To Bind or Not to Bind Collectively? Decomposition of Bargained Wage Differences Using Counterfactual Distributions

Collective bargaining agreements still play an important role in the German wage setting system. Both existing theoretical and empirical studies find that collective bargaining leads to higher wages compared to individually agreed ones. However, the impact of collective bargaining on the wage level may be very different along the wage distribution. As unions aim at compressing the wage distribution, one might expect that for covered workers' wages in the lower part of the distribution workers' individual characteristics may be less important than the coverage by a collective contract. In contrast, the relative importance of workers' individual characteristics may rise in the upper part of the wage distribution, whereas the overall wage difference might decline. Using the newly available German Structure of Earnings Survey (GSES) 1995 and 2001, a cross-sectional linked employer-employee-dataset from German official statistics, this study analyses the difference between collectively and individually agreed wages using a Machado/Mata (2005) decomposition type technique.collective bargaining; wage structure; wage decomposition; quantile regression

To bind or not to bind collectively? : decomposition of bargained wage differences using counterfactual distributions

Collective bargaining agreements still play an important role in the German wage setting system. Both existing theoretical and empirical studies find that collective bargaining leads to higher wages compared to individually agreed ones. However, the impact of collective bargaining on the wage level may be very different along the wage distribution. As unions aim at compressing the wage distribution, one might expect that for covered workers? wages in the lower part of the distribution workers? individual characteristics may be less important than the coverage by a collective contract. In contrast, the relative importance of workers? individual characteristics may rise in the upper part of the wage distribution, whereas the overall wage difference might decline. Using the newly available German Structure of Earnings Survey (GSES) 1995 and 2001, a cross-sectional linked employer-employee-dataset from German official statistics, this study analyses the difference between collectively and individually agreed wages using a Machado/Mata (2005) decomposition type technique.Kollektive Tarifverträge spielen immer noch eine wichtige Rolle im deutschen Lohnfindungssystem. Sowohl theoretische als auch empirische Studien kommen zu dem Ergebnis, dass kollektive Tarifverhandlungen zu vergleichsweise höheren Löhnen führen als individuelle Lohnverhandlungen. Jedoch kann der Einfluss von kollektiven Tarifverhandlungen auf das Lohnniveau innerhalb von Lohnverteilungen stark variieren. Da Gewerkschaften das Ziel verfolgen, die Streuung innerhalb der Lohnverteilung möglichst gering zu halten, ist anzunehmen, dass die Löhne von tarifvertraglich gebundenen Arbeitnehmern im unteren Teil der Verteilung weniger stark von deren Leistungsmerkmalen abhängig sind. Vielmehr macht sich hier der kollektivvertragliche Einfluss auf die Löhne bemerkbar. Dagegen sollte die relative Bedeutung der individuellen Leistungsmerkmale der Arbeitnehmer im oberen Teil der Lohnverteilung zunehmen, wohingegen die absolute Lohndifferenz in diesem Bereich fällt. Mit Hilfe der erst seit kurzem verfügbaren Gehalts- und Lohnstrukturerhebung (GLS, Wellen 1995 und 2001) wird in der vorliegenden Analyse der Unterschied zwischen kollektiv verhandelten und indivduell vereinbarten Löhnen unter Verwendung einer Machado/Mata (2005)-Zerlegungstechnik beleuchtet

Oral anticoagulants - a frequent challenge for the emergency management of acute ischemic stroke

Background: The emergency management of patients with acute ischemic stroke (IS) using oral anticoagulants (OAC) represents a great challenge. Effective anticoagulation predisposes to bleeding and represents a contraindication for systemic thrombolysis. However, patients on OAC can receive intravenous thrombolysis with recombinant tissue-type plasminogen activator if the international normalized ratio (INR) does not exceed 1.7, but data regarding the risk of hemorrhagic complications are highly controversial. Neurointerventional recanalization of intracranial artery occlusion represents an alternative option in OAC patients with acute IS. The proportion of OAC users among consecutive patients who suffer from acute IS or transient ichemic attacks (TIA) is unknown. Methods: A prospective observational study, consecutively enrolling all patients with IS or TIA admitted to our neurological emergency room (ER), was performed between August 2009 and February 2011. Basic demographic variables, present use of OAC, severity of stroke, cardiovascular risk factors, INR values and the symptom onset to presentation time were recorded. In IS patients on OAC presenting within 4.5 h after symptom onset, management was analyzed. In thrombolysed IS patients, bleeding events were documented. Outcome was assessed after 3 months

Actin/microtubule crosstalk during platelet biogenesis in mice is critically regulated by Twinfilin1 and Cofilin1

Rearrangements of the microtubule (MT) and actin cytoskeleton are pivotal for platelet biogenesis. Hence, defects in actin- or MT-regulatory proteins are associated with platelet disorders in humans and mice. Previous studies in mice revealed that loss of the actin-depolymerizing factor homology (ADF-H) protein Cofilin1 (Cof1) in megakaryocytes (MKs) results in a moderate macrothrombocytopenia but normal MK numbers, whereas deficiency in another ADF-H protein, Twinfilin1 (Twf1), does not affect platelet production or function. However, recent studies in yeast have indicated a critical synergism between Twf1 and Cof1 in the regulation of actin dynamics. We therefore investigated platelet biogenesis and function in mice lacking both Twf1 and Cof1 in the MK lineage. In contrast to single deficiency in either protein, Twf1/Cof1 double deficiency (DKO) resulted in a severe macrothrombocytopenia and dramatically increased MK numbers in bone marrow and spleen. DKO MKs exhibited defective proplatelet formation in vitro and in vivo as well as impaired spreading and altered assembly of podosome-like structures on collagen and fibrinogen in vitro. These defects were associated with aberrant F-actin accumulation and, remarkably, the formation of hyperstable MT, which appears to be caused by dysregulation of the actin- and MT-binding proteins mDia1 and adenomatous polyposis coli. Surprisingly, the mild functional defects described for Cof1-deficient platelets were only slightly aggravated in DKO platelets suggesting that both proteins are largely dispensable for platelet function in the peripheral blood. In summary, these findings reveal critical redundant functions of Cof1 and Twf1 in ensuring balanced actin/microtubule crosstalk during thrombopoiesis in mice and possibly humans.Peer reviewe

Maine EPSCoR, vol. 1, issue 1

The University of Maine recently gained Carnegie R1 status, a level of recognition that speaks to the quality and scale of research happening at Maine’s land grant, sea grant, and space grant institution, and across the state as a whole. Research institutes, centers and labs established because of NSF EPSCoR RII Track-1 grants have created a significant and lasting impact in Maine. These entities include the Advanced Structures and Composites Center, Frontier Institute for Research in Sensor Technologies, Forest Bioproducts Research Institute, and Mitchell Center for Sustainability Solutions, which have generated over 500 million dollars in new R&D funding for the state following the completion of their RII Track-1 support. Maine EPSCoR’s current NSF EPSCoR RII Track-1 grant, Maine-eDNA, is set to embark on a full field season with work occurring throughout the state. We recognize the researchers, staff, graduate students, and undergraduate students who continue to actively participate in this work. Their effort and resilience in the face of uncertain and changing circumstances is inspiring and makes real contributions in our efforts to expand educational opportunities in STEM, drive workforce development, and strengthen research capacity in the state of Maine

Air pollution trends in the EMEP region between 1990 and 2012

The present report synthesises the main features of the evolution over the 1990-2012 time period of the concentration and deposition of air pollutants relevant in the context of the Convention on Long-range Transboundary Air Pollution: (i) ozone, (ii) sulfur and nitrogen compounds and particulate matter, (iii) heavy metals and persistent organic pollutants. It is based on observations gathered in State Parties to the Convention within the EMEP monitoring network of regional background stations, as well as relevant modelling initiatives. Joint Report of: EMEP Task Force on Measurements and Modelling (TFMM), Chemical Co-ordinating Centre (CCC), Meteorological Synthesizing Centre-East (MSC-E), Meteorological Synthesizing Centre-West (MSC-W)

Sex difference and intra-operative tidal volume: Insights from the LAS VEGAS study

BACKGROUND: One key element of lung-protective ventilation is the use of a low tidal volume (VT). A sex difference in use of low tidal volume ventilation (LTVV) has been described in critically ill ICU patients.OBJECTIVES: The aim of this study was to determine whether a sex difference in use of LTVV also exists in operating room patients, and if present what factors drive this difference.DESIGN, PATIENTS AND SETTING: This is a posthoc analysis of LAS VEGAS, a 1-week worldwide observational study in adults requiring intra-operative ventilation during general anaesthesia for surgery in 146 hospitals in 29 countries.MAIN OUTCOME MEASURES: Women and men were compared with respect to use of LTVV, defined as VT of 8 ml kg-1 or less predicted bodyweight (PBW). A VT was deemed 'default' if the set VT was a round number. A mediation analysis assessed which factors may explain the sex difference in use of LTVV during intra-operative ventilation.RESULTS: This analysis includes 9864 patients, of whom 5425 (55%) were women. A default VT was often set, both in women and men; mode VT was 500 ml. Median [IQR] VT was higher in women than in men (8.6 [7.7 to 9.6] vs. 7.6 [6.8 to 8.4] ml kg-1 PBW, P < 0.001). Compared with men, women were twice as likely not to receive LTVV [68.8 vs. 36.0%; relative risk ratio 2.1 (95% CI 1.9 to 2.1), P < 0.001]. In the mediation analysis, patients' height and actual body weight (ABW) explained 81 and 18% of the sex difference in use of LTVV, respectively; it was not explained by the use of a default VT.CONCLUSION: In this worldwide cohort of patients receiving intra-operative ventilation during general anaesthesia for surgery, women received a higher VT than men during intra-operative ventilation. The risk for a female not to receive LTVV during surgery was double that of males. Height and ABW were the two mediators of the sex difference in use of LTVV.TRIAL REGISTRATION: The study was registered at Clinicaltrials.gov, NCT01601223