Las periferias urbanas de Galicia.

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Use of natural phenols as feed supplements with antioxidant effects on poultry products

The oxidation of lipids is the main cause of nutritional and organoleptic deterioration of bird´s meat and eggs. This process originates compounds responsible for unpleasant odours, reduces the amount of polyunsaturated fatty acids, vitamins and pigments, decreases the acceptability on consumers and generates compounds that may present toxicity. Dietary supplementation is a simple strategy to include compounds in animal tissues. Synthetic antioxidants are regularly supplemented in poultry. However, recently, it has increased the search for replacing those compounds for others of a natural origin. This work evaluates the potential use of natural phenols (main components of essential oils) as diet supplement antioxidant agents. Firstly, we evaluated the effects of thymol and carvacrol on the delay of oxidative deterioration in domestic chicken muscle samples storage at 4°C for 0, 5 and 10 days, and in comparison with BHT (a synthetic antioxidant compound massively used). The results show that supplementation with the 3 compounds were equally effective to delay the lipid oxidation of peroneus longus samples with no significant effects on pectoralis major. Quail diet supplementation with thymol or isoeugenol did not show significant changes in meat samples, however, the oxidation levels of fresh egg-yolk samples were affected. Isoeugenol showed a yolk antioxidant effect of similar magnitude than BHT suggesting a protective effect of that phenol during the formation of the oocyte. Thymol showed intermediate effects. Results suggest that the level of lipid oxidation protection is dependent on the species and the type and age of the product. Secondly, we assess the effects of thymol and isoeugenol supplementation on liver and egg yolk fatty acid composition. Thymol increased total unsaturated liver fatty acids compared to isoeugenol, BHT and control samples. Isoeugenol increased palmitoleic acid in yolk samples compared to BHT and controls, with thymol showing intermediate results. Interestingly, BHT samples, showed a non expected increased in the saturated/unsaturated ratio. The results suggest the usefulness of natural phenols to delay lipid oxidation. The findings may be considered relevant from a human nutritional and avian biology point of view because phenol supplementation could affect reproductive and embryonic development.Fil: Marín, Raúl Héctor. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales; Argentina.Fil: Marín, Raúl Héctor. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina.Fil: Luna, Agustín. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales; Argentina.Fil: Luna, Agustín. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina.Fil Lábaque, María C. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales; Argentina.Fil: Lábaque, María C. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina.Fil: Zygadlo, Julio A. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales; Argentina.Fil: Zygadlo, Julio A. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina.Otras Ciencias Veterinaria

Las prácticas didácticas en procesos de escolarización contemporáneos. Un estudio en dos escuelas secundarias públicas de la ciudad de Paraná.

Nuestro proyecto de investigación (PID 3156), de carácter exploratorio, indagó la conformación actual de las prácticas didácticas en dos escuelas públicas de la ciudad de Paraná. Con el supuesto de que dichas prácticas hoy asumen transformaciones sustantivas que exigen ser investigadas en terreno, éstas se abordaron en su positividad: tal y como son efectivamente producidas en específicas condiciones de emergencia (Foucault, 1997). Las aportes teórico-metodológicos de Foucault y de Bernstein señalaron nuestra perspectiva de análisis que buceó en: las condiciones escolares de emergencia de las prácticas didácticas, sus principios y códigos organizadores, su caracterización en las modalidades que asumen, las maneras en que las mismas se afianzan o se dispersan, en espacios de incertidumbre para dar lugar a nuevas, la permanencia de formas tradicionales junto al suceso de nuevos enmarcamientos didácticos que pujan por aparecer y lograr cierta estabilización. Espacio de producción de sujetos y de saberes donde se dan cita una serie de problemáticas contemporáneas en las que esta categoría de prácticas didácticas va definiendo su especificidad. Las producciones de este proyecto se consideran valiosos aportes para repensar los saberes del campo pedagógico-didáctico, la formación docente y los vínculos entre la Facultad de Ciencias de la Educación con instituciones de enseñanza secundaria de la ciudad de Paran

Basics of functional analysis with bicomplex scalars, and bicomplex Schur analysis

With the goal of providing the foundations for a rigorous study of modules of bicomplex holomorphic functions, we develop a general theory of functional analysis with bicomplex scalars. Even though the basic properties of bicomplex number are well known and widely available, our analysis requires some more delicate discussion of the various structures which are hidden in the ring of bicomplex numbers. We study in particular matrices with bicomplex numbers, bicomplex modules, and inner products and norms in bicomplex modules. We consider two kinds of norms on bicomplex modules: a real-valued norm (as one would expect), and a hyperbolic-valued norm. Interestingly enough, while both norms can be used to build the theory of normed bicomplex modules, the hyperbolic-valued norm appears to be much better compatible with the structure of bicomplex modules. We also consider linear functionals on bicomplex numbers. To conclude we describe a bicomplex version of classical Schur analysi

Lucía Raphael de la Madrid, Género y literatura. Hacia una perspectiva otra del derecho

Lucía Raphael de la Madrid, Género y literatura. Hacia una perspectiva otra del derecho(Ciudad de México, UNAM – INSTITUTO DE INVESTIGACIONES JURÍDICAS, 2015, 172 pp. ISBN 978-607-026-2388)di Ana María González Luna C

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

Acknowledgements: Authors want to express their gratitude to Dr. P. Davies (Albert Einstein College of Medicine, Bronx, NY, USA) and Lester I. Binder (NorthWestern, Chicago, IL, USA) for the generous gift of mAbs (TG-3, Alz-50, and MC1), and (TauC-3), respectively, and to M. en C. Ivan J. Galván-Mendoza for his support in confocal microscopy, and Ms. Maricarmen De Lorenz for her secretarial assistance. We also want to express our gratitude to the Mexican Families who donate the brain of their loved ones affected with Alzheimer's disease, and made possible our research. This work was financially supported by CONACyT grant, No. 142293 (For R.M).Peer reviewedPublisher PD

Simulating the efficacy of vaccines on the epidemiological dynamics of SARS-CoV-2 in a membrane computing model

This is a pre-copyedited, author-produced version of an article accepted for publication in [insert journal title] following peer review. The version of record [insert complete citation information here] is available online at: xxxxxxx [insert URL and DOI of the article on the OUP website].[EN] Membrane computing is a natural computing procedure inspired in the compartmental structure of living cells. This approach allows mimicking the complex structure of biological processes, and, when applied to transmissible diseases, can simulate a virtual `epidemic¿ based on interactions between elements within the computational model according to established conditions. General and focused vaccination strategies for controlling SARS-Cov-2 epidemics have been simulated for 2.3 years fromthe emergence of the epidemic in a hypothetical town of 10320 inhabitants in a country with mean European demographics where COVID-19 is imported. The age and immunological-response groups of the hosts and their lifestyles were minutely examined. The duration of natural, acquired immunity influenced the results; the shorter the duration, the more endemic the process, resulting in higher mortality, particularly among elderly individuals. During epidemic valleys between waves, the proportion of infected patients belonging to symptomatic groups (mostly elderly) increased in the total population, a population that largely benefits from standard double vaccination, particularly with boosters. There was no clear difference when comparing booster shots provided at 4 or 6 months after standard doubledose vaccination. Vaccines even of moderate efficacy (short-term protection) were effective in decreasing the number of symptomatic cases. Generalized vaccination of the entire population (all ages) added little benefit to overall mortality rates, and this situation also applied for generalized lockdowns. Elderly-only vaccination and lockdowns, even without general interventions directed to reduce population transmission, is sufficient for dramatically reducing mortality.This work was partially fund by the Fundación del Conocimiento Madri+d from the Madrid' Autonomous Community through a research contract (AVATAR-EPAMEC) within the Health Start Plus Program, promoted by the Carlos III Health Research Institute (ITEMAS), Ministry of Science, Innovation and Universities of Spain.Campos Frances, M.; Sempere Luna, JM.; Galán, JC.; Moya, A.; Cantón, R.; Llorens, C.; Baquero, F. (2022). Simulating the efficacy of vaccines on the epidemiological dynamics of SARS-CoV-2 in a membrane computing model. microLife. 3:1-13. https://doi.org/10.1093/femsml/uqac018113

Identification of Mirafiori lettuce big-vein virus and Lettuce big-vein associated virus infecting Lactuca sativa with symptoms of lettuce big-vein disease in Argentina

Lettuce big-vein disease (BVD) affects all major lettuce-producing areas of the world. The causal agent is Mirafiori lettuce big-vein virus (MLBVV), an ophiovirus transmitted by the soil-borne fungus Olpidium brassicae (Lot et al., 2002). MLBVV has been detected in many different areas of the world but never in Argentina. La Plata has about 700 ha of lettuce with a production of about 13 000 tonnes, and with about 70% of the total production from Buenos Aires Province. BVD has been detected in different areas in the north and west of the La Plata horticultural green belt. Many of the plants with BVD symptoms had leaf distortions of moderate severity, which affected their commercial value.Facultad de Ciencias ExactasFacultad de Ciencias Agrarias y Forestale

Identification of Mirafiori lettuce big-vein virus and Lettuce big-vein associated virus infecting Lactuca sativa with symptoms of lettuce big-vein disease in Argentina

Lettuce big-vein disease (BVD) affects all major lettuce-producing areas of the world. The causal agent is Mirafiori lettuce big-vein virus (MLBVV), an ophiovirus transmitted by the soil-borne fungus Olpidium brassicae (Lot et al., 2002). MLBVV has been detected in many different areas of the world but never in Argentina. La Plata has about 700 ha of lettuce with a production of about 13 000 tonnes, and with about 70% of the total production from Buenos Aires Province. BVD has been detected in different areas in the north and west of the La Plata horticultural green belt. Many of the plants with BVD symptoms had leaf distortions of moderate severity, which affected their commercial value.Facultad de Ciencias ExactasFacultad de Ciencias Agrarias y Forestale

Depression and microvascular complications predict poor goal achievement among Colombian patients with type 2 diabetes

Aims: Many patients with type 2 diabetes (DM2) in Latin American countries remain insufficiently controlled. We aimed to identify factors associated with persistent poor metabolic control in Colombian patients with DM2. Methods: Retrospective one-year follow-up cohort study of adult patients with DM2. The primary outcome was persistent poor metabolic control (PPMC): HbA1c level >8% in all measurements during follow-up. Secondary outcomes were intermittent poor metabolic control (IPMC) and good control (GC: simultaneous achievement of HbA1c, blood pressure and LDL cholesterol goals). Multiple demographic, clinical and laboratory variables were predictors in multivariable logistical models. Results: Of 399 patients included, 50 had the primary endpoint during follow-up. Older age was negatively associated with PPMC (OR 0.40, 95%CI 0.17-0.92 for extreme quartiles), even after multivariate adjustment. Depression and the presence of multiple microvascular complications were strongly associated with the secondary endpoint IPMC (multivariate OR respectively 4.2, 95%CI 1.08-16.4 for depression; 5.61, 95%CI 1.03-30.6 for microvascular complications). Being unemployed was associated with significantly less odds of achieving GC (multivariate OR 0.19, 95%CI 0.04-0.95). Conclusions: Age, depression, the presence of microvascular complications and employment status were associated with the success or failure of diabetes management. These factors were better correlates of therapeutic success than the pharmacological agent employed