Unilateral Eyelid Involvement as Single Presentation of Discoid Lupus Erythematosus: A Clinical Conundrum

We report a case of a 30-year-old woman with discoid lupus erythematosus (DLE) involving only a single lower eyelid. The diagnostic delay is explained by the unspecific clinical and histopathology picture and lack of specific changes in the first biopsy specimen taken. The diagnosis was based on later histological and immunological studies. Palpebral involvement has rarely been reported as the first and sole manifestation of the disease.</p

Unilateral Eyelid Involvement as Single Presentation of Discoid Lupus Erythematosus: A Clinical Conundrum

We report a case of a 30-year-old woman with discoid lupus erythematosus (DLE) involving only a single lower eyelid. The diagnostic delay is explained by the unspecific clinical and histopathology picture and lack of specific changes in the first biopsy specimen taken. The diagnosis was based on later histological and immunological studies. Palpebral involvement has rarely been reported as the first and sole manifestation of the disease.</p

Tracking soil particle deposition using bio-indication evidence and nondestructive FESEM and EDS analyses: A preliminary (pilot) study

The present study present chemometric bioindication methodology for fast and effective monitoring in long distant distribution of top soil pollution and evidence for element soil dust deposition. Both varieties of Briophytes, Hypnum cupressiforme (Hedw.) and Homalothecium lutescens (Hedw.) has been used for improving the effective nondestructive bio-indication. Although mosses do not have a root system, influence from soil dusting cannot be disregarded, in praticular in areas with windblown mineral dust from local soil. As far as the surface bound fraction is concerned, little is known about the binding mechanisms, but the fact that different metals show rather large differences in their retention capacities, indicates that both simple cation exchange on negative surface charges and complex formation with ligands on the moss surface are involved. Laboratory analysis, using field emission scanning electron microscopy (FESEM) and energy dispersive X-ray spectrometer (EDS) has been involved for determination of the dry deposition occurred within moss biomonitors. The bioindication chemometric model was improved for nondestuctive evidence effectively for biogenic elements carbon and oxygen, macroelements Mg, Al, Si, K, Ca, and microelements Fe, Cu and Zn. Both moss species can be used interchangeable for dust deposition investigation

Rowell\u27s syndrome triggered by omeprazole

No abstract available</p

Universities as catalysts of social innovation in health systems in low-and middle-income countries: a multi-country case study.

BACKGROUND: Social innovation (SI) in health holds potential to contribute to health systems strengthening and universal health coverage (UHC). The role of universities in SI has been well described in the context of high-income countries. An evidence gap exits on SI in healthcare delivery in the context of low- and middle-income countries (LMICs) as well as on the engagement of universities from these contexts. There is thus a need to build capacity for research and engagement in SI in healthcare delivery within these universities. The aim of this study was to examine the adoption and implementation of network of university hubs focused on SI in healthcare delivery within five countries across Africa, Asia and Latin America. The objectives were to describe the model, components and implementation process of the hubs; identify the enablers and barriers experienced and draw implications that could be relevant to other LMIC universities interested in SI. METHODS: A case study design was adopted to study the implementation process of a network of university hubs. Data from documentation, team discussions and post-implementation surveys were collected from 2013 to 2018 and analysed with aid of a modified policy analysis framework. RESULTS/DISCUSSION: SI university-based hubs serve as cross-disciplinary and cross-sectoral platforms, established to catalyse SI within the local health system through four core activities: research, community-building, storytelling and institutional embedding, and adhering to values of inclusion, assets, co-creation and hope. Hubs were implemented as informal structures, managed by a small core team, in existing department. Enablers of hub implementation and functioning were the availability of strong in-country social networks, legitimacy attained from being part of a global network on SI in health and receiving a capacity building package in the initial stages. Barriers encountered were internal institutional resistance, administrative challenges associated with university bureaucracy and annual funding cycles. CONCLUSIONS: This case study shows the opportunity that reside within LMIC universities to act as eco-system enablers of SI in healthcare delivery in order to fill the evidence gap on SI and enhance cross-sectoral participation in support of achieving UHC

Emotional experiences and psychological well-being in 51 countries during the covid-19 pandemic

The COVID-19 pandemic presents challenges to psychological well-being, but how can we predict when people suffer or cope during sustained stress? Here, we test the prediction that specific types of momentary emotional experiences are differently linked to psychological well-being during the pandemic. Study 1 used survey data collected from 24,221 participants in 51 countries during the COVID-19 outbreak. We show that, across countries, well-being is linked to individuals’ recent emotional experiences, including calm, hope, anxiety, loneliness, and sadness. Consistent results are found in two age, sex, and ethnicity-representative samples in the United Kingdom (n = 971) and the United States (n = 961) with preregistered analyses (Study 2). A prospective 30-day daily diary study conducted in the United Kingdom (n = 110) confirms the key role of these five emotions and demonstrates that emotional experiences precede changes in well-being (Study 3). Our findings highlight differential relationships between specific types of momentary emotional experiences and well-being and point to the cultivation of calm and hope as candidate routes for well-being interventions during periods of sustained stress