Transcatheter Pulmonary Valve-in-Valve Implantation due to Severe Valve Stenosis Following Bioprosthetic Pulmonary Valve Replacement Degeneration

Transcatheter pulmonary valve-in-valve implantation (TPVI) is a rare procedure consisting of the implantation of a new valve inside the degenerated old pulmonary valve (PV). We present a distinctive case of a patient undergoing the procedure, following degeneration of a previously implanted bioprosthetic PV replacement

THE USE OF PERIPHERALLY INSERTED CENTRAL CATHETER (PICC) IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES – A SINGLE CENTER EXPERIENCE

Cilj. Prikazati vlastita iskustva s upotrebom periferno uvedenoga centralnog venskog katetera (PICC) u bolesnika sa zloćudnim hematološkim bolestima. Metode. U razdoblju od 2009. do 2012. godine postavljeno je ukupno 105 PICC-ova kod 90 bolesnika. Bolesnici s ne-Hodgkinovim limfomima na terapiji DA-EPOCH-om čine gotovo 40% svih bolesnika. Rezultati. Ukupan broj dana s PICC-om je 14.781, a medijan vremena s PICC-om je 129 dana (raspon 8 – 570 dana). Malpozicija PICC-a zabilježena je u 12 bolesnika (11,4%) i u svim slučajevima PICC je uspješno reponiran ili ponovo postavljen. Kod 39 bolesnika (37%) PICC je izvađen prije završetka liječenja: zbog sumnje na infekciju ili dokazane infekcije kod 30 bolesnika (29%; 2,03 na 1000 dana s PICC-om), tromboze vezane uz PICC kod četiri bolesnika (3,8%); okluzija lumena PICC-a kod dva bolesnika, slučajno izvučeni kateteri kod dva bolesnika te sumnja na tromboemboliju kod jedne bolesnice. Zaključak. PICC je siguran i praktičan dugotrajni venski put kod bolesnika sa zloćudnim hematološkim bolestima.Aim. In this study we presented our experience with peripherally inserted central venous catheter (PICC) in patients with hematological malignancies. Methods. In the period from 2009 to 2012, a total of 105 PICCs were inserted in 90 patients. Patients with Non-Hodgkin lymphoma treated with DA-EPOCH comprised almost 40% of the cohort. Results. The total PICC in-dwell time was 14781 days with a median of 129 days (range 8–570 days). Malposition of the PICC occurred in 12 patients (11.4%) with a successful reposition or re-insertion. In 39 patients (37%) PICC was removed before the end of treatment due to suspected or proven infection (30 patients, 29%; 2.03 per 1000 PICC days), thrombosis associated with PICC in four patients (3.8%), occlusion of the PICC (two patients), misplaced catheter (two patients), and suspected thromboembolism in a single patient. Conclusion. PICC is a safe and convenient long-term venous access in patients with hematological malignancies

Revitalization of the Croatian economy caused by the COVID-19 pandemic with an emphasis on the agricultural sector

Bolesti koje se pojave utječu uvelike na ljudski život, ali ne samo na njega već i na cjelokupno funkcioniranje države u kojoj on biva. Gospodarska kriza izazvana korona virusom Covid-19 jedinstvena je u dosadašnjoj ekonomskoj povijesti po načinu i brzini nastanka, globalnom obuhvatu i posljedicama. Nijedna dosadašnja ekonomska kriza nije nastupila tako brzo s dubokim padom gospodarskih aktivnosti i nije istovremeno zahvatila cijeli svijet. Korona-kriza i lockdown koji smo imali tijekom proljeća 2020. godine osvijestili su sve slabosti hrvatske poljoprivrede i proizvodnje hrane. Kriza je otvorila pitanje niske razine samodostatnosti u gotovo svim proizvodnjama. U Hrvatskoj je smanjenje potrošnje i aktivnosti poduzeća dovelo do snažnog pada BDP-a zbog čega je Vlada od početka epidemije poduzela čitav niz mjera radi očuvanja radnih mjesta, likvidnosti poduzeća i makroekonomske stabilnosti. Vlada Republike Hrvatske je pripremila Nacionalni plan oporavka i otpornosti za period 2021. – 2026. čiji je cilj oporaviti sve one djelatnosti pogođene ovom krizom. Oporaviti, unaprijediti, ali i ukloniti sve one nedostatke koji su mučili dosadašnjih godina našu poljoprivredu, zdravstvo, obrazovni sustav i sl. Cilj istraživanja u radu je sa teorijskog aspekta prikazati ulogu i značaj pandemija u društvu te identificirati posljedice koje pojave bolesti mogu izazvati kroz povijest, sadašnjost i budućnost reflektirajući se na gospodarstvo. Prilikom istraživanja pažnja je bila usmjerena na korištenje najnovijih dostupnih podataka kako bi se što vjerodostojnije i kvalitetnije obradila tema diplomskog rada. Primjenjena je metoda sinteze i deskripcije prilikom interpretacije dobivenih rezultata kao i formiranja zaključaka.Diseases that occur greatly affect human life, but not only him but also the overall functioning of the state in which he lives. The economic crisis caused by the Covid-19 corona virus is unique in economic history so far in terms of the manner and speed of its occurrence, global coverage and consequences. No economic crisis so far has occurred so quickly with a deep decline in economic activity and has not affected the whole world at the same time. The corona crisis and lockdown we had during the spring of 2020 made us aware of all the weaknesses of Croatian agriculture and food production. The crisis has raised the issue of low levels of selfsufficiency in almost all industries. In Croatia, the reduction in consumption and corporate activity has led to a sharp drop in GDP, which is why the Government has taken a number of measures since the beginning of the epidemic to preserve jobs, corporate liquidity and macroeconomic stability. The Government of the Republic of Croatia has prepared a National Recovery and Resilience Plan for the period 2021-2026, the aim of which is to recover all those activities affected by this crisis. Recover, improve, but also remove all the shortcomings that have plagued our agriculture, health, education system, etc. The aim of the research is to present the role and significance of pandemics in society from a theoretical point of view and to identify the consequences that disease occurrences can cause through history, present and future, reflecting on the economy. During the research, attention was focused on the use of the latest available data in order to process the topic of the thesis as credibly and qualitatively as possible. The method of synthesis and description was applied during the interpretation of the obtained results as well as the formation of conclusions

Development of innovative products as a tool to revitalize the sheep breeding sector

Ovčarstvo je grana stočarstva koja u Republici Hrvatskoj postupno povećava svoj opseg i sa sobom donosi značajne i vrijedne nusproizvode koji su dakako iskoristivi, a jedan od takvih je i ovčja vuna. Naslov “Razvoj inovativnih proizvoda kao instrument revitalizacije ovčarstva” jasno ukazuje na činjenicu kako mjesta za inovativnost u poljoprivredi svakako ima. Srž rada je poslovni plan otkupa i prerade ovčje vune u toplinsku izolaciju kojim se rješava značajan ekološki problem, a s druge strane stimulira poljoprivredna proizvodnja. Vuna je sirovina koja se odlikuje brojnim pozitivnim svojstvima te širokom paletom proizvoda koji se od nje mogu dobiti.Prikazan je potpuno razvijeni poslovni plan u kojem se jasno definira misija i vizija poslovanja, detaljan opis tehnološkog procesa te marketinški i financijski plan. Neizostavan je dio i SWOT analiza gdje su prikazane snage i slabosti poduzetničkog projekta. Prikazane su projekcije za prvih pet godina poslovanja uključujući i analizu osjetljivosti koje potvrđuju kako je projekt isplativ.Sheep farming is a branch of cattle breeding which gradually increases its size in the Republic of Croatia and brings with it significant and valuable by-products that are of course utilized, and one of these is sheep's wool. The title "Development of innovative products as a tool to revitalize the sheep breeding sector" clearly points to the fact that the places for innovation in agriculture certainly have. The core of business is the business plan for the purchase and processing of sheep wool in thermal insulation, which solves a significant environmental problem, while on the other hand stimulates agricultural production. Wool is a raw material that has many positive properties and a wide range of products that can be obtained from it.A fully developed business plan clearly defines the mission and vision of the business, a detailed description of the technological process and the marketing and financial plan. It is an indispensable part of SWOT analysis where the strengths and weaknesses of the entrepreneurial project are presented. Projections for the first five years of operations are included, including sensitivity analysis that confirms the project is profitable

Revitalization of the Croatian economy caused by the COVID-19 pandemic with an emphasis on the agricultural sector

Bolesti koje se pojave utječu uvelike na ljudski život, ali ne samo na njega već i na cjelokupno funkcioniranje države u kojoj on biva. Gospodarska kriza izazvana korona virusom Covid-19 jedinstvena je u dosadašnjoj ekonomskoj povijesti po načinu i brzini nastanka, globalnom obuhvatu i posljedicama. Nijedna dosadašnja ekonomska kriza nije nastupila tako brzo s dubokim padom gospodarskih aktivnosti i nije istovremeno zahvatila cijeli svijet. Korona-kriza i lockdown koji smo imali tijekom proljeća 2020. godine osvijestili su sve slabosti hrvatske poljoprivrede i proizvodnje hrane. Kriza je otvorila pitanje niske razine samodostatnosti u gotovo svim proizvodnjama. U Hrvatskoj je smanjenje potrošnje i aktivnosti poduzeća dovelo do snažnog pada BDP-a zbog čega je Vlada od početka epidemije poduzela čitav niz mjera radi očuvanja radnih mjesta, likvidnosti poduzeća i makroekonomske stabilnosti. Vlada Republike Hrvatske je pripremila Nacionalni plan oporavka i otpornosti za period 2021. – 2026. čiji je cilj oporaviti sve one djelatnosti pogođene ovom krizom. Oporaviti, unaprijediti, ali i ukloniti sve one nedostatke koji su mučili dosadašnjih godina našu poljoprivredu, zdravstvo, obrazovni sustav i sl. Cilj istraživanja u radu je sa teorijskog aspekta prikazati ulogu i značaj pandemija u društvu te identificirati posljedice koje pojave bolesti mogu izazvati kroz povijest, sadašnjost i budućnost reflektirajući se na gospodarstvo. Prilikom istraživanja pažnja je bila usmjerena na korištenje najnovijih dostupnih podataka kako bi se što vjerodostojnije i kvalitetnije obradila tema diplomskog rada. Primjenjena je metoda sinteze i deskripcije prilikom interpretacije dobivenih rezultata kao i formiranja zaključaka.Diseases that occur greatly affect human life, but not only him but also the overall functioning of the state in which he lives. The economic crisis caused by the Covid-19 corona virus is unique in economic history so far in terms of the manner and speed of its occurrence, global coverage and consequences. No economic crisis so far has occurred so quickly with a deep decline in economic activity and has not affected the whole world at the same time. The corona crisis and lockdown we had during the spring of 2020 made us aware of all the weaknesses of Croatian agriculture and food production. The crisis has raised the issue of low levels of selfsufficiency in almost all industries. In Croatia, the reduction in consumption and corporate activity has led to a sharp drop in GDP, which is why the Government has taken a number of measures since the beginning of the epidemic to preserve jobs, corporate liquidity and macroeconomic stability. The Government of the Republic of Croatia has prepared a National Recovery and Resilience Plan for the period 2021-2026, the aim of which is to recover all those activities affected by this crisis. Recover, improve, but also remove all the shortcomings that have plagued our agriculture, health, education system, etc. The aim of the research is to present the role and significance of pandemics in society from a theoretical point of view and to identify the consequences that disease occurrences can cause through history, present and future, reflecting on the economy. During the research, attention was focused on the use of the latest available data in order to process the topic of the thesis as credibly and qualitatively as possible. The method of synthesis and description was applied during the interpretation of the obtained results as well as the formation of conclusions

Revitalization of the Croatian economy caused by the COVID-19 pandemic with an emphasis on the agricultural sector

Bolesti koje se pojave utječu uvelike na ljudski život, ali ne samo na njega već i na cjelokupno funkcioniranje države u kojoj on biva. Gospodarska kriza izazvana korona virusom Covid-19 jedinstvena je u dosadašnjoj ekonomskoj povijesti po načinu i brzini nastanka, globalnom obuhvatu i posljedicama. Nijedna dosadašnja ekonomska kriza nije nastupila tako brzo s dubokim padom gospodarskih aktivnosti i nije istovremeno zahvatila cijeli svijet. Korona-kriza i lockdown koji smo imali tijekom proljeća 2020. godine osvijestili su sve slabosti hrvatske poljoprivrede i proizvodnje hrane. Kriza je otvorila pitanje niske razine samodostatnosti u gotovo svim proizvodnjama. U Hrvatskoj je smanjenje potrošnje i aktivnosti poduzeća dovelo do snažnog pada BDP-a zbog čega je Vlada od početka epidemije poduzela čitav niz mjera radi očuvanja radnih mjesta, likvidnosti poduzeća i makroekonomske stabilnosti. Vlada Republike Hrvatske je pripremila Nacionalni plan oporavka i otpornosti za period 2021. – 2026. čiji je cilj oporaviti sve one djelatnosti pogođene ovom krizom. Oporaviti, unaprijediti, ali i ukloniti sve one nedostatke koji su mučili dosadašnjih godina našu poljoprivredu, zdravstvo, obrazovni sustav i sl. Cilj istraživanja u radu je sa teorijskog aspekta prikazati ulogu i značaj pandemija u društvu te identificirati posljedice koje pojave bolesti mogu izazvati kroz povijest, sadašnjost i budućnost reflektirajući se na gospodarstvo. Prilikom istraživanja pažnja je bila usmjerena na korištenje najnovijih dostupnih podataka kako bi se što vjerodostojnije i kvalitetnije obradila tema diplomskog rada. Primjenjena je metoda sinteze i deskripcije prilikom interpretacije dobivenih rezultata kao i formiranja zaključaka.Diseases that occur greatly affect human life, but not only him but also the overall functioning of the state in which he lives. The economic crisis caused by the Covid-19 corona virus is unique in economic history so far in terms of the manner and speed of its occurrence, global coverage and consequences. No economic crisis so far has occurred so quickly with a deep decline in economic activity and has not affected the whole world at the same time. The corona crisis and lockdown we had during the spring of 2020 made us aware of all the weaknesses of Croatian agriculture and food production. The crisis has raised the issue of low levels of selfsufficiency in almost all industries. In Croatia, the reduction in consumption and corporate activity has led to a sharp drop in GDP, which is why the Government has taken a number of measures since the beginning of the epidemic to preserve jobs, corporate liquidity and macroeconomic stability. The Government of the Republic of Croatia has prepared a National Recovery and Resilience Plan for the period 2021-2026, the aim of which is to recover all those activities affected by this crisis. Recover, improve, but also remove all the shortcomings that have plagued our agriculture, health, education system, etc. The aim of the research is to present the role and significance of pandemics in society from a theoretical point of view and to identify the consequences that disease occurrences can cause through history, present and future, reflecting on the economy. During the research, attention was focused on the use of the latest available data in order to process the topic of the thesis as credibly and qualitatively as possible. The method of synthesis and description was applied during the interpretation of the obtained results as well as the formation of conclusions

Development of innovative products as a tool to revitalize the sheep breeding sector

Ovčarstvo je grana stočarstva koja u Republici Hrvatskoj postupno povećava svoj opseg i sa sobom donosi značajne i vrijedne nusproizvode koji su dakako iskoristivi, a jedan od takvih je i ovčja vuna. Naslov “Razvoj inovativnih proizvoda kao instrument revitalizacije ovčarstva” jasno ukazuje na činjenicu kako mjesta za inovativnost u poljoprivredi svakako ima. Srž rada je poslovni plan otkupa i prerade ovčje vune u toplinsku izolaciju kojim se rješava značajan ekološki problem, a s druge strane stimulira poljoprivredna proizvodnja. Vuna je sirovina koja se odlikuje brojnim pozitivnim svojstvima te širokom paletom proizvoda koji se od nje mogu dobiti.Prikazan je potpuno razvijeni poslovni plan u kojem se jasno definira misija i vizija poslovanja, detaljan opis tehnološkog procesa te marketinški i financijski plan. Neizostavan je dio i SWOT analiza gdje su prikazane snage i slabosti poduzetničkog projekta. Prikazane su projekcije za prvih pet godina poslovanja uključujući i analizu osjetljivosti koje potvrđuju kako je projekt isplativ.Sheep farming is a branch of cattle breeding which gradually increases its size in the Republic of Croatia and brings with it significant and valuable by-products that are of course utilized, and one of these is sheep's wool. The title "Development of innovative products as a tool to revitalize the sheep breeding sector" clearly points to the fact that the places for innovation in agriculture certainly have. The core of business is the business plan for the purchase and processing of sheep wool in thermal insulation, which solves a significant environmental problem, while on the other hand stimulates agricultural production. Wool is a raw material that has many positive properties and a wide range of products that can be obtained from it.A fully developed business plan clearly defines the mission and vision of the business, a detailed description of the technological process and the marketing and financial plan. It is an indispensable part of SWOT analysis where the strengths and weaknesses of the entrepreneurial project are presented. Projections for the first five years of operations are included, including sensitivity analysis that confirms the project is profitable

Development of innovative products as a tool to revitalize the sheep breeding sector

Ovčarstvo je grana stočarstva koja u Republici Hrvatskoj postupno povećava svoj opseg i sa sobom donosi značajne i vrijedne nusproizvode koji su dakako iskoristivi, a jedan od takvih je i ovčja vuna. Naslov “Razvoj inovativnih proizvoda kao instrument revitalizacije ovčarstva” jasno ukazuje na činjenicu kako mjesta za inovativnost u poljoprivredi svakako ima. Srž rada je poslovni plan otkupa i prerade ovčje vune u toplinsku izolaciju kojim se rješava značajan ekološki problem, a s druge strane stimulira poljoprivredna proizvodnja. Vuna je sirovina koja se odlikuje brojnim pozitivnim svojstvima te širokom paletom proizvoda koji se od nje mogu dobiti.Prikazan je potpuno razvijeni poslovni plan u kojem se jasno definira misija i vizija poslovanja, detaljan opis tehnološkog procesa te marketinški i financijski plan. Neizostavan je dio i SWOT analiza gdje su prikazane snage i slabosti poduzetničkog projekta. Prikazane su projekcije za prvih pet godina poslovanja uključujući i analizu osjetljivosti koje potvrđuju kako je projekt isplativ.Sheep farming is a branch of cattle breeding which gradually increases its size in the Republic of Croatia and brings with it significant and valuable by-products that are of course utilized, and one of these is sheep's wool. The title "Development of innovative products as a tool to revitalize the sheep breeding sector" clearly points to the fact that the places for innovation in agriculture certainly have. The core of business is the business plan for the purchase and processing of sheep wool in thermal insulation, which solves a significant environmental problem, while on the other hand stimulates agricultural production. Wool is a raw material that has many positive properties and a wide range of products that can be obtained from it.A fully developed business plan clearly defines the mission and vision of the business, a detailed description of the technological process and the marketing and financial plan. It is an indispensable part of SWOT analysis where the strengths and weaknesses of the entrepreneurial project are presented. Projections for the first five years of operations are included, including sensitivity analysis that confirms the project is profitable