245 research outputs found
Hahn's Symmetric Quantum Variational Calculus
We introduce and develop the Hahn symmetric quantum calculus with
applications to the calculus of variations. Namely, we obtain a necessary
optimality condition of Euler-Lagrange type and a sufficient optimality
condition for variational problems within the context of Hahn's symmetric
calculus. Moreover, we show the effectiveness of Leitmann's direct method when
applied to Hahn's symmetric variational calculus. Illustrative examples are
provided.Comment: This is a preprint of a paper whose final and definite form will
appear in the international journal Numerical Algebra, Control and
Optimization (NACO). Paper accepted for publication 06-Sept-201
On finite -groups whose automorphisms are all central
An automorphism of a group is said to be central if
commutes with every inner automorphism of . We construct a family of
non-special finite -groups having abelian automorphism groups. These groups
provide counter examples to a conjecture of A. Mahalanobis [Israel J. Math.,
{\bf 165} (2008), 161 - 187]. We also construct a family of finite -groups
having non-abelian automorphism groups and all automorphisms central. This
solves a problem of I. Malinowska [Advances in group theory, Aracne Editrice,
Rome 2002, 111-127].Comment: 11 pages, Counter examples to a conjecture from [Israel J. Math.,
{\bf 165} (2008), 161 - 187]; This paper will appear in Israel J. Math. in
201
Measurement and comparison of individual external doses of high-school students living in Japan, France, Poland and Belarus -- the "D-shuttle" project --
Twelve high schools in Japan (of which six are in Fukushima Prefecture), four
in France, eight in Poland and two in Belarus cooperated in the measurement and
comparison of individual external doses in 2014. In total 216 high-school
students and teachers participated in the study. Each participant wore an
electronic personal dosimeter "D-shuttle" for two weeks, and kept a journal of
his/her whereabouts and activities. The distributions of annual external doses
estimated for each region overlap with each other, demonstrating that the
personal external individual doses in locations where residence is currently
allowed in Fukushima Prefecture and in Belarus are well within the range of
estimated annual doses due to the background radiation level of other
regions/countries
The effects of soil liming and sewage sludge application on dynamics of copper fractions and total copper concentration
On consensus in the Cucker--Smale type model on isolated time scales
This article addresses a consensus phenomenon in a Cucker-Smale model where the magnitude of the step size is not necessarily a constant but it is a function of time. In the considered model the weights of mutual influences in the group of agents do not change. A sufficient condition under which the proposed model tends to a consensus is obtained. This condition strikingly demonstrates the importance of the graininess function in a consensus phenomenon. The results are illustrated by numerical simulations.publishe
New applications of the variational iteration method - from differential equations to q-fractional difference equations
Angiomyolipoma Have Common Mutations in TSC2 but No Other Common Genetic Events
Renal angiomyolipoma are part of the PEComa family of neoplasms, and occur both in association with Tuberous Sclerosis Complex (TSC) and independent of that disorder. Previous studies on the molecular genetic alterations that occur in angiomyolipoma are very limited. We evaluated 9 angiomyolipoma for which frozen tissue was available from a consecutive surgical series. Seven of 8 samples subjected to RT-PCR-cDNA sequencing showed mutations in TSC2; none showed mutations in TSC1 or RHEB. Six of the seven mutations were deletions. We searched for 983 activating and inactivating mutations in 115 genes, and found none in these tumors. Similarly analysis for genomic regions of loss or gain, assessed by Affymetrix SNP6.0 analysis, showed no abnormalities. Loss of heterozygosity in the TSC2 region was commonly seen, except in patients with low frequency TSC2 mutations. We conclude that sporadic renal angiomyolipoma usually have mutations in TSC2, but not TSC1 or RHEB, and have no other common genomic events, among those we searched for. However, chromosomal translocations and gene fusion events were not assessed here. TSC2 inactivation by mutation is a consistent and likely necessary genetic event in the pathogenesis of most angiomyolipoma
Targeted Deletion of Kcne2 Causes Gastritis Cystica Profunda and Gastric Neoplasia
Gastric cancer is the second leading cause of cancer death worldwide. Predisposing factors include achlorhydria, Helicobacter pylori infection, oxyntic atrophy and TFF2-expressing metaplasia. In parietal cells, apical potassium channels comprising the KCNQ1 α subunit and the KCNE2 ÎČ subunit provide a K+ efflux current to facilitate gastric acid secretion by the apical H+K+ATPase. Accordingly, genetic deletion of murine Kcnq1 or Kcne2 impairs gastric acid secretion. Other evidence has suggested a role for KCNE2 in human gastric cancer cell proliferation, independent of its role in gastric acidification. Here, we demonstrate that 1-year-old Kcne2â/â mice in a pathogen-free environment all exhibit a severe gastric preneoplastic phenotype comprising gastritis cystica profunda, 6-fold increased stomach mass, increased Ki67 and nuclear Cyclin D1 expression, and TFF2- and cytokeratin 7-expressing metaplasia. Some Kcne2â/âmice also exhibited pyloric polypoid adenomas extending into the duodenum, and neoplastic invasion of thin walled vessels in the sub-mucosa. Finally, analysis of human gastric cancer tissue indicated reduced parietal cell KCNE2 expression. Together with previous findings, the results suggest KCNE2 disruption as a possible risk factor for gastric neoplasia
Fractional variational problems depending on indefinite integrals and with delay
The aim of this paper is to exhibit a necessary and sufficient condition of optimality for functionals depending on fractional integrals and derivatives, on indefinite integrals and on presence of time delay. We exemplify with one example, where we nd analytically the minimizer
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