Pyroclastic lumps: quick diapiric structures off the Naples Bay, Italy. European Geophysical Society (EGS), 25th General Assembly, Millenium Conference on Earth, Planetary & Solar Systems. Nice (France) 25-29 Aprii 2000.

Sacchi M., D'Argenio B., Morra V., Petrazzuoli S., Àiello G., Budillon F., Samacchiaro G. and Tonielli R., 2000. Pyroclastic lumps: quick diapiric structures off the Naples Bay, Italy. European Geophysical Society (EGS), 25th General Assembly, Millenium Conference on Earth, Planetary & Solar Systems. Nice (France) 25-29 Aprii 2000

The Gravitational Pull Hypothesis and imperfective/perfective aspect in Catalan translation

[EN] This article aims to test the Gravitational Pull Hypothesis on the imperfective/perfective aspect distinction in the language pairs English-Catalan and French-Catalan. It draws on the corresponding corpora in COVALT. The GPH posits three cognitive causes of translational effects: source or target language salience and connectivity. Different configurations of these causes, or factors, are expected to result in over- or under-representation of target language features. The imperfective/perfective aspect distinction was chosen as a testing ground for the GPH because it is morphologically marked in Catalan and French but not in English. That may give rise to different configurations of factors and, therefore, to different translational effects. It is predicted that the preterite, which conveys perfective aspect in Catalan, will be over-represented in Catalan translations from English as compared to translations from French and to Catalan non-translations. On the other hand, the imperfect, which conveys imperfective aspect, will be under-represented. Results confirm these predictions. For translations from French, both adherence to the patterns observed in Catalan non-translations and over-representation of the preterite are possible outcomes. Results lend support to the second alternative & horbar; over-representation of the preterite. These results highlight the importance of relying on frequency and other sources of evidence when formulating hypotheses in the framework of the GPH. Research from the field of second language acquisition proved particularly significant in this respect.PID2019-103953GB-I00 funded by MCIN/AEI/ 10.13039/501100011033.Marco Borillo, J.; Peña-Martinez, G. (2023). The Gravitational Pull Hypothesis and imperfective/perfective aspect in Catalan translation. Languages in Contrast. 23(2):226-251. https://doi.org/10.1075/lic.00030.bor22625123

Recovery of a medieval Brucella melitensis genome using shotgun metagenomics

Shotgun metagenomics provides a powerful assumption-free approach to the recovery of pathogen genomes from contemporary and historical material. We sequenced the metagenome of a calcified nodule from the skeleton of a 14th-century middle-aged male excavated from the medieval Sardinian settlement of Geridu. We obtained 6.5-fold coverage of a Brucella melitensis genome. Sequence reads from this genome showed signatures typical of ancient or aged DNA. Despite the relatively low coverage, we were able to use information from single-nucleotide polymorphisms to place the medieval pathogen genome within a clade of B. melitensis strains that included the well-studied Ether strain and two other recent Italian isolates. We confirmed this placement using information from deletions and IS711 insertions. We conclude that metagenomics stands ready to document past and present infections, shedding light on the emergence, evolution, and spread of microbial pathogens

A Much Sought-After Drug—Propofol Sedation for GI Endoscopy: Always Better but Who Cares?

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Annotation and representation of a diachronic corpus of Spanish

In this article we describe two different strategies for the automatic tagging of a Spanish diachronic corpus involving the adaptation of existing NLP tools developed for modern Spanish. In the initial approach we follow a state-of-the-art strategy, which consists on standardizing the spelling and the lexicon. This approach boosts POS-tagging accuracy to 90, which represents a raw improvement of over 20% with respect to the results obtained without any pre-processing. In order to enable non-expert users in NLP to use this new resource, the corpus has been integrated into IAC (Corpora Interface Access). We discuss the shortcomings of the initial approach and propose a new one, which does not consist in adapting the source texts to the tagger, but rather in modifying the tagger for the direct treatment of the old variants.This second strategy addresses some important shortcomings in the previous approach and is likely to be useful not only in the creation of diachronic linguistic resources but also for the treatment of dialectal or non-standard variants of synchronic languages as well.Peer ReviewedPostprint (published version

Recent advances steer the future of systemic sclerosis toward precision medicine

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Dynamic markers based on blood perfusion fluctuations for selecting skin melanocytic lesions for biopsy

Skin malignant melanoma is a highly angiogenic cancer, necessitating early diagnosis for positive prognosis. The current diagnostic standard of biopsy and histological examination inevitably leads to many unnecessary invasive excisions. Here, we propose a non-invasive method of identification of melanoma based on blood flow dynamics. We consider a wide frequency range from 0.005 – 2 Hz associated with both local vascular regulation and effects of cardiac pulsation. Combining uniquely the power of oscillations associated with individual physiological processes we obtain a marker which distinguishes between melanoma and atypical nevi with sensitivity of 100% and specificity of 90.9%. The method reveals valuable functional information about the melanoma microenvironment. It also provides the means for simple, accurate, in vivo distinction between malignant melanoma and atypical nevi, and may lead to a substantial reduction in the number of biopsies currently undertaken

Clinical characterization of a 6-year-old patient with autism and two adjacent duplications on 10q11.22q11.23. a case report

Autism is a neurodevelopmental disorder presenting in the first 3 years of life. Deficits occur in the core areas of social communication and interaction and restricted, repetitive patterns of behavior, interests or activities. The causes of autism are unknown, but clinical genetic studies show strong evidence in favor of the involvement of genetic factors in etiology. Molecular genetic studies report some associations with candidate genes, and candidate regions have emerged from several genome-wide linkage studies. Here, we report a clinical case of autism in a 6-year-old boy with double duplication on 10q11.22q11.23 with ASD (Autism Spectrum Disorder), intellectual disability, developmental delay, hypotonia, gross-motor skills deficit, overgrowth and mild dysmorphic features. In the literature, only five cases of ASD with 10q11.21q11.23 duplication are reported. This is the first extensive clinical description of an ASD subject with 10q11.22q11.23 duplication. Our findings suggest that 10q11.21q11.23 microduplication could represent a copy number variant that predisposes to autism

Effect of organic and mineral fertilizers on greenhouse gases emissions from an irrigated maize crop in Madrid Spain

Both solid or liquid OF showed a significant abatement of N2O cumulative emissions in this irrigated Mediterranean cropping area (P < 0.05) comparing to U. Urea-Pig Compost (U-PC) treatment showed the lowest CH4 sink and highest cumulative soil respiration rates (P<05). Considering GHG-GWP, the use of OF can be considered as an advisable practice to mitigate GHG emissions under Mediterranean climatic conditions