GAMBARAN PENGETAHUAN TENTANG POLA MAKAN PADA PASIEN GASTRITIS DI POLI UMUM RUMAH SAKIT ISLAM SURABAYA

Gastritis merupakan penyakit radang mukosa lambung yang tiap tahun mengalami peningkatan. Tingkat pengetahuan yang kurang tentang pola makan adalah salah satu penyebab terjadinya kekambuhan. Penelitian ini bertujuan untuk mengetahui gambaran pengetahuan tentang pola makan pada pasien gastritis di Poli Umum Rumah Sakit Islam Surabaya. Desain penelitian ini adalah deskriptif, populasi adalah semua pasien Poli Umum yang didiagnosis gastritis sebesar 60 orang dan besar sampel 52 responden.Teknik pengambilan sampel Probabilitiy samples jenis simple random sampling. Variabel penelitian, Pengetahuan Pola Makan Pada Pasien Gastritis, Instrumen penelitian menggunakan kuesioner dan data dianalisis secara deskriptif, dengan persentase. Hasil penelitian didapatkan sebagian besar 27 responden (52%) memilki pengetahuan kurang, 15 (28,8%) pengetahuan cukup dan 10 (19,2%) memiliki pengetahuan baik. Simpulan dari penelitian ini adalah pasien yang berobat di Poli Umum RSI Surabaya sebagian besar mempunyai pengetahuan kurang tentang pola makan pada pasien gastritis. Diharapkan bagi pasien gastritis dapat berpartisipasi secara aktif untuk terus mencari informasi dalam rangka menambah pengetahuan tentang pola makan yang baik dan aman untuk pasien gastritis

Membangun Budaya Literasi Bagi Anak Didik Di Taman Bacaan Masyarakat (TBM) Al-Azahri Martubung Medan Labuhan

Kegiatan pengabdian masyarakat ini dilaksanakan di Taman Bacaan Masyarakat Al-Azahari Martubung, Kecamatan Medan Labuhan. Kegiatan yang dilaksanakan berupa pemaparan pemahaman tentang bagaimana membangun budaya literasi anak didik dengan pengelola Taman Bacaan Masyarakat (TBM) Al-Azhari Martubung. Pemaparan materi dan pelatihan kepada anak didik yang dilakukan berupa ceramah, pemaparan dan penyampaian secara langsung yang dibantu oleh alat atau bahan pendukung adalah laptop yang terhubung dengan koneksi internet dan menggunakan in-fokus. Adapun Metode Penelitian ini adalah menggunakan Pendekatan Pelatihan. Masalah yang sering terjadi adalah ketidakpahaman anak didik tentang budaya literasi di Taman Bacaan Masyarakat  tersebut. Cakupannya adalah dalam mengenali anak cara membaca yang baik, menulis, berhitung, mengenali sosial serta hal-hal yang membuat anak didik berkembang dan berinovasi. Untuk itu dalam pelatihan ini diharapkan kepada anak didik maupun pengelola Taman Bacaan Masyrakat (TBM) mampu memahami budaya literasi dengan baik. Karena peranan taman bacaan masyarakat sangat penting dalam membina dan membangun budaya literasi anak didik dengan baik serta meningkatkan minat baca yang menjadi pembina, fasilitator, pendidik dan wadah pembangunan sumber daya manusia. Selanjutnya pendukung kegiatan ini juga tak lepas dari koleksi bahan bacaan yang tersedia di TBM serta media informasi lainnya yang dapat mendukung aktivitas pembelajaran anak didik

Tinjauan Psiko-Teologi Terhadap Fenomena Kekerasan Dalam Pacaran Pada Remaja

Fenomena kekerasan dalam berpacaran bukan hanya terjadi di ruang tertutup atau pribadi saja melainkan sangat mudah ditemukan di ruang publik seperti halaman sekolah, tempat rental komputer, taman, trotoar, kendaraan umum, pada penumpang kendaraan roda dua di tengah lalu lintas. Dan ketika peristiwa itu berlangsung serta disaksikan oleh masyarakat umum, pelaku dan korban tidak merasa terganggu, rikuh, malu, atau berhenti. Padahal kekerasan dalam pacaran di kalangan remaja merupakan salah satu akses kepada kekerasan dalam rumah tangga, apabila hal ini tidak ditangani secara benar sebelum berkelanjutan dengan korban yang mengalami dampak pada fisik, psikis, sosial, moral, ekonomi dan masa depan generasi penerus. Metode yang digunakan adalah penelitian deskriptif dengan mengkaji fenomena kekerasan dalam pacaran dari sudut pandang Alkitab dan psikologi, dimana secara psikologis kekerasan seksual yang terjadi pada masa remaja berdampak negatif bagi pelaku maupun korban kekerasan seksual. Adapun kekerasan pada masa berpacaran dapat disebabkan karena remaja mengalami loncatan akibat gejolak hormon dan pesatnya teknologi informasi. Secara teologis hubungan seks sebelum menikah adalah tindakan merusak kehidupan para pelakunya dan kekerasan pada masa berpacaran merupakan tindakan yang bertentangan dengan konsep imago dei.  The phenomenon of dating violence does not only occur in closed or private spaces but is very easy to find in public spaces such as school yards, computer rental places, parks, sidewalks, public transportation, on two-wheeled vehicle passengers in the middle of traffic. And when the event took place and was witnessed by the general public, the perpetrators and victims did not feel disturbed, uncomfortable, embarrassed, or stopped. Whereas violence in courtship among adolescents is one access to domestic violence, if this is not handled properly before it is sustained with victims who have an impact on the physical, psychological, social, moral, economic and future generations. The method used is descriptive research by examining the phenomenon of dating violence from the perspective of the Bible and psychology, where psychologically sexual violence that occurs during adolescence has a negative impact on perpetrators and victims of sexual violence. The violence during dating can be caused by adolescents experiencing jumps due to hormone fluctuations and rapid information technology. Theologically sex before marriage is an act of destroying the lives of the perpetrators and violence during dating is an action that is contrary to the concept of Imago dei.

PENGARUH PENGAWASAN, LINGKUNGAN KERJA DAN FASILITAS KERJA TERHADAP PRESTASI KERJA PEGAWAI DINAS PERPUSTAKAAN DAN KEARSIPAN KOTA TANJUNGBALAI

The formulation of the problem in this study is whether the supervision, work environment and facilities simultaneously have a positive and significant effect on the work performance at Library and Records Office, Kota Tanjungbalai. This study aims to determine the effect of supervision, work environment and facilities on the work performance of the employees at Library and Records Office, Kota Tanjungbalai. The sample in this study were all employees at Library and Records Office, Kota Tanjungbalai, which numbered 38 people. The data analysis technique in this research is Multiple Linear Regression. The results of this study indicate; Partial supervision has a positive and significant effect on employee work performance; The work environment partially has a positive and significant effect on employee work performance; Work facilities partially have a positive and significant effect on employee work performance; Supervision, work environment and work facilities simultaneously have a positive and significant effect on employee performance. Keywords : Supervision; Work environment; Work Facilities; Work performanc

Chromatin Profiles of Chromosomally Integrated Human Herpesvirus-6A

Human herpesvirus-6A (HHV-6A) and 6B (HHV-6B) are two closely related betaherpesviruses that are associated with various diseases including seizures and encephalitis. The HHV-6A/B genomes have been shown to be present in an integrated state in the telomeres of latently infected cells. In addition, integration of HHV-6A/B in germ cells has resulted in individuals harboring this inherited chromosomally integrated HHV-6A/B (iciHHV-6) in every cell of their body. Until now, the viral transcriptome and the epigenetic modifications that contribute to the silencing of the integrated virus genome remain elusive. In the current study, we used a patient-derived iciHHV-6A cell line to assess the global viral gene expression profile by RNA-seq, and the chromatin profiles by MNase-seq and ChIP-seq analyses. In addition, we investigated an in vitro generated cell line (293-HHV-6A) that expresses GFP upon the addition of agents commonly used to induce herpesvirus reactivation such as TPA. No viral gene expression including miRNAs was detected from the HHV-6A genomes, indicating that the integrated virus is transcriptionally silent. Intriguingly, upon stimulation of the 293-HHV-6A cell line with TPA, only foreign promoters in the virus genome were activated, while all HHV-6A promoters remained completely silenced. The transcriptional silencing of latent HHV-6A was further supported by MNase-seq results, which demonstrate that the latent viral genome resides in a highly condensed nucleosome-associated state. We further explored the enrichment profiles of histone modifications via ChIP-seq analysis. Our results indicated that the HHV-6 genome is modestly enriched with the repressive histone marks H3K9me3/H3K27me3 and does not possess the active histone modifications H3K27ac/H3K4me3. Overall, these results indicate that HHV-6 genomes reside in a condensed chromatin state, providing insight into the epigenetic mechanisms associated with the silencing of the integrated HHV-6A genome

Development and stability evaluation of olive oil nanoemulsion using sucrose ester

Nanoemulsion is a type of emulsion that consist of fine oil-in-water dispersions, with the droplets covering the size range of 20-200nm. It can be achieved through self-emulsification process. One of the processes is through low energy emulsification method. Olive oil was chosen in this study due to its efficiency in treating skin problem. Pre-emulsion was prepared by mixing oil, sucrose ester and glycerol under heat at 80 °C. After the pre-emulsion was formed, it will be self-emulsified with water under gentle agitation. Olive oil nanoemulsion was prepared using sucrose ester as a surfactant to produce droplets size below 200 nm with low size distribution. The pre-emulsion was very stable when stored at 4 “C. However, it was unstable when stored at 25 °C and 40 °C. Therefore, 4 °C is the ideal storage condition for this pre-emulsion

Higher-Order Chromatin Structures of Chromosomally Integrated HHV-6A Predict Integration Sites

Human herpesvirus -6A and 6B (HHV-6A/B) can integrate their genomes into the telomeres of human chromosomes. Viral integration can occur in several cell types, including germinal cells, resulting in individuals that harbor the viral genome in every cell of their body. The integrated genome is efficiently silenced but can sporadically reactivate resulting in various clinical symptoms. To date, the integration mechanism and the subsequent silencing of HHV-6A/B genes remains poorly understood. Here we investigate the genome-wide chromatin contacts of the integrated HHV-6A in latently-infected cells. We show that HHV-6A becomes transcriptionally silent upon infection of these cells over the course of seven days. In addition, we established an HHV-6-specific 4C-seq approach, revealing that the HHV-6A 3D interactome is associated with quiescent chromatin states in cells harboring integrated virus. Furthermore, we observed that the majority of virus chromatin interactions occur toward the distal ends of specific human chromosomes. Exploiting this finding, we established a 4C-seq method that accurately detects the chromosomal integration sites. We further implement long-read minION sequencing in the 4C-seq assay and developed a method to identify HHV-6A/B integration sites in clinical samples

Knowledge and behaviour regarding adverse effects of traditional biomass cookstove usage among rural households in desert frontline states of Northern Nigeria

Background: The adverse effects of traditional biomass cookstove (TBC) can be reduced by switching to cleaner cookstoves, improving cooking environment or changing cooking behaviour. Improved knowledge and behaviour regarding adverse effects of traditional biomass cookstove play a significant role in the success of any of the initiatives. This study evaluates the knowledge and behaviour regarding the adverse effects of TBC among rural households in selected desert frontline states of Nigeria.Materials and Methods: A cross-sectional study was conducted among rural households in selected communities in desert frontline states of Northern Nigeria between October, 2016 and January, 2017.The study administered pretested structured questionnaire to 392 households via house-to-house survey. The households were selected based on multistage sampling technique.Result: The findings revealed that majority of the households possess good knowledge regarding health and environmental effects (76.0%), hazards and injuries (94.1%) and drudgery and financial burden (91.8%) arising from TBC. Majority of them practice good behaviour to minimise these adverse effects (92.9%). It includes enclosing flames, use of dry fuel, and keeping children away while cooking. Taking precautions such as storing fuelwood far from the main building, ensuring there are ventilations for indoor kitchens and locating kitchens separately from main buildings are also considered in reducing adverse effects of TBC. Findings on households’ knowledge showed a significant association with behaviour towards adverse effects of TBC.Conclusion: It indicates that households have knowledge and approaches to reduce adverse effects of TBC. The study concluded that the households’ knowledge and behaviour signalling their efforts to reducing adverse effects of TBC. Thus, both are considered as the first step in facilitating cookstove improvement programmes. This information is an integral when designing and implementing sustainable intervention strategies for cookstove improvement, particularly in rural households of developing countries

The susceptibility of Varroa destructor against oxalic acid: A study case

Varroa destructor Anderson et Trueman is an ectoparasitic mite of the honey bee Apis mellifera L. and it must be controlled in managed bee colonies to maintain colony health. Taking into account that these mites are now resistant to synthetic acaricides worldwide, oxalic acid was suggested as an alternative for Varroa control. Oxalic acid is one of the most common natural miticides used against varroosis by spraying and sublimation administration techniques. It is a natural constituent of honey, very active against the Varroa mite, safe to use for beekeepers, and has no residue problems. Nevertheless, some authors have predicted that the risk of developing resistance to oxalic acid in mites is high. The objective of this research was to assess the susceptibility to oxalic acid of a V. destructor population belonging to a commercial apiary where 64 consecutive control treatments with this acid were performed. Bioassays to assess the oxalic acid susceptibility were performed on two mite populations: (1) a „focal‟ population consisting of mites previously exposed to oxalic acid treatments, and (2) a „naïve‟ population that was never exposed to this acid, which allows setting a reference in the absence of historical data on our „focal‟ mites. The results reported here suggest that the Varroa population exposed during 8 successive years to oxalic acid treatments remains susceptible to this acid.Fil: Maggi, Matías Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; ArgentinaFil: Damiani, Natalia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; ArgentinaFil: Ruffinengo, Sergio Roberto. Universidad Nacional de Mar del Plata. Facultad de Ciencias Agrarias. Departamento de Producción Animal. Cátedra de Apicultura; ArgentinaFil: Brasesco, Maria Constanza. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; ArgentinaFil: Szawarski, Nicolás. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Ministerio de Ciencia, Tecnología e Innovación Productiva. Agencia Nacional de Promoción Científica y Tecnológica. Fondo para la Investigación Científica y Tecnológica; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; ArgentinaFil: Mitton, Giulia Angelica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; ArgentinaFil: Mariani, Fernando. Beekeeping Consultant; ArgentinaFil: Sammataro, Diana. Carl Hayden Honey Bee Research Center; Estados UnidosFil: Quintana, Silvina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; Argentina. Fares Taie Instituto de Análisis; ArgentinaFil: Eguaras, Martin Javier. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Mar del Plata; Argentina. Universidad Nacional de Mar del Plata. Facultad de Ciencias Exactas y Naturales. Departamento de Biología. Laboratorio de Artrópodos; Argentin