Development of an XSPEC-Based Spectral Analysis System for the Coded-Aperture Hard X-ray Balloon Payload EXITE2

We present the spectral analysis system for the second-generation Energetic X-ray Imaging Telescope Experiment (EXITE2) balloon payload. EXITE2 is an imaging hard X-ray telescope using a coded-aperture mask and a NaI/CsI phoswich detector operating in the energy range 20--600 keV. The instrument was flown on a high-altitude scientific balloon from Ft. Sumner, NM on 1997 May 7-8. We describe the details of the EXITE2 spectral analysis system, with emphasis on those aspects peculiar to coded-aperture instruments. In particular, we have made our analysis compatible with the standard X-ray spectral fitting package XSPEC by generating a response matrix in the appropriate format including all the effects of a coded-aperture system. The use of XSPEC, which may be a first for coded-aperture data, permits great flexibility in the fitting of spectral models. The additional effects of our phoswich system, or any other detector-specific considerations, may be easily included as well. We test our spectral analysis using observations of the Crab Nebula, and find that the EXITE2 Crab spectrum is consistent with those recorded by previous instruments operating in this energy range.Comment: 17 pages LaTeX, 6 figures, accepted to Astroparticle Physic

High prevalence of anelloviruses in vitreous fluid of children with seasonal hyperacute panuveitis.

Seasonal hyperacute panuveitis (SHAPU) is a potentially blinding ocular disease occurring in Nepal that principally affects young children. Random amplification of partially purified vitreous fluid (VF)-derived nucleic acid revealed the presence of human anelloviruses in VF of SHAPU patients. In a comparative study of patients with different ocular pathologies, SHAPU patients were at highest risk of harboring anelloviruses in their eyes. The majority of SHAPU patients had multiple anelloviruses in their VF. The ocular anellovirus load in SHAPU and non-SHAPU patients did not differ and no SHAPU-specific anellovirus variant was detected. Analysis of paired serum and VF samples from SHAPU and non-SHAPU patients showed that the anellovirus detected in VF samples most likely originated from the systemic viral pool during viremia, potentially through breakdown of the blood-ocular barrier. The detection of anelloviruses in VF samples of uveitis patients, profoundly so in SHAPU patients, is imperative and warrants elucidation of its clinical significance

Occurrence and diversity of Xanthomonas campestris pv. campestris in vegetable brassica fields in Nepal

Black rot caused by Xanthomonas campestris pv. campestris was found in 28 sampled cabbage fields in five major cabbage-growing districts in Nepal in 2001 and in four cauliflower fields in two districts and a leaf mustard seed bed in 2003. Pathogenic X. campestris pv. campestris strains were obtained from 39 cabbage plants, 4 cauliflower plants, and 1 leaf mustard plant with typical lesions. Repetitive DNA polymerase chain reaction-based fingerprinting (rep-PCR) using repetitive extragenic palindromic, enterobacterial repetitive intergenic consensus, and BOX primers was used to assess the genetic diversity. Strains were also race typed using a differential series of Brassica spp. Cabbage strains belonged to five races (races 1, 4, 5, 6, and 7), with races 4, 1, and 6 the most common. All cauliflower strains were race 4 and the leaf mustard strain was race 6. A dendrogram derived from the combined rep-PCR profiles showed that the Nepalese X. campestris pv. campestris strains clustered separately from other Xanthomonas spp. and pathovars. Race 1 strains clustered together and strains of races 4, 5, and 6 were each split into at least two clusters. The presence of different races and the genetic variability of the pathogen should be considered when resistant cultivars are bred and introduced into regions in Nepal to control black rot of brassicas

Living knowledge of the healing plants: Ethno-phytotherapy in the Chepang communities from the Mid-Hills of Nepal

Contribution of indigenous knowledge in developing more effective drugs with minimum or no side effects helped to realise importance of study of indigenous remedies and the conservation of biological resources. This study analysed indigenous knowledge regarding medicinal plants use among the Chepang communities from ward number 3 and 4 of Shaktikhor Village Development Committee located in the central mid hills of Nepal. Data were collected in a one-year period and included interviews with traditional healers and elders. Chepangs are rich in knowledge regarding use of different plants and were using a total 219 plant parts from 115 species including one mushroom (belonging 55 families) for medicinal uses. Out of these, 75 species had 118 different new medicinal uses and 18 of them were not reported in any previous documents from Nepal as medicinal plants. Spiritual belief, economy and limitation of alternative health facilities were cause of continuity of people's dependency on traditional healers. Change in socio-economic activities not only threatened traditional knowledge but also resource base of the area. Enforcement of local institution in management of forest resources and legitimating traditional knowledge and practices could help to preserve indigenous knowledge

Dynamic Scaling of an Adsorption-Diffusion Process on Fractals

A dynamic scaling of a diffusion process involving the Langmuir type adsorption is studied. We find dynamic scaling functions in one and two dimensions and compare them with direct numerical simulations, and we further study the dynamic scaling law on fractal surfaces. The adsorption-diffusion process obeys the fracton dynamics on the fractal surfaces.Comment: 9 pages, 7 figure

Dental Prosthetic Status and Prosthetic Needs of Patients Visiting Gandaki Medical College, Western Nepal

Introduction: The study of prosthetic status and prosthetic need will help us to find out the degree of treatment required in the population which will help to frame the health care services. Objective: The objective of the study was to find out the prosthetic status, prosthetic need in different age groups and their correlation with socio-economic status in patients visiting Department of Prosthodontics, College of Dental Surgery, Gandaki Medical College, Pokhara, Nepal. Materials and Methods: The patients visiting Department of Prosthodontics, College of Dental Surgery, Gandaki Medical College, Pokhara, Nepal were screened. The demographic profile of the patients was obtained and clinical examination for prosthetic status and prosthetic need was done based on WHO method. Results: There were total of 309 patients who visited the department during the study period. There were 133 (43%) male and 176 (57%) female patients. The majority of patients had no prosthesis in upper arch 78.6% and 83.8% in lower arch. The number of patients with replacement of missing teeth in upper arch was 66 (21.4%) and in lower arch were 50 (16.2%). There were 159 (51.5%) of patients requiring one or the other form of prosthesis in upper arch and 161 (52.1%) of patients in lower arch. Conclusion: The majority of patients had no prosthesis 78.6% in upper arch and 83.8% in lower arch. The need of prosthesis was 51.5% in upper arch and 52.1 % in lower arch

Airborne Endotoxin Concentrations in Homes Burning Biomass Fuel

BACKGROUND: About half of the world's population is exposed to smoke from burning biomass fuels at home. The high airborne particulate levels in these homes and the health burden of exposure to this smoke are well described. Burning unprocessed biological material such as wood and dried animal dung may also produce high indoor endotoxin concentrations.OBJECTIVE: In this study we measured airborne endotoxin levels in homes burning different biomass fuels. Methods: Air sampling was carried out in homes burning wood or dried animal dung in Nepal (n = 31) and wood, charcoal, or crop residues in Malawi (n = 38). Filters were analyzed for endotoxin content expressed as airborne endotoxin concentration and endotoxin per mass of airborne particulate.RESULTS: Airborne endotoxin concentrations were high. Averaged over 24 hr in Malawian homes, median concentrations of total inhalable endotoxin were 24 endotoxin units (EU)/m(3) in charcoal-burning homes and 40 EU/m(3) in wood-burning homes. Short cooking-time samples collected in Nepal produced median values of 43 EU/m(3) in wood-burning homes and 365 EU/m(3) in dung-burning homes, suggesting increasing endotoxin levels with decreasing energy levels in unprocessed solid fuels.CONCLUSIONS: Airborne endotoxin concentrations in homes burning biomass fuels are orders of magnitude higher than those found in homes in developed countries where endotoxin exposure has been linked to respiratory illness in children. There is a need for work to identify the determinants of these high concentrations, interventions to reduce exposure, and health studies to examine the effects of these sustained, near-occupational levels of exposure experienced from early life