8 research outputs found

    Humanities in Predoctoral Dental Education: A Scoping Review

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153732/1/jddjde019126.pd

    Simulation‐Based Medical Emergencies Education for Dental Students: A Three‐Year Evaluation

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153561/1/jddjde019084.pd

    Safety of intravenous ferric carboxymaltose versus oral iron in patients with nondialysis-dependent CKD: an analysis of the 1-year FIND-CKD trial.

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    Background: The evidence base regarding the safety of intravenous (IV) iron therapy in patients with chronic kidney disease (CKD) is incomplete and largely based on small studies of relatively short duration. Methods: FIND-CKD (ClinicalTrials.gov number NCT00994318) was a 1-year, open-label, multicenter, prospective study of patients with nondialysis-dependent CKD, anemia and iron deficiency randomized (1:1:2) to IV ferric carboxymaltose (FCM), targeting higher (400-600 ”g/L) or lower (100-200 ”g/L) ferritin, or oral iron. A post hoc analysis of adverse event rates per 100 patient-years was performed to assess the safety of FCM versus oral iron over an extended period. Results: The safety population included 616 patients. The incidence of one or more adverse events was 91.0, 100.0 and 105.0 per 100 patient-years in the high ferritin FCM, low ferritin FCM and oral iron groups, respectively. The incidence of adverse events with a suspected relation to study drug was 15.9, 17.8 and 36.7 per 100 patient-years in the three groups; for serious adverse events, the incidence was 28.2, 27.9 and 24.3 per 100 patient-years. The incidence of cardiac disorders and infections was similar between groups. At least one ferritin level ≄800 ”g/L occurred in 26.6% of high ferritin FCM patients, with no associated increase in adverse events. No patient with ferritin ≄800 ”g/L discontinued the study drug due to adverse events. Estimated glomerular filtration rate remained the stable in all groups. Conclusions: These results further support the conclusion that correction of iron deficiency anemia with IV FCM is safe in patients with nondialysis-dependent CKD

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    Dental students’ OMFS‐related experiences and interest in OMFS careers: An exploration

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    PurposeWhile the numbers of oral maxillofacial surgery (OMFS) residents increased over time, women and residents from underrepresented minority backgrounds are still underrepresented. The objectives were to assess dental students’ OMFS‐related personal and educational experiences and attitudes and explore which factors correlate with their interest in future OMFS careers.MethodsData were collected from 493 dental students in 1 dental school and 206 students from 15 other US and Canadian dental schools.ResultsThe students in the national sample were more likely to have experienced an OMFS procedure themselves (64.6% vs. 50.7%; P = 0.001), have shadowed an OMFS in an operating room (23.2% vs. 14.9%; P = 0.009) prior to coming to dental school and to be much/very much interested in an OMFS career (36.4% vs. 12%; P < 0.001) than the students at the home school.While the majority of both groups rated their experiences with rotations in the OMFS department in the dental school (68% vs. 62.5%) and in the hospital (80.3% vs. 85.7%) as very interesting, the students in the national sample were more likely to agree/strongly agree that they were satisfied with their OMFS experiences (68.1% vs. 36.3%; P < 0.001) and had learned a lot from the OMFS faculty (57.9% vs. 30.8%) than the students in the home school. For both groups, the degree of interest in an OMFS career correlated with having had more personal OMFS experiences (home: r = 0.28; P < 0.001/other: r = 0.39; P < 0.001), more interesting OMFS experiences in the dental school (r = 0.23; P < 0.05/r = 0.40; P < 0.001) and the hospital (0.33; P < 0.05/r = 0.50; P < 0.001) and more positive attitudes toward OMFS faculty (r = 0.26; P < 0.001/r = 0.37; P < 0.001).ConclusionsPositive personal and educational OMFS experiences and positive attitudes toward OMFS faculty were associated with an interest in OMFS careers. These findings provide a basis for developing educational interventions aimed at increasing the percentage of women and residents from URM backgrounds in OMFS programs.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/167538/1/jdd12511_am.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/167538/2/jdd12511.pd

    Volcanotectonics: the tectonics and physics of volcanoes and their eruption mechanics

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    International audienceThe physical processes that operate within, and beneath, a volcano control the frequency, duration, location and size of volcanic eruptions. Volcanotectonics focuses on such processes, combining techniques, data, and ideas from structural geology, tectonics, volcano deformation, physical volcanology, seismology, petrology, rock and fracture mechanics and classical physics. A central aim of volcanotectonics is to provide sufficient understanding of the internal processes in volcanoes so that, when combined with monitoring data, reliable forecasting of eruptions, vertical (caldera) and lateral (landslide) collapses and related events becomes possible. To gain such an understanding requires knowledge of the material properties of the magma and the crustal rocks, as well as the associated stress fields, and their evolution. The local stress field depends on the properties of the layers that constitute the volcano and, in particular, the geometric development of its shallow magma chamber. During this decade an increasing use of data from InSAR, pixel offset and structure-from-motion, as well as dense, portable seismic networks will provide further details on the mechanisms of volcanic unrest, magma-chamber rupture, the propagation of magma-filled fractures (dikes, inclined sheets and sills) and lateral and vertical collapse. Additionally, more use will be made of accurate quantitative data from fossil and active volcanoes, combined with realistic numerical, analytical and machine-learning studies, so as to provide reliable models on volcano behaviour and eruption forecasting

    Evaluation of a quality improvement intervention to reduce anastomotic leak following right colectomy (EAGLE): pragmatic, batched stepped-wedge, cluster-randomized trial in 64 countries

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    Background Anastomotic leak affects 8 per cent of patients after right colectomy with a 10-fold increased risk of postoperative death. The EAGLE study aimed to develop and test whether an international, standardized quality improvement intervention could reduce anastomotic leaks. Methods The internationally intended protocol, iteratively co-developed by a multistage Delphi process, comprised an online educational module introducing risk stratification, an intraoperative checklist, and harmonized surgical techniques. Clusters (hospital teams) were randomized to one of three arms with varied sequences of intervention/data collection by a derived stepped-wedge batch design (at least 18 hospital teams per batch). Patients were blinded to the study allocation. Low- and middle-income country enrolment was encouraged. The primary outcome (assessed by intention to treat) was anastomotic leak rate, and subgroup analyses by module completion (at least 80 per cent of surgeons, high engagement; less than 50 per cent, low engagement) were preplanned. Results A total 355 hospital teams registered, with 332 from 64 countries (39.2 per cent low and middle income) included in the final analysis. The online modules were completed by half of the surgeons (2143 of 4411). The primary analysis included 3039 of the 3268 patients recruited (206 patients had no anastomosis and 23 were lost to follow-up), with anastomotic leaks arising before and after the intervention in 10.1 and 9.6 per cent respectively (adjusted OR 0.87, 95 per cent c.i. 0.59 to 1.30; P = 0.498). The proportion of surgeons completing the educational modules was an influence: the leak rate decreased from 12.2 per cent (61 of 500) before intervention to 5.1 per cent (24 of 473) after intervention in high-engagement centres (adjusted OR 0.36, 0.20 to 0.64; P &lt; 0.001), but this was not observed in low-engagement hospitals (8.3 per cent (59 of 714) and 13.8 per cent (61 of 443) respectively; adjusted OR 2.09, 1.31 to 3.31). Conclusion Completion of globally available digital training by engaged teams can alter anastomotic leak rates. Registration number: NCT04270721 (http://www.clinicaltrials.gov)
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