Killing in Pairs: Radicalisation Patterns of Violent Dyads

In recent years there has been an upsurge in violent attacks conducted by pairs of individuals who have undergone a shared process of radicalisation. Violent dyads remain a relatively understudied phenomenon. Using a relational approach, this article analyses the unique character of dyadic radicalisation and how it differs from instances of lone actor or group-based terrorism. It draws on a number of recent case studies, analysing instances of non-kin, fraternal, and spousal dyads. Its principal case study is a failed attack in Germany in 2006, based on a range of documentary sources as well as an interview with one of the perpetrators

Ingenieure, Dschihad und die Rückkehr der terroristischen Persönlichkeit: Diego Gambetta und Steffen Hertog über den Zusammenhang von Ausbildung und Extremismus

Diego Gambetta / Steffen Hertog: Engineers of Jihad: The Curious Connection between Violent Extremism and Education. Princeton: Princeton University Press 2016. 978069114517

Violence, Legitimacy, and Control: The Dynamics of Rebel Rule

In this paper, we outline four key sociological processes that shape the character of rebel governance. Firstly, we review the complex relationships between rebel rule and state power and look at the ways social order is generated and maintained in the context of rebel governance. Secondly, we explore relational mechanisms of control and the capacity of rebel governance to penetrate the micro social world under its rule. Thirdly, we analyze the social mechanisms through which legitimacy is attained and maintained in a rebelocracy. Finally, we examine the organizational, ideological, and micro-interactional similarities between state- and rebel governance in order to understand how and why some forms of rebel rule transform into the established governmental structures while others fragment or collapse. We argue that in order to further develop our understanding of power relations in civil wars, we need to look at the details of concrete interactions and patterns of relationships at the local level, in which orders of violence, legitimacy and control manifest themselves in everyday life, the lived experiences of those who rule and are ruled, the practices and institutions that emerge from them, and the processes in which they are negotiated

Neoadjuvant or adjuvant therapy for resectable esophageal cancer: a clinical practice guideline

BACKGROUND: Carcinoma of the esophagus is an aggressive malignancy with an increasing incidence. Its virulence, in terms of symptoms and mortality, justifies a continued search for optimal therapy. A clinical practice guideline was developed based on a systematic review investigating neoadjuvant or adjuvant therapy on resectable thoracic esophageal cancer. METHODS: A systematic review with meta-analysis was developed and clinical recommendations were drafted. External review of the practice guideline report by practitioners in Ontario, Canada was obtained through a mailed survey, and incorporated. Final approval of the practice guideline was obtained from the Practice Guidelines Coordinating Committee. RESULTS: The systematic review was developed and recommendations were drafted, and the report was mailed to Ontario practitioners for external review. Ninety percent of respondents agreed with both the evidence summary and the draft recommendations, while only 69% approved of the draft recommendations as a practice guideline. Based on the external review, a revised document was created. The revised practice guideline was submitted to the Practice Guidelines Coordinating Committee for review. All 11 members of the PGCC returned ballots. Eight PGCC members approved the practice guideline report as written and three members approved the guideline conditional on specific concerns being addressed. After these recommended changes were made, the final practice guideline report was approved. CONCLUSION: In consideration of the systematic review, external review, and subsequent Practice Guidelines Coordinating Committee revision suggestions, and final approval, the Gastrointestinal Cancer Disease Site Group recommends the following: For adult patients with resectable thoracic esophageal cancer for whom surgery is considered appropriate, surgery alone (i.e., without neoadjuvant or adjuvant therapy) is recommended as the standard practice

Differences in Attachment, Resilience, and Negative Affect in Non-Treatment-Seeking and Treatment-Seeking EMS Professionals

Emergency medical service (EMS) professionals have a stressful vocation, inarguably worsened by the COVID-19 pandemic, which affects their mental health and makes them a vulnerable population warranting further study. However, to date, no published research has compared non-treatment and treatment-seeking EMS professionals in the same greater metropolitan area. In this study, we examined differences and similarities among the non-treatment-seeking EMS professionals (n = 57) from a local EMS agency and treatment-seeking EMS personnel (n = 53) from a non-profit community treatment center on six assessment instruments that measure attachment avoidance, attachment anxiety, resilience, depression, generalized anxiety, posttraumatic stress disorder (PTSD), and suicidality. The Mann-Whitney U test revealed attachment avoidance, attachment anxiety, depression, generalized anxiety, and posttraumatic stress disorder (PTSD) were significantly higher in the treatment-seeking sample compared to the non-treatment-seeking group. Resilience and suicide did not significantly differ. Correlational analyses revealed that the most consistent findings for both samples were PTSD, depression, and generalized anxiety. Findings suggest that negative affect may underlie these three constructs, regardless of whether the individual is treatment-seeking or not. These findings are conceptualized through three different theoretical frameworks: attachment, resilience, and negative affect. We also make recommendations for EMS agencies and suggest future scholarship based on these preliminary findings

Differences in Attachment, Resilience, and Negative Affect in Non-Treatment-Seeking and Treatment-Seeking EMS Professionals

Emergency medical service (EMS) professionals have a stressful vocation, inarguably worsened by the COVID-19 pandemic, which affects their mental health and makes them a vulnerable population warranting further study. However, to date, no published research has compared non-treatment and treatment-seeking EMS professionals in the same greater metropolitan area. In this study, we examined differences and similarities among the non-treatment-seeking EMS professionals (n = 57) from a local EMS agency and treatment-seeking EMS personnel (n = 53) from a non-profit community treatment center on six assessment instruments that measure attachment avoidance, attachment anxiety, resilience, depression, generalized anxiety, posttraumatic stress disorder (PTSD), and suicidality. The Mann-Whitney U test revealed attachment avoidance, attachment anxiety, depression, generalized anxiety, and posttraumatic stress disorder (PTSD) were significantly higher in the treatment-seeking sample compared to the non-treatment-seeking group

Cyclosporin versus Tacrolimus for Liver Transplanted Patients

A systematic review of randomized clinical trials (RCT) was undertaken to evaluate the beneficial and harmful effects of immunosuppression with cyclosporin versus tacrolimus for liver transplanted patients. MEDLINE, EMBASE, Cochrane Central and Hepato-Biliary Group Controlled Trials Registers were searched. Using fixed and random effects model, relative risk (RR), values \u3c1 favoring\u3etacrolimus, with 95% confidence intervals (CI) were calculated. Of 717 potentially relevant references, 16 RCTs were eligible for inclusion. Mortality and graft loss at 1 year were significantly reduced in tacrolimus-treated recipients (Death: RR 0.85, 95% CI 0.73-0.99; graft loss: RR 0.73, 95% CI 0.61-0.86). Tacrolimus reduced the number of recipients with acute rejection (RR 0.81, 95% CI 0.75-0.88) and steroid-resistant rejection (RR 0.54, 95% CI 0.47-0.74) in the first year. Lymphoproliferative disorder or dialysis rates were not different but more de novo diabetes (RR 1.38, 95% CI 1.01-1.86) occurred with tacrolimus. More patients stopped cyclosporin than tacrolimus (RR 0.57, 95% CI 0.49-0.66). Treating 100 recipients with tacrolimus instead of cyclosporin would avoid rejection and steroid-resistant rejection in nine and seven patients respectively, graft loss and death in five and two patients respectively, but four additional patients would develop diabetes after liver transplantation