Ultra stable high power laser for the VIRGO project

No abstract availabl

EDN1 Lys198Asn is Associated with Diabetic Retinopathy in Type 2 Diabetes

Purpose: We tested the hypothesis that genetic variants in vasoactive and angiogenic factors regulating the retina vasculature contribute to the development of diabetic retinopathy (DR). Methods: A case-control study was performed to study the genetic association between DR and polymorphic variants of EDN1 (Lys198Asn), LTA (IVS1–80C>A, IVS1–206G>C, IVS1–252>G), eNOS (Glu298Asp), and ITGA2 (BgI II) in a Chinese population with type 2 diabetes mellitus. A well defined population with type 2 diabetes, consisting of 127 controls and 216 DR patients, was recruited. Results: A higher frequency of the Asn/Asn genotype of EDN1 was found in individuals with at least 10 years of diabetes and no retinopathy (controls) compared with DR patients with any duration of diabetes (DR: 2.3%; control: 11.0%; p=0.0002). The Asn allele was also more frequent in controls than DR patients (DR: 16.4%; control: 29.5%; p=0.007). Multiple logistic regression analysis showed that the Asn/Asn genotype was the factor most significantly associated with reduced risk of DR (odds ratio=0.19; 95% CI: 0.07-0.53; p=0.002) and with late onset of diabetes (Asn/Asn: 59 years; Lys/Lys + Lys/Asn: 53 years; p=0.02). Moreover, the Lys/Lys genotype was more common among patients with nonproliferative (75.7%) than proliferative DR (56.9%; p=0.008). The distributions of Lys198Asn alleles in hypertension did not differ from normotensive subjects. No associations between DR and polymorphisms of LTA, eNOS, or ITGA2 were detected, and there were no detectable gene-gene or gene-environmental interactions among the polymorphisms.Conclusions The Asn/Asn genotype of EDN1 was associated with a reduced risk of DR and with delayed onset of type 2 diabetes

Exact diagonalization of the generalized supersymmetric t-J model with boundaries

We study the generalized supersymmetric $t-J$ model with boundaries in three different gradings: FFB, BFF and FBF. Starting from the trigonometric R-matrix, and in the framework of the graded quantum inverse scattering method (QISM), we solve the eigenvalue problems for the supersymmetric $t-J$ model. A detailed calculations are presented to obtain the eigenvalues and Bethe ansatz equations of the supersymmetric $t-J$ model with boundaries in three different backgrounds.Comment: Latex file, 32 page

The Virgo interferometric gravitational antenna

Submitted to: Class. Quantum Grav.The interferometric gravitational wave detectors represent the ultimate evolution of the classical Michelson interferometer. In order to measure the signal produced by the passage of a gravitational wave, they aim to reach unprecedent sensitivities in measuring the relative displacements of the mirrors. One of them , the 3-km-long Virgo gravitational wave antenna, which will be particularly sensitive in the low frequency range (10-100 Hz), is presently in its commissioning phase. In this paper the various techniques developed in order to reach its target extreme performance are outlined

The status of VIRGO

In this paper the main characteristics of the interferometric gravitational waves detector Virgo are presented as well as its present status and perspectives

Interferometric detectors of gravitational waves on Earth: the next generations

International audienceThe interferometric detectors of gravitational waves of first generation are now taking data. A first detection might be possible with these instruments, but more sensitive detectors will be needed to start the gravitational wave astronomy. The interferometers of second generation will improve the sensitivity by a factor ten, allowing to explore a universe volume 1000 times larger. The technology is almost ready and the construction will start at the beginning of next decade. The community of the physicists involved in the field has also started to make plans for third generation detectors, for which a long term technology development will be required. The plans for the upgrades of the existing detectors and the scenario for the evolution of the field will be reviewed in this paper

LIGO and VIRGO: large interferometers searching for gravitational waves

International audienceThe largest interferometric detectors for gravitational waves, LIGO and Virgo, have reached (or are close to) the design sensitivity and have started taking science data. The operation of such detectors is reviewed and the expected sources and detection rates are discussed. LIGO and Virgo might make the first detection, but more advanced detectors will be needed to truly open the field of gravitational wave astronomy: the current ideas and plans for the upgrades of the existing interferometers are presented

The gravitational wave detector VIRGO

International audienc