Of false philosophers and inept teachers: Theodore Prodromos’ satirical writings (with a translation of the poem Against the old man with a long beard).

Ψευδοφιλόσοφοι και Αδαείς Δάσκαλοι: Τα σατιρικά κείμενα του Θεοδώρου ΠροδρόμουΟρισμένα από τα σατιρικά κείμενα του Θεοδώρου Προδρόμου (όπως ο Φιλοπλάτων, ο Αμαθής, ή το ποίημα κατά μακρογενείου γέροντος) μπορούν να θεωρηθούν ως οι διδακτικές του προγραμματικές δηλώσεις. Επιπλέον δείχνουν πώς αντιλαμβανόταν ο Πρόδρομος την «ὑπόκρισιν», να προσποιείται δηλαδή κάποιος ότι είναι ένας άλλος

Assessment Practices in Residential Treatment Facilities for Juvenile Offenders

Given the high prevalence of mental disorders among juvenile offenders, as well as the link between untreated disorders and delinquent behavior, there is a critical need for standardized, cost-effective, and clinically effective procedures to identify youth with mental health problems. Surveys were sent to staff in juvenile residential facilities throughout Pennsylvania to examine statewide assessment practices, including the background and training of staff, the standard intake procedures used in these facilities, and the role of assessment in treatment planning. Although results provide evidence of some common statewide assess-ment practices, there was significant variability in the use of specific procedures. Suggestions are offered for enhancing mental health screening and assessment in juvenile justice facilities

Ambulatory Thoracoscopic Pleurodesis Combined With Indwelling Pleural Catheter in Malignant Pleural Effusion.

Background and Objective: Malignant pleural effusion (MPE) often results in debilitating symptoms. Relief of dyspnoea and improvement in quality of life can be achieved with either talc pleurodesis or insertion of an indwelling tunneled pleural catheter (IPC). The former requires a lengthy hospital stay and the latter is associated with lower pleurodesis rates. In response to limited hospital bed capacity, we developed a pragmatic approach in managing MPE by combining thoracoscopic talc poudrage and insertion of IPC into a single day case procedure. We present data on the safety and efficacy of this approach. Methods: Patients who had undergone the abovementioned procedure between 2017 and 2020 were analyzed. Demographic data, hospital length of stay (LOS), histological diagnosis, rates of pleurodesis success and procedural related complications were collated. Patients were followed-up for 6 months. Results: Forty-five patients underwent the procedure. Mean age was 68.5 ± 10.4 years and 56% were male. Histological diagnosis was achieved in all cases. 86.7% of patients were discharged on the day of the procedure. Median LOS was 0 (IQR 0-0) days. Successful pleurodesis was attained in 77.8% at 6-month follow-up. No procedure related deaths or IPC related infections were recorded. Conclusion: Ambulatory thoracoscopic poudrage and IPC insertion is a safe and effective option in the management of MPE. All patients received a definitive pleural intervention with 77.8% pleurodesis success at 6-months and majority of them discharged on the same day. Future randomized trials are required to confirm these findings

A model for stem cell population dynamics with regulated maturation delay

We develop a structured population model for the maturation process of stem cells in the form of a state-dependent delay differential equation. Moreover, results on existence, uniqueness and positivity of solutions as well as conditions of existence for equilibria and representations of these are established. We give biological interpretations for the conditions of existence of equilibria

Stability analysis of multi-compartment models for cell production systems

We study two-and three-compartment models of a hierarchical cell production system with cell division regulated by the level of mature cells. We investigate the structure of equilibria with respect to parameters as well as local stability properties for the equilibria. To interpret the results we adapt the concept of reproduction numbers, which is well known in ecology, to stem cell population dynamics. In the two-compartment model, the positive equilibrium is stable wherever it exists. In the three-compartment model, we find that the intermediate stage of differentiation is responsible for the emergence of an instability region in the parameter plane. Moreover, we prove that this region shrinks as the mortality rate for mature cells increases and discuss this result

Stawanie si\u119 nauczycielem akademickim: analiza symboliczno-interakcjonistyczna

Klasyfikacja tematyczna: Psychologia osobowo\u15bci; Psychologia spo\u142eczna; Psychologia wychowawcza; Socjologia o\u15bwiaty i wychowania; Metodologia i metody bada\u144 socjologicznych; Andragogika. O\u15bwiata doros\u142yc

The integrated stress response in lung disease.

Lungs are repeatedly exposed to inhaled toxic insults, such as smoke, diesel exhaust, and microbes, which elicit cellular stress responses. The phosphorylation of eukaryotic translation initiation factor 2α by one of four stress-sensing kinases triggers a pathway called the integrated stress response that helps protect cellular reserves of nutrients and prevents the accumulation of toxic proteins. In this review, we discuss how activation of the integrated stress response has been shown to play an important role in pulmonary pathology, and how its study may help in the development of novel therapies for diverse conditions, from hypoxia to cancer