La teoría del ciclo como explicación a las crisis económicas

Este trabajo analiza la teoría de ciclos económicos de la Escuela Austriaca de economía y su capacidad predictiva estudiando las principales crisis económicas de los últimos cien años. Los austriacos explican la formación de crisis económicas como el resultado de la intervención de las instituciones en la economía. El argumento principal se basa en la crítica a las políticas monetarias expansivas, lo que influye en los tipos de interés y en las expectativas del mercado de inversores y consumidores. Estos, gracias a la euforia provocada, se animan a invertir en sectores improductivos o con rentabilidad a largo plazo y a aumentar el consumo pidiendo créditos. Esta explicación se fundamenta con la praxeología o ciencia de la acción humana, que utilizan para explicar la economía, y que se centra en los propósitos del ser humano y el camino para su consecución, siendo conscientes de que es complicado prever esas acciones.Grado en Administración y Dirección de Empresa

La influencia de la robótica en la evolución de los puestos de trabajo

Este trabajo analiza la influencia de la robótica en el ámbito laboral, trata de explicar cómo la automatización ha ido introduciéndose en la sociedad y cambiando, en este caso, el mercado laboral. Además, se muestra el futuro de diferentes puestos de trabajo y su evolución en mayor o menor medida con respecto a las tecnologías. El lector podrá comprender mejor la evolución del empleo, ya que, la robótica va a modificar las tareas de los puestos de trabajo actuales evitando las más rutinarias y fomentado el aporte de valor a la empresa. Por otra parte, la tecnología podría suponer un problema a nivel social ya que los trabajadores van a tener que aprender a adaptarse al mercado y muchos de ellos podrían quedar fuera de este. La polarización de los puestos también puede significar una precarización del empleo actual, por lo que las políticas sociales junto con un cambio del concepto de trabajo serán muy importantes para evitar que la robótica excluya a una parte de la población.Grado en Relaciones Laborales y Recursos Humano

Assessment of Quality of Life Following Diagnosis in Patients with Cervicofacial Non-melanoma Skin Cancer

Non-melanoma skin cancer (NMSC) is the most common neoplasm. The characteristics of this disease (location in aesthetically sensitive areas, the appearance of successive tumors during follow-up, and high rates of survival) are such that the concept of health-related quality of life (HRQoL) is of particular importance. The aim of the present study was to describe and analyses patient quality of life following diagnosis with cervicofacial NMSC. A descriptive cross-sectional study was conducted on patients with cervicofacial NMSC, confirmed by skin biopsy. In each case, when the definitive diagnosis of NMSC was established, the patient completed the Skin Cancer Index questionnaire and demographic data, health status, and sun exposure habits were recorded. The study population was composed of 220 patients with histologically confirmed cervicofacial NMSC. The mean score obtained for the Skin Cancer Index questionnaire was 54.1 (SD 21.9), in which the social-aesthetic component had a mean score of 76.7 (SD 26.2), while the emotional component had a mean score of 23 (SD 25.1). Male patients, those with secondary or higher education, and those who had no history of anxiety or depression had significantly higher mean scores for HRQoL. This study demonstrated that the diagnosis of cervicofacial NMSC significantly impacts HRQoL and that certain population groups (women, persons with only primary or no education qualifications, and those a history of anxiety or depression) are more susceptible. The questionnaire scores obtained were lower than those reported in previous studies on this topic and reflect a particularly strong impact on emotional aspects of patient quality of life

Assessment of Quality of Life Following Diagnosis in Patients with Cervicofacial Non-melanoma Skin Cancer

Non-melanoma skin cancer (NMSC) is the most common neoplasm. The characteristics of this disease (location in aesthetically sensitive areas, the appearance of successive tumors during follow-up, and high rates of survival) are such that the concept of health-related quality of life (HRQoL) is of particular importance. The aim of the present study was to describe and analyses patient quality of life following diagnosis with cervicofacial NMSC. A descriptive cross-sectional study was conducted on patients with cervicofacial NMSC, confirmed by skin biopsy. In each case, when the definitive diagnosis of NMSC was established, the patient completed the Skin Cancer Index questionnaire and demographic data, health status, and sun exposure habits were recorded. The study population was composed of 220 patients with histologically confirmed cervicofacial NMSC. The mean score obtained for the Skin Cancer Index questionnaire was 54.1 (SD 21.9), in which the social-aesthetic component had a mean score of 76.7 (SD 26.2), while the emotional component had a mean score of 23 (SD 25.1). Male patients, those with secondary or higher education, and those who had no history of anxiety or depression had significantly higher mean scores for HRQoL. This study demonstrated that the diagnosis of cervicofacial NMSC significantly impacts HRQoL and that certain population groups (women, persons with only primary or no education qualifications, and those a history of anxiety or depression) are more susceptible. The questionnaire scores obtained were lower than those reported in previous studies on this topic and reflect a particularly strong impact on emotional aspects of patient quality of life

Rúbrica para la evaluación de la habilidad de determinar la presión arterial

Podeu consultar la Vuitena trobada de professorat de Ciències de la Salut completa a: http://hdl.handle.net/2445/66524La determinación de la presión arterial (Pa) forma parte de la atención farmacéutica tanto desde el punto de vista del cribado de la hipertensión en la población general como en el seguimiento del enfermo hipertenso1. Por ello, la habilidad de determinar la Pa constituye uno de los objetivos de aprendizaje del grado de Farmacia de la Universitat de Barcelona y se desarrolla en las clases prácticas de la asignatura de Fisiología y Fisiopatología II. En cada curso académico, la práctica se enseña durante 2 horas a unos 350 alumnos repartidos en 17-18 grupos de docencia. Días después de realizar la práctica, el profesor evalúa el grado de adquisición de dicha habilidad por parte del estudiante, el cual realiza la medición de Pa a un compañero. Si bien el guión de prácticas recoge las fases a seguir para la determinación correcta de la Pa y que son objeto de evaluación, el profesorado implicado en la evaluación otorgaba una puntuación global a la habilidad..

Los nuevos desafíos de la contabilidad

n.d.Fil: Suardi, Diana. Facultad de Ciencias Económicas y Estadística - Universidad Nacional de Rosario - Argentin

Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA

The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and B-cell precursor acute lymphoblastic leukemia (ALL) Philadelphia (Ph)-positive patients. In this study, we present a novel DNA-based next-generation sequencing (NGS) methodology for KD ABL1 mutation detection and monitoring with a 1.0E-4 sensitivity. This approach was validated with a well-stablished RNA-based nested NGS method. The correlation of both techniques for the quantification of ABL1 mutations was high (Pearson r = 0.858, p < 0.001), offering DNA-DeepNGS a sensitivity of 92% and specificity of 82%. The clinical impact was studied in a cohort of 129 patients (n = 67 for CML and n = 62 for B-ALL patients). A total of 162 samples (n = 86 CML and n = 76 B-ALL) were studied. Of them, 27 out of 86 harbored mutations (6 in warning and 21 in failure) for CML, and 13 out of 76 (2 diagnostic and 11 relapse samples) did in B-ALL patients. In addition, in four cases were detected mutation despite BCR::ABL1 < 1%. In conclusion, we were able to detect KD ABL1 mutations with a 1.0E-4 sensitivity by NGS using DNA as starting material even in patients with low levels of disease

Monitorización del consumo de sustancias de abuso legales e ilegales en España a través de las aguas residuales en el marco de la red ESAR-Net

Trabajo presentado en el 4th Congreso Internacional y XLIX Jornadas Nacionales de Socidrogalcohol - VIII Congreso Nacional Patología Bio-Psicosocial, celebrado en Tenerife del 06 al 08 de octubre de 2022

Detection of kinase domain mutations in BCR::ABL1 leukemia by ultra-deep sequencing of genomic DNA

The screening of the BCR::ABL1 kinase domain (KD) mutation has become a routine analysis in case of warning/failure for chronic myeloid leukemia (CML) and B-cell precursor acute lymphoblastic leukemia (ALL) Philadelphia (Ph)-positive patients. In this study, we present a novel DNA-based next-generation sequencing (NGS) methodology for KD ABL1 mutation detection and monitoring with a 1.0E−4 sensitivity. This approach was validated with a well-stablished RNA-based nested NGS method. The correlation of both techniques for the quantification of ABL1 mutations was high (Pearson r = 0.858, p < 0.001), offering DNA-DeepNGS a sensitivity of 92% and specificity of 82%. The clinical impact was studied in a cohort of 129 patients (n = 67 for CML and n = 62 for B-ALL patients). A total of 162 samples (n = 86 CML and n = 76 B-ALL) were studied. Of them, 27 out of 86 harbored mutations (6 in warning and 21 in failure) for CML, and 13 out of 76 (2 diagnostic and 11 relapse samples) did in B-ALL patients. In addition, in four cases were detected mutation despite BCR::ABL1 < 1%. In conclusion, we were able to detect KD ABL1 mutations with a 1.0E−4 sensitivity by NGS using DNA as starting material even in patients with low levels of disease.Tis project was funded in part by CRIS CANCER FOUNDATION