63 research outputs found

    Методичне підгрунття та адміністративно-управлінські засади вдосконалення операційно-виробничої системи та організаційної структури девелоперської компанії

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    The article analyzes and improves scientific methodical approaches and applied tools for choosing the options for organizing a construction project throughout the investment cycle, including design, design, preparation and construction. The content and structure of the stages of the building development project as a specific resource-time environment has been redesigned, integrating the organizational-technological capabilities and economic interests of its leading non-qualified participants into the outdated scientific and methodological basis of construction preparation.В статті  проаналізовано та вдосконалено науково-методичні підходи та прикладні інструментарії для вибору варіантів організації будівельного девелоперського проекту впродовж всього інвестиційного циклу, включаючи задум, проектування, підготовку та будівництво.  Переналаштовано зміст та структури етапів будівельного девелоперського проекту як специфічне  ресурсно-часове  середовища, що інтегрує організаційно-технологічні можливості та економічні інтереси його провідних учасників, що не може готуватись,  втілюватись на застарілій   науково-методичній базі підготовки будівництва

    Robust imaging of hippocampal inner structure at 7T: in vivo acquisition protocol and methodological choices

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    International audienceOBJECTIVE:Motion-robust multi-slab imaging of hippocampal inner structure in vivo at 7T.MATERIALS AND METHODS:Motion is a crucial issue for ultra-high resolution imaging, such as can be achieved with 7T MRI. An acquisition protocol was designed for imaging hippocampal inner structure at 7T. It relies on a compromise between anatomical details visibility and robustness to motion. In order to reduce acquisition time and motion artifacts, the full slab covering the hippocampus was split into separate slabs with lower acquisition time. A robust registration approach was implemented to combine the acquired slabs within a final 3D-consistent high-resolution slab covering the whole hippocampus. Evaluation was performed on 50 subjects overall, made of three groups of subjects acquired using three acquisition settings; it focused on three issues: visibility of hippocampal inner structure, robustness to motion artifacts and registration procedure performance.RESULTS:Overall, T2-weighted acquisitions with interleaved slabs proved robust. Multi-slab registration yielded high quality datasets in 96 % of the subjects, thus compatible with further analyses of hippocampal inner structure.CONCLUSION:Multi-slab acquisition and registration setting is efficient for reducing acquisition time and consequently motion artifacts for ultra-high resolution imaging of the inner structure of the hippocampus

    The overlap between vascular disease and Alzheimer’s disease - lessons from pathology

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    INFLUENCE OF COLD ROLLING TO THE TEXTURE PARAMETER OF PURE HAFNIUM AND ZIRCONIUM

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    Results of X-ray investigations of dependence of the crystallographic texture of hafnium and zirconium on degrees of cold rolling are presented. To obtain numerical principles, the method of inverse pole figures (IPF) with calculation of the texture parameters of Kearns (TP) for a chosen direction has been used. Measuring was carried out in the plane of the plates, as well as in the other two directions relating to rolling. The trigonal diagram of TP changes with degrees of deformation was built. Two stages of TP changes with deformation degrees are revealed: rate of the TP changes at the initial stage and, in part, characteristics of the subsequent stage depend on the initial texture of the materials. The second stage is characterized either by achievement of a minimum of TP in the rolling direction of the plates, or by moderate and even slight changes of them. In an example of hafnium, it has established that the increased rate of initial changes in TP is exclusively associated with intensive twinning predominantly by the {10‾12}  system. Arguments for dominance of twinning in the texture formation in hafnium and zirconium on the subsequent stage of rolling deformation are give
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