14,934 research outputs found

    The dynamic analysis of submerged structures

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    Methods are described by which the dynamic interaction of structures with surrounding fluids can be computed by using finite element techniques. In all cases, the fluid is assumed to behave as an acoustic medium and is initially stationary. Such problems are solved either by explicitly modeling the fluid (using pressure or displacement as the basic fluid unknown) or by using decoupling approximations which take account of the fluid effects without actually modeling the fluid

    Quantifying innovation in surgery

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    Objectives: The objectives of this study were to assess the applicability of patents and publications as metrics of surgical technology and innovation; evaluate the historical relationship between patents and publications; develop a methodology that can be used to determine the rate of innovation growth in any given health care technology. Background: The study of health care innovation represents an emerging academic field, yet it is limited by a lack of valid scientific methods for quantitative analysis. This article explores and cross-validates 2 innovation metrics using surgical technology as an exemplar. Methods: Electronic patenting databases and the MEDLINE database were searched between 1980 and 2010 for “surgeon” OR “surgical” OR “surgery.” Resulting patent codes were grouped into technology clusters. Growth curves were plotted for these technology clusters to establish the rate and characteristics of growth. Results: The initial search retrieved 52,046 patents and 1,801,075 publications. The top performing technology cluster of the last 30 years was minimally invasive surgery. Robotic surgery, surgical staplers, and image guidance were the most emergent technology clusters. When examining the growth curves for these clusters they were found to follow an S-shaped pattern of growth, with the emergent technologies lying on the exponential phases of their respective growth curves. In addition, publication and patent counts were closely correlated in areas of technology expansion. Conclusions: This article demonstrates the utility of publically available patent and publication data to quantify innovations within surgical technology and proposes a novel methodology for assessing and forecasting areas of technological innovation

    Low mass dimuons within a hybrid approach

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    We analyse dilepton emission from hot and dense hadronic matter using a hybrid approach based on the Ultrarelativistic Quantum Molecular Dynamics (UrQMD) transport model with an intermediate hydrodynamic stage for the description of heavy-ion collisions at relativistic energies. Focusing on the enhancement with respect to the contribution from long-lived hadron decays after freeze-out observed at the SPS in the low mass region of the dilepton spectra (often referred to as "the excess"), the relative importance of the emission from the equilibrium and the non-equilibrium stages is discussed.Comment: Proceedings of Hot Quarks 2010, 21-26 June 2010 Las Londe Les Maures; v2: Corrected typos and added a commen

    Distance statistics in quadrangulations with a boundary, or with a self-avoiding loop

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    We consider quadrangulations with a boundary and derive explicit expressions for the generating functions of these maps with either a marked vertex at a prescribed distance from the boundary, or two boundary vertices at a prescribed mutual distance in the map. For large maps, this yields explicit formulas for the bulk-boundary and boundary-boundary correlators in the various encountered scaling regimes: a small boundary, a dense boundary and a critical boundary regime. The critical boundary regime is characterized by a one-parameter family of scaling functions interpolating between the Brownian map and the Brownian Continuum Random Tree. We discuss the cases of both generic and self-avoiding boundaries, which are shown to share the same universal scaling limit. We finally address the question of the bulk-loop distance statistics in the context of planar quadrangulations equipped with a self-avoiding loop. Here again, a new family of scaling functions describing critical loops is discovered.Comment: 55 pages, 14 figures, final version with minor correction

    Diffusion-controlled generation of a proton-motive force across a biomembrane

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    Respiration in bacteria involves a sequence of energetically-coupled electron and proton transfers creating an electrochemical gradient of protons (a proton-motive force) across the inner bacterial membrane. With a simple kinetic model we analyze a redox loop mechanism of proton-motive force generation mediated by a molecular shuttle diffusing inside the membrane. This model, which includes six electron-binding and two proton-binding sites, reflects the main features of nitrate respiration in E. coli bacteria. We describe the time evolution of the proton translocation process. We find that the electron-proton electrostatic coupling on the shuttle plays a significant role in the process of energy conversion between electron and proton components. We determine the conditions where the redox loop mechanism is able to translocate protons against the transmembrane voltage gradient above 200 mV with a thermodynamic efficiency of about 37%, in the physiologically important range of temperatures from 250 to 350 K.Comment: 26 pages, 4 figures. A similar model is used in arXiv:0806.3233 for a different biological system. Minor changes in the Acknowledgements sectio

    Coin Tossing as a Billiard Problem

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    We demonstrate that the free motion of any two-dimensional rigid body colliding elastically with two parallel, flat walls is equivalent to a billiard system. Using this equivalence, we analyze the integrable and chaotic properties of this new class of billiards. This provides a demonstration that coin tossing, the prototypical example of an independent random process, is a completely chaotic (Bernoulli) problem. The related question of which billiard geometries can be represented as rigid body systems is examined.Comment: 16 pages, LaTe

    Confluence of geodesic paths and separating loops in large planar quadrangulations

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    We consider planar quadrangulations with three marked vertices and discuss the geometry of triangles made of three geodesic paths joining them. We also study the geometry of minimal separating loops, i.e. paths of minimal length among all closed paths passing by one of the three vertices and separating the two others in the quadrangulation. We concentrate on the universal scaling limit of large quadrangulations, also known as the Brownian map, where pairs of geodesic paths or minimal separating loops have common parts of non-zero macroscopic length. This is the phenomenon of confluence, which distinguishes the geometry of random quadrangulations from that of smooth surfaces. We characterize the universal probability distribution for the lengths of these common parts.Comment: 48 pages, 33 color figures. Final version, with one concluding paragraph and one reference added, and several other small correction

    Gravitational waves from Extreme Mass Ratio Inspirals in non-pure Kerr spacetimes

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    To investigate the imprint on the gravitational-wave emission from extreme mass-ratio inspirals in non-pure Kerr spacetimes, we have studied the ``kludge'' waveforms generated in highly-accurate, numerically-generated spacetimes containing a black hole and a self-gravitating, homogeneous torus with comparable mass and spin. In order to maximize their impact on the produced waveforms, we have considered tori that are compact, massive and close to the central black hole, investigating under what conditions the LISA experiment could detect their presence. Our results show that for a large portion of the space of parameters the waveforms produced by EMRIs in these black hole-torus systems are indistinguishable from pure-Kerr waveforms. Hence, a ``confusion problem'' will be present for observations carried out over a timescale below or comparable to the dephasing time.Comment: 21 pages, 12 figures. Short discussion on the accuracy of the spacetimes added, typos corrected. Accepted for publication in PR
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