A Note on the Use of Marketing Research by Small Businesses

There  is no question  that timely  and accurate information  is as valuable  to small business decision makers as it is  to decision makers in large organizations. Interestingly though, evidence exists that small businesses make little use of (Oumlil, 1989; Hall, Anglin,  and Elliott, 1997; McDaniel and Parasuraman, 1986), and place limited value on (Brush, 1992; Callahan and Cassar, 1995), marketing research -- the very discipline capable of providing this valuable information

Origin and Evolution of Dolostone in the Middle Cambrian Langston Formation, Northern Utah

Six major generations of dolomite are present within the Cambrian Langston Formation in the Wellsville Mountains and Bear River Range of northern Utah. Identification of dolomite generations and delineation of their relative sequences are based on normal light petrography, cathodoluminescence, staining, chemistry, inferred burial history, and deformation features. The earliest stage is believed to be Middle to Late Cambrian in age. The presence of dolomite rhombs and dolomitized echinoid fragments and peloids suggests that this stage probably formed under sabkha reflux conditions. Extensive nonferroan, polymodal, nonplanar ( xenotopic ) dolomite formed next under confined mixing zone conditions. A succeeding generation of pervasive ferroan, polymodal, nonplanar dolomite formed upon exposure to evolved confined mixing zone waters or fluids derived from basin compaction. Subsequent neomorphism of these two nonplanar stages to nonferroan and ferroan saddle dolomites occurred with increased burial. The final stage of dolomitization is confined to dolomite-filled veins and an orthodolospar probably fanned from fluids associated with Tertiary Basin and Range faulting. Thus, there are at least six major types of dolomite within the Langston Formation. Spatial distribution and intensity of the early-formed dolomite facies, as revealed by fence diagrams, are postulated to be functions of changes in permeability, hydrodynamic dispersion, water chemistry, and concomitant variations in length of the induction ix stages

Development of unsteady aerodynamic analyses for turbomachinery aeroelastic and aeroacoustic applications

Theoretical analyses and computer codes are being developed for predicting compressible unsteady inviscid and viscous flows through blade rows. Such analyses are needed to determine the impact of unsteady flow phenomena on the structural durability and noise generation characteristics of turbomachinery blading. Emphasis is being placed on developing analyses based on asymptotic representations of unsteady flow phenomena. Thus, flow driven by small-amplitude unsteady excitations in which viscous effects are concentrated in thin layers are being considered. The resulting analyses should apply in many practical situations, lead to a better understanding of the relevent physics, and they will be efficient computationally, and therefore, appropriate for aeroelastic and aeroacoustic design applications. Under the present phase (Task 3), the effort was focused on providing inviscid and viscid prediction capabilities for subsonic unsteady cascade flows

Defining the Destruction Box: Understanding How the APC Recognizes Its Substrates

Cell division is the process by which mother cells give rise to two genetically identical daughter cells. All cells have protein networks to ensure that cell division is completed correctly because mistakes during cell division may cause diseases. The Anaphase-promoting complex (APC) is an important regulatory enzyme that ensures successful completion of mitosis. It acts by removing inhibitors of chromosomal segregation and cytokinesis, as well as other important cell division regulators. Existing chemotherapies, like taxol, act by indirectly inhibiting APC function. This makes APC a potential target for new cancer chemotherapies. However, designing APC inhibitors is challenging because how APC interacts with its substrates is not fully understood. What is currently known is that APC recognizes a short linear sequence containing R-x-x-L, called the destruction box (D-box). A D-box is needed for efficient proteolysis of most APC substrates, but what makes a functional D-box is still unclear. The goal of my project is to define the minimal functional D-box using an artificial reporter substrate containing the known D-box motif from the budding yeast APC substrate Fin1. To accomplish this goal, reporter expression plasmids are mutated and the stability of the mutant proteins are measured and compared using a cycloheximide chase assay. Any mutation in the D-box will cause slower decay in the immunoblotting signal for the reporter substrate after protein synthesis is terminated. By defining the minimal functional D-box, we can understand how APC interacts with its substrates, helping the development of chemotherapy drugs to kill cancer cells

Organizational Purchasing Theory: A Review and Assessment

Mark C. Hall is an Associate Professor in the Department of Marketing at Mankato State University. C.P. Rao is University Professor in the Department of Marketing at the University of Arkansas. Kevin M. Elliott is an Associate Professor in the Department of Marketing at Mankato State University

Student Technology Readiness And Its Impact On Cultural Competency

The creation of an effective learning environment requires cultural competency – the ability to interact effectively with people of different cultures.  Cultural competency means knowing and understanding the people that you serve. This study compares American and Chinese student’s readiness and willingness to use innovative technology by assessing their technology readiness through the use of the Technology Readiness Index (Parasuraman, 2000).  The findings show that Chinese students exhibit higher levels of discomfort and insecurity, and lower levels of optimism and innovativeness with regard to using new technology.  Implications for cross-cultural technology-based learning environments are also provided

Similarity Metrics for Closed Loop Dynamic Systems

To what extent and in what ways can two closed-loop dynamic systems be said to be "similar?" This question arises in a wide range of dynamic systems modeling and control system design applications. For example, bounds on error models are fundamental to the controller optimization with modern control design methods. Metrics such as the structured singular value are direct measures of the degree to which properties such as stability or performance are maintained in the presence of specified uncertainties or variations in the plant model. Similarly, controls-related areas such as system identification, model reduction, and experimental model validation employ measures of similarity between multiple realizations of a dynamic system. Each area has its tools and approaches, with each tool more or less suited for one application or the other. Similarity in the context of closed-loop model validation via flight test is subtly different from error measures in the typical controls oriented application. Whereas similarity in a robust control context relates to plant variation and the attendant affect on stability and performance, in this context similarity metrics are sought that assess the relevance of a dynamic system test for the purpose of validating the stability and performance of a "similar" dynamic system. Similarity in the context of system identification is much more relevant than are robust control analogies in that errors between one dynamic system (the test article) and another (the nominal "design" model) are sought for the purpose of bounding the validity of a model for control design and analysis. Yet system identification typically involves open-loop plant models which are independent of the control system (with the exception of limited developments in closed-loop system identification which is nonetheless focused on obtaining open-loop plant models from closed-loop data). Moreover the objectives of system identification are not the same as a flight test and hence system identification error metrics are not directly relevant. In applications such as launch vehicles where the open loop plant is unstable it is similarity of the closed-loop system dynamics of a flight test that are relevant

Conservation of long-range synteny and microsynteny between the genomes of two distantly related nematodes

BACKGROUND: Comparisons between the genomes of the closely related nematodes Caenorhabditis elegans and Caenorhabditis briggsae reveal high rates of rearrangement, with a bias towards within-chromosome events. To assess whether this pattern is true of nematodes in general, we have used genome sequence to compare two nematode species that last shared a common ancestor approximately 300 million years ago: the model C. elegans and the filarial parasite Brugia malayi. RESULTS: An 83 kb region flanking the gene for Bm-mif-1 (macrophage migration inhibitory factor, a B. malayi homolog of a human cytokine) was sequenced. When compared to the complete genome of C. elegans, evidence for conservation of long-range synteny and microsynteny was found. Potential C. elegans orthologs for II of the 12 protein-coding genes predicted in the B. malayi sequence were identified. Ten of these orthologs were located on chromosome I, with eight clustered in a 2.3 Mb region. While several, relatively local, intrachromosomal rearrangements have occurred, the order, composition, and configuration of two gene clusters, each containing three genes, was conserved. Comparison of B. malayi BAC-end genome survey sequence to C. elegans also revealed a bias towards intrachromosome rearrangements. CONCLUSIONS: We suggest that intrachromosomal rearrangement is a major force driving chromosomal organization in nematodes, but is constrained by the interdigitation of functional elements of neighboring genes

The X-ray Spectrum and Spectral Energy Distribution of FIRST J155633.8+351758: a LoBAL Quasar with a Probable Polar Outflow

We report the results of a new 60 ks Chandra X-ray Observatory Advanced CCD Imaging Spectrometer S-array (ACIS-S) observation of the reddened, radio-selected, highly polarized `FeLoBAL' quasar FIRST J1556+3517. We investigated a number of models of varied sophistication to fit the 531-photon spectrum. These models ranged from simple power laws to power laws absorbed by hydrogen gas in differing ionization states and degrees of partial covering. Preferred fits indicate that the intrinsic X-ray flux is consistent with that expected for quasars of similarly high luminosity, i.e., an intrinsic, dereddened and unabsorbed optical to X-ray spectral index of -1.7. We cannot tightly constrain the intrinsic X-ray power-law slope, but find indications that it is flat (photon index Gamma = 1.7 or flatter at a >99% confidence for a neutral hydrogen absorber model). Absorption is present, with a column density a few times 10^23 cm^-2, with both partially ionized models and partially covering neutral hydrogen models providing good fits. We present several lines of argument that suggest the fraction of X-ray emissions associated with the radio jet is not large. We combine our Chandra data with observations from the literature to construct the spectral energy distribution of FIRST J1556+3517 from radio to X-ray energies. We make corrections for Doppler beaming for the pole-on radio jet, optical dust reddening, and X-ray absorption, in order to recover a probable intrinsic spectrum. The quasar FIRST J1556+3517 seems to be an intrinsically normal radio-quiet quasar with a reddened optical/UV spectrum, a Doppler-boosted but intrinsically weak radio jet, and an X-ray absorber not dissimilar from that of other broad absorption line quasars.Comment: to be published in MNRA