48 research outputs found
Automated generation of flat tileable patterns and 3D reduced model simulation
The computational fabrication community is developing an increasing interest in the use of patterned surfaces, which can be designed to show ornamental and unconventional aesthetics or to perform as a proper structural material with a wide range of features. Geometrically designing and controlling the deformation capabilities of these patterns in response to external stimuli is a complex task due to the large number of variables involved. This paper introduces a method for generating sets of tileable and exchangeable flat patterns as well as a model-reduction strategy that enables their mechanical simulation at interactive rates. This method is included in a design pipeline that aims to turn any general flat surface into a pattern tessellation, which is able to deform under a given loading scenario. To validate our approach, we apply it to different contexts, including real-scale 3D printed specimens, for which we compare our results with the ones provided by a ground-truth solver
The future we want
Purpose â This paper aims to provide a description of the achievements of the United Nations (UN) Decade of Education for Sustainable Development (2005-2014) with a focus on higher education, and it describes some of the key issues which will guide sustainable development in the coming years. Design/methodology/approach â The paper initially presents an analysis of past developments, complemented by an assessment of the emphasis on sustainable development by the International Journal of Sustainability in Higher Education. In particular, it makes cross-references to the deliberations held at the UN Conference on Sustainable Development held in Rio de Janeiro, Brazil, in June 2012, with a special emphasis to the document âThe Future we Wantâ. It concludes by listing a set of suggestions and measures that both industrialised and developing countries may consider to translate the principles of sustainable development into reality. Findings â Sustainable development is and will continue to be a matter of substantial international interest and concern. The developments achieved over the past 20 years have been substantial, but there are still many gaps and need which need to be met, so as to improve its prospects in the next two decades. Originality/value â The paper provides useful insights which allow a better understanding of the role of universities in fostering sustainable development, and some of the key issues need to be considered, so as to allow things to move in the right direction
Peptic Ulcer Perforation as the First Manifestation of Previously Unknown Primary Hyperparathyroidism
A patient admitted for acute abdomen was incidentally found with elevated serum calcium level. In surgery, under conservative treatment of the hypercalcemia, a perforated duodenal ulcer was found and simple closure was performed. Postoperatively, calcium level continued to rise, parathyroid hormone was elevated and ultrasonographic examination showed a lesion in the right anterior neck, while serum gastrin level was normal, thus documenting the diagnosis of primary hyperparathyroidism. Conservative treatment had no effect on calcium level and the patient was subjected to emergency neck exploration, where a large parathyroid adenoma was removed. After surgery, calcium and PTH levels were normalized and the patient was discharged on the 5th postoperative day. Peptic ulcer and its complications are usual manifestations of primary hyperparathyroidism, with or without increased gastrin level. On the other hand, cases of a perforation of peptic ulcer as the first clinical manifestation of primary hyperparathyroidism are extremely rare
Adalimumab - an effective and promising treatment for patients with fistulizing Crohn's disease: a case series
Computationally efficient 3D analytical magnet loss prediction in surface mounted permanent magnet machines
This study proposes a computationally efficient analytical method, for accurate prediction of three-dimensional (3D) eddy current loss in the rotor magnets of surface mounted permanent magnet (SPM) machines considering slotting effect. Subdomain model incorporating stator tooth tips is employed to generate the information on radial and tangential time-derivatives of 2D magnetic field (eddy current sources) within the magnet. The distribution of the eddy current sources in 3D is established for the magnets by applying the eddy current boundary conditions and the Coulomb gauge imposed on the current vector potential. The 3D eddy current distributions in magnets are derived analytically by employing the method of variable separation and the total eddy current loss in the magnets are subsequently established. The method is validated by 3D time-stepped finite element analysis for 18-slot, 8-pole and 12-slot, 8-pole permanent magnet machines. The eddy current loss variations in the rotor magnets with axial and circumferential number of segmentations are studied. The reduction of magnet eddy current loss is investigated with respect to harmonic wavelength of the source components to suggest a suitable segmentation for the rotor magnets in SPM machines
Quality of Life Indices for Analysing Convergence in the European Union
GIANNIAS D., LIARGOVAS P. and MANOLAS G. (1999) Quality of life indices for analysing convergence in the European Union, Reg. Studies 33 , 27-35. This paper investigates convergence and tests it empirically across countries of the European Union between 1970 and 1990. Convergence is defined not only in terms of economic indicators, but also in terms of social and quality of life indicators. Real convergence is computed by evaluating a weighted average coefficient of variation based on economic and quality of life variables. The weights are based on an experts' opinion survey. Country rankings, based on the values of a composite quality of life index, are also constructed. The results confirm that real convergence was achieved between 1970-75 for most of the countries. Convergence stagnated between 1980-85 and then it increased. Southern European Member States did not exhibit similar patterns. GIANNIAS D., LIARGOVAS P. et MANOLAS G. (1999) L'analyse de la convergence au sein de l'Union europeenne a partir des indices de la qualite de la vie, Reg. Studies 33 , 27-35. Cet article cherche a examiner la notion de convergence et a l'evaluer empiriquement quant aux pays membres de l'Union europeenne entre 1970 et 1990. La notion de convergence s'exprime non seulement en fonction des clignotants economiques, mais aussi a partir des indices sociales et de la qualite de la vie. On calcule la convergence reelle en evaluant un coefficient de variation de la moyenne ponderee fonde sur des variables economiques et relatives a la qualite de la vie. Les ponderations proviennent d'une enqueâte des opinions des experts. Les pays sont classes en fonction des valeurs d'une indice composee de la qualite de la vie. Les resultats confirment que la convergence reelle avait ete atteinte entre 1970 et 1975 pour la plupart des pays. La convergence stagnait entre 1980 et 1985 pour redemarrer. Les pays-membres du sud de l'Europe n'ont pas fait preuve des tendances similaires. GIANNIAS D., LIARGOVAS P. und MANOLAS G. (1999) Lebensqualitatsindexe zur Analyse der Konvergenz in der EU, Reg. Studies 33 , 27-35. Dieser Aufsatz untersucht Konvergenz und uberpruft sie empirisch in Landern der ganzen EU fur den Zeitraum 1970-1990. Konvergenz wird nicht nur unter dem Aspekt wirtschaftlicher Indikatoren, sondern auch dem der Lebensqualitat- und Sozialindikatoren definiert. Wirkliche Konvergenz wird duch Bewertung gewichteter durchschnittlicher Koeffizienten der Unterschiede berechnet, die sich wirtschaftlichen und Lebensqualitatsvariablen beruhen. Gewichtung stutzt sich auf Untersuchung von Expertenansichten. Daruberhinaus werden Landerranglisten aufgestellt, die auf Werten eines zusammengesetzten Lebensqualitatsindex beruhen. Die Ergebnisse bestatigen, dass wahre Konvergenz in den meisten Landernim Zeitraum 1970-75 erreicht wurde, im Zeitraum 1980-85 jedoch stagnierte und danach zunahm. Sudeuropaische Mitgliedstaaten weisen keine derartigen Muster auf.European Union, Convergence, Quality Of Life Indices, Union Europeenne, Convergence, Indices De La Qualite De La Vie, Eu, Konvergenz, Lebensqualitatsindexe,
Usefulness of noninvasive detection of left ventricular diastolic abnormalities during isometric stress in hypertrophic cardiomyopathy and in athletes
We showed previously that the handgrip apexcardiographic test (HAT) is a
useful method for detecting left ventricular (LV) diastolic
abnormalities in patients with coronary artery disease and systemic
hypertension, This study evaluates the use of HAT for assessing the
prevalence and types of exercise-induced diastolic abnormalities in
patients with obstructive (n = 31) and nonobstructive (n = 35)
hypertrophic cardiomyopathy (HC) as well as its potential value for
separating healthy subjects and athletes from patients with HC. We
obtained a HAT in 66 consecutive patients with HC and in 72 controls (52
healthy volunteers and 20 athletes), A positive HAT was defined by the
presence of one of the following: (1) relative A wave to fetal height
(A/H) during or after handgrip >21% (compliance type), (2) total
apexcardiographic relaxation time (TART) >143 ms or the heart rate
corrected TART (TARTI) during handgrip <0.14, (relaxation type), (3)
both types present (mixed type), and (4) diastolic amplitude time index
(DATI = TARTI/[A/D]) during handgrip <0.27. Of the controls, only 1 of
52 healthy subjects and 1 of 20 athletes showed a positive HAT, whereas
of the total HC cohort 63 of 66 patients (95%) herd a positive result.
There was no significant difference in the distribution of these types
between obstructive and nonobstructive HC. Further, no LV diastolic
abnormalities were present in 10 of 35 patients (29%) with
nanobstructive HC at rest and in 3 of 35 patients (9%) during handgrip,
whereas of the patients with obstructive HC only 1 of 31 (3%) had no LV
diastolic abnormalities at rest and none during handgrip. Based on HAT
data, our study demonstrates that in HC (1) LV diastolic abnormalities
are very frequent during handgrip; (2) patients with nonobstructive HC
show significantly fewer LV diastolic abnormalities at rest than those
with obstructive HC; and (3) no significant difference exists between
obstructive and nonobstructive HC in the prevalence of types of
handgrip-induced LV diastolic abnormalities. Consequently, HAT appears
to be of clinical value as an additional tool for separating normal
patients and athletes from patients with HC. (C) 1998 by Excerpta
Medics, Inc
Identification of patients with coronary artery disease by assessing diastolic abnormalities during isometric exercise
Background: Previous clinical studies using invasive and noninvasive
methods have shown handgrip-induced diastolic abnormalities in patients
with coronary artery disease (CAD).
Hypothesis: The study was undertaken to determine the utility of Doppler
echo- and pressocardiography during handgrip in discriminating patients
with coronary artery disease (CAD) and in those with normal coronary
arteries.
Methods: Both methods were obtained in 96 patients with suspected CAD
within 24 h before coronary angiography. An abnormal handgrip-Doppler
was defined by an early (E) to late (A) transmittal flow velocities
ratio (E/A) < 1 during handgrip and a positive handgrip
pressocardiographic test (HAT) by an abnormal increase in the A
wave/total excursion or prolongation of the absolute or relative
(heart-rate corrected) total relaxation time during isometric exercise.
Results: Of the 96 patients studied, 23 had normal coronary arteries and
73 showed CAD. In patients with normal coronary arteries,
handgrip-Doppler showed an abnormal average E/A at rest and during
handgrip, whereas all variables of HAT were within normal limits. In
patients with CAD, handgrip-Doppler showed only a moderate
handgrip-induced increase in average A (+19%, p < 0.001), whereas HAT
showed a significant (p < 0.001) increase in mean A wave/total excursion
(+ 60%) and decrease in the relative total relaxation time (- 17%).
Furthermore, handgrip-Doppler and HAT were abnormal in 15 of 23 (65%
specificity 35%) and the HAT in 5 of 23 (22%, specificity 78%)
patients with normal coronary arteries, as well as in 57 of 73
(sensitivity 78%) and 69 of 73 (95%) patients with CAD.
Conclusions: Our study demonstrates that these noninvasive stress tests
can become a useful new diagnostic modality for detecting patients with
unknown or suspected CAD