8,552 research outputs found
Development and operation of a pixel segmented liquid-filled linear array for radiotherapy quality assurance
A liquid isooctane (CH) filled ionization linear array for
radiotherapy quality assurance has been designed, built and tested. The
detector consists of 128 pixels, each of them with an area of 1.7 mm
1.7 mm and a gap of 0.5 mm. The small pixel size makes the detector ideal for
high gradient beam profiles like those present in Intensity Modulated Radiation
Therapy (IMRT) and radiosurgery. As read-out electronics we use the X-Ray Data
Acquisition System (XDAS) with the Xchip developed by the CCLRC.
Studies concerning the collection efficiency dependence on the polarization
voltage and on the dose rate have been made in order to optimize the device
operation.
In the first tests we have studied dose rate and energy dependences, and
signal reproducibility. Dose rate dependence was found lower than 2.5 % up to 5
Gy min, and energy dependence lower than 2.1 % up to 20 cm depth in
solid water. Output factors and penumbras for several rectangular fields have
been measured with the linear array and were compared with the results obtained
with a 0.125 cm air ionization chamber and radiographic film,
respectively. Finally, we have acquired profiles for an IMRT field and for a
virtual wedge. These profiles have also been compared with radiographic film
measurements. All the comparisons show a good correspondence. Signal
reproducibility was within a 2% during the test period (around three months).
The device has proved its capability to verify on-line therapy beams with
good spatial resolution and signal to noise ratio.Comment: 16 pages, 12 figures Submitted to Phys. Med. Bio
From Heisenberg matrix mechanics to EBK quantization: theory and first applications
Despite the seminal connection between classical multiply-periodic motion and
Heisenberg matrix mechanics and the massive amount of work done on the
associated problem of semiclassical (EBK) quantization of bound states, we show
that there are, nevertheless, a number of previously unexploited aspects of
this relationship that bear on the quantum-classical correspondence. In
particular, we emphasize a quantum variational principle that implies the
classical variational principle for invariant tori. We also expose the more
indirect connection between commutation relations and quantization of action
variables. With the help of several standard models with one or two degrees of
freedom, we then illustrate how the methods of Heisenberg matrix mechanics
described in this paper may be used to obtain quantum solutions with a modest
increase in effort compared to semiclassical calculations. We also describe and
apply a method for obtaining leading quantum corrections to EBK results.
Finally, we suggest several new or modified applications of EBK quantization.Comment: 37 pages including 3 poscript figures, submitted to Phys. Rev.
Solar Coronal Structures and Stray Light in TRACE
Using the 2004 Venus transit of the Sun to constrain a semi-empirical
point-spread function for the TRACE EUV solar telescope, we have measured the
effect of stray light in that telescope. We find that 43% of 171A EUV light
that enters TRACE is scattered, either through diffraction off the entrance
filter grid or through other nonspecular effects. We carry this result forward,
via known-PSF deconvolution of TRACE images, to identify its effect on analysis
of TRACE data. Known-PSF deconvolution by this derived PSF greatly reduces the
effect of visible haze in the TRACE 171A images, enhances bright features, and
reveals that the smooth background component of the corona is considerably less
bright (and hence much more rarefied) than commonly supposed. Deconvolution
reveals that some prior conlclusions about the Sun appear to have been based on
stray light in the images. In particular, the diffuse background "quiet corona"
becomes consistent with hydrostatic support of the coronal plasma; feature
contrast is greatly increased, possibly affecting derived parameters such as
the form of the coronal heating function; and essentially all existing
differential emission measure studies of small features appear to be affected
by contamination from nearby features. We speculate on further implications of
stray light for interpretation of EUV images from TRACE and similar
instruments, and advocate deconvolution as a standard tool for image analysis
with future instruments such as SDO/AIA.Comment: Accepted by APJ; v2 reformatted to single-column format for online
readabilit
No elliptic islands for the universal area-preserving map
A renormalization approach has been used in \cite{EKW1} and \cite{EKW2} to
prove the existence of a \textit{universal area-preserving map}, a map with
hyperbolic orbits of all binary periods. The existence of a horseshoe, with
positive Hausdorff dimension, in its domain was demonstrated in \cite{GJ1}. In
this paper the coexistence problem is studied, and a computer-aided proof is
given that no elliptic islands with period less than 20 exist in the domain. It
is also shown that less than 1.5% of the measure of the domain consists of
elliptic islands. This is proven by showing that the measure of initial
conditions that escape to infinity is at least 98.5% of the measure of the
domain, and we conjecture that the escaping set has full measure. This is
highly unexpected, since generically it is believed that for conservative
systems hyperbolicity and ellipticity coexist
Search for antiproton decay at the Fermilab Antiproton Accumulator
A search for antiproton decay has been made at the Fermilab Antiproton
Accumulator. Limits are placed on thirteen antiproton decay modes. The results
include the first explicit experimental limits on the muonic decay modes of the
antiproton, and the first limits on the decay modes e- gamma gamma, and e-
omega. The most stringent limit is for the decay mode pbar-> e- gamma. At 90%
C.L. we find that tau/B(pbar-> e- gamma) > 7 x 10^5 yr. The most stringent
limit for decay modes with a muon in the final state is for the decay pbar->
mu- gamma. At 90% C.L. we find that tau/B(pbar-> mu- gamma) > 5 x 10^4 yr.Comment: 20 pages, 8 figures. Submitted to Phys. Rev. D. Final results on 13
channels (was 15) are presente
Voluntary Wheel Running Augments Vascular Function in Rats with Chronic Kidney Disease
Please view abstract in the attached PDF file
Can Streamer Blobs prevent the Buildup of the Interplanetetary Magnetic Field?
Coronal Mass Ejections continuously drag closed magnetic field lines away
from the Sun, adding new flux to the interplanetary magnetic field (IMF). We
propose that the outward-moving blobs that have been observed in helmet
streamers are evidence of ongoing, small-scale reconnection in streamer current
sheets, which may play an important role in the prevention of an indefinite
buildup of the IMF. Reconnection between two open field lines from both sides
of a streamer current sheet creates a new closed field line, which becomes part
of the helmet, and a disconnected field line, which moves outward. The blobs
are formed by plasma from the streamer that is swept up in the trough of the
outward moving field line. We show that this mechanism is supported by
observations from SOHO/LASCO. Additionally, we propose a thorough statistical
study to quantify the contribution of blob formation to the reduction of the
IMF, and indicate how this mechanism may be verified by observations with
SOHO/UVCS and the proposed NASA STEREO and ESA Polar Orbiter missions.Comment: 7 pages, 2 figures; accepted by The Astrophysical Journal Letters;
uses AASTe
Protein processing characterized by a gel-free proteomics approach
We describe a method for the specific isolation of representative N-terminal peptides of proteins and their proteolytic fragments. Their isolation is based on a gel-free, peptidecentric proteomics approach using the principle of diagonal chromatography. We will indicate that the introduction of an altered chemical property to internal peptides holding a free α-N-terminus results in altered column retention of these peptides, thereby enabling the isolation and further characterization by mass spectrometry of N-terminal peptides. Besides pointing to changes in protein expression levels when performing such proteome surveys in a differential modus, protease specificity and substrate repertoires can be allocated since both are specified by neo-N-termini generated after a protease cleavage event. As such, our gel-free proteomics technology is widely applicable and amenable for a variety of proteome-driven protease degradomics research
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