631 research outputs found
In Vitro Plant Regeneration in Conifers: The Role of WOX and KNOX Gene Families
[EN] Conifers are a group of woody plants with an enormous economic and ecological importance.
Breeding programs are necessary to select superior varieties for planting, but they have many
limitations due to the biological characteristics of conifers. Somatic embryogenesis (SE) and de novo
organogenesis (DNO) from in vitro cultured tissues are two ways of plant mass propagation that
help to overcome this problem. Although both processes are difficult to achieve in conifers, they offer
advantages like a great efficiency, the possibilities to cryopreserve the embryogenic lines, and the
ability of multiplying adult trees (the main bottleneck in conifer cloning) through DNO. Moreover, SE
and DNO represent appropriate experimental systems to study the molecular bases of developmental
processes in conifers such as embryogenesis and shoot apical meristem (SAM) establishment. Some
of the key genes regulating these processes belong to the WOX and KNOX homeobox gene families,
whose function has been widely described in Arabidopsis thaliana. The sequences and roles of these
genes in conifers are similar to those found in angiosperms, but some particularities exist, like the
presence of WOXX, a gene that putatively participates in the establishment of SAM in somatic
embryos and plantlets of Pinus pinaster.SIThis research was funded by “Fondo Europeo de Desarrollo Regional” (FEDER)/“Ministerio de Ciencia, Innovación y Universidades—Agencia Estatal de Investigación” (RTA2017-00063-C04-04)
Structure of characteristic Lyapunov vectors in anharmonic Hamiltonian lattices
In this work we perform a detailed study of the scaling properties of Lyapunov vectors (LVs) for two different one-dimensional Hamiltonian lattices: the Fermi-Pasta-Ulam and ?4 models. In this case, characteristic (also called covariant) LVs exhibit qualitative similarities with those of dissipative lattices but the scaling exponents are different and seemingly nonuniversal. In contrast, backward LVs (obtained via Gram-Schmidt orthonormalizations) present approximately the same scaling exponent in all cases, suggesting it is an artificial exponent produced by the imposed orthogonality of these vectors. We are able to compute characteristic LVs in large systems thanks to a "bit reversible" algorithm, which completely obviates computer memory limitations.M.R.B. acknowledges financial support from PROMEP and CONACyT, México, as well as the warm hospitality of
the U.A.E.M. during the first stages of this work. D.P. acknowledges support by CSIC under the Junta de Ampliación de Estudios Programme (JAE-Doc). Financial support from the Ministerio de Ciencia e Innovación (Spain) under Projects No. FIS2009-12964-C05-05 and No. CGL2007-64387/CLI is acknowledged
Prevalence of Intimate Partner Violence in Pregnancy: An Umbrella Review
Background: Intimate partner violence (IPV) is a public health concern, especially during
pregnancy, and needs to be urgently addressed. In order to establish effective actions for the
prevention of IPV during pregnancy, authorities must be aware of the real burden of IPV. This review
aimed to summarize the existing evidence about IPV prevalence during pregnancy worldwide.
Methods: A review of reviews was carried out. All published systematic reviews and meta-analyses
published until October 2020 were identified through PubMed, Scopus, and Web of Science. The main
outcome was the IPV prevalence during pregnancy. Results: A total of 12 systematic reviews were
included in the review, 5 of them including meta-analysis. The quality of the reviews was variable.
Physical IPV during pregnancy showed a wide range (1.6–78%), as did psychological IPV (1.8–67.4%).
Conclusions: Available data about IPV prevalence during pregnancy were of low quality and showed
high figures for physical and psychological IPV. The existing evidence syntheses do not capture the
totality of the worldwide disease burden of IPV in pregnancy.Ministry of Science, Innovation, and Universities of the Spanish Governmen
CO19 168. Impacto de la hipertensión pulmonar en la evolución de los ancianos sometidos a sustitución valvular aórtica
ObjetivoEstudiar la influencia de la hipertensión pulmonar (HTP) en la evolución de los ancianos sometidos a sustitución valvular aórtica (SVA).Material y métodosDesde octubre de 1999 hasta noviembre de 2009, 517 ancianos (rango 70-87 años) fueron sometidos a SVA. Trescientos cincuenta y cinco (68,7%) enfermos (grupo I) tenían hipertensión pulmonar (ligera 157; moderada 149; grave 49) frente a 162 (31,3%) (grupo II) con presiones pulmonares normales. El seguimiento medio fue de 4,3 años.ResultadosLa edad media fue de 76,4±3,9 años. La fibrilación auricular (29,5 vs 5,6%; p=0,001) y la insuficiencia mitral moderada preoperatorias (13,7 vs 5,1%; p=0,003) fueron más frecuentes en el grupo I. La mortalidad hospitalaria fue 4,3%, siendo significativamente superior en los pacientes con HTP (I: 5,7% vs II: 0,8%; p=0,027). Los pacientes con HTP moderada (7,3%) o grave (13,9%) tuvieron una mortalidad significativamente superior a la de los pacientes con HTP ligera (1,7%) (p=0,016). La supervivencia actuarial a los 5 años, de los pacientes dados de alta, aunque superior en los pacientes sin HTP (I: 80,9% vs II: 90,6%; p=0,162), no alcanzó significación. La HTP moderada-grave se asoció de manera independiente a la mortalidad hospitalaria (odds ratio [OR]: 2,07; p=0,015), pero no a una menor supervivencia en el seguimiento.ConclusionesLa HTP moderada-grave es un factor de riesgo independiente de mortalidad hospitalaria en los ancianos sometidos a SVA. Su influencia en la supervivencia a medio plazo es menos clara
Practical approach on frail older patients attended for acute heart failure
Acute heart failure (AHF) is a multi-organ dysfunction syndrome. In addition to known cardiac dysfunction, non-cardiac comorbidity, frailty and disability are independent risk factors of mortality, morbidity, cognitive and functional decline, and risk of institutionalization. Frailty, a treatable and potential reversible syndrome very common in older patients with AHF, increases the risk of disability and other adverse health outcomes. This position paper highlights the need to identify frailty in order to improve prognosis, the risk-benefits of invasive diagnostic and therapeutic procedures, and the definition of older-person-centered and integrated care plans
Aerial mapping and multi-sensors approaches from remote sensing applied to the roman archaeological heritage
This report details the preliminary results of the research focused on Roman archaeological heritage in the Middle Ebro Valley (Spain). The principal objective of this project was to obtain several different readings by means of a UAV equipped with different sensors. Firstly, it has been possible to obtain accurate maps, 3D models and digital elevation models of the site. Secondly, it has been possible to investigate and define archaeological remains still underground, via a new methodology which utilises visible and near-infrared wavelengths
Effects of non-pharmacological conservative treatment on pain, range of motion and physical function in patients with mild to moderate hip osteoarthritis. A systematic review
Objective: The purpose of this review was to identify the effects of non-pharmacological conservative treatment on pain, range of motion and physical function in patients with mild to moderate hip osteoarthritis. Design: A systematic review based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Setting: We searched MEDLINE, PEDro, Scopus and the Cochrane Library databases for randomized controlled trials related to non-pharmacological conservative treatments for hip osteoarthritis with the following keywords: “hip osteoarthritis, ” “therapeutics, ” “physical therapy modalities, ” and “combined physical therapy”. The PEDro scale was used for methodological quality assessment and the Oxford Centre of Evidence-Based Medicine scale was used to assess the level of evidence. Outcomes measures related to pain, hip range of motion and physical function were extracted from these studies. Results: Twelve studies met the inclusion criteria. Most of the studies showed high level of evidence and only two showed low level of evidence. High quality of evidence showed that manual therapy and exercise therapy are effective in improving pain, hip range of motion and physical function. However, high quality studies based on combined therapies showed controversy in their effects on pain, hip range of motion and physical function. Conclusions: Exercise therapy and manual therapy and its combination with patient education provides benefits in pain and improvement in physical function. The effects of combined therapies remain unclear. Further investigation is necessary to improve the knowledge about the effects of non-pharmacological conservative treatments on pain, hip range of motion and physical function
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