Knowledge and Attitudes of GPs in Saxony-Anhalt concerning the Psychological Aspects of Bronchial Asthma: A Questionnaire Study

Bronchial Asthma is a worldwide condition with particularly high prevalence in first world countries. The reasons are multifactorial but a neglected area is the psychological domain. It is well known that heavy emotions can trigger attacks and that depression negatively affects treatment outcomes. It is also known that personality type has a greater effect on disease prevalence than in many other conditions. However, many potential psychological treatments are hardly considered, neither in treatment guidelines nor in reviews by asthma specialists. Moreover, there is very little research concerning the beliefs and practices of doctors regarding psychological treatments. Using a questionnaire survey we ascertained that local GPs in Saxony-Anhalt have reasonably good knowledge about the psychological elements of asthma; a third consider it to be some of the influence (20-40% aetiology) and a further third consider it to be even more important than that (at least 40% total aetiology). Our GPs use psychosomatic counseling sometimes or usually in the areas of sport and smoking (circa 85% GPs), although less so regarding breathing techniques and relaxation (c40% usually or sometimes do this) However despite this knowledge they refer to the relevant clinicians very rarely (98% sometimes, usually or always refer to a respiratory physician compared with only 11% referring for psychological help)

Wirtschaftlichkeit der Hahnenmast in Zweinutzungshuhn- und „Bruderhahn“-Konzepten unter Berücksichtigung von Verarbeitungs- und Vermarktungsaspekten

Aufgrund der zunehmenden Diskussion um den Tierschutz ist das Töten männlicher Küken der Legeherkünfte aus tierethischer, gesellschaftlicher wie politischer Sicht kaum mehr vertretbar. Im Rahmen eines Forschungsprojektes, finanziert durch das Ministerium für Klimaschutz, Umwelt, Landwirtschaft, Natur- und Verbraucherschutz des Landes Nordrhein-Westfalen, untersuchte die Fachhochschule Südwestfalen das Marktpotential von Fleisch- und Wurstwaren männlicher Lege- und Zweinutzungshybride bei 10- und 20-wöchiger Mast. Es wurde dabei der Frage nachgegangen, inwieweit und unter welchen Bedingungen nachhaltige Erzeugungs-, Verarbeitungs- und Vermarktungsprozesse für den Geflügelsektor aufgebaut werden können, um auf das Töten der Hahnenküken verzichten zu können. Die Ergebnisse zeigen, dass für eine wirtschaftlich erfolgreiche Mast der Lege- und Zweinutzungshybriden eine hochwertige Vermarktung unabdingbar ist. Interessante produktpolitische Vermarktungsperspektiven ergeben sich für Dauerwurstwaren wie Salami. Die Mast der Zweinutzungshähne kann wirtschaftlich ohne Querfinanzierung über die Eier erreicht werden, wenn das Fleisch und die Wurstwaren im Bio-Marktsegment positioniert werden. Insgesamt ergeben sich durch die Herstellung hochwertiger Fleisch- und Wurstprodukte aus Lege- und Zweinutzungshähnen und die Einbettung in neuartige Vermarktungsmodelle mit passenden Marktpositionierungen realistische Perspektiven

The KATRIN Experiment

The KArlsruhe TRitium Neutrino mass experiment, KATRIN, aims to search for the mass of the electron neutrino with a sensitivity of 0.2 eV/c^2 (90% C.L.) and a detection limit of 0.35 eV/c^2 (5 sigma). Both a positive or a negative result will have far reaching implications for cosmology and the standard model of particle physics and will give new input for astroparticle physics and cosmology. The major components of KATRIN are being set up at the Karlsruhe Institut of Technology in Karlsruhe, Germany, and test measurements of the individual components have started. Data taking with tritium is scheduled to start in 2012.Comment: 3 pages, 1 figure, proceedings of the TAUP 2009 International Conference on Topics in Astroparticle and Underground Physics, to be published in Journal of Physics, Conference Serie

The Promotion of Sustainable Supply Chains through German Development Cooperation based on the Example of the Textile Sector

German development cooperation is pursuing the objective of reducing negative social and environmental effects in global (textile) supply chains and thus, in the long term, contributing to designing them more sustainably. This evaluation examines, in particular, the interaction between various development cooperation instruments and measures to promote sustainable global supply chains in the textile sector

Leishmania siamensis als Erreger von autochthoner kutaner Leishmaniose bei Pferden in Deutschland - eine neue Infektionskrankheit in Mitteleuropa?

Aus mitteleuropäischer Sicht ist die durch Parasiten verursachte und von Sandmücken übertragene Leishmaniose eine in Ländern tropischer und subtropischer Regionen auftretende Infektionskrankheit. In zunehmendem Maße werden jedoch autochthone Fälle in Mitteleuropa, insbesondere in Süddeutschland, verzeichnet. Dies ist vermutlich auf die globale Erwärmung und die Ausdehnung des Verbreitungsgebietes der Sandmücken nach Norden zurückzuführen. Die vorliegende Arbeit befasst sich mit der Identifizierung und phylogenetischen Charakterisierung der Erreger dieser Fälle. Dazu wurden verschiedene Marker im Leishmaniengenom sequenziert und mit bekannten Arten verglichen. Die untersuchte DNA stammte von autochthonen kutanen Leishmaniosen bei Pferden und einem Rind, die in den letzten zehn Jahren in Deutschland und der Schweiz auftraten. Aufgrund identischer Sequenzen konnten die Parasiten als L. siamensis identifiziert bzw. verifiziert werden, eine erst im Jahr 2008 neu beschriebene Art, die in Thailand humane viszerale Leishmaniose verursacht. Die phylogenetischen Analysen zeigten die Ähnlichkeit von L. siamensis mit weiteren bisher nicht identifizierten Stämmen aus Martinique und Ghana, die kutane Leishmaniose bei Menschen verursachen. Um die Frage zu beantworten, ob sich die Leishmaniose zu einer in Mitteleuropa endemischen zoonotischen Krankheit entwickeln könnte, müssen weitere Studien über kompatible Vektoren, mögliche Reservoire und zur Virulenz durchgeführt werden

Smart Retail in Smart Cities: Best Practice Analysis of Local Online Platforms

Against the background of urban transformation processes aggravated by e-commerce, this paper discusses chances and challenges of local online platforms. Three hypotheses are introduced. Firstly, the rapid emergence of numerous local online platforms in various European countries is linked to the urban heritage of the European City. Secondly, the success of these platforms depends on the integration of diverse services. Thirdly it is argued, that platforms need to adapt to future topics of smart retail which is why a more holistic approach is appropriate. A best practice analysis is conducted, which gives an insight into the variety and complexity of local online platforms

DipA, a pore-forming protein in the outer membrane of lyme disease spirochetes exhibits specificity for the permeation of dicarboxylate

Lyme disease Borreliae are highly dependent on the uptake of nutrients provided by their hosts. Our study describes the identification of a 36 kDa protein that functions as putative dicarboxylate-specific porin in the outer membrane of Lyme disease Borrelia. The protein was purified by hydroxyapatite chromatography from Borrelia burgdorferi B31 and designated as DipA, for dicarboxylate-specific porin A. DipA was partially sequenced, and corresponding genes were identified in the genomes of B. burgdorferi B31, Borrelia garinii PBi and Borrelia afzelii PKo. DipA exhibits high homology to the Oms38 porins of relapsing fever Borreliae. B. burgdorferi DipA was characterized using the black lipid bilayer assay. The protein has a singlechannel conductance of 50 pS in 1 M KCl, is slightly selective for anions with a permeability ratio for cations over anions of 0.57 in KCl and is not voltage-dependent. The channel could be partly blocked by different di- and tricarboxylic anions. Particular high stability constants up to about 28,000 l/mol (in 0.1 M KCl) were obtained among the 11 tested anions for oxaloacetate, 2-oxoglutarate and citrate. The results imply that DipA forms a porin specific for dicarboxylates which may play an important role for the uptake of specific nutrients in different Borrelia species

Metabolic shift towards increased biohydrogen production during dark fermentation in the anaerobic fungus Neocallimastix cameroonii G341

Background Anaerobic fungi of the phylum Neocallimastigomycota have a high biotechnological potential due to their robust lignocellulose degrading capabilities and the production of several valuable metabolites like hydrogen, acetate, formate, lactate, and ethanol. The metabolism of these fungi, however, remains poorly understood due to limitations of the current cultivation strategies in still-standing bottles, thereby restricting the comprehensive evaluation of cultivation conditions. Results We describe the analysis of growth conditions and their influence on the metabolism of the previously isolated fungus Neocallimastix cameroonii G341. We established a bioreactor process in a stirred tank, enabling cultivation under defined conditions. The optimal growth temperature for the fungus was between 38.5 °C and 41.5 °C, while the optimal pH was 6.6–6.8. Like other dark fermentation systems, hydrogen production is dependent on the hydrogen partial pressure and pH. Shaking the bottles or stirring the fermenters led to an increase in hydrogen and a decrease in lactate and ethanol production. Regulation of the pH to 6.8 in the fermenter nearly doubled the amount of produced hydrogen. Conclusions Novel insights into the metabolism of Neocallimastix cameroonii were gained, with hydrogen being the preferred way of electron disposal over lactate and ethanol. In addition, our study highlights the potential application of the fungus for hydrogen production from un-pretreated biomass. Finally, we established the first cultivation of an anaerobic fungus in a stirred tank reactor system