Use of fairy tales to the development of socialization of children of primary school age

Katedra pedagogikyPedagogická fakultaFaculty of Educatio

Projektové vyučování ve výuce odborných předmětů učebního oboru zedník a instalatér

This work consideres a popssibility of increasing quality, effectivity and attractivity of teaching vocational subjects of technical apprenticeships, in particular of the bricklayer and plumber branches, by the incorporation of project teaching. It seems that the apprenticeship education got stuck in the aged teaching approaches. At the same time, high quality textbooks reflecting the current rapidly evolving trends in new technological processes and technical materials are lacking. The project teaching method could bring improvements in competences of apprentice students, mainly adaptability, responsibility and team-work skills, which are required by their future employers. The theoretical part of the work briefly describes the project teaching method. Further, it focuses on developmental aspects of the target student group, which is the age category from 15 to 20-22 years, the adolescence, primarily boys. The practical part of the work describes a proposal of a specific educational project for the third year of apprenticeship branch bricklayer and plumber. With regard to the ongoing restriction at schools during the school year 2020/2021 caused by the coronavirus pandemic, the proposer project can not be directly used in practice at this time

E-commerce

This work studies factors of e-shops credibility on the field B2C. The aim of the work was to work out a summary of recommendations for businessmen, who deal with or consider internet marketing, and to introduce particular suggestions for a specific e-shop

Use of fairy tales to the development of socialization of children of primary school age

Katedra pedagogikyPedagogická fakultaFaculty of Educatio

Risk Factors for Nonadherence to Antihypertensive Treatment

Nonadherence to antihypertensive treatment is a critical contributor to suboptimal blood pressure control. There are limited and heterogeneous data on the risk factors for nonadherence because few studies used objective-direct diagnostic methods. We used high-performance liquid chromatography-tandem mass spectrometry of urine and serum to detect nonadherence and explored its association with the main demographic- and therapy-related factors in 1348 patients with hypertension from 2 European countries. The rates of nonadherence to antihypertensive treatment were 41.6% and 31.5% in the UK and Czech populations, respectively. Nonadherence was inversely related to age and male sex. Each increase in the number of antihypertensive medications led to 85% and 77% increase in nonadherence ( P &lt;0.001) in the UK and Czech populations, respectively. The odds of nonadherence to diuretics were the highest among 5 classes of antihypertensive medications ( P ≤0.005 in both populations). The predictive model for nonadherence, including age, sex, diuretics, and the number of prescribed antihypertensives, showed area under the curves of 0.758 and 0.710 in the UK and Czech populations, respectively. The area under the curves for the UK model tested on the Czech data and for the Czech model tested on UK data were calculated at 0.708 and 0.756, respectively. We demonstrate that the number and class of prescribed antihypertensives are modifiable risk factors for biochemically confirmed nonadherence to blood pressure–lowering therapy. Further development of discriminatory models incorporating these parameters might prove clinically useful in assessment of nonadherence in countries where biochemical analysis is unavailable. </jats:p

Biochemical Screening for Nonadherence Is Associated With Blood Pressure Reduction and Improvement in Adherence.

We hypothesized that screening for nonadherence to antihypertensive treatment using liquid chromatography-tandem mass spectrometry-based biochemical analysis of urine/serum has therapeutic applications in nonadherent hypertensive patients. A retrospective analysis of hypertensive patients attending specialist tertiary care centers was conducted in 2 European countries (United Kingdom and Czech Republic). Nonadherence to antihypertensive treatment was diagnosed using biochemical analysis of urine (United Kingdom) or serum (Czech Republic). These results were subsequently discussed with each patient, and data on follow-up clinic blood pressure (BP) measurements were collected from clinical files. Of 238 UK patients who underwent biochemical urine analysis, 73 were nonadherent to antihypertensive treatment. Their initial urinary adherence ratio (the ratio of detected to prescribed antihypertensive medications) increased from 0.33 (0-0.67) to 1 (0.67-1) between the first and the last clinic appointments. The observed increase in the urinary adherence ratio in initially nonadherent UK patients was associated with the improved BP control; by the last clinic appointment, systolic and diastolic BPs were ≈19.5 and 7.5 mm Hg lower than at baseline (P=0.001 and 0.009, respectively). These findings were further corroborated in 93 nonadherent hypertensive patients from Czech Republic-their average systolic and diastolic BPs dropped by ≈32.6 and 17.4 mm Hg, respectively (P<0.001), on appointments after the biochemical analysis. Our data show that nonadherent hypertensive patients respond to liquid chromatography-tandem mass spectrometry-based biochemical analysis with improved adherence and significant BP drop. Such repeated biochemical analyses should be considered as a therapeutic approach in nonadherent hypertensive patients