Frequently hypercyclic semigroups

We study frequent hypercyclicity in the context of strongly continuous semigroups of operators. More precisely, we give a criterion (sufficient condition) for a semigroup to be frequently hypercyclic, whose formulation depends on the Pettis integral. This criterion can be verified in certain cases in terms of the infinitesimal generator of semigroup. Applications are given for semigroups generated by Ornstein-Uhlenbeck operators, and especially for translation semigroups on weighted spaces of $p$-integrable functions, or continuous functions that, multiplied by the weight, vanish at infinity

Analyticity of a class of degenerate evolution equations on the canonical simplex of Rd\R^d arising from Fleming--Viot processes

We study the analyticity of the semigroups generated by a class of degenerate second order differential operators in the space $C(S_d)$, where $S_d$ is the canonical simplex of $\R^d$. The semigroups arise from the theory of Fleming--Viot processes in population genetics.Comment: 32 page

Off pump treatment of aortic arch rupture: extraanatomic hybrid reconstruction

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On vector-valued Schrödinger operators with unbounded diffusion in Lp spaces

We prove generation results of analytic strongly continuous semigroups on Lp(Rd, Rm) (1 < p< ∞) for a class of vector-valued Schrödinger operators with unbounded coefficients. We also prove Gaussian type estimates for such semigroups

Platelet Activating Factor Synthesis and Metabolism in Intestinal Ischaemia-Reperfusion Injury

The object of this study was to characterize the synthesis and metabolism of platelet activating factor (PAF) by intestinal mucosa subjected to ischaemia–reperfusion injury. Canine intestinal mucosa produced 16:0-PAF, 18:0-PAF, and high levels of the corresponding lyso- PAF metabolites. Three h of intestinal ischaemia and ischaemia followed by 1 h of reperfusion did not affect the synthesis or metabolism of PAF by intestinal mucosa. Intestinal mucosa elaborated a factor that rapidly hydrolyzes PAF to lyso-PAF. The observed hydrolysis rate was not altered by ischaemia or ischaemia and reperfusion. In conclusion, this study suggests that intestinal mucosa produces PAF and rapidly hydrolyzes PAF. The PAF synthesis and metabolism rates of intestinal mucosa is not altered by ischaemia reperfusion in this model under the imposed conditions

Atypical polypoid adenomyoma follow-up and management: Systematic review of case reports and series and meta-analysis

BACKGROUND: Atypical polypoid adenomyoma (APA) is a rare uterine tumor typically found in fertile age and associated with infertility. Among young nullipara women, conservative treatment is proposed despite the high recurrence rate and the association with endometrial cancer.Our aim was to assess the risk of recurrence with different conservative treatments in fertile ages and the prevalence of malignant or pre-malignant associated lesions to better address an adequate patient counselling when treatment modalities are discussed. METHODS: This study is a systematic review and meta-analysis of case reports and case series about APA management and follow-up. A literature search was carried from Medline and Scopus for studies published from January 1, 1980 to December 31, 2018. RESULTS: We included 46 observational studies and 296 cases in fertile women. The prevalence of APA relapse was 44% (CI.95 33-57%) and was lower in cases treated with operative hysteroscopy (22%; CI.95 11-39%) than in cases treated with blind curettage and polypectomy (38%; CI.95 15-67%). The prevalence of the concomitant or during the follow-up diagnosis of endometrial carcinoma was 16% (CI.95 9-29%). The risk of cancer development during follow-up was significantly less in cases treated with histeroscopy (10.56% new cumulative diagnosis at 5 years follow up; CI.95 0-23.7%) than blind curettage and polypectomy (35.5% new cumulative diagnosis at 5 years; CI.95 11.65-52.92%; P\u200a<\u200a.05). Medical treatment with medroxyprogesterone acetate after surgery does not reduce APA recurrence. Pregnancy was observed in 79% cases in which the desire was expressed. CONCLUSION: This review suggests that conservative treatment performed by operative hysteroscopy is the optimal choice because it lowers the risk of recurrence, improves the accuracy of concomitant carcinoma or hyperplasia diagnosis, and leaves the possibility of future pregnancies

Data-driven curation, learning and analysis for inferring evolving IoT botnets in the wild

The insecurity of the Internet-of-Things (IoT) paradigm continues to wreak havoc in consumer and critical infrastructure realms. Several challenges impede addressing IoT security at large, including, the lack of IoT-centric data that can be collected, analyzed and correlated, due to the highly heterogeneous nature of such devices and their widespread deployments in Internet-wide environments. To this end, this paper explores macroscopic, passive empirical data to shed light on this evolving threat phenomena. This not only aims at classifying and inferring Internet-scale compromised IoT devices by solely observing such one-way network traffic, but also endeavors to uncover, track and report on orchestrated "in the wild" IoT botnets. Initially, to prepare the effective utilization of such data, a novel probabilistic model is designed and developed to cleanse such traffic from noise samples (i.e., misconfiguration traffic). Subsequently, several shallow and deep learning models are evaluated to ultimately design and develop a multi-window convolution neural network trained on active and passive measurements to accurately identify compromised IoT devices. Consequently, to infer orchestrated and unsolicited activities that have been generated by well-coordinated IoT botnets, hierarchical agglomerative clustering is deployed by scrutinizing a set of innovative and efficient network feature sets. By analyzing 3.6 TB of recent darknet traffic, the proposed approach uncovers a momentous 440,000 compromised IoT devices and generates evidence-based artifacts related to 350 IoT botnets. While some of these detected botnets refer to previously documented campaigns such as the Hide and Seek, Hajime and Fbot, other events illustrate evolving threats such as those with cryptojacking capabilities and those that are targeting industrial control system communication and control services

Heritability of insulin sensitivity and lipid profile depend on BMI: evidence for gene–obesity interaction

Evidence from candidate gene studies suggests that obesity may modify genetic susceptibility to type 2 diabetes and dyslipidaemia. On an aggregate level, gene-obesity interactions are expected to result in different heritability estimates at different obesity levels. However, this hypothesis has never been tested. The present study included 2,180 British female twins. BMI was used as an index of general obesity. Outcome measures were insulin sensitivity (indexed by quantitative insulin-sensitivity check index [QUICKI]) and fasting plasma lipid profile. Structural equation modelling was used to test whether BMI interacted with latent genetic and environmental effects to impact on the outcome measures. Genetic influences on triacylglycerol increased with BMI (p <0.001) whereas the unique environmental influence on QUICKI decreased with BMI (p <0.001), resulting in a higher heritability estimate for both measures at higher BMI levels. This was further illustrated by stratified analysis in twin pairs concordant for normal weight and twin pairs concordant for overweight. Heritability was 19 percentage points higher for triacylglycerol (p <0.001) and 31 percentage points higher for QUICKI (p <0.01) among twins concordant for overweight than among twins concordant for normal weight. BMI had no moderator effect on the latent genetic and environmental factors for total cholesterol and HDL-cholesterol. Our results suggest that the expression of genes influencing triacylglycerol and insulin sensitivity can vary as a function of obesity status. The substantial increases in the genetic contribution to the total variance in insulin sensitivity and triacylglycerols at higher BMIs may prove extremely valuable in the search for candidate genes