368 research outputs found

    Novos Paradigmas de Direitos Sociais e a Dignidade da Pessoa Humana, Analisada Sob o Enfoque do Direito de Personalidade do Trabalhador em um Mundo Globalizado

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    New paradigms of social rights in relation to human dignity will be analyzed, principally in situations in which workers are morally degraded because of globalization, by virtue of its ready generation of unemployment. First, the distinction (or lack thereof) will be examined with respect to social rights in relation to other rights. The question of globalization will also be considered, emphasizing the economic crisis as a factor that directly and indirectly produces problems everywhere.  The primary objective will be to point to a solution to such a troubling situation. The methodology used will be bibliographic research and analysis of legislation.    Analisar-se-ão novos paradigmas de Direitos Sociais em relação à dignidade da pessoa humana, principalmente na situação em que o trabalhador é aviltado em sua moral em razão da globalização, que pode gerar facilmente desemprego. Primeiramente se fará uma diferenciação, ou não, dos Direitos Sociais em relação a outros Direitos. Abordar-se-á, também, a questão da globalização com a abordagem da crise econômica como fator que gera problemas diretos e indiretos em todo o mundo. O objetivo principal será apontar a saída para tal situação preocupante. A metodologia empregada será a de pesquisa bibliográfica e estudo da legislação

    A modernização do território goiano e a construção de (Re)Existências

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     ResumoO presente artigo objetiva refletir sobre o processo de modernização da agricultura goiana, que a partir da mobilidade do capital e do trabalho e seguindo a lógica de reprodução e hegemonia do capital nacional e internacional, foi moldando diferentes formas de apropriação territorial e de arranjos produtivos que perpassaram/perpassam a mineração, a pecuária e a agricultura. Esse processo carrega consigo inúmeras contradições, produzindo desigualdades espaciais, expropriação territorial, mercantilização dos espaços de produção e vida, além de inúmeros conflitos socioespaciais. São dessas contradições e conflitos que vemos emergir (Re)Existências como contribuições para a construção de um outro modelo de desenvolvimento que prime pelo bem viver, produzindo e sendo reproduzidas cotidianamente por sujeitos camponeses, quilombolas, indígenas, etc., que no dia a dia e na prática reescrevem o território na perspectiva de uma vida mais digna.Palavras-chave: Território; (Re)existências; Mobilidade do Capital e do Trabalho. AbstractThe present article aims to reflect on the process of modernization of agriculture in the state of Goiás, which, based on the mobility of capital and labor and following the logic of reproduction and hegemony of national and international capital, has shaped different forms of territorial appropriation and productive arrangements that through mining, cattle raising and agriculture. This process carries with it numerous contradictions, producing spatial inequalities, territorial expropriation, commercialization of production and life spaces, and innumerable socio-spatial conflicts. It is these contradictions and conflicts that we see emerge (Re) Existences as contributions to the construction of another model of development that prevails for the good to live, producing and being reproduced daily by peasants, quilombolas, indigenous people, etc., that day by day and in practice rewrite the territory in the perspective of a more dignified life.Key-words: Territory, (Re) Existences; Labor and Capital Mobility

    Testosterone deficiency increases hospital readmission and mortality rates in male patients with heart failure.

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    BackgroundTestosterone deficiency in patients with heart failure (HF) is associated with decreased exercise capacity and mortality; however, its impact on hospital readmission rate is uncertain. Furthermore, the relationship between testosterone deficiency and sympathetic activation is unknown.ObjectiveWe investigated the role of testosterone level on hospital readmission and mortality rates as well as sympathetic nerve activity in patients with HF.MethodsTotal testosterone (TT) and free testosterone (FT) were measured in 110 hospitalized male patients with a left ventricular ejection fraction < 45% and New York Heart Association classification IV. The patients were placed into low testosterone (LT; n = 66) and normal testosterone (NT; n = 44) groups. Hypogonadism was defined as TT < 300 ng/dL and FT < 131 pmol/L. Muscle sympathetic nerve activity (MSNA) was recorded by microneurography in a subpopulation of 27 patients.ResultsLength of hospital stay was longer in the LT group compared to in the NT group (37 ± 4 vs. 25 ± 4 days; p = 0.008). Similarly, the cumulative hazard of readmission within 1 year was greater in the LT group compared to in the NT group (44% vs. 22%, p = 0.001). In the single-predictor analysis, TT (hazard ratio [HR], 2.77; 95% confidence interval [CI], 1.58-4.85; p = 0.02) predicted hospital readmission within 90 days. In addition, TT (HR, 4.65; 95% CI, 2.67-8.10; p = 0.009) and readmission within 90 days (HR, 3.27; 95% CI, 1.23-8.69; p = 0.02) predicted increased mortality. Neurohumoral activation, as estimated by MSNA, was significantly higher in the LT group compared to in the NT group (65 ± 3 vs. 51 ± 4 bursts/100 heart beats; p < 0.001).ConclusionThese results support the concept that LT is an independent risk factor for hospital readmission within 90 days and increased mortality in patients with HF. Furthermore, increased MSNA was observed in patients with LT

    In vitro efficacy of latex and purified papain from Carica papaya against Strongyloides venezuelensis eggs and larvae

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    Latex from Carica papaya is rich in bioactive compounds, especially papain, which may help to control parasitic diseases. This study evaluated the efficacy of latex from C. papaya and purified papain against Strongyloides venezuelensis. The Egg Hatching Test (EHT) and the Larval Motility Test (LMT) using fresh and frozen latex (250mg/mL), lyophilized latex (34mg/mL), and purified papain (2.8 mg/mL) were performed. Albendazole (0.025 mg/mL) and ivermectin (316 ppm) were used as positive controls. EHT and LMT were carried out through the incubation of each solution with S. venezuelensis eggs or larvae (± 100 specimens), and results were analyzed after 48h (EHT) or 24, 48, and 72h (LMT). EHT showed that latex preparations at higher concentrations (1:10 to 1:100) resulted in partial or complete destruction of eggs and larvae inside the eggs. The result from the 1:1,000 dilution was similar to the positive control. LMT showed effectiveness in all the tested dilutions compared to negative controls. Purified papain showed a dose-dependent response in the EHT. Purified papain (2.8 mg/ mL) showed similar results to lyophilized latex at 1:1,000 in the EHT. Latex and purified papain from C. papaya were effective against S. venezuelensis eggs and larvae in vitro, suggesting their potential use as an alternative treatment for strongyloidiasis

    A Simple and Fast Method for the Production and Characterization of Methylic and Ethylic Biodiesels from Tucum Oil via an Alkaline Route

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    A simple, fast, and complete route for the production of methylic and ethylic biodiesel from tucum oil is described. Aliquots of the oil obtained directly from pressed tucum (pulp and almonds) were treated with potassium methoxide or ethoxide at 40°C for 40 min. The biodiesel form was removed from the reactor and washed with 0.1 M HCl aqueous solution. A simple distillation at 100°C was carried out in order to remove water and alcohol species from the biodiesel. The oxidative stability index was obtained for the tucum oil as well as the methylic and ethylic biodiesel at 6.13, 2.90, and 2.80 h, for storage times higher than 8 days. Quality control of the original oil and of the methylic and ethylic biodiesels, such as the amount of glycerin produced during the transesterification process, was accomplished by the TLC, GC-MS, and FT-IR techniques. The results obtained in this study indicate a potential biofuel production by simple treatment of tucum, an important Amazonian fruit

    The amygdala lesioning due to status epilepticus – Changes in mechanisms controlling chloride homeostasis

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    Objective: Amygdala has been demonstrated as one of the brain sites involved in the control of cardiorespiratory functioning. The structural and physiological alterations induced by epileptic activity are also present in the amygdala and reflect functional changes that may be directly associated with a sudden unexpected death. Seizures are always associated with neuronal damage and changes in the expression of cation-chloride cotransporters and Na/K pumps. In this study, the authors aimed to investigate if these changes are present in the amygdala after induction of status epilepticus with pilocarpine, which may be directly correlated with Sudden Unexpected Death in Epilepsy (SUDEP). Methods: Pilocarpine-treated wistar rats 60 days after Status Epilepticus (SE) were compared with control rats. Amygdala nuclei of brain slices immunostained for NKCC1, KCC2 and α1-Na+/K+-ATPase, were quantified by optical densitometry. Results: The amygdaloid complex of the animals submitted to SE had no significant difference in the NKCC1 immunoreactivity, but KCC2 immunoreactivity reduced drastically in the peri-somatic sites and in the dendritic-like processes. The α1-Na+/K+-ATPase peri-somatic immunoreactivity was intense in the rats submitted to pilocarpine SE when compared with control rats. The pilocarpine SE also promoted intense GFAP staining, specifically in the basolateral and baso-medial nuclei with astrogliosis and cellular debris deposition. Interpretation: The findings revealed that SE induces lesion changes in the expression of KCC2 and α1-Na+/K+-ATPase meaning intense change in the chloride regulation in the amygdaloid complex. These changes may contribute to cardiorespiratory dysfunction leading to SUDEP

    The Use of Internet and Social Networks as Methodological Tools in The School Environment

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    This work addresses the integration of the Internet and Social Networks to the teaching-learning processes in the school environment, using the computer as an intermediate tool between student and teacher. The use of these technologies is transforming human relationships in all their dimensions: economic, social, and educational. The cognitive development of these students is being mediated by these technological resources, where these new information and communication technologies will expand their potential. The objective of this study was to understand the importance of using the internet and social networks in the teaching-learning process in the school environment as a methodological resource and to what extent it is favorable to the student\u27s intellectual development

    Prospective study of a group of pre-university students evaluating anxiety and depression relationships with temporomandibular disorders

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    Objectives: The aim of this prospective longitudinal study was to evaluate the relationships between anxiety, depression, and temporomandibular disorders (TMD) in a sample of pre-university students submitted to a stressful event. Study design: 153 students from a pre-university course (82 females and 71 males between 16 and 31 years old) were given a survey about TMD symptoms and a survey about anxiety and depression scale at the beginning and the end of the preparatory course (August 2009-T1, and November 2009-T2). Results: Results were analyzed using a chi-square test and Odds Ratio (OR), significance level of á = 0.05. Statistical significance were found to depression rates in students with TMD (16% on T1 and 26% on T2, p = 0.001) as well as in general sample (12% on T1 and 22% on T2, p = 0.009), anxiety and TMD symptoms presented constant rates in both periods. Increased risk of having TMD were found in participants with anxiety (OR 2.6 in T2 and 5.6 in T1) and depression (2.0 in T2 and 3.3 in T1), but only anxiety reach statistical significance in both periods. Conclusions: TMD symptoms were a fluctuating variable that exchange between some individuals of this study. Independently of the TMD, depression rates significant increased in the evaluated period. Finally, anxiety was the psychological symptom related to the increased risk of having TMD
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