Estudio científico del Mihrab de la antigua mezquita de Almería

En este trabajo se realiza un estudio de los distintos materiales empleados en la construcción, tanto originales como añadidos, las distintas intervenciones rea lizadas en el Mihrab de la antigua Mezquita de Almería. El estudio de las mues tras ha permitido determinar la naturaleza de cada una de ellas, así como la exis tencia de gran cantidad de sales (clomros y sulfatos en su mayoría). Asimismo, se ha obtenido información sobre su micromorfología. porosidad, mayor o me nor grado de cristalinidad y estado de alteración. Finalmente se ha comprobado la aplicación, en época reciente, de consolidantes que han sido responsables del desprendimiento superficial

Quinolone Resistance Reversion by Targeting the SOS Response

Suppression of the SOS response has been postulated as a therapeutic strategy for potentiating antimicrobial agents. We aimed to evaluate the impact of its suppression on reversing resistance using a model of isogenic strains of Escherichia coli representing multiple levels of quinolone resistance. E. coli mutants exhibiting a spectrum of SOS activity were constructed from isogenic strains carrying quinolone resistance mechanisms with susceptible and resistant phenotypes. Changes in susceptibility were evaluated by static (MICs) and dynamic (killing curves or flow cytometry) methodologies. A peritoneal sepsis murine model was used to evaluate in vivo impact. Suppression of the SOS response was capable of resensitizing mutant strains with genes encoding three or four different resistance mechanisms (up to 15-fold reductions in MICs). Killing curve assays showed a clear disadvantage for survival (Δlog10 CFU per milliliter [CFU/ml] of 8 log units after 24 h), and the in vivo efficacy of ciprofloxacin was significantly enhanced (Δlog10 CFU/g of 1.76 log units) in resistant strains with a suppressed SOS response. This effect was evident even after short periods (60 min) of exposure. Suppression of the SOS response reverses antimicrobial resistance across a range of E. coli phenotypes from reduced susceptibility to highly resistant, playing a significant role in increasing the in vivo efficacy

Regulon-Specific Control of Transcription Elongation across the Yeast Genome

Transcription elongation by RNA polymerase II was often considered an invariant non-regulated process. However, genome-wide studies have shown that transcriptional pausing during elongation is a frequent phenomenon in tightly-regulated metazoan genes. Using a combination of ChIP-on-chip and genomic run-on approaches, we found that the proportion of transcriptionally active RNA polymerase II (active versus total) present throughout the yeast genome is characteristic of some functional gene classes, like those related to ribosomes and mitochondria. This proportion also responds to regulatory stimuli mediated by protein kinase A and, in relation to cytosolic ribosomal-protein genes, it is mediated by the silencing domain of Rap1. We found that this inactive form of RNA polymerase II, which accumulates along the full length of ribosomal protein genes, is phosphorylated in the Ser5 residue of the CTD, but is hypophosphorylated in Ser2. Using the same experimental approach, we show that the in vivo–depletion of FACT, a chromatin-related elongation factor, also produces a regulon-specific effect on the expression of the yeast genome. This work demonstrates that the regulation of transcription elongation is a widespread, gene class–dependent phenomenon that also affects housekeeping genes

Analysis Gender Stereotypes in perception profile of conduct in track and field

In our current world, the existance of obstacles to acknowledge women’s equal abiliAes is real. Legally there are no barriers. The Sports Act of the government of Andalusia (Law 5/2016, July 19) determines the right to equality between genders. This is what has been called the glass ceiling. Gender stereotypes about behavior profile recreate constraints that occur in everyday pracAces, power relaAons and insAtuAonal arrangements of the general social order. Thee stereotypes are rooted in sports. In this sense. The objecAve of this study was to "interprete different gender stereotypes that exist regarding men’s and women’s profile of conduct in athleAcs.

Bibliografía [Cuadernos del Instituto Antonio de Nebrija de estudios sobre la Universidad. 2006, nº 9]

Publicad

On the use of many-core machines for the acceleration of a mesh truncation technique for FEM

Finite element method (FEM) has been used for years for radiation problems in the field of electromagnetism. To tackle problems of this kind, mesh truncation techniques are required, which may lead to the use of high computational resources. In fact, electrically large radiation problems can only be tackled using massively parallel computational resources. Different types of multi-core machines are commonly employed in diverse fields of science for accelerating a number of applications. However, properly managing their computational resources becomes a very challenging task. On the one hand, we present a hybrid message passing interface + OpenMP-based acceleration of a mesh truncation technique included in a FEM code for electromagnetism in a high-performance computing cluster equipped with 140 compute nodes. Results show that we obtain about 85% of the theoretical maximum speedup of the machine. On the other hand, a graphics processing unit has been used to accelerate one of the parts that presents high fine-grain parallelism.This work has been fnancially supported by TEC2016-80386-P, TIN2017-82972-R, CAM S2013/ICE-3004 projects and “Ayudas para contratos predoctorales de Formación del Profesorado Universitario FPU”

Fuzzy PD+I Embedded Control System for a Multi-Phase DC-DC Bidirectional Converter

[EN] In this work is presented the design of a Fuzzy PD+I control system applied to the voltage control of a multi-phase DC-DC power electronic converter. The fuzzy controller has two inputs. The first input, named Error, is the difference between the desired voltage value in the output of the converter and the measured voltage at this particular point; the second input is defined by the changes in the measured voltage of the converter. The control system is embedded in the NI myRIO-1900 development kit, using LabVIEW as programming software employing the embedded system for experimental tests with a prototype of the converter. This control system allows the stabilization of the converter in the buck and boost operation modes, showing an appropriate behavior at the startup and under resistive load changes, presenting acceptable times for DC microgrids future applications while connecting the DC bus with supercapacitors or a battery bank.[ES] En este trabajo se presenta el diseño de un sistema de control difuso PD+I embebido aplicado en el control de voltaje de un convertidor electrónico de potencia bidireccional multi-fase CD-CD. El controlador difuso cuenta con dos entradas, la primera se le denomina Error y es la diferencia entre el valor de voltaje deseado en la salida del convertidor y el voltaje medido en la salida del mismo; la segunda entrada es definida por las variaciones en el voltaje medido. La salida del controlador difuso define las variaciones en el ciclo de trabajo de los interruptores de potencia que controlan el convertidor. El sistema de control difuso se embebió en la tarjeta de desarrollo NI myRIO-1900 utilizando como software de programación LabVIEW, empleando el sistema embebido para realizar pruebas experimentales con el prototipo del convertidor. Con este sistema de control de voltaje se logra estabilizar el convertidor en los modos de operación reductor y elevador, demostrando un adecuado comportamiento del convertidor en el arranque y ante cambios de carga resistiva, manteniendo tiempos aceptables para aplicaciones futuras en micro-redes de CD conectando el bus de CD con un banco de super-capacitores o un banco de baterías.Martínez Nolasco, JJ.; Rodríguez, E.; Rodríguez, H.; Morfin, J.; Padilla, A. (2018). Fuzzy PD+I Embedded Control System for a Multi-Phase DC-DC Bidirectional Converter. Revista Iberoamericana de Automática e Informática industrial. 15(4):457-466. https://doi.org/10.4995/riai.2018.8721OJS457466154Baek J. B., Choi, W. I., Cho, B. H., 2013. Digital adaptive frequency modulation for bidirectional DC-DC converter. IEEE Transactions on Industrial Electronics, 60(11), 5167-5176. DOI: 10.1109/TIE.2012.2224075Bolognani S., Morandin M., Calligaro S., Petrella R., Pevere A., 2014. Bidirectional PMSM drive employing a three level ANPC inverter and a multi-phase interleaved DC/DC converter for hybrid electric vehicles. Twenty-Ninth Annual IEEE in Applied Power Electronics Conference and Exposition (APEC), IEEE, 818-825. DOI: 10.1109/APEC.2014.6803402Brox M., Sánchez S., del Toro E., Brox P., Moreno F. J., 2013. CAD tools for hardware implementation of embedded fuzzy systems on FPGAs. IEEE Transactions on Industrial Informatics, 9(3), 1635-1644. DOI: 10.1109/TII.2012.2228871Burrett R., Clini C., Dixon R., Eckhart M., El-Ashry M., Gupta D., Houssin D., 2009. Renewable Energy Policy Network for the 21st Century.Dusmez S., Hasanzadeh A., Khaligh A., 2015. Comparative analysis of bidirectional three-level DC-DC converter for automotive applications. IEEE Transactions on Industrial Electronics, 62(5), 3305-3315. DOI: 10.1109/TIE.2014.2336605Hart D., 2011. Power Electronics, 1ra ed., McGraw-Hill, New York. 198-220.Hegazy O., Van Mierlo J., Lataire P., 2011. Design and control of bidirectional DC/AC and DC/DC converters for plug-in hybrid electric vehicles. International Conference in Power Engineering, Energy and Electrical Drives (POWERENG), IEEE, 1-7. DOI: 10.1109/PowerEng.2011.6036530Hossain M. I., Khan S. A., Shafiullah M., Hossain M. J. 2011. Design and implementation of MPPT controlled grid connected photovoltaic system. Symposium in Computers & Informatics (ISCI), IEEE, 284-289. DOI: 10.1109/ISCI.2011.5958928Khan S. A., Hossain M. I., 2010. Design and implementation of microcontroller based fuzzy logic control for maximum power point tracking of a photovoltaic system. International Conference in Electrical and Computer Engineering (ICECE), IEEE, 322-325. DOI: 10.1109/ICELCE.2010.5700693Kumar A., Gaur P., 2014. Bidirectional DC/DC converter for hybrid electric vehicle. International Conference in Advances in Computing, Communications and Informatics (ICACCI), IEEE, 839-843. DOI: 10.1109/ICACCI.2014.6968295Lee S. Y., Pfaelzer A. G., van Wyk, J. D., 2004. Thermal analysis for improved packaging of 4-channel 42 V/14 V DC/DC converter. 39th IAS Annual Meeting in Industry Applications Conference Vol. 4, IEEE, 2330-2336. DOI: 10.1109/IAS.2004.1348800Lee S. Y., Pfaelzer A. G., van Wyk J. D., 2007. Comparison of different designs of a 42-V/14-V dc/dc converter regarding losses and thermal aspects. IEEE Transactions on Industry Applications, 43(2), 520-530. DOI: 10.1109/TIA.2006.889808Liu D., Hu A., Wang G., Hu W., 2010. Current sharing schemes for multiphase interleaved DC/DC converter with FPGA implementation. International Conference in Electrical and Control Engineering (ICECE), IEEE, 3512-3515. DOI: 10.1109/iCECE.2010.854Markvart T., 2006. Microgrids: Power systems for the 21st century. Refocus, 7(4), 44-48.Martínez, J. J., Padilla-Medina, J. A., Cano-Andrade, S., Sancen, A., Prado, J., & Barranco, A. I. (2018). Development and Application of a Fuzzy Control System for a Lead-Acid Battery Bank Connected to a DC Microgrid. International Journal of Photoenergy, 2018.Omara A. M., Sleptsov M. A., 2016. Comparative study of different electric propulsion system configurations based on IPMSM drive for battery electric vehicles. International Conference in Electrical Machines and Systems (ICEMS), IEEE, 1-6.Sánchez S., Cabrera A., Baturone M. I., Moreno F. J., Brox M., 2007. FPGA implementation of embedded fuzzy controllers for robotic applications. IEEE Transactions on Industrial Electronics, 54(4), 1937-1945. DOI: http://dx.doi.org/10.1109/TIE.2007.898292Santos M., 2011. Un enfoque aplicado del control inteligente. Revista Iberoamericana de Automática e Informática Industrial RIAI, 8(4), 283-296. DOI: 10.1016/j.riai.2011.09.016Sikkabut S., Mungporn P., Ekkaravarodome C., Bizon N., Tricoli P., Nahid-Mobarakeh B., Thounthong P., 2016. Control of High-Energy High-Power Densities Storage Devices by Li-ion Battery and Supercapacitor for Fuel Cell/Photovoltaic Hybrid Power Plant for Autonomous System Applications. IEEE Transactions on Industry Applications, 52(5), 4395-4407. DOI: 10.1109/TIA.2016.2581138Thao N. G. M., Dat M. T., Binh T. C., Phuc N. H., 2010. PID-fuzzy logic hybrid controller for grid-connected photovoltaic inverters. International Forum in Strategic Technology (IFOST), IEEE, 140-144. DOI: 10.1109/IFOST.2010.5668024Vanti V. M., Leite L. C., Batista E. A., 2015. Monitoring and control of the processes involved in the capture and filtering of biogas using FPGA embedded fuzzy logic. IEEE Latin America Transactions, 13(7), 2232-2238. DOI: 10.1109/TLA.2015.7273782Yang Y., Li T., Liu J., Li H., 2012. A comprehensive analysis of coupled inductors in 4 phases interleaving bidirectional DC/DC converter. International Symposium in Power Electronics for Distributed Generation Systems (PEDG), IEEE, 603-607. DOI: 10.1109/PEDG.2012.6254064Yang Y., Ma J., Ma Y., Zou Y., 2014. The universal design criterion of coupled inductor in multiphase interleaving and magnetically integrated bidirectional DC/DC converter. Conference and Exposition International in Power Electronics and Application, IEEE, 1008-1013. DOI: 10.1109/PEAC.2014.7037998Yang Y., Dai S., 2015. Design criterion for asymmetric coupled inductors in interleaving & magnetically integrated bidirectional DC/DC converter. 2nd Conference International in Future Energy Electronics, IEEE, 1-11. DOI: 10.1109/IFEEC.2015.7361443Yu, B. (2016). Design and experimental results of battery charging system for microgrid system. International Journal of Photoenergy, 2016

Optimal location of exit doors for efficient evacuation of crowds at gathering places

This work deals with the optimal design for the location of the exit doors at meeting places (such as sports centers, public squares, street markets, transport stations, etc.) to guarantee a safer emergency evacuation in events of a sporting, social, entertainment or religious type. This problem is stated as an optimal control problem of nonlinear partial differential equations, where the state system is a reformulation of the Hughes model (coupling the eikonal equation for a density-weighted walking velocity of pedestrians and the continuity equation for conservation of the pedestrian density), the control is the location of the exit doors at the domain boundary (subject to several geometric constraints), and the cost function is related to the evacuation rate. We provide a full numerical algorithm for solving the problem (a finite element technique for the discretization and a gradient-free procedure for the optimization), and show several numerical results for a realistic case.Ministerio de Ciencia e Innovación | Ref. TED2021-129324B-I00Sistema Nacional de Investigadores, México | Ref. SNI-52768Programa para el Desarrollo Profesional Docente (México) | Ref. PRODEP/103.5/16/8066CONACyT | Ref. 21755

Towards a more efficient evacuation of crowds by means of an optimal location of exit doors

In this work we present a new strategy, employing optimal control techniques of partial differential equations, to automate the optimization of locations for a given number of exit doors at gathering places, so that the evacuation of crowds takes place in a safer and faster way. Once given a detailed mathematical formulation of the problem, in order to solve the constrained optimal control problem numerically, we propose its full discretization, with a space semi-discretization via the finite element method over a family of triangular meshes of the domain under study, and a time semi-discretization via the Euler algorithm. Finally, for the resulting discretized minimization problem, we try its optimization by means of a derivative-free algorithm. Numerical examples, corresponding to different scenarios for a real-world study case posed on “Plaza de la Liberacion” (Guadalajara, Mexico), are presented and discussed to assess the effectiveness of our approach

Mastitis bovina de orígen micótico: descripción de un caso.

El estudio se realizó en una hacienda ubicada en un municipio de Cundinamarca a una altitud de 340 metros y una temperatura promedio de 26 grados centígrados, con 185 animales de la raza Pardo Suizo y mestizo (Pardo Suizo x Cebú) de los cuales 105 estaban en producción de leche y los demás estaban en el horro o en proceso de cría y levante. Se practicó una visita a la finca para evaluar y diagnosticar un brote de mastitis que afectaba a 63 animales del hato en forma clínica aguda. Se realizó un chequeo general con la prueba de mastitis california (MC) en todos los animales del hato dando un resultado positivo en 148 cuartos de 68 vacas. Se procedió a tratar a los animales afectados con productos antibacterianos pero con resultados negativos. Posteriormente se tomaron muestras de secreciones de los cuartos afectados que se cultivaron en agar sangre al 5 por ciento con incubación a 37 grados centígrados por 72 horas, agar sabouraud incubado a 28 grados centígrados por 4 días y agar MacConkey a 37 grados centígrados por 72 horas. Los resultados microbiológicos e histopatológicos definen el diagnóstico de mastitis micótica. Establecido el carácter micótico de la enfermedad, se suspendió todo producto antibacteriano y se inició una terapia para atacar al hongo. Una vez terminado el tratamiento se hizo notoria la recuperación clínica y productiva en 50 animales. Los 13 restantes desarrollaron un estado de fibrosis de la glándula mamaria que obligó a su eliminación Para buscar el origen de la infección se examinó el antibiótico y las sondas plásticas empleadas en el tratamiento. Descartada la fuente de contaminación en el antibiótico y en las sondas la misma se puede atribuír al agua utilizada durante los tratamientos como diluyenteGanado de leche-Ganadería lech