220 research outputs found
Assessing the impact on clinical internship of problem-based learning applied to nursing studies
Resultados parciales de esta
investigación fueron presentados
en el XVIII Congreso de la Sociedad
Española de Educación Médica y
publicados como comunicación
en Educ Med 2007; 10: 167Objetivo. Evaluar el impacto en la práctica clínica de la implantación de la metodología del aprendizaje basado en problemas
(ABP) aplicada a los estudios de enfermería.
Sujetos y métodos. Estudio longitudinal prospectivo en dos cohortes de estudiantes de enfermería: el grupo intervención
fue la promoción 2005-2006 de la escuela de enfermería, que recibió su educación con la metodología del ABP, y el
grupo control fue la promoción de 2004-2005, que recibió su formación a través de otras metodologías docentes, fundamentalmente
clases magistrales y seminarios. Se analizó la posible asociación, en cada uno de los elementos del formulario
de evaluación del tutor, entre la calificación obtenida por los estudiantes y la metodología de aprendizaje empleada
durante su educación (ABP o no ABP). Los criterios de evaluación fueron: responsabilidad, iniciativa, habilidad y destreza
en técnicas y procedimientos manuales, organización y metodología en las actividades, comunicación/relación con usuarios
y familiares y comunicación/relación con el equipo de trabajo, y grado de consecución de los objetivos docentes.
Resultados. Se obtuvieron 651 formularios de evaluación válidos, 383 para el grupo control y 268 para el grupo intervención.
Se encontraron diferencias estadísticamente significativas sólo en el tercer año, en la categoría ‘habilidad y destreza
en las técnicas relacionadas con los procedimientos manuales’ (p = 0,007). El grupo control obtuvo una mejor puntuación.
Conclusiones. Los resultados sugieren que el uso de ABP en la formación académica de los estudiantes de enfermería no
modifica la puntuación obtenida en su práctica clínica en las categorías recogidas en nuestra herramienta de evaluaciónAim. To assess the impact on clinical internship of problem-based learning (PBL) methodology applied to nursing studies.
Subjects and methods. Longitudinal and prospective study of two cohorts of nursing students: the intervention group
was the promotion 2005-2006 of the nursing school, that received their education with PBL, and the control group was the
promotion 2004-2005 of the nursing school, that received their education with other pedagogic methods, mainly lectures
and seminars. We analysed the possible correlation in each of the items on the mentor’s assessment form between the grade
obtained by students and the learning methodology employed during their education (PBL or non-PBL). The assessment
criteria were: responsibility; initiative; skill and proficiency in techniques related to manual procedures; organization
and methodology in activities carried out; communication/relationship with patients and families; communication/
relationship with the work team; and degree to which training objectives were reached.
Results. We had 651 valid assessment forms, 383 for the control group and 268 for the intervention group. Clear significant
differences were found only in the third year, in the ‘skill and proficiency in techniques related to manual process’ category
(p = 0.007). The control group had higher scores.
Conclusions. The results suggest that the use of PBL in students’ academic coursework does not modify the score obtained
in their clinical internship on the items specified in our assessment toolFondo de Investigaciones Sanitarias
del Ministerio de Sanidad y
Consumo (proyecto PI052806
Community nutrition in Spain: advances and drawbacks
Scientific evidence has placed community nutrition among the front-line strategies
in health promotion. Community nutrition in different regions of Spain has
developed at an unequal pace. Early initiatives in the mid 1980s provided
good-quality population data and established a basis for nutrition surveillance
including individual body measurements, dietary intake data, information on
physical activity, and biomarkers. The Nutrition and Physical Activity for Obesity
Prevention Strategy (NAOS) reinforces community nutrition action in Spain.
Presented here is an overview of developments in community nutrition in Spain in
recent years as well as potential trends under the scope of the NAOS.Publicad
Cataract Surgery in Elderly Subjects with Heterozygous Familial Hypercholesterolemia in Prolonged Treatment with Statins
Background: Cataracts are the main cause of blindness and represent one fifth of visual problems worldwide. It is still unknown whether prolonged statin treatment favors the development of cataracts. We aimed to ascertain the prevalence of cataract surgery in elderly subjects with genetically diagnosed heterozygous familial hypercholesterolemia (HeFH) receiving statin treatment for ≥5 years, and compare this with controls. Methods: This is an observational, multicenter, case–control study from five lipid clinics in Spain. We collected data with the following inclusion criteria: age ≥65 years, LDL cholesterol levels ≥220 mg/dL without lipid-lowering drugs, a pathogenic mutation in a candidate gene for HeFH (LDLR, APOB, or PCSK9) and statin treatment for ≥5 years. Controls were selected from relatives of HeFH patients without hypercholesterolemia. Linear and logistic regressions based on generalized linear models and generalized estimating equations (GEE) were used. Cataract surgery was used as a proxy for cataract development. Results: We analyzed 205 subjects, 112 HeFH, and 93 controls, with a mean age of 71.8 (6.5) and 70.0 (7.3) years, respectively. HeFH subjects presented no difference in clinical characteristics, including smoking, hypertension, and type 2 diabetes mellitus, compared with controls. The mean duration of lipid-lowering treatment in HeFH was 22.5 (8.7) years. Cataract surgery prevalence was not significantly different between cases and controls. The presence of cataracts was associated neither with LDLc nor with the length of the statin therapy. Conclusion: In the present study, HeFH was not a risk factor for cataract surgery and prolonged statin treatment did not favor it either. These findings suggest that statin treatment is not related with cataracts
Prospective multicenter study of carbapenemase-producing Enterobacteriaceae from 83 hospitals in Spain reveals high in vitro susceptibility to colistin and meropenem
The aim of this study was to determine the impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2013 by describing the prevalence, dissemination, and geographic distribution of CPE clones, and their population structure and antibiotic susceptibility. From February 2013 to May 2013, 83 hospitals (about 40,000 hospital beds) prospectively collected nonduplicate Enterobacteriaceae using the screening cutoff recommended by EUCAST. Carbapenemase characterization was performed by phenotypic methods and confirmed by PCR and sequencing. Multilocus sequencing types (MLST) were determined for Klebsiella pneumoniae and Escherichia coli. A total of 702 Enterobacteriaceae isolates met the inclusion criteria; 379 (54%) were CPE. OXA-48 (71.5%) and VIM-1 (25.3%) were the most frequent carbapenemases, and K. pneumoniae (74.4%), Enterobacter cloacae (10.3%), and E. coli (8.4%) were the species most affected. Susceptibility to colistin, amikacin, and meropenem was 95.5%, 81.3%, and 74.7%, respectively. The most prevalent sequence types (STs) were ST11 and ST405 for K. pneumoniae and ST131 for E. coli. Forty-five (54.1%) of the hospitals had at least one CPE case. For K. pneumoniae, ST11/OXA-48, ST15/OXA-48, ST405/OXA-48, and ST11/VIM-1 were detected in two or more Spanish provinces. ST11 isolates carried four carbapenemases (VIM-1, OXA-48, KPC-2, and OXA-245), but ST405 isolates carried OXA-48 only. A wide interregional spread of CPE in Spain was observed, mainly due to a few successful clones of OXA-48-producing K. pneumoniae (e.g., ST11 and ST405). The dissemination of OXA-48-producing E. coli is a new finding of public health concern. According to the susceptibilities determined in vitro, most of the CPE (94.5%) had three or more options for antibiotic treatmentFondo de Investigación Sanitaria PI12/01242General de Redes y Centros de Investigación Cooperativa y Ministerio de Economía y Competitividad y Spanish Network for Research in Infectious Diseases REIPI RD12/001
Inhibitor-resistant TEM- and OXA-1-producing Escherichia coli isolates resistant to amoxicillin-clavulanate are more clonal and possess lower virulence gene content than susceptible clinical isolates
In a previous prospective multicenter study in Spain, we found that OXA-1 and inhibitor-resistant TEM (IRT) β-lactamases constitute the most common plasmid-borne mechanisms of genuine amoxicillin-clavulanate (AMC) resistance in Escherichia coli. In the present study, we investigated the population structure and virulence traits of clinical AMC-resistant E. coli strains expressing OXA-1 or IRT and compared these traits to those in a control group of clinical AMC-susceptible E. coli isolates. All OXA-1-producing (n = 67) and IRT-producing (n = 45) isolates were matched by geographical and temporal origin to the AMC-susceptible control set (n = 56). We performed multilocus sequence typing and phylogenetic group characterization for each isolate and then studied the isolates for the presence of 49 virulence factors (VFs) by PCR and sequencing. The most prevalent clone detected was distinct for each group: group C isolates of sequence type (ST) 88 (C/ST88) were the most common in OXA-1 producers, B2/ST131 isolates were the most common in IRT producers, and B2/ST73 isolates were the most common in AMC-susceptible isolates. The median numbers of isolates per ST were 3.72 in OXA-1 producers, 2.04 in IRT producers, and 1.69 in AMC-susceptible isolates; the proportions of STs represented by one unique isolate in each group were 19.4%, 31.1%, and 48.2%, respectively. The sum of all VFs detected, calculated as a virulence score, was significantly higher in AMC-susceptible isolates than OXA-1 and IRT producers (means, 12.5 versus 8.3 and 8.2, respectively). Our findings suggest that IRT- and OXA-1-producing E. coli isolates resistant to AMC have a different and less diverse population structure than AMC-susceptible clinical E. coli isolates. The AMC-susceptible population also contains more VFs than AMC-resistant isolates.This study was supported by the Plan Nacional de I+D+i 2008-2011 and the Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Economía y Competitividad, Spanish Network for Research in Infectious Diseases (REIPI RD12/0015). The study was cofinanced by the European Development Regional Fund (ERDF; A way to achieve Europe) and the Fondo de Investigación Sanitaria (grant PI09/0917).S
Usual Dietary Intake, Nutritional Adequacy and Food Sources of Calcium, Phosphorus, Magnesium and Vitamin D of Spanish Children Aged One to <10 Years. Findings from the EsNuPI Study
Bone problems in the population begin to be establish in childhood. The present study aims to assess the usual calcium, phosphorus, magnesium, and vitamin D intakes, along with the food sources of these nutrients, in Spanish children participating in the EsNuPI (Estudio Nutricional en Población Infantil Española) study. Two 24 h dietary recalls were applied to 1448 children (1 to <10 years) divided into two sub-samples: one reference sample (RS) of the general population [n = 707] and another sample which exclusively included children consuming enriched or fortified milks, here called “adapted milks” (AMS) [n = 741]. Estimation of the usual intake shows that nutrient intake increased with age for all nutrients except vitamin D. Using as reference the Dietary Reference Values from the European Food Safety Authority (EFSA), calcium and magnesium intakes were found to be below the average requirement (AR) and adequate intake (AI), respectively, in a considerable percentage of children. Furthermore, phosphorus exceeded the AI in 100% of individuals and vitamin D was lower than the AI in almost all children studied. The results were very similar when considering only plausible reporters. When analyzing the food sources of the nutrients studied, milk and dairy products contributed the most to calcium, phosphorus, magnesium, and vitamin D. Other sources of calcium were cereals and vegetables; for phosphorus: meat, meat products, and cereals; for magnesium: cereals and fruits; and, for vitamin D: fish and eggs. These results highlight the desirability of improving the intake concerning these nutrients, which are involved in bone and metabolic health in children. The AMS group appeared to contribute better to the adequacy of those nutrients than the RS group, but both still need further improvement. Of special interest are the results of vitamin D intakes, which were significantly higher in the AMS group (although still below the AI), independent of ageThis research was funded by Instituto Puleva de Nutrición (IPN)S
Dietary and Lifestyle Patterns in the Spanish Pediatric Population (One to <10 Years Old): Design, Protocol, and Methodology of the EsNuPI Study
The interest in a healthy diet and lifestyle during the early stages of life increased, pointing
out its role in the development of noncommunicable chronic diseases throughout adult life. Dietary
habits and dietary patterns begin to be established in early childhood and persist during adulthood.
Therefore, the EsNuPI (“Nutritional Study in Spanish Pediatric Population”) study aims to depict the
dietary patterns, physical activity, and sedentary behaviors in Spanish children aged from one to
<10 years old. This prospective, cross-sectional, observational study recruited a total of 1514 children
from Spanish cities with >50,000 inhabitants, stratified by Nielsen areas. Participants were involved
in one face-to-face survey, followed by a telephone survey after at least one week. Information
about dietary intake and habits was obtained using a quantitative food frequency questionnaire
and two 24-h dietary recalls. Physical activity and sedentary behaviors were registered using a
specific questionnaire based on a seven-day record. Data were processed and stratified by categorical
variables to be statistically analyzed in order to meet the study objectives. This study is the first of its kind in a Spanish reference population of this age range and the first to evaluate whether
the consumption of adapted milk formulas and dairy products is associated with healthier dietary
patterns and better diet quality and lifestyles in this group.This research was funded by Instituto Puleva de Nutrición (IPN)
Epidemiological and Clinical Complexity of Amoxicillin-Clavulanate- Resistant Escherichia coli
Two hundred twelve patients with colonization/infection due to amoxicillin-clavulanate (AMC)-resistant Escherichia coli were
studied. OXA-1- and inhibitor-resistant TEM (IRT)-producing strains were associated with urinary tract infections, while
OXA-1 producers and chromosomal AmpC hyperproducers were associated with bacteremic infections. AMC resistance in E.
coli is a complex phenomenon with heterogeneous clinical implications
Spanish Multicenter Study of the Epidemiology and Mechanisms of Amoxicillin-Clavulanate Resistance in Escherichia coli
We conducted a prospective multicenter study in Spain to characterize the mechanisms of resistance to amoxicillin-clavu-lanate (AMC) in Escherichia coli. Up to 44 AMC-resistant E. coli isolates (MIC>32/16 g/ml) were collected at each of theseven participant hospitals. Resistance mechanisms were characterized by PCR and sequencing. Molecular epidemiology was studied by pulsed-field gel electrophoresis (PFGE) and by multilocus sequence typing. Overall AMC resistance was 9.3%. The resistance mechanisms detected in the 257 AMC-resistant isolates were OXA-1 production (26.1%), hyperpro-duction of penicillinase (22.6%), production of plasmidic AmpC (19.5%), hyperproduction of chromosomic AmpC(18.3%), and production of inhibitor-resistant TEM (IRT) (17.5%). The IRTs identified were TEM-40 (33.3%), TEM-30(28.9%), TEM-33 (11.1%), TEM-32 (4.4%), TEM-34 (4.4%), TEM-35 (2.2%), TEM-54 (2.2%), TEM-76 (2.2%), TEM-79(2.2%), and the new TEM-185 (8.8%). By PFGE, a high degree of genetic diversity was observed although two well-defined
clusters were detected in the OXA-1-producing isolates: the C1 cluster consisting of 19 phylogroup A/sequence type 88[ST88] isolates and the C2 cluster consisting of 19 phylogroup B2/ST131 isolates (16 of them producing CTX-M-15). Each of the clusters was detected in six different hospitals. In total, 21.8% of the isolates were serotype O25b/phylogroup B2
(O25b/B2). AMC resistance in E. coli is widespread in Spain at the hospital and community levels. A high prevalence of OXA-1 was found. Although resistant isolates were genetically diverse, clonality was linked to OXA-1-producing isolates of the STs 88 and 131. Dissemination of IRTs was frequent, and the epidemic O25b/B2/ST131 clone carried many different
mechanisms of AMC resistance
Smoking among hospitalized patients: a multi-hospital cross sectional study of a widely neglected problem
Introduction: A comprehensive smoking ban was recently enacted for acute-care hospital campuses in Spain. The aim of this study was to assess the prevalence and patterns of smoking among inpatients before and during hospitalization. Methods: Multi-center cross-sectional study was conducted in 13 hospitals in the province of Barcelona, Spain from May 2014 to May 2015. Participants were adults who provided informed consent. The sample size was calculated to be representative of each hospital (prevalence 29.4%, precision ± 5%, error 5%). We approached 1228 subjects, 888 accepted to participate and 170 were replaced (were not available or declined to participate). Final sample comprised 1047 subjects. We used a computer-assisted personal interview system to collect data, including sociodemographic variables and use of tobacco before and during hospitalization. Smoking status was validated with exhaled carbon monoxide. We calculated overall tobacco prevalence and investigated associations with participant and center characteristics. We performed multiple polytomous and multilevel logistic regression analyses to estimate odds ratios (ORs) and 95% confidence intervals (CIs), with adjustments for potential confounders. Results: In all, 20.5% (95% CI: 18.1-23.0) of hospitalized patients were smokers. Smoking was most common among men (aOR=7.47; 95% CI: 4.88-11.43), young age groups (18-64 years), and individuals with primary or less than primary education (aOR=2.76; 95% CI: 1.44-5.28). Of the smokers, 97.2% were daily consumers of whom 44.9% had medium nicotine dependence. Of all smokers, three-quarters expressed a wish to quit, and one-quarter admitted to consuming tobacco during hospitalization. Conclusions: Our findings indicate the need to offer smoking cessation interventions among hospitalized patients in all units and service areas, to avoid infringements and increase patient safety, hospital efficiency, and improve clinical outcomes. Hospitalization represents a promising window for initiating smoking interventions addressed to all patients admitted to smoke-free hospitals, specially after applying a smoke-free campus ban
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