Sensing the Deadliest Toxin: Technologies for Botulinum Neurotoxin Detection

Sensitive and rapid detection of botulinum neurotoxins (BoNTs), the most poisonous substances known to date, is essential for studies of medical applications of BoNTs and detection of poisoned food, as well as for response to potential bioterrorist threats. Currently, the most common method of BoNT detection is the mouse bioassay. While this assay is sensitive, it is slow, quite expensive, has limited throughput and requires sacrificing animals. Herein, we discuss and compare recently developed alternative in vitro detection methods and assess their ability to supplement or replace the mouse bioassay in the analysis of complex matrix samples

From Bengal to British Guiana The emigration of Indian indentured labour, 1854-1884

SIGLEAvailable from British Library Document Supply Centre- DSC:D70728/82 / BLDSC - British Library Document Supply CentreGBUnited Kingdo

The effects of vegetation structure on the birds in a tropical savanna woodland in north-eastern Australia

Management of the dynamics of woody vegetation in Australia’s tropical savannas is a vexing issue for both pastoralists and conservation biologists. In savanna regions around the world, increasing density of woody vegetation contributes to declines in pastoral productivity, but its effects on native fauna are largely unknown. In this paper we examine the avifauna in savanna woodlands of varying structure in the Desert Uplands bioregion, Queensland. Vegetation cover maps derived from aerial photographs were used to choose 60 sites, across 4 cattle stations. We sampled sites mapped at 30–45% and 45–60% foliage cover, and areas which previously had these levels of cover but had been mechanically modified, both by broad scale clearing and selective thinning. Between May and June 2004, we measured a range of habitat variables and sampled the birds at each site. Bird species composition varied significantly between treatments. Bird richness and frequency was greatest in intact vegetation. Thirteen species of birds were most frequently encountered in sites with 30–45% canopy cover, compared with 10 species in the 45–60% cover sites, 4 species in the thinned sites and 7 in the cleared sites. Our results suggest that increasing density of woody vegetation in savanna woodland may be to the advantage of some savanna bird species. Mechanical modification to reduce woody vegetation appears to also benefit some common, widespread species, but has a generally negative overall effect on bird species richness