and barriers to inclusion relevant to each child. Data are reported about 60 students, comprising a total of 305 parent interviews, 208 teacher interviews, and 227 principal interviews collected at 6-monthly intervals over 3.5 years. The most commonly mentioned facilitator was teacher practices. The most commonly mentioned barrier was intrinsic student factors. Other factors not directly controllable by school staff, such as resource limitations, were also commonly identified by principals and teachers. Parents were more likely to mention school- or teacher-related barriers. Many of the current findings were consistent with previous studies but some differences were noted, including limited reporting of sensory issues and bullying as barriers. There was little change in the pattern of facilitators and barriers identified by respondents over time. A number of implications for practice and directions for future research are discussed
Reducing in-stent restenosis therapeutic manipulation of miRNA in vascular remodeling and inflammation
Background:
Drug-eluting stents reduce the incidence of in-stent restenosis, but they result in delayed arterial healing and are associated with a chronic inflammatory response and hypersensitivity reactions. Identifying novel interventions to enhance wound healing and reduce the inflammatory response may improve long-term clinical outcomes. Micro–ribonucleic acids (miRNAs) are noncoding small ribonucleic acids that play a prominent role in the initiation and resolution of inflammation after vascular injury.<p></p>
Objectives:
This study sought to identify miRNA regulation and function after implantation of bare-metal and drug-eluting stents.<p></p>
Methods:
Pig, mouse, and in vitro models were used to investigate the role of miRNA in in-stent restenosis.<p></p>
Results:
We documented a subset of inflammatory miRNAs activated after stenting in pigs, including the miR-21 stem loop miRNAs. Genetic ablation of the miR-21 stem loop attenuated neointimal formation in mice post-stenting. This occurred via enhanced levels of anti-inflammatory M2 macrophages coupled with an impaired sensitivity of smooth muscle cells to respond to vascular activation.<p></p>
Conclusions:
MiR-21 plays a prominent role in promoting vascular inflammation and remodeling after stent injury. MiRNA-mediated modulation of the inflammatory response post-stenting may have therapeutic potential to accelerate wound healing and enhance the clinical efficacy of stenting
Modified DTPA ligand systems for simplified trivalent actinide-lanthanide separations based on the TALSPEAK process
How do frontline staff use patient experience data for service improvement? Findings from an ethnographic case study evaluation
Funding Information: The authors would like to thank the following: the ward teams and senior management teams at the six participating case study sites. Neil Churchill, Angela Coulter, Ray Fitzpatrick, Crispin Jenkinson, Trish Greenhalgh and Sian Rees who were co-investigators on the study, contributing to the original design and conduct of the study. Esther Ainley and Steve Sizmur from Picker Institute Europe, who contributed to data collection and analysis. Prof. John Gabbay and Prof. Andr? le May, University of Southampton, for facilitating the learning community meetings. The members of the lay advisory panel: Barbara Bass, Tina Lonhgurst, Georgina McMasters, Carol Munt, Gillian Richards, Tracey Richards, Gordon Sturmey, Karen Swaffield, Ann Tomlime and Paul Whitehouse. The external members of the Study Steering Committee: Joanna Foster, Tony Berendt, Caroline Shuldham, Joanna Goodrich, Leigh Kendall, Bernard Gudgin and Manoj Mistry. At the time of conducting the research LL and SP were employed by the University of Oxford. Preliminary findings from the study have been presented publicly at the following conferences: European Association for Communication in Healthcare 2016; The International Society for Quality in Healthcare 2017; Health Services Research UK 2017; Medical Sociology 2018. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Publisher Copyright: © The Author(s) 2020. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Peer reviewedPublisher PD
Comorbid health conditions and their impact on social isolation, loneliness, quality of life, and well-being in people with dementia: longitudinal findings from the IDEAL programme
BackgroundMost people with dementia have multiple health conditions. This study explores (1) number and type of health condition(s) in people with dementia overall and in relation to age, sex, dementia type, and cognition; (2) change in number of health conditions over two years; and (3) whether over time the number of health conditions at baseline is related to social isolation, loneliness, quality of life, and/or well-being.MethodsLongitudinal data from the IDEAL (Improving the experience of Dementia and Enhancing Active Life) cohort were used. Participants comprised people with dementia (n = 1490) living in the community (at baseline) in Great Britain. Health conditions using the Charlson Comorbidity Index, cognition, social isolation, loneliness, quality of life, and well-being were assessed over two years. Mixed effects modelling was used.ResultsOn average participants had 1.8 health conditions at baseline, excluding dementia; increasing to 2.5 conditions over two years. Those with vascular dementia or mixed (Alzheimer’s and vascular) dementia had more health conditions than those with Alzheimer’s disease. People aged ≥ 80 had more health conditions than those aged < 65 years. At baseline having more health conditions was associated with increased loneliness, poorer quality of life, and poorer well-being, but was either minimally or not associated with cognition, sex, and social isolation. Number of health conditions had either minimal or no influence on these variables over time.ConclusionsPeople with dementia in IDEAL generally had multiple health conditions and those with more health conditions were lonelier, had poorer quality of life, and poorer well-being
Understanding how front-line staff use patient experience data for service improvement: an exploratory case study evaluation
Background and aim: The NHS collects a large number of data on patient experience, but there are
concerns that it does not use this information to improve care. This study explored whether or not and
how front-line staff use patient experience data for service improvement.
Methods: Phase 1 – secondary analysis of existing national survey data, and a new survey of NHS trust patient
experience leads. Phase 2 – case studies in six medical wards using ethnographic observations and interviews.
A baseline and a follow-up patient experience survey were conducted on each ward, supplemented by
in-depth interviews. Following an initial learning community to discuss approaches to learning from and
improving patient experience, teams developed and implemented their own interventions. Emerging findings
from the ethnographic research were shared formatively. Phase 3 – dissemination, including an online guide
for NHS staff.
Key findings: Phase 1 – an analysis of staff and inpatient survey results for all 153 acute trusts in England
was undertaken, and 57 completed surveys were obtained from patient experience leads. The most
commonly cited barrier to using patient experience data was a lack of staff time to examine the data
(75%), followed by cost (35%), lack of staff interest/support (21%) and too many data (21%). Trusts were
grouped in a matrix of high, medium and low performance across several indices to inform case study
selection. Phase 2 – in every site, staff undertook quality improvement projects using a range of data
sources. The number and scale of these varied, as did the extent to which they drew directly on patient
experience data, and the extent of involvement of patients. Before-and-after surveys of patient experience
showed little statistically significant change. Making sense of patient experience ‘data’ Staff were engaged
in a process of sense-making from a range of formal and informal sources of intelligence. Survey data
remain the most commonly recognised and used form of data. ‘Soft’ intelligence, such as patient stories,
informal comments and daily ward experiences of staff, patients and family, also fed into staff’s improvement plans, but they and the wider organisation may not recognise these as ‘data’. Staff may lack confidence in
using them for improvement. Staff could not always point to a specific source of patient experience ‘data’
that led to a particular project, and sometimes reported acting on what they felt they already knew needed
changing. Staff experience as a route to improving patient experience Some sites focused on staff motivation
and experience on the assumption that this would improve patient experience through indirect cultural and
attitudinal change, and by making staff feel empowered and supported. Staff participants identified several
potential interlinked mechanisms: (1) motivated staff provide better care, (2) staff who feel taken seriously
are more likely to be motivated, (3) involvement in quality improvement is itself motivating and (4) improving
patient experience can directly improve staff experience. ‘Team-based capital’ in NHS settings We propose
‘team-based capital’ in NHS settings as a key mechanism between the contexts in our case studies and observed
outcomes. ‘Capital’ is the extent to which staff command varied practical, organisational and social resources
that enable them to set agendas, drive process and implement change. These include not just material or
economic resources, but also status, time, space, relational networks and influence. Teams involving a range of
clinical and non-clinical staff from multiple disciplines and levels of seniority could assemble a greater range of
capital; progress was generally greater when the team included individuals from the patient experience office.
Phase 3 – an online guide for NHS staff was produced in collaboration with The Point of Care Foundation.
Limitations: This was an ethnographic study of how and why NHS front-line staff do or do not use
patient experience data for quality improvement. It was not designed to demonstrate whether particular
types of patient experience data or quality improvement approaches are more effective than others.
Future research: Developing and testing interventions focused specifically on staff but with patient
experience as the outcome, with a health economics component. Studies focusing on the effect of team
composition and diversity on the impact and scope of patient-centred quality improvement. Research into
using unstructured feedback and soft intelligence
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