Gait Analysis of Horses for Lameness Detection with Radar Sensors

This paper presents the preliminary investigation of the use of radar signatures to detect and assess lameness of horses and its severity. Radar sensors in this context can provide attractive contactless sensing capabilities, as a complementary or alternative technology to the current techniques for lameness assessment using video-graphics and inertial sensors attached to the horses' body. The paper presents several examples of experimental data collected at the Weipers Centre Equine Hospital at the University of Glasgow, showing the micro- Doppler signatures of horses and preliminary results of their analysis

The organic waste gold rush: optimising resource recovery in the UK bioeconomy

The use of organic waste in the bioeconomy has the potential to contribute towards the UK’s strategic goals of clean growth, resource security and reducing use of fossil fuels. While the reduction of avoidable organic waste remains a priority, a number of waste streams are likely to persist and could provide a significant feedstock for the UK bioeconomy. The greatest environmental, social and economic benefits of resource recovery from organic wastes are associated with the displacement of fossil fuel derived chemicals and materials, and the combined products of nutrients and energy from anaerobic digestion. Organic wastes offer multiple resources that can be exploited most efficiently by technologies working in synergy with each other. Investments into different options for using organic wastes are driven by government policy and resource demand, in addition to technology readiness. Policy and regulations should encourage industrial synergies and an increase in the diversity of resources recovered from organic waste in order to be able to respond to future resource demands

The Dwarf Irregular Galaxy UGC 7636 Exposed: Stripping At Work In The Virgo Cluster

We present the results of optical spectroscopy of a newly discovered H II region residing in the H I gas cloud located between the dwarf irregular galaxy UGC 7636 and the giant elliptical galaxy NGC 4472 in the Virgo Cluster. By comparing UGC 7636 with dwarf irregular galaxies in the field, we show that the H I cloud must have originated from UGC 7636 because (1) the oxygen abundance of the cloud agrees with that expected for a galaxy with the blue luminosity of UGC 7636, and (2) M_{H I}/L_B for UGC 7636 becomes consistent with the measured oxygen abundance of the cloud if the H I mass of the cloud is added back into UGC 7636. It is likely that tides from NGC 4472 first loosened the H I gas, after which ram-pressure stripping removed the gas from UGC 7636.Comment: 12 pages, 2 eps figures (AASTeX 5.0); accepted for publication in ApJ Letter

Toward vicarious calibration of microwave remote-sensing satellites in arid environments

The Soil Moisture and Ocean Salinity (SMOS) satellite marks the commencement of dedicated global surface soil moisture missions, and the first mission to make passive microwave observations at L-band. On-orbit calibration is an essential part of the instrument calibration strategy, but on-board beam-filling targets are not practical for such large apertures. Therefore, areas to serve as vicarious calibration targets need to be identified. Such sites can only be identified through field experiments including both in situ and airborne measurements. For this purpose, two field experiments were performed in central Australia. Three areas are studied as follows: 1) Lake Eyre, a typically dry salt lake; 2) Wirrangula Hill, with sparse vegetation and a dense cover of surface rock; and 3) Simpson Desert, characterized by dry sand dunes. Of those sites, only Wirrangula Hill and the Simpson Desert are found to be potentially suitable targets, as they have a spatial variation in brightness temperatures of <4 K under normal conditions. However, some limitations are observed for the Simpson Desert, where a bias of 15 K in vertical and 20 K in horizontal polarization exists between model predictions and observations, suggesting a lack of understanding of the underlying physics in this environment. Subsequent comparison with model predictions indicates a SMOS bias of 5 K in vertical and 11 K in horizontal polarization, and an unbiased root mean square difference of 10 K in both polarizations for Wirrangula Hill. Most importantly, the SMOS observations show that the brightness temperature evolution is dominated by regular seasonal patterns and that precipitation events have only little impact

Cellular bases for human atrial fibrillation

Atrial fibrillation (AF) causes substantial morbidity and mortality. It may be triggered and sustained by either reentrant or nonreentrant electrical activity. Human atrial cellular refractory period is shortened in chronic AF, likely aiding reentry. The ionic and molecular mechanisms are not fully understood and may include increased inward rectifier K&lt;sup&gt;+&lt;/sup&gt; current and altered Ca&lt;sup&gt;2+&lt;/sup&gt; handling. Heart failure, a major cause of AF, may involve arrhythmogenic atrial electrical remodeling, but the pattern is unclear in humans. Beta-blocker therapy prolongs atrial cell refractory period; a potentially antiarrhythmic influence, but the ionic and molecular mechanisms are unclear. The search for drugs to suppress AF without causing ventricular arrhythmias has been aided by basic studies of cellular mechanisms of AF. It remains to be seen whether such drugs will improve patient treatment

Chandra and HST observations of gamma-ray blazars: comparing jet emission at small and large scales

We present new Chandra and HST data for four gamma-ray blazars selected on the basis of radio morphology with the aim of revealing X-ray and optical emission from their jets at large scales. All the sources have been detected. Spectral Energy Distributions of the large scale jets are obtained as well as new X-ray spectra for the blazar cores. Modeling for each object the core (sub-pc scale) and large-scale (>100 kpc) jet SEDs, we derive the properties of the same jet at the two scales. The comparison of speeds and powers at different scales supports a simple scenario for the dynamics and propagation of high power relativistic jets.Comment: Accepted for publication in Ap

Determining the Cosmic Distance Scale from Interferometric Measurements of the Sunyaev-Zel'dovich Effect

We determine the distances to 18 galaxy clusters with redshifts ranging from z~0.14 to z~0.78 from a maximum likelihood joint analysis of 30 GHz interferometric Sunyaev-Zel'dovich effect (SZE) and X-ray observations. We model the intracluster medium (ICM) using a spherical isothermal beta model. We quantify the statistical and systematic uncertainties inherent to these direct distance measurements, and we determine constraints on the Hubble parameter for three different cosmologies. These distances imply a Hubble constant of 60 (+4, -4) (+13, -18) km s-1 Mpc-1 for an Omega_M = 0.3, Omega_Lambda = 0.7 cosmology, where the uncertainties correspond to statistical followed by systematic at 68% confidence. With a sample of 18 clusters, systematic uncertainties clearly dominate. The systematics are observationally approachable and will be addressed in the coming years through the current generation of X-ray satellites (Chandra & XMM-Newton) and radio observatories (OVRO, BIMA, & VLA). Analysis of high redshift clusters detected in future SZE and X-ray surveys will allow a determination of the geometry of the universe from SZE determined distances.Comment: ApJ Submitted; 40 pages, 9 figures (fig 3 B&W for size constraint), 13 tables, uses emulateapj5 styl

Effects of data selection on the assimilation of AIRS data

The Atmospheric InfraRed Sounder (AIRS), flying aboard NASA's Earth Observing System (EOS) Aqua satellite with the Advanced Microwave Sounding Unit-A (AMSU-A), has been providing data for use in numerical weather prediction (NWP) and data assimilation systems (DAS) for over three years. The full AIRS data set is currently not transmitted in near-real-time (NRT) to the NWP centers. Instead, data sets with reduced spatial and spectral information are produced and made available in NRT. In this paper, we evaluate the use of different channel selections and error specifications. We achieved significant positive impact from the Aqua AIRS/AMSU-A combination in both hemispheres during our experimental time period of January 2003. The best results were obtained using a set of 156 channels that did not include any in the 6.7micron water vapor band. The latter have a large influence on both temperature and humidity analyses. If observation and background errors are not properly specified, the partitioning of temperature and humidity information from these channels will not be correct, and this can lead to a degradation in forecast skill. We found that changing the specified channel errors had a significant effect on the amount of data that entered into the analysis as a result of quality control thresholds that are related to the errors. However, changing the channel errors within a relatively small window did not significantly impact forecast skill with the 155 channel set. We also examined the effects of different types of spatial data reduction on assimilated data sets and NWP forecast skill. Whether we picked the center or the warmest AIRS pixel in a 3x3 array affected the amount of data ingested by the analysis but had a negligible impact on the forecast skill

Spitzer Observations of Cold Dust Galaxies

We combine new Spitzer Space Telescope observations in the mid- and far-infrared with SCUBA 850 micron observations to improve the measurement of dust temperatures, masses and luminosities for 11 galaxies of the SCUBA Local Universe Galaxy Survey (SLUGS). By fitting dust models we measure typical dust masses of 10E7.9 M_sol and dust luminosities of ~ 10E10 L_sol, for galaxies with modest star formation rates. The data presented in this paper combined with previous observations show that cold dust is present in all types of spiral galaxies and is a major contributor to their total luminosity. Because of the lower dust temperature of the SCUBA sources measured in this paper, they have flatter Far-IR nu F_nu(160um)/nu F_nu(850um) slopes than the larger Spitzer Nearby Galaxies Survey (SINGS), the sample that provides the best measurements of the dust properties of galaxies in the nearby universe. The new data presented here added to SINGS extend the parameter space that is well covered by local galaxies, providing a comprehensive set of templates that can be used to interpret the observations of nearby and distant galaxies.Comment: Accepted by A.J. 16 pages, 10 figures, 7 tables. High resolution version at http://mips.as.arizona.edu/~cnaw/slugs_hires.pd

Face valid phenotypes in a mouse model of the most common mutation in EEF1A2 related neurodevelopmental disorder, E122K

De novo heterozygous missense mutations in EEF1A2, encoding neuromuscular translation-elongation factor eEF1A2, are associated with developmental and epileptic encephalopathies. We used CRISPR/Cas9 to recapitulate the most common mutation, E122K, in mice. Although E122K heterozygotes were not observed to have convulsive seizures, they exhibited frequent electrographic seizures and EEG abnormalities, transient early motor deficits and growth defects. Both E122K homozygotes and Eef1a2-null mice developed progressive motor abnormalities, with E122K homozygotes reaching humane endpoints by P31. The null phenotype is driven by progressive spinal neurodegeneration; however, no signs of neurodegeneration were observed in E122K homozygotes. The E122K protein was relatively stable in neurons yet highly unstable in skeletal myocytes, suggesting that the E122K/E122K phenotype is instead driven by loss of function in muscle. Nevertheless, motor abnormalities emerged far earlier in E122K homozygotes than in nulls, suggesting a toxic gain of function and/or a possible dominant-negative effect. This mouse model represents the first animal model of an EEF1A2 missense mutation with face-valid phenotypes and has provided mechanistic insights needed to inform rational treatment design.</p