Integrated microsystems for molecular pathology

We have integrated electronic, optical, magnetic, thermal and fluidic devices into systems to construct useful analysis tools. Over the past several years, we have developed soft lithography approaches to define microfluidic systems in which pico-Liter volumes can be manipulated. These fluidic delivery systems have more recently been integrated with optical and electronic devices. We have also developed thermal control systems with fast (>50oC/s) cooling and heating ramp speeds and excellent accuracy

Spatio-temporal analysis of urban dynamics in Kashmir valley (1901-2011) using geographical information system

Kashmir valley is the most urbanized region of Indian Himalayan region. The study of distribution, growth and extent of its urban centers is vital to create a sound economic base as urban centers are reflectors of overall development of a region. The present study has been carried out using geographical information system to analyze the spatial distribution of different size class towns in different physiographic divisions of the valley. The study reveals that Srinagar is a primate city while almost all the urban centers fall in its zone of influence. The urban development in the valley is very lopsided and imbalanced with Srinagar witnessing tremendous growth and small urban centers have either recorded sluggish growth or have shown signs of stagnation. This twin process has made urban growth very complex phenomenon and a challenging task for city planners to ensure a reasonable quality of life and environment to the inhabitants. The unplanned and unregulated urbanization is leading to several kinds of environmental change which are more intensive and hazardous in the ecologically fragile Kashmir Himalayas. The present study will help in devising a balanced urban growth strategy in the region, by reducing the disparities in the levels of socio-economic development

Analysis of population growth and land use change in Anantnag town of South Kashmir using remote sensing and geographical information system

The Himalayan region is currently experiencing unplanned and unregulated urban growth. The fast expansion of road linkages, emergence and growth of rural service centers and increased access to markets has facilitated urbanization in Himalayas. The growth in human population is considered not only one of the important causes of urban expansion but also a key driving force of land use land cover (LULC) change. The present study analyses the urban growth of Anantnag town which acts as district headquarter of Anantnag district in South Kashmir Region. The response of various LULC categories to growing population of the town was analyzed using integrated technologies of remote sensing and geographic information system. The results have revealed that the town has registered an increase by 4.37 fold in population and 7.5 fold in area from 1981 to 2011. The arable land has been converted into built-up area and is devoted to various urban land uses. It is therefore highly imperative to analyze and interpret the steering factors of fast urban growth and assess its environmental impacts

Ontology-based Access Control in Open Scenarios: Applications to Social Networks and the Cloud

La integració d'Internet a la societat actual ha fet possible compartir fàcilment grans quantitats d'informació electrònica i recursos informàtics (que inclouen maquinari, serveis informàtics, etc.) en entorns distribuïts oberts. Aquests entorns serveixen de plataforma comuna per a usuaris heterogenis (per exemple, empreses, individus, etc.) on es proporciona allotjament d'aplicacions i sistemes d'usuari personalitzades; i on s'ofereix un accés als recursos compartits des de qualsevol lloc i amb menys esforços administratius. El resultat és un entorn que permet a individus i empreses augmentar significativament la seva productivitat. Com ja s'ha dit, l'intercanvi de recursos en entorns oberts proporciona importants avantatges per als diferents usuaris, però, també augmenta significativament les amenaces a la seva privacitat. Les dades electròniques compartides poden ser explotades per tercers (per exemple, entitats conegudes com "Data Brokers"). Més concretament, aquestes organitzacions poden agregar la informació compartida i inferir certes característiques personals sensibles dels usuaris, la qual cosa pot afectar la seva privacitat. Una manera de del.liar aquest problema consisteix a controlar l'accés dels usuaris als recursos potencialment sensibles. En concret, la gestió de control d'accés regula l'accés als recursos compartits d'acord amb les credencials dels usuaris, el tipus de recurs i les preferències de privacitat dels propietaris dels recursos/dades. La gestió eficient de control d'accés és crucial en entorns grans i dinàmics. D'altra banda, per tal de proposar una solució viable i escalable, cal eliminar la gestió manual de regles i restriccions (en la qual, la majoria de les solucions disponibles depenen), atès que aquesta constitueix una pesada càrrega per a usuaris i administradors . Finalment, la gestió del control d'accés ha de ser intuïtiu per als usuaris finals, que en general no tenen grans coneixements tècnics.La integración de Internet en la sociedad actual ha hecho posible compartir fácilmente grandes cantidades de información electrónica y recursos informáticos (que incluyen hardware, servicios informáticos, etc.) en entornos distribuidos abiertos. Estos entornos sirven de plataforma común para usuarios heterogéneos (por ejemplo, empresas, individuos, etc.) donde se proporciona alojamiento de aplicaciones y sistemas de usuario personalizadas; y donde se ofrece un acceso ubicuo y con menos esfuerzos administrativos a los recursos compartidos. El resultado es un entorno que permite a individuos y empresas aumentar significativamente su productividad. Como ya se ha dicho, el intercambio de recursos en entornos abiertos proporciona importantes ventajas para los distintos usuarios, no obstante, también aumenta significativamente las amenazas a su privacidad. Los datos electrónicos compartidos pueden ser explotados por terceros (por ejemplo, entidades conocidas como “Data Brokers”). Más concretamente, estas organizaciones pueden agregar la información compartida e inferir ciertas características personales sensibles de los usuarios, lo cual puede afectar a su privacidad. Una manera de paliar este problema consiste en controlar el acceso de los usuarios a los recursos potencialmente sensibles. En concreto, la gestión de control de acceso regula el acceso a los recursos compartidos de acuerdo con las credenciales de los usuarios, el tipo de recurso y las preferencias de privacidad de los propietarios de los recursos/datos. La gestión eficiente de control de acceso es crucial en entornos grandes y dinámicos. Por otra parte, con el fin de proponer una solución viable y escalable, es necesario eliminar la gestión manual de reglas y restricciones (en la cual, la mayoría de las soluciones disponibles dependen), dado que ésta constituye una pesada carga para usuarios y administradores. Por último, la gestión del control de acceso debe ser intuitivo para los usuarios finales, que por lo general carecen de grandes conocimientos técnicos.Thanks to the advent of the Internet, it is now possible to easily share vast amounts of electronic information and computer resources (which include hardware, computer services, etc.) in open distributed environments. These environments serve as a common platform for heterogeneous users (e.g., corporate, individuals etc.) by hosting customized user applications and systems, providing ubiquitous access to the shared resources and requiring less administrative efforts; as a result, they enable users and companies to increase their productivity. Unfortunately, sharing of resources in open environments has significantly increased the privacy threats to the users. Indeed, shared electronic data may be exploited by third parties, such as Data Brokers, which may aggregate, infer and redistribute (sensitive) personal features, thus potentially impairing the privacy of the individuals. A way to palliate this problem consists on controlling the access of users over the potentially sensitive resources. Specifically, access control management regulates the access to the shared resources according to the credentials of the users, the type of resource and the privacy preferences of the resource/data owners. The efficient management of access control is crucial in large and dynamic environments such as the ones described above. Moreover, in order to propose a feasible and scalable solution, we need to get rid of manual management of rules/constraints (in which most available solutions rely) that constitutes a serious burden for the users and the administrators. Finally, access control management should be intuitive for the end users, who usually lack technical expertise, and they may find access control mechanism more difficult to understand and rigid to apply due to its complex configuration settings

The Role of Emerging Digital Technologies in the Apparel Industry of Pakistan

Abstract Purpose: Current study examines the relationship of industry 4.0 on firm performance through process mediation of employee involvement and mass customization capabilities. The motivation to conduct the current study was driven by the decreasing trend of Pakistan apparel exports and the inconsistent findings in the literature on the relationship among variables. Design/Methodology/Approach: Population of the study are the export members firms of HS code 61 and HS code 62 apparel manufacturing firms. From 1564 firms 10000 senior and middle management identified as a population. Structural equation modeling (SEM) was used to test the research model. Findings: The results reveal that industry 4.0 technologies positively impacted firm performance. Study findings also show the process mediation of employee involvement and mass customization capability between big data and firm performance. Implication/Originality/Value: To the best author's knowledge, this is the first attempt to examine the process mediation of employee involvement and mass customization capability on the relationship between industry 4.0 and Pakistan apparel firm performance

Synthesis of Substituted Dibenzothiophenes, Pyrazines, Quinoxalines, Flavones, Pyrimidines and Furans by Regioselective Palladium (0)-Catalyzed Cross-Coupling Reactions

The palladium(0)-catalyzed Heck reactions of brominated benzothiophene provided functionalized dibenzothiophenes by 6π-electro cyclization reactions. Heck reactions of dichloropyrazine and quinoxaline provided dialkenyl-, 2-alkenyl-3-alkyl and dialkylpyrazines and quinoxalines. Suzuki-Miyaura reactions of the bis(triflate) of 7,8- dihyroxyflavone with arylboronic acids afforded aryl-substituted flavones with excellent site-selectivity. Sonogashira reactions of tetrachloropyrimidine and tetrabromofuran provided di-, tri-, tetra-alkynylated and mixed Sonogashira-Suzuki products with excellent fluorescence properties