Spectral Mixture Analysis for Monitoring and Mapping Desertification Processes in Semi-arid Areas in North Kordofan State, Sudan

Multi-temporal remotely sensed data (MSS, TM and ETM+)were used for monitoring and mapping the desertification processes in North Kordofan State, Sudan.A liear mixture model (LMM) was adopted to analyse and the desertification proccesses by using the image endmembers. interpretation of ancillary data and field observation was adopted to verfiy the role of human impacts in the temporal changes in the study area. The findings of the study proved the powerfull of remotely sensed data in monitoring and mapping the desertification processes and come out with valuable recommendations which could contribute positively in reducing desert encroachment in the area

Spectral Mixture Analysis for Monitoring and Mapping Desertification Processes in Semi-arid Areas in North Kordofan State, Sudan

Multi-temporal remotely sensed data (MSS, TM and ETM+)were used for monitoring and mapping the desertification processes in North Kordofan State, Sudan.A liear mixture model (LMM) was adopted to analyse and the desertification proccesses by using the image endmembers. interpretation of ancillary data and field observation was adopted to verfiy the role of human impacts in the temporal changes in the study area. The findings of the study proved the powerfull of remotely sensed data in monitoring and mapping the desertification processes and come out with valuable recommendations which could contribute positively in reducing desert encroachment in the area

Smoking counseling practices of physicians in the United Arab Emirates

Background. Despite the cost effectiveness of physician smoking cessation counseling, many physicians do not adhere to current clinical practice guidelines. Methods. A cross-sectional mail survey was conducted in a sample of general practitioners in the United Arab Emirates (UAE), emirates of Sharjah, Dubai and Abu Dhabi, to document cessation-counseling practices and identify correlates of these activities. Results. Of 391 eligible GPs, 218 (56%) completed the questionnaire. Despite favorable beliefs/attitudes about cessation counseling, less than half of GPs (47%) indicated that they have the skills to help their patients quit smoking and only 24% knew of community resources to refer patients to. GPs who perceived physician barriers in offering smoking counseling as very important were significantly less likely to ascertain smoking status of most of their patients (OR: 0.28, 95% CI: 0.09,0.88). Moreover, high self-efficacy and favorable beliefs/attitudes were significantly associated with high level of counseling completeness (OR: 4.44, 95% CI: 1.21, 16.37; OR: 3.78, 95% CI: 1.25, 11.35; respectively). Conclusion. Support, training and intervention programs to overcome lack of awareness and knowledge, unfavorable beliefs/attitudes, and low self-efficacy could increase and enhance cessation-counseling practices among general practitioners in the UAE. © 2010, SAGE Publications. All rights reserved

TOPICAL AND SYSTEMIC DERMAL CARRIERS FOR PSORIASIS

Psoriasis is a non-infectious, dry, inflammatory (autoimmune) skin disorder. Treatment approaches include phototherapy, topical, oral and other systemic drug delivery. However, owing to the side effects and incomplete cure accompanying the oral administration as well as phototherapy, the topical route seemed to be more satisfactory for the medical team. Dermal treatment ensuring percutaneous penetration is now highly recommended in topical indications for psoriatic patients, which can be achieved using pharmaceutical carriers. Several carrier systems loaded with antipsoriatic drugs have demonstrated promising results, with some of them strictly being confined to the skin and others allowing for systemic involvement also. The evolution in this area will present a more useful and safer therapy by minimizing the drugs' degradation and loss, and increasing their bioavailability and effectiveness. Since patients require at least three topical applications for almost a 1-year period to gain health benefit, a reduction in the cost of the treatment will be of real value. A distinction of these carriers is made in the current review, to allow the choice of the most suitable pharmaceutical carrier for psoriatic patients requiring either local and/or systemic involvement

Detection of FXIII gene V34L and fibrinogen β-gene -455G/A polymorphisms among Saudi Arabia population via polymerase chain reaction-reverse hybridization technique

FXIII gene Val34Leu variant appears to be associated with decreased risk of myocardial infarction and venous thromboembolism as well as with increased risk of intracerebral hemorrhage. Fibrinogen β-gene SNP -455G/A are associated with differences in the plasma levels of fibrinogen and severity of arterial disease. The aim of the present work was to study the prevalence of FXIII gene V34L and Fibrinogen β-gene -455G/A SNPs in Saudi population. Among 200 blood samples randomly collected from unrelated healthy Saudi subjects, FXIII gene V34L and Fibrinogen β-gene -455G/A SNPs were genotyped via cardiovascular disease (CVD) StripAssay (ViennaLab, Austria. Homozygous (V/V) and heterozygous (V/L) genotypes were detected with 96 and 4%, respectively, among FXIII gene V34L genotypes, whereas (L/L) genotype was not found. The allele frequency was 0.98 for V allele and 0.02 for L allele. Three genotypes of Fibrinogen β-gene -455G/A SNP (GG, GA and AA) were obtained and its prevalence (%) was 70, 25 and 5, respectively. The frequency of G allele was 0.825 and 0.175 for A allele. Prevalence of FXIII gene Vl34L polymorphism and its allele frequency are in line with other Asian populations. Distribution of β-gene -455G/A genotypes and allele frequency are in accordance with previous reports in different ethnic groups. This is the first time to report these polymorphisms in Saudi Arabia population. This study provides valuable information on Saudi genetic background in comparison with other populations. In addition, it serves as a template for future clinical research involving cardiovascular and cerebrovascular diseases.Key words: FXIII gene V34L, fibrinogen β-gene -455G/A, polymorphisms, Saudi Arabia

Simulation model of ACO, FLC and PID controller for TCP/AQM wireless networks by using MATLAB/Simulink

The current work aims to develop a suitable design for control systems as part of a queue management system using the transmission control protocol/and active queue management (TCP/AQM) protocol to handle the expected congestion in the network. The research also aims to make a comparison between the different control methods, including the traditional proportional integral derivative (PID) and the expert fuzzy logic control (FLC), as well as the optimal ant colony optimization (ACO) that is used according to the performance improvement criteria to reach the best values for parameters the traditional controller (kd, ki, k p), where the addition of the performance indicator time-weighted absolute error (ITAE) was adopted. The use of this method without any other optimization algorithm that can be applied to adjust the parameters of the PID to verify the possibility of improving performance and enhance that with experience and to know the level of improvement for this particular system being the subject of the study. The results showed the superiority of the optimal ACO over both the FLC expert and the conventional PID, as well as the superiority of the FLC expert over the traditional PID

Novel Green Synthesis and Characterization of Nanopolymer Porous Gold Oxide Nanoparticles

Purpose: To develop a novel approach to green synthesis of nano-polymer porous gold oxide nanoparticles, and examine the effects of the temperatures on their surface.Methods: Green synthesis of nano-polymer porous gold oxide nanoparticles (GONPs) using cetyle trimethylammonium bromide (CTAB) surfactant with a mixture of Olea europaea fruit and Acacia Nilotica extracts, was performed using sol-gel method. The nanoporous particles were characterized by UV (ultraviolet (UV) visible spectroscopy and dynamic light scattering (DLS) while a zetasizer was applied to determine their average particle size. Their surface morphology and shape were assessed by transmission electron microscopy (TEM) and scanning election microscopy (SEM) while surface area was measured using nitrogen gas adsorption method.Results: TEM and SEM images showed a smooth, cylindrical or spherical, and cluster shapes, and porous surface morphology. Increase in calcination temperature resulted in increase in surface area and pore volume of nanoparticles. This feature yielded GONPs that were unique with a high surface area of 146.706 m2/g.Conclusion: The approach used in this study constitutes a new and rapid green synthesis of porous nanoparticles of gold oxide under simple conditions. Furthermore, increase in GONPs surface area is enhanced by increase in calcination temperature.Keywords: Gold oxide, Nanoporous, Green synthesis, Olea europaea, Acacia Nilotica, Surface area, Nanopolymer, Surface morpholog

Association between polymorphisms of SLC6A3 and DRD1 genes and autism among Saudi Arabia Taif population using PCR-restriction fragment length polymorphism (PCR- RFLP)

The prevalence of autism in Saudi Arabia is 18 per 10,000, higher than the 13 per 10,000 reported in developed  countries. The etiology of autism is still not completely understood. Different studies support the involvement  of dopaminergic neurotransmitter system in the etiology of autism. Several lines of evidences suggest the role of some dopamine related genes, such as DRD1 and SLC6A3 in the etiology of autism. The aim of the present  work was to study the possible role of rs2550936 A/C polymorphism at SLC6A3 locus as well as rs4532 A/G  polymorphism at DRD1 locus in the etiology of autism among Saudi population. The polymorphisms of DRD1  and LC6A3 were genotyped in the case-control study using polymerase chain reaction-restriction fragment  length polymorphism (PCR-RFLP) technique. Significant association as risk factor was found between autism  and GA genotype of DRD1 [OR = 3.5 CI (1.04, 12.41*)] as well as CA genotype of SLC6A3 [OR = 2.53 CI  (1.03, 6.26*)], while CC genotype of SLC6A3 revealed protective effect. In conclusion, possible risk  genotypes  for autism in the DRD1 and SLC6A3 genes were observed. This is the first report in Saudi Arabia  population and Arab world. Therefore further investigations of these markers and other SNPs of SLC6A3 and  DRD1 genes are considered in large replication samples with other causal factors to enable positive  identification of risk genotypes and generalize obtained results.Key words: Etiology, polymorphism, autism, genotype

Characterization of silver nanoparticles prepared by wet chemical method and their antibacterial and cytotoxicity activities

Purpose: To investigate the efficiency of silver nanoparticles synthesized by wet chemical method, and evaluate their antibacterial and anti-cancer activities.Methods: Wet chemical method was used to synthesize silver nanoparticles (AgNPs) from silver nitrate, trisodium citrate dehydrate (C6H5O7Na3.2H2O) and sodium borohydride (NaBH4) as reducing agent. The AgNPs and the reaction process were characterized by UV–visible spectrometry, zetasizer, transmission electron microscopy (TEM) and scanning electron microscopy (SEM) equipped with energy dispersive spectroscopy (EDS). The antibacterial and cytotoxic effects of the synthesized nanoparticles were investigated by agar diffusion method and MTT assay respectively.Results: The silver nanoparticles formed were spherical in shape with mean size of 10.3 nm. The results showed good antibacterial properties, killing both Gram-positive and Gram-negative bacteria, and its aqueous suspension displayed cytotoxic activity against colon adenocarcinoma (HCT-116) cell line.Conclusion: The findings indicate that silver nanoparticles synthesized by wet chemical method demonstrate good cytotoxic activity in colon adenocarcinoma (HCT-116) cell lines and strong antibacterial activity against various strains of bacteria.Keywords: Wet chemical, Silver nanoparticles, Characterization, Diffusion method, Antibacterial, Cytotoxic activit

Land-Use Land-Cover Change Detection Using Geospatial Techniques in Zalingei, Central Darfur, Sudan

Using remote sensing for land use and land cover (LULC) is essential for systems that help people make decisions because it gives valuable information about space and time. A study was conducted in Zalingei, Sudan, to analyze the changes in LULC over 30 years from 1991 to 2021 using multi-temporal Landsat images. Thematic Mapper (TM) and Operational Land Imager (OLI) were classified using the supervised classification method. The pictures were divided into four groups based on how the land was used: residential areas, bodies of water, vegetation cover, and bare land. Results showed that the residential area increased by 20.74% while the water body increased by 2.32%. However, the vegetation cover decreased by 0.7%, and bare land decreased by 22.37%. The changes were caused by people, which shows how vital good land management practices and involvement from the local community are for reducing LULC change. So, to reduce LULC change in the study area, proper land management practices and active participation from the local community are needed. The study concluded that remote sensing technology is an effective tool for assessing and mapping land use and land cover changes and providing valuable information for decision support systems