Cancer Burden and Control in the Western Pacific Region: Challenges and Opportunities

Background: Cancer has become a priority public health challenge in the Member States of the World Health Organization’s (WHO) Western Pacific Region (WPR). Rapid and unplanned urbanization, demographic transition, and lifestyle changes are driving the increase in noncommunicable diseases (NCDs), which include cancer. The WHO Global Action Plan for the Prevention and Control of Noncommunicable Diseases 2013-2020, targets a reduction in premature mortality from NCDs by 25% by 2025. Objectives: The aim of this study was to review the epidemiology of cancer including cancer controlefforts in the WPR. Methods: Information was primarily extracted from Globocan 2012, 'Cancer Incidence in Five Continents Vol. X', and the NCD country capacity survey carried out by the WHO in 2013. The WPR, with one-fourth of the world’s population, has one-third of all cancers globally. Cancer cases in the WPR are expected to increase from 4.5 million new cases in 2012 to 6.4 million in 2025. Findings: In most of the low- and middle-income countries (LMICs) in Asia and in Pacific Island countries and areas, coverage of cancer registration is relatively low and they face many challenges in quality of cancer registry data. Eighty-five percent of LMICs have indicated the existence of a cancer control policy strategy and/or action plan. The predominance of lung, stomach, colorectal, breast, and cervical cancers makes control of the disease more amenable in the WPR. A relatively high ratio of mortality to incidence in LMICs reflects health-system limitations, especially in the diagnosis and management of cancer. Conclusions: Strengthening cancer registration, tobacco control, and promotion of a healthy diet, as well as HBV and HPV vaccination, is the priority areas to reduce cancer burden. Health-system strengthening with a defined package of services at different levels, referral care, trained human resources, and appropriate technology is necessary to improve cancer management. Pain relief and palliative care are priorities as well. A well-planned national cancer control program with a strong component of surveillance and monitoring can help to reduce the cancer burden in LMICs and Pacific Island countries

Deep Exploration of ϵ Eridani with Keck Ms-band Vortex Coronagraphy and Radial Velocities: Mass and Orbital Parameters of the Giant Exoplanet

We present the most sensitive direct imaging and radial velocity (RV) exploration of epsilon Eridani to date. epsilon Eridani is an adolescent planetary system, reminiscent of the early solar system. It is surrounded by a prominent and complex debris disk that is likely stirred by one or several gas giant exoplanets. The discovery of the RV signature of a giant exoplanet was announced 15 yr ago, but has met with scrutiny due to possible confusion with stellar noise. We confirm the planet with a new compilation and analysis of precise RV data spanning 30 yr, and combine it with upper limits from our direct imaging search, the most sensitive ever performed. The deep images were taken in the Ms band (4.7 μm) with the vortex coronagraph recently installed in W.M. Keck Observatory's infrared camera NIRC2, which opens a sensitive window for planet searches around nearby adolescent systems. The RV data and direct imaging upper limit maps were combined in an innovative joint Bayesian analysis, providing new constraints on the mass and orbital parameters of the elusive planet. epsilon Eridani b has a mass of 0.78_(-0.12)^(+0.38} M_(Jup) and is orbiting epsilon Eridani at about 3.48 ± 0.02 au with a period of 7.37 ± 0.07 yr. The eccentricity of epsilon Eridani b's orbit is 0.07_(-0.05)^(+0.06), an order of magnitude smaller than early estimates and consistent with a circular orbit. We discuss our findings from the standpoint of planet–disk interactions and prospects for future detection and characterization with the James Webb Space Telescope

Density of outdoor food and beverage advertising around schools in Ulaanbaatar (Mongolia) and Manila (The Philippines) and implications for policy

Children’s exposure to unhealthy food marketing is recognised by leading international health organisations as a probable causal factor for obesity. Outdoor advertising near schools embeds commercial food messages into children’s everyday lives and acts as a cue for food purchases. This project aimed to describe food advertising in the area around schools in two demographically and culturally disparate cities in the Asia Pacific Region. Data on outdoor food advertising were collected from the area within 500 m of 30 primary schools in each of two cities: Ulaanbaatar, Mongolia and Manila, The Philippines. For each food advertisement, information was collected on: distance from the school (within 250 or 500 m); size, setting, type and position of the advertisement; and the food/drink product type promoted (core/healthy, non-core/unhealthy and miscellaneous). Density of advertisements was calculated per 100 m2. The density of food advertising was twice as high in the area closest to schools compared to the area further from schools (.9 vs. .5 in Ulaanbaatar and 6.5 vs. 3.3 advertisements per 100 m2 in Manila). Almost all food advertisements were for non-core/unhealthy foods/drinks (92% in Ulaanbaatar and 85% in Manila), and soft drinks were most frequently promoted. Children in Ulaanbaatar and Manila are exposed to large numbers of advertisements for unhealthy foods/drinks on their way to and from school, and these are particularly clustered within the immediate vicinity of schools. Clear directions for policy development are outlined to reduce children’s exposure to this marketing, including restricting the placement and content of outdoor advertising

Deep Exploration of epsilon Eridani with Keck Ms-band Vortex Coronagraphy and Radial Velocities: Mass and Orbital Parameters of the Giant Exoplanet

© 2019. The American Astronomical Society. All rights reserved. We present the most sensitive direct imaging and radial velocity (RV) exploration of Eridani to date. Eridani is an adolescent planetary system, reminiscent of the early solar system. It is surrounded by a prominent and complex debris disk that is likely stirred by one or several gas giant exoplanets. The discovery of the RV signature of a giant exoplanet was announced 15 yr ago, but has met with scrutiny due to possible confusion with stellar noise. We confirm the planet with a new compilation and analysis of precise RV data spanning 30 yr, and combine it with upper limits from our direct imaging search, the most sensitive ever performed. The deep images were taken in the Ms band (4.7 μm) with the vortex coronagraph recently installed in W.M. Keck Observatory's infrared camera NIRC2, which opens a sensitive window for planet searches around nearby adolescent systems. The RV data and direct imaging upper limit maps were combined in an innovative joint Bayesian analysis, providing new constraints on the mass and orbital parameters of the elusive planet. Eridani b has a mass of M Jup and is orbiting Eridani at about 3.48 ± 0.02 au with a period of 7.37 ± 0.07 yr. The eccentricity of Eridani b's orbit is an order of magnitude smaller than early estimates and consistent with a circular orbit. We discuss our findings from the standpoint of planet-disk interactions and prospects for future detection and characterization with the James Webb Space Telescope.status: publishe

DEEP EXPLORATION OF ERIDANI WITH KECK MS-BAND VORTEX CORONAGRAPHY AND RADIAL VELOCITIES: MASS AND ORBITAL PARAMETERS OF THE GIANT EXOPLANET

International audienc

Keck/NIRC2 L’-band Imaging of Jovian-mass Accreting Protoplanets around PDS 70

We present L'-band imaging of the PDS 70 planetary system with Keck/NIRC2 using the new infrared pyramid wave front sensor. We detected both PDS 70 b and c in our images, as well as the front rim of the circumstellar disk. After subtracting off a model of the disk, we measured the astrometry and photometry of both planets. Placing priors based on the dynamics of the system, we estimated PDS 70 b to have a semimajor axis of 20(-4)(+3) au and PDS 70 c to have a semimajor axis of 34(-6)(+12) au (95% credible interval). We fit the spectral energy distribution (SED) of both planets. For PDS 70 b, we were able to place better constraints on the red half of its SED than previous studies and inferred the radius of the photosphere to be 2-3 R-Jup. The SED of PDS 70 c is less well constrained, with a range of total luminosities spanning an order of magnitude. With our inferred radii and luminosities, we used evolutionary models of accreting protoplanets to derive a mass of PDS 70 b between 2 and 4 M-Jup and a mean mass accretion rate between 3 x 10(-7) and 8 x 10(-7) M-Jup/yr. For PDS 70 c, we computed a mass between 1 and 3 M-Jup and mean mass accretion rate between 1 x 10(-7) and 5 x 10(-7) M-Jup/yr. The mass accretion rates imply dust accretion timescales short enough to hide strong molecular absorption features in both planets' SEDs.National Science FoundationThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]