Efeitos do exercício de tronco na recuperação funcional da marcha em pacientes pós acidente vascular cerebral: uma revisão sistemática

Introdução: o acidente vascular cerebral (AVC), acarreta deficiências que variam em função da topografia, tipo e extensão da lesão, mas na maioria das vezes apresentam alterações cognitivas, motoras, sensoriais e autonômicas variadas. Entre essas alterações, a força de tronco reduzida após o AVC aumenta o trabalho mecânico para a marcha, repercutindo na capacidade funcional do paciente. Objetivo: investigar quais as técnicas mais utilizadas para o fortalecimento de tronco. Método: foram realizadas buscas nas bases de dados: Pubmed, Bireme, Scielo e PEDro. Foram incluídos estudos clínicos randomizados e controlados que compararam os efeitos do fortalecimento de tronco na marcha em pacientes acometidos pelo AVC. Resultados: dos 109 estudos encontrados, 10 foram selecionados e avaliados pela escala PEDro, e apresentaram boa qualidade metodológica. A intervenção mais encontrada foram os exercícios de estabilidade dos musculos mais profundas do tronco e da pelve. Conclusão: os exercícios de tronco influenciam de forma positiva aspectos importantes da marcha

Electrochemical and mechanical behavior of UV curing paint on hybrid films modified with polyethyleneglycol plasticizer applied on tinplate

The objective of this work is to coat tinplate with a hybrid film obtained from a sol-gel process constituted by the alkoxide precursor tetraethoxysilane (TEOS) and 3-trimethoxysilylpropyl methacrylate (TMSM), with the addition of cerium nitrate (0.01 M) and polyethyleneglycol plasticizer (20 g.L-1) to the sol formulation. The films were obtained by dip-coating, applying one and two layers and curing them at different temperatures (60°C and 90°C) for 20 minutes, and adhering UV curing paint to each film respectively. The results showed that the double layered hybrid film obtained at 60°C had a higher layer of thickness and the best performance in the electrochemical assays, in other words, higher resistance to corrosion. Furthermore, in studies following the application of UV coating, the hybrid-film monolayer cured at 60°C wich had an organic coating of cured UV applied to it, achieved a performance similar to that of the pretreated alkyd greenhouse currently used in the metal packaging industry

Post-Transplant Nivolumab Plus Unselected Autologous Lymphocytes in Refractory Hodgkin Lymphoma: A Feasible and Promising Salvage Therapy Associated With Expansion and Maturation of NK Cells

Immune checkpoint inhibitors (CI) have demonstrated clinical activity in Hodgkin Lymphoma (HL) patients relapsing after autologous stem cell transplantation (ASCT), although only 20% complete response (CR) rate was observed. The efficacy of CI is strictly related to the host immune competence, which is impaired in heavily pre-treated HL patients. Here, we aimed to enhance the activity of early post-ASCT CI (nivolumab) administration with the infusion of autologous lymphocytes (ALI). Twelve patients with relapse/refractory (R/R) HL (median age 28.5 years; range 18-65), underwent lymphocyte apheresis after first line chemotherapy and then proceeded to salvage therapy. Subsequently, 9 patients with progressive disease at ASCT received early post-transplant CI supported with four ALI, whereas 3 responding patients received ALI alone, as a control cohort. No severe adverse events were recorded. HL-treated patients achieved negative PET scan CR and 8 are alive and disease-free after a median follow-up of 28 months. Four patients underwent subsequent allogeneic SCT. Phenotypic analysis of circulating cells showed a faster expansion of highly differentiated NK cells in ALI plus nivolumab-treated patients as compared to control patients. Our data show anti-tumor activity with good tolerability of ALI + CI for R/R HL and suggest that this setting may accelerate NK cell development/maturation and favor the expansion of the "adaptive" NK cell compartment in patients with HCMV seropositivity, in the absence of HCMV reactivation

MAMMALS IN PORTUGAL : A data set of terrestrial, volant, and marine mammal occurrences in P ortugal

Mammals are threatened worldwide, with 26% of all species being includedin the IUCN threatened categories. This overall pattern is primarily associatedwith habitat loss or degradation, and human persecution for terrestrial mam-mals, and pollution, open net fishing, climate change, and prey depletion formarine mammals. Mammals play a key role in maintaining ecosystems func-tionality and resilience, and therefore information on their distribution is cru-cial to delineate and support conservation actions. MAMMALS INPORTUGAL is a publicly available data set compiling unpublishedgeoreferenced occurrence records of 92 terrestrial, volant, and marine mam-mals in mainland Portugal and archipelagos of the Azores and Madeira thatincludes 105,026 data entries between 1873 and 2021 (72% of the data occur-ring in 2000 and 2021). The methods used to collect the data were: live obser-vations/captures (43%), sign surveys (35%), camera trapping (16%),bioacoustics surveys (4%) and radiotracking, and inquiries that represent lessthan 1% of the records. The data set includes 13 types of records: (1) burrowsjsoil moundsjtunnel, (2) capture, (3) colony, (4) dead animaljhairjskullsjjaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8),observation in shelters, (9) photo trappingjvideo, (10) predators dietjpelletsjpine cones/nuts, (11) scatjtrackjditch, (12) telemetry and (13) vocalizationjecholocation. The spatial uncertainty of most records ranges between 0 and100 m (76%). Rodentia (n=31,573) has the highest number of records followedby Chiroptera (n=18,857), Carnivora (n=18,594), Lagomorpha (n=17,496),Cetartiodactyla (n=11,568) and Eulipotyphla (n=7008). The data setincludes records of species classified by the IUCN as threatened(e.g.,Oryctolagus cuniculus[n=12,159],Monachus monachus[n=1,512],andLynx pardinus[n=197]). We believe that this data set may stimulate thepublication of other European countries data sets that would certainly contrib-ute to ecology and conservation-related research, and therefore assisting onthe development of more accurate and tailored conservation managementstrategies for each species. There are no copyright restrictions; please cite thisdata paper when the data are used in publications.info:eu-repo/semantics/publishedVersio

Mammals in Portugal: a data set of terrestrial, volant, and marine mammal occurrences in Portugal

Mammals are threatened worldwide, with ~26% of all species being included in the IUCN threatened categories. This overall pattern is primarily associated with habitat loss or degradation, and human persecution for terrestrial mammals, and pollution, open net fishing, climate change, and prey depletion for marine mammals. Mammals play a key role in maintaining ecosystems functionality and resilience, and therefore information on their distribution is crucial to delineate and support conservation actions. MAMMALS IN PORTUGAL is a publicly available data set compiling unpublished georeferenced occurrence records of 92 terrestrial, volant, and marine mammals in mainland Portugal and archipelagos of the Azores and Madeira that includes 105,026 data entries between 1873 and 2021 (72% of the data occurring in 2000 and 2021). The methods used to collect the data were: live observations/captures (43%), sign surveys (35%), camera trapping (16%), bioacoustics surveys (4%) and radiotracking, and inquiries that represent less than 1% of the records. The data set includes 13 types of records: (1) burrows | soil mounds | tunnel, (2) capture, (3) colony, (4) dead animal | hair | skulls | jaws, (5) genetic confirmation, (6) inquiries, (7) observation of live animal (8), observation in shelters, (9) photo trapping | video, (10) predators diet | pellets | pine cones/nuts, (11) scat | track | ditch, (12) telemetry and (13) vocalization | echolocation. The spatial uncertainty of most records ranges between 0 and 100 m (76%). Rodentia (n =31,573) has the highest number of records followed by Chiroptera (n = 18,857), Carnivora (n = 18,594), Lagomorpha (n = 17,496), Cetartiodactyla (n = 11,568) and Eulipotyphla (n = 7008). The data set includes records of species classified by the IUCN as threatened (e.g., Oryctolagus cuniculus [n = 12,159], Monachus monachus [n = 1,512], and Lynx pardinus [n = 197]). We believe that this data set may stimulate the publication of other European countries data sets that would certainly contribute to ecology and conservation-related research, and therefore assisting on the development of more accurate and tailored conservation management strategies for each species. There are no copyright restrictions; please cite this data paper when the data are used in publications

Comportamento eletroquímico e mecânico do alumínio aa2024-t3 revestido com filme híbrido contendo óxido de grafeno

The aeronautics industry uses aluminum alloy AA2024-T3 due to its low density and good mechanical properties. However, this alloy requires the use of protective coatings because it does not have the corrosion and wear resistance required by the aeronautics industry. In this context, this work aims at evaluating the performanceof AA2024-T3 aluminum coated with hybrid films containing graphene oxide. The hybrid films were obtained by a dip coating process from a sol composed by tetraethoxysilane/3 (trimethoxysilylpropyl) methacrylate/cerium nitrate/ethanol/water with different concentrations of graphene oxide in suspension. The morphology was evaluated by Scanning Electron Microscopy. The corrosion resistance and wear behavior of the obtained coatings were characterized by open circuit potential, polarization curves and dry wear tests using constant force in a ball-on-plate tribometer. In the studied conditions, the metal coated with hybrid matrix films containing graphene oxide presented no changes in the corrosion resistance, but it showed a positive contribution to the wear resistance.A indústria aeronáutica utiliza a liga de alumínio AA2024-T3 devido a sua baixa densidade e boas propriedades mecânicas. Contudo, essa liga requer o uso de revestimentos protetores, pois não tem a resistência a corrosão e ao desgaste necessário para esta aplicação. Nesse contexto, este trabalho visa avaliar o desempenho da liga de alumínio AA2024-T3 revestida com filmes híbridos contendo óxido de grafeno. Os filmes híbridos são obtidos por processo de dip coating de um sol composto por tetraetoxisilano/3 (trimetoxisilylpropil) metacrilatonitrato de cério/etanol/água com diferentes concentrações de óxido de grafeno em suspensão. A morfologia foi avaliada por Microscopia Eletrônica de Varredura. O comportamento em relação a resistência à corrosão e ao desgaste dos revestimentos foi avaliada por potencial de circuito aberto, curvas de polarização e testes de desgaste a seco com força constante em um tribômetro ball-on-plate. Nas condições estudadas, o metal revestido com filmes híbridos contendo óxido de grafeno não apresentou mudanças na resistência a corrosão, mas mostrou uma contribuição positiva na resistência a abrasão