Virtual and rapid prototyping of an underactuated space end effector

A fast and reliable verification of an initial concept is an important need in the field of mechatronics. Usually, the steps for a successful design require multiple iterations involving a sequence of design phases-the initial one and several improvements-and the tests of the resulting prototypes, in a trial and error scheme. Now a day’s software and hardware tools allow for a faster approach, in which the iterations between design and prototyping are by far reduced, even to just one in favorable situation. This work presents the design, manufacturing and testing of a robotic end effector for space applications, realized through virtual prototyping, followed by rapid prototyping realization. The first process allows realizing a mathematical model of the robotic system that, once all the simulations confirm the effectiveness of the design, can be directly used for the rapid prototyping by means of 3D printing. The workflow and the results of the process are described in detail in this paper, showing the qualitative and quantitative evaluation of the performance of both the virtual end effector and the actual physical robotic hand

Thermal simulations for optical transition radiation screen for Eli-NP compton gamma source

The ELI-NP GBS (Extreme Light Infrastructure-Nuclear Physics Gamma Beam Source) is a high brightness elec-tron LINAC that is being built in Romania. The goal for this facility is to provide high luminosity gamma beam through Compton Backscattering. A train of 32 bunches at 100Hz with a nominal charge of 250pC is accelerated up to 740 MeV. Two interaction points with an IR Laser beam produces the gamma beam at different energies. In order to measure the electron beam spot size and the beam proper-ties along the train, the OTR screens must sustain the ther-mal and mechanical stress due to the energy deposited by the bunches. This paper is an ANSYS study of the issues due to the high quantity of energy transferred to the OTR screen. They will be shown different analysis, steady-state and thermal transient analysis, where the input loads will be the internal heat generation equivalent to the average power, deposited by the ELI-GBS beam in 512 ns, that is the train duration. Each analyses will be followed by the structural analysis to investigate the performance of the OTR materi

Spot size measurements in the Eli-NP compton gamma source

A high brightness electron Linac is being built in the Compton Gamma Source at the ELI Nuclear Physics facility in Romania. To achieve the design luminosity, a train of 32 bunches with a nominal charge of 250 pC and 16 ns spacing , will collide with the laser beam in the interaction point. Electron beam spot size is measured with an OTR (optical transition radiation) profile moni-tors. In order to measure the beam properties, the optical radiation detecting system must have the necessary accu-racy and resolution. This paper deals with the studies of different optic configurations to achieve the magnifica-tion, resolution and accuracy desired considering design and technological constraints; we will compare several configurations of the optical detection line to justify the one chosen for the implementation in the Lina

Longitudinal and Transverse Wakefields Simulations and Studies in Dielectric-Coated Circular Waveguides

In recent years, there has been a growing interest and rapid experimental progress on the use of e.m. fields produced by electron beams passing through dielectric-lined structures and on the effects they might have on the drive and witness bunches. Short ultra-relativistic electron bunches can excite very intense wakefields, which provide an efficient acceleration through the dielectric wakefield accelerators (DWA) scheme with higher gradient than that in the conventional RF LINAC. These beams can also generate high power narrow band THz coherent Cherenkov radiation. These high gradient fields may create strong instabilities on the beam itself causing issues in plasma acceleration experiments (PWFA), plasma lensing experiments and in recent beam diagnostic applications. In this work we report the results of the simulations and studies of the wakefields generated by electron beams at different lengths and charges passing on and off axis in dielectric-coated circular waveguides. We also propose a semi-analytical method to calculate these high gradient fields without resorting to time consuming simulations

Separase prevents genomic instability by controlling replication fork speed

Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development. Sister chromatid separation is triggered by Separase, an evolutionary conserved protease that cleaves the cohesin complex, allowing the dissolution of sister chromatid cohesion. Here we provide evidence that Separase participates in genomic stability maintenance by controlling replication fork speed. We found that Separase interacted with the replication licensing factors MCM2-7, and genome-wide data showed that Separase co-localized with MCM complex and cohesin. Unexpectedly, the depletion of Separase increased the fork velocity about 1.5-fold and caused a strong acetylation of cohesin's SMC3 subunit and altered checkpoint response. Notably, Separase silencing triggered genomic instability in both HeLa and human primary fibroblast cells. Our results show a novel mechanism for fork progression mediated by Separase and thus the basis for genomic instability associated with tumorigenesis

Separase prevents genomic instability by controlling replication fork speed

Proper chromosome segregation is crucial for preserving genomic integrity, and errors in this process cause chromosome mis-segregation, which may contribute to cancer development. Sister chromatid separation is triggered by Separase, an evolutionary conserved protease that cleaves the cohesin complex, allowing the dissolution of sister chromatid cohesion. Here we provide evidence that Separase participates in genomic stability maintenance by controlling replication fork speed. We found that Separase interacted with the replication licensing factors MCM2-7, and genome-wide data showed that Separase co-localized with MCM complex and cohesin. Unexpectedly, the depletion of Separase increased the fork velocity about 1.5-fold and caused a strong acetylation of cohesin's SMC3 subunit and altered checkpoint response. Notably, Separase silencing triggered genomic instability in both HeLa and human primary fibroblast cells. Our results show a novel mechanism for fork progression mediated by Separase and thus the basis for genomic instability associated with tumorigenesis

Optical issues for the diagnostic stations for the ELI-NP compton gamma source

A high brightness electron Linac is being built in the Compton Gamma Source at the ELI Nuclear Physics facility in Romania. To achieve the design luminosity, a train of 32 bunches, 16 ns spaced, with a nominal charge of 250 pC will collide with the laser beam in the interaction point. Electron beam spot size is measured with optical transition radiation (OTR) profile monitors. In order to measure the beam properties, the optical radiation detecting system must have the necessary accuracy and resolution. This paper deals with the studies of different optic configurations to achieve the magnification, resolution and accuracy in order to measure very small beam (below 30 μm) or to study the angular distribution of the OTR and therefore the energy of the beam. Several configurations of the optical detection line will be studied both with simulation tools (e.g. Zemax) and experimentally. The paper will deal also with the sensibility of optic system (in terms of depth of field, magnification and resolution) to systematic error

Re-active Passive (RAP) Devices for Control of Noise Transmission through a Panel

Re-Active Passive (RAP) devices have been developed to control low frequency (200 Hz), reactive distributed vibration absorber) to cover the medium frequency range (75 to 250 Hz), and active control for controlling low frequencies (<200 Hz). The device was applied to control noise transmission through a panel mounted in a transmission loss test facility. Experimental results are presented for the bare panel, and combinations of passive treatment, reactive treatment, and active control. Results indicate that three RAP devices were able to increase the overall broadband (15-1000 Hz) transmission loss by 9.4 dB. These three devices added a total of 285 grams to the panel mass of 6.0 kg, or approximately 5%, not including control electronics

Design of high gradient, high repetition rate damped C-band rf structures

The gamma beam system of the European Extreme Light Infrastructure–Nuclear Physics project foresees the use of a multibunch train colliding with a high intensity recirculated laser pulse. The linac energy booster is composed of 12 traveling wave C-band structures, 1.8 m long with a field phase advance per cell of 2π=3 and a repetition rate of 100 Hz. Because of the multibunch operation, the structures have been designed with a dipole higher order mode (HOM) damping system to avoid beam breakup (BBU). They are quasiconstant gradient structures with symmetric input couplers and a very effective damping of the HOMs in each cell based on silicon carbide (SiC) rf absorbers coupled to each cell through waveguides. An optimization of the electromagnetic and mechanical design has been done to simplify the fabrication and to reduce the cost of the structures. In the paper, after a review of the beam dynamics issues related to the BBU effects, we discuss the electromagnetic and thermomechanic design criteria of the structures. We also illustrate the criteria to compensate the beam loading and the rf measurements that show the effectiveness of the HOM damping