Convergence of adaptive mixtures of importance sampling schemes

In the design of efficient simulation algorithms, one is often beset with a poor choice of proposal distributions. Although the performance of a given simulation kernel can clarify a posteriori how adequate this kernel is for the problem at hand, a permanent on-line modification of kernels causes concerns about the validity of the resulting algorithm. While the issue is most often intractable for MCMC algorithms, the equivalent version for importance sampling algorithms can be validated quite precisely. We derive sufficient convergence conditions for adaptive mixtures of population Monte Carlo algorithms and show that Rao--Blackwellized versions asymptotically achieve an optimum in terms of a Kullback divergence criterion, while more rudimentary versions do not benefit from repeated updating.Comment: Published at http://dx.doi.org/10.1214/009053606000001154 in the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org

A low-luminosity type-1 QSO sample; III. Optical spectroscopic properties and activity classification

We report on the optical spectroscopic analysis of a sample of 99 low-luminosity quasi-stellar objects (LLQSOs) at $z\leq 0.06$ base the Hamburg/ESO QSO survey (HES). The LLQSOs presented here offer the possibility of studying the faint end of the QSO population at smaller cosmological distances and, therefore, in greater detail. A small number of our LLQSO present no broad component. Two sources show double broad components, whereas six comply with the classic NLS1 requirements. As expected in NLR of broad line AGNs, the [S{\sc{ii}}]$-$based electron density values range between 100 and 1000 N$_{e}$/cm$^{3}$. Using the optical characteristics of Populations A and B, we find that 50\% of our sources with H$\beta$ broad emission are consistent with the radio-quiet sources definition. The remaining sources could be interpreted as low-luminosity radio-loud quasar. The BPT-based classification renders an AGN/Seyfert activity between 50 to 60\%. For the remaining sources, the possible star burst contribution might control the LINER and HII classification. Finally, we discuss the aperture effect as responsible for the differences found between data sets, although variability in the BLR could play a significant role as well.Comment: 22 pages; 5 tables; 17 figures; in press with A&

Entropy of vortex cores on the border of the superconductor-to-insulator transition in an underdoped cuprate

We present a study of Nernst effect in underdoped $La_{2-x}Sr_xCuO_4$ in magnetic fields as high as 28T. At high fields, a sizeable Nernst signal was found to persist in presence of a field-induced non-metallic resistivity. By simultaneously measuring resistivity and the Nernst coefficient, we extract the entropy of vortex cores in the vicinity of this field-induced superconductor-insulator transition. Moreover, the temperature dependence of the thermo-electric Hall angle provides strong constraints on the possible origins of the finite Nernst signal above $T_c$, as recently discovered by Xu et al.Comment: 5 Pages inculding 4 figure

Exploiting the layer-by-layer nanoarchitectonics for the fabrication of polymer capsules : A toolbox to provide multifunctional properties to target complex pathologies

Polymer capsules fabricated via the layer-by-layer (LbL) approach have attracted a great deal of attention for biomedical applications thanks to their tunable architecture. Compared to alternative methods, in which the precise control over the final properties of the systems is usually limited, the intrinsic versatility of the LbL approach allows the functionalization of all the constituents of the polymeric capsules following relatively simple protocols. In fact, the final properties of the capsules can be adjusted from the inner cavity to the outer layer through the polymeric shell, resulting in therapeutic, diagnostic, or theranostic (i.e., combination of therapeutic and diagnostic) agents that can be adapted to the particular characteristics of the patient and face the challenges encountered in complex pathologies. The biomedical industry demands novel biomaterials capable of targeting several mechanisms and/or cellular pathways simultaneously while being tracked by minimally invasive tech-niques, thus highlighting the need to shift from monofunctional to multifunctional polymer capsules. In the present review, those strategies that permit the advanced functionalization of polymer capsules are accordingly introduced. Each of the constituents of the capsule (i.e., cavity, multilayer membrane and outer layer) is thor-oughly analyzed and a final overview of the combination of all the strategies toward the fabrication of multi-functional capsules is presented. Special emphasis is given to the potential biomedical applications of these multifunctional capsules, including particular examples of the performed in vitro and in vivo validation studies. Finally, the challenges in the fabrication process and the future perspective for their safe translation into the clinic are summarized.Peer reviewe

Corrigendum: Initiating Change of People With Criminal Justice Involvement Through Participation in a Drama Project: An Exploratory Study

Author proofs are not yet ready for revisio

Parallel transport modeling of linear divertor simulators with fundamental ion cyclotron heating

The Material Plasma Exposure eXperiment (MPEX) is a steady state linear device with the goal to perform plasma material interaction (PMI) studies at future fusion reactor relevant conditions. A prototype of MPEX referred as Porto-MPEX is designed to carry out research and development related to source, heating and transport concepts on the planned full MPEX device. The auxiliary heating schemes in MPEX are based on cyclotron resonance heating with radio frequency (RF) waves. Ion cyclotron heating (ICH) and electron cyclotron heating (ECH) in MPEX are used to independently heat the ions and electrons and provide fusion divertor conditions ranging from sheath-limited to fully detached divertor regimes at a material target. A Hybrid Particle-In-Cell code- PICOS++ is developed and applied to understand the plasma parallel transport during ICH heating in MPEX Proto-MPEX to the target. With this tool, evolution of the distribution function of MPEX/Proto-MPEX ions is modeled in the presence of (1) Coulomb collisions, (2) volumetric particle sources and (3) quasi-linear RF-based ICH. The code is benchmarked against experimental data from Proto-MPEX and simulation data from B2.5 EIRENE. The experimental observation of density-drop near the target in Proto-MPEX and MPEX during ICH heating is demonstrated and explained via physics-based arguments using PICOS++ modeling. In fact, the density drops at the target during ICH in Proto-MPEX/MPEX to conserve the flux and to compensate for the increased flow during ICH. Furthermore, sensitivity scans of various plasma parameters with respect to ICH power are performed for MPEX to investigate its role on plasma transport and particle and energy fluxes at the target. Finally, we discuss the pathway to model ECH in MPEX using the Hybrid PIC formulation herein presented for kinetic electrons and fluid ions