Additional file 2: of An evaluation of the DEXLIFE ‘self-selected’ lifestyle intervention aimed at improving insulin sensitivity in people at risk of developing type 2 diabetes: study protocol for a randomised controlled trial

Participant flow through the recruitment process. (PDF 170 kb

Fasting plasma glucose as initial screening for diabetes and prediabetes in irish adults: The Diabetes Mellitus and Vascular health initiative (DMVhi).

Type 2 diabetes has a long pre clinical asymptomatic phase. Early detection may delay or arrest disease progression. The Diabetes Mellitus and Vascular health initiative (DMVhi) was initiated as a prospective longitudinal cohort study on the prevalence of undiagnosed Type 2 diabetes and prediabetes, diabetes risk and cardiovascular risk in a cohort of Irish adults aged 45-75 years

DMVhi study participant characteristics by glucose tolerance status (n = 29,144).

<p>*Mean value,</p><p>^§ abdominal obesity defined as waist circumference of ≥80cm in females and ≥94cm in males. BP = blood pressure, T2D = type 2 diabetes,</p><p>DMVhi study participant characteristics by glucose tolerance status (n = 29,144).</p

DMVhi cohort age-group and gender-specific prevalence rates of undiagnosed type 2 diabetes, impaired glucose tolerance and impaired fasting glucose (n = 29,144; male = 12,929 (44%); female = 16,215 (56%)).

<p>T2D = type 2 diabetes, IGT = impaired glucose tolerance and IFG = impaired fasting glucose. Gender differences for DMVhi cohort and for each age group: p<0.001</p><p>DMVhi cohort age-group and gender-specific prevalence rates of undiagnosed type 2 diabetes, impaired glucose tolerance and impaired fasting glucose (n = 29,144; male = 12,929 (44%); female = 16,215 (56%)).</p

Results of DMVhi screening for undiagnosed type 2 diabetes, impaired fasting glucose and impaired glucose tolerance (March 2009-December 2012).

<p>RFG = repeat fasting glucose, IGT = impaired glucose tolerance, IFG = impaired fasting glucose, OGTT = oral glucose tolerance test. *Participants were not deemed to have completed screening if they did not return for required OGTT/RFG (n = 322) or did not provide a venous fasting sample (n = 82). ** Diagnosed with diabetes on fasting blood glucose (≥7.0 mmol/L) and symptoms of diabetes.</p

DMVhi study participant characteristics by glucose tolerance status (n = 29,144).

<p>*Mean value,</p><p>^§ abdominal obesity defined as waist circumference of ≥80cm in females and ≥94cm in males. BP = blood pressure, T2D = type 2 diabetes,</p><p>DMVhi study participant characteristics by glucose tolerance status (n = 29,144).</p