68 research outputs found

    Self-assessed intelligence, personality, and psychometric intelligence: preliminary validation of a model with a selected student population

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    In the current study, self-assessed intelligence (SAI) is presented as a multidimensionalconstruct related both to personality and to psychometric intelligence. Onthe basis of data obtained from a Russian student sample (N = 496), the authorsvalidate a structural model in which SAI acts as a mediating variable between latentvariables of measured IQ and the trait of acceptance of uncertainty. Evidencefor signifi cant gender diff erences in SAI in favor of men is also given

    Retrospective perception of bulling in students: socio-economic, gender and family factors

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    Background. The paper presents results of a study about perception of school bulling among Russian students. Being a type of aggressive behavior, bullying needs to be interrupted by psychologists, teachers and parents, preventive intervention is also required. However, there are few studies about dynamics of bulling perception in males and females a few years after graduation. It is during this period that not only participation, but also the intensity of the experience of school bullying as a significant event of the past, can affect the further choice of a career, success in life, and psychological and emotional state. Objective. The study is aimed at solving several problems. The prevalence of different types of bullying (social aggression, verbal bullying, physical bullying, cyberbullying) in high school was analyzed, and bullying was assessed in terms of the distribution of roles. We also studied the influence of socio-demographic factors of bullying and conducted a comparative analysis of two age groups (high school students and primary school students) and a retrospective analysis of students’ perception of school bullying. Design. The sample included 700 junior students from a number of Russian cities (males – 12%; females – 88%). During the research, the following methods were used: online questionnaire, methods for evaluating bullying (Adolescent Peer Relation Instrument, Social Bullying Involvement Scales, Cyberbullying and Online Aggression Survey). Findings show, that every second school student took part in school bulling, and there are positive correlations between bulling roles (aggressor, victim, witness). There are gender and socio-economic differences between respondents who were involved in bulling or avoided participation in bullying. With age, there is a tendency to decrease the number of respondents who participated in physical bullying, however, there is still a high percentage of participation in other types of bullying. Conclusion. High level of adolescent bulling underscores the necessity of preventive intervention at school of including teenagers in bulling underscores the necessary of preventive intervention at schools

    Comportamiento destructivo de una persona en retrospectiva histórica: factores, diagnóstico y prevención

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    In conditions of the current development of society which is characterized by mounting social, economic and political crises, the problem of destructive behavior of an individual acquires special significance and topicality. The paper presents the results of a theoretical and methodological analysis of this problem in foreign and domestic literature in several areas: analysis of the attitude of society towards destructive behavior in its historical aspect; philosophical and theological approach; sociological and demographic areas in the study of destructive behavior, biological and biochemical; genetic approaches; psychological and socio-psychological aspects in the study of destructive behavior of a person. In view of the analysis of various approaches and areas in the study of destructive behavior, the conclusions have been drawn that destructive behavior is represented as a complex phenomenon, caused by biological factors (genetic predisposition, constitutional features of the body structure, the use of psychoactive substances, etc.), social (economic and social crises ), psychopathological (connection with mental disorders), psychological (especially the system of needs and motives of activity), socio-psychological (the impact of socio-psychological maladaptation and characteristics of the values and meaning sphere of an individual) plans. These factors are interconnected and each of them has its own specific role in the complex of destructive behavior, and therefore it is impossible to obtain a holistic view of the phenomenon under consideration taken separately from the entire system of interconnected components.En las condiciones del desarrollo actual de la sociedad, que se caracteriza por el aumento de las crisis sociales, económicas y políticas, el problema del comportamiento destructivo de un individuo adquiere un significado especial y actualidad. El artículo presenta los resultados de un análisis teórico y metodológico de este problema en la literatura extranjera y nacional en varias áreas: análisis de la actitud de la sociedad hacia el comportamiento destructivo en su aspecto histórico; enfoque filosófico y teológico; áreas sociológicas y demográficas en el estudio del comportamiento destructivo, biológico y bioquímico; enfoques genéticos; Aspectos psicológicos y socio-psicológicos en el estudio del comportamiento destructivo de una persona. En vista del análisis de varios enfoques y áreas en el estudio del comportamiento destructivo, se ha llegado a la conclusión de que el comportamiento destructivo se representa como un fenómeno complejo, causado por factores biológicos (predisposición genética, características constitucionales de la estructura del cuerpo, el uso de sustancias psicoactivas, etc.), sociales (crisis económicas y sociales), psicopatológicas (conexión con trastornos mentales), psicológicas (especialmente el sistema de necesidades y motivos de actividad), sociopsicológicas (el impacto de la mala adaptación sociopsicológica y las características de los valores y la esfera de significado de un individuo) planes. Estos factores están interconectados y cada uno de ellos tiene su propio papel específico en el complejo del comportamiento destructivo y, por lo tanto, es imposible obtener una visión holística del fenómeno en consideración tomado por separado del sistema completo de componentes interconectados

    Arc/Arg3.1 expression in the brain tissues during the learning process in Alzheimer's disease animal models

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    Introduction. Arc/Arg3.1 is a common marker of neuronal activation for learning and memorizing. Some experimental data show the Arc/Arg3.1 expression in the post-mitotic neurons of the neurogenic niches. At the same time, we still have to understand the importance of such an expression for neurogenesis induced by the learning or memorizing processes, in health and in disease. Objective: to evaluate the changes in Arc/Arg3.1 expression in the post-mitotic neurons and to assess the proliferative activity of the neurogenic niche cells in Alzheimer's disease animal models. Materials and methods. We divided the C57Bl/6В mice into 2 groups: experimental (n = 15) and control (n = 15). The experimental group were injected with the amyloid- oligomers 2535 in their CA1 hippocampal region while the control mice received normal saline injections in the same region. Passive Avoidance Test (PAT) was used to assess the cognitive functions from the day 9 after the intervention. One hour after each test session we collected the samples of brain tissues to immunohistochemically assess them for the Arc/Arg3.1 expression and PCNA cell proliferation marker. Results. At day 11 the count of Arc/Arg3.1+NeuN+ cells in the subgranular zone had significantly increased. In animal neurodegeneration models the 1st and 2nd PAT sessions were associated with a significant increase in Arc/Arg3.1+NeuN+ cells, although by the day 11 their count significantly decreased. The count of Arc/Arg3.1+ cells in the subventricular and subgranular zones had increased after the 3rd PAT session in the control group while in Alzheimer's disease animal models this was observed only after the 2nd PAT session. Preserved Arc/Arg3.1 expression in the subventricular zone is associated with the increased PCNA cell prolifera- tion marker expression. At the same time, the toxic effect of the amyloid- oligomers suppressed the cells' proliferative activity in the subgranular zone at day 9. Conclusions. Despite the toxic effect of the amyloid- oligomers 2535, the post-mitotic neurons of the neurogenic niches retained the ability to express Arc/Arg3.1 in vivo. The obtained results show a transient increase in sensitivity of the post-mitotic neurons of the neurogenic niches for the learning stimuli in the early stages of the Alzheimer-type neurodegeneration

    Destructive Behavior of a Person in Historical Retrospective: Factors, Diagnosis and Prevention

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    En las condiciones del desarrollo actual de la sociedad, que se caracteriza por el aumento de las crisis sociales, económicas y políticas, el problema del comportamiento destructivo de un individuo adquiere un significado especial y actualidad. El artículo presenta los resultados de un análisis teórico y metodológico de este problema en la literatura extranjera y nacional en varias áreas: análisis de la actitud de la sociedad hacia el comportamiento destructivo en su aspecto histórico; enfoque filosófico y teológico; áreas sociológicas y demográficas en el estudio del comportamiento destructivo, biológico y bioquímico; enfoques genéticos; Aspectos psicológicos y socio-psicológicos en el estudio del comportamiento destructivo de una persona. En vista del análisis de varios enfoques y áreas en el estudio del comportamiento destructivo, se ha llegado a la conclusión de que el comportamiento destructivo se representa como un fenómeno complejo, causado por factores biológicos (predisposición genética, características constitucionales de la estructura del cuerpo, el uso de sustancias psicoactivas, etc.), sociales (crisis económicas y sociales), psicopatológicas (conexión con trastornos mentales), psicológicas (especialmente el sistema de necesidades y motivos de actividad), sociopsicológicas (el impacto de la mala adaptación sociopsicológica y las características de los valores y la esfera de significado de un individuo) planes. Estos factores están interconectados y cada uno de ellos tiene su propio papel específico en el complejo del comportamiento destructivo y, por lo tanto, es imposible obtener una visión holística del fenómeno en consideración tomado por separado del sistema completo de componentes interconectados.In conditions of the current development of society which is characterized by mounting social, economic and political crises, the problem of destructive behavior of an individual acquires special significance and topicality. The paper presents the results of a theoretical and methodological analysis of this problem in foreign and domestic literature in several areas: analysis of the attitude of society towards destructive behavior in its historical aspect; philosophical and theological approach; sociological and demographic areas in the study of destructive behavior, biological and biochemical; genetic approaches; psychological and socio-psychological aspects in the study of destructive behavior of a person. In view of the analysis of various approaches and areas in the study of destructive behavior, the conclusions have been drawn that destructive behavior is represented as a complex phenomenon, caused by biological factors (genetic predisposition, constitutional features of the body structure, the use of psychoactive substances, etc.), social (economic and social crises ), psychopathological (connection with mental disorders), psychological (especially the system of needs and motives of activity), socio-psychological (the impact of socio-psychological maladaptation and characteristics of the values and meaning sphere of an individual) plans. These factors are interconnected and each of them has its own specific role in the complex of destructive behavior, and therefore it is impossible to obtain a holistic view of the phenomenon under consideration taken separately from the entire system of interconnected components

    Spectroscopic ellipsometry and polarimetry for materials and systems analysis at the nanometer scale: state-of-the-art, potential, and perspectives

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    This paper discusses the fundamentals, applications, potential, limitations, and future perspectives of polarized light reflection techniques for the characterization of materials and related systems and devices at the nanoscale. These techniques include spectroscopic ellipsometry, polarimetry, and reflectance anisotropy. We give an overview of the various ellipsometry strategies for the measurement and analysis of nanometric films, metal nanoparticles and nanowires, semiconductor nanocrystals, and submicron periodic structures. We show that ellipsometry is capable of more than the determination of thickness and optical properties, and it can be exploited to gain information about process control, geometry factors, anisotropy, defects, and quantum confinement effects of nanostructures

    Impact of renal impairment on atrial fibrillation: ESC-EHRA EORP-AF Long-Term General Registry

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    Background: Atrial fibrillation (AF) and renal impairment share a bidirectional relationship with important pathophysiological interactions. We evaluated the impact of renal impairment in a contemporary cohort of patients with AF. Methods: We utilised the ESC-EHRA EORP-AF Long-Term General Registry. Outcomes were analysed according to renal function by CKD-EPI equation. The primary endpoint was a composite of thromboembolism, major bleeding, acute coronary syndrome and all-cause death. Secondary endpoints were each of these separately including ischaemic stroke, haemorrhagic event, intracranial haemorrhage, cardiovascular death and hospital admission. Results: A total of 9306 patients were included. The distribution of patients with no, mild, moderate and severe renal impairment at baseline were 16.9%, 49.3%, 30% and 3.8%, respectively. AF patients with impaired renal function were older, more likely to be females, had worse cardiac imaging parameters and multiple comorbidities. Among patients with an indication for anticoagulation, prescription of these agents was reduced in those with severe renal impairment, p <.001. Over 24 months, impaired renal function was associated with significantly greater incidence of the primary composite outcome and all secondary outcomes. Multivariable Cox regression analysis demonstrated an inverse relationship between eGFR and the primary outcome (HR 1.07 [95% CI, 1.01–1.14] per 10 ml/min/1.73 m2 decrease), that was most notable in patients with eGFR <30 ml/min/1.73 m2 (HR 2.21 [95% CI, 1.23–3.99] compared to eGFR ≥90 ml/min/1.73 m2). Conclusion: A significant proportion of patients with AF suffer from concomitant renal impairment which impacts their overall management. Furthermore, renal impairment is an independent predictor of major adverse events including thromboembolism, major bleeding, acute coronary syndrome and all-cause death in patients with AF

    Clinical complexity and impact of the ABC (Atrial fibrillation Better Care) pathway in patients with atrial fibrillation: a report from the ESC-EHRA EURObservational Research Programme in AF General Long-Term Registry

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    Background: Clinical complexity is increasingly prevalent among patients with atrial fibrillation (AF). The ‘Atrial fibrillation Better Care’ (ABC) pathway approach has been proposed to streamline a more holistic and integrated approach to AF care; however, there are limited data on its usefulness among clinically complex patients. We aim to determine the impact of ABC pathway in a contemporary cohort of clinically complex AF patients. Methods: From the ESC-EHRA EORP-AF General Long-Term Registry, we analysed clinically complex AF patients, defined as the presence of frailty, multimorbidity and/or polypharmacy. A K-medoids cluster analysis was performed to identify different groups of clinical complexity. The impact of an ABC-adherent approach on major outcomes was analysed through Cox-regression analyses and delay of event (DoE) analyses. Results: Among 9966 AF patients included, 8289 (83.1%) were clinically complex. Adherence to the ABC pathway in the clinically complex group reduced the risk of all-cause death (adjusted HR [aHR]: 0.72, 95%CI 0.58–0.91), major adverse cardiovascular events (MACEs; aHR: 0.68, 95%CI 0.52–0.87) and composite outcome (aHR: 0.70, 95%CI: 0.58–0.85). Adherence to the ABC pathway was associated with a significant reduction in the risk of death (aHR: 0.74, 95%CI 0.56–0.98) and composite outcome (aHR: 0.76, 95%CI 0.60–0.96) also in the high-complexity cluster; similar trends were observed for MACEs. In DoE analyses, an ABC-adherent approach resulted in significant gains in event-free survival for all the outcomes investigated in clinically complex patients. Based on absolute risk reduction at 1 year of follow-up, the number needed to treat for ABC pathway adherence was 24 for all-cause death, 31 for MACEs and 20 for the composite outcome. Conclusions: An ABC-adherent approach reduces the risk of major outcomes in clinically complex AF patients. Ensuring adherence to the ABC pathway is essential to improve clinical outcomes among clinically complex AF patients

    Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Research Programme in AF (EORP-AF) General Long-Term Registry

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    Background: Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients\u2019 clinical phenotypes and analyse the differential clinical course. Methods: We performed a hierarchical cluster analysis based on Ward\u2019s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results: A total of 9363 were available for this analysis. We identified three clusters: Cluster 1 (n = 3634; 38.8%) characterized by older patients and prevalent non-cardiac comorbidities; Cluster 2 (n = 2774; 29.6%) characterized by younger patients with low prevalence of comorbidities; Cluster 3 (n = 2955;31.6%) characterized by patients\u2019 prevalent cardiovascular risk factors/comorbidities. Over a mean follow-up of 22.5 months, Cluster 3 had the highest rate of cardiovascular events, all-cause death, and the composite outcome (combining the previous two) compared to Cluster 1 and Cluster 2 (all P <.001). An adjusted Cox regression showed that compared to Cluster 2, Cluster 3 (hazard ratio (HR) 2.87, 95% confidence interval (CI) 2.27\u20133.62; HR 3.42, 95%CI 2.72\u20134.31; HR 2.79, 95%CI 2.32\u20133.35), and Cluster 1 (HR 1.88, 95%CI 1.48\u20132.38; HR 2.50, 95%CI 1.98\u20133.15; HR 2.09, 95%CI 1.74\u20132.51) reported a higher risk for the three outcomes respectively. Conclusions: In European AF patients, three main clusters were identified, differentiated by differential presence of comorbidities. Both non-cardiac and cardiac comorbidities clusters were found to be associated with an increased risk of major adverse outcomes
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