DUŽINSKO-MASENI ODNOS I ODNOS DUŽINA-DUŽINA KOD ŠEST VRSTA RIBA IZ PERZIJSKOG ZALJEVA

Length–weight relationship (LWR) and length–length relationship (LLR) were estimated for six species of ponyfishes captured in the Persian Gulf, Iran. The LWRs indicated isometric growth in ornate ponyfish (Equulites lineolatus), common ponyfish (Leiognathus equulus) and deep pugnose ponyfish (Secutor ruconius) species, positive allometric growth in striped ponyfish (Aurigequula fasciata) and negative allometric growth in decorated ponyfish (Nuchequula gerreoides) and orangefin ponyfish (Photopectoralis bindus). LWR and LLR parameters for one of the species (E. lineolatus) are given for the first time. The relationships between TL, FL and SL were all linear and highly correlated (for all cases: r2 > 0.97).Dužinsko-maseni odnos (LWR) i odnos dužina-dužina (LLR) procijenjene su na šest vrsta riba ulovljenih u Perzijskom zaljevu, Iran. Dužinsko-masenim odnosom ustanovljen je izometrijski rast kod vrsta Equulites lineolatus, Leiognathus equulus i Secutor ruconius, pozitivni alometrijski rast kod Aurigequula fasciata i negativan alometrijski rast kod Nuchequula gerreoides i Photopectoralis bindus. LWR i LLR parametri vrste E. lineolatus prikazani su po prvi put. Odnosi između TL, FL i SL su linearni i visoko korelirani (za sve slučajeve: r2> 0,97)

MTHFR Gene Polymorphisms and Susceptibility to Migraine Attacks

Background and Aim:Migraine consisting of migraine with aura (MA) and migraine without aura (MO) is a painful neurovascular disorder affecting approximately 16% of the general population. A combination of genetic and environmental factors is involved in the pathogenesis of migraine. The MTHFR enzyme is involved in homocysteine (Hcy) metabolism and it has been reported that 1298 A to C and 677 C to T mutations   in the MTHFR gene are associated with an increased in plasma Hcy levels. Hcy is a highly reactive amino acid and causes endothelial injury. Because a plausible theory about vascular impairment in migraine, it is considered that mutations in MTHFR gene and folate metabolism are associated with migraine.Materials and Methods:In total, 75 patients with migraine (24 with MA and 51with MO) in accordance with the IHS criteria participated in this case-control study. Control group were 128 normal matched healthy subjecys who selected from same region without history of migraine or other neurologic disorder after interviewing and examining by a physician. Mean age at entry was 36.42±9.6 and 31.64±8.9 years old in migraine and control group respectively.  MTHFR polymorphisms were investigated by PCR-RFLP.Results:Genotypic results indicated that the prevalence of the MTHFR 677TT genotype in migraine subjects was higher than control (17.3% and 3.1% respectively, P<0.001).  Interestingly the risk of migraine was 6-fold higher in subjects possessing the MTHFR 677T homozygous variant (OR=6.5; CI95%: 2.03-20.76). No significant difference in the prevalence of MTHFR A1298C genotypes was observed in migraine group when compared to controls (P>0.001).Conclusion:It seems that MTHFR C677T is a potential genetic risk factor for migraine attacks, both in MA and MO subclasses in Iranian population. C677T and A1298C joint effect could amplify the potential influence of each SNPs.

MnCo2O4/NiCo2O4/rGO as a Catalyst Based on Binary Transition Metal Oxide for the Methanol Oxidation Reaction

The demands for alternative energy have led researchers to find effective electrocatalysts in fuel cells and increase the efficiency of existing materials. This study presents new nanocatalysts based on two binary transition metal oxides (BTMOs) and their hybrid with reduced graphene oxide for methanol oxidation. Characterization of the introduced three-component composite, including cobalt manganese oxide (MnCo2O4), nickel cobalt oxide (NiCo2O4), and reduced graphene oxide (rGO) in the form of MnCo2O4/NiCo2O4/rGO (MNR), was investigated by X-ray diffraction (XRD), scanning electron microscope (SEM), and energy-dispersive X-ray (EDX) analyses. The alcohol oxidation capability of MnCo2O4/NiCo2O4 (MN) and MNR was evaluated in the methanol oxidation reaction (MOR) process. The crucial role of rGO in improving the electrocatalytic properties of catalysts stems from its large active surface area and high electrical conductivity. The alcohol oxidation tests of MN and MNR showed an adequate ability to oxidize methanol. The better performance of MNR was due to the synergistic effect of MnCo2O4/NiCo2O4 and rGO. MN and MNR nanocatalysts, with a maximum current density of 14.58 and 24.76 mA/cm2 and overvoltage of 0.6 and 0.58 V, as well as cyclic stability of 98.3% and 99.7% (at optimal methanol concentration/scan rate of 20 mV/S), respectively, can be promising and inexpensive options in the field of efficient nanocatalysts for use in methanol fuel cell anodes

Circulating levels of novel adipocytokines in patients with colorectal cancer

Objective: Adipocytokines have been reported to contribute to the pathogenesis of colorectal cancer (CRC). The aim of this matched case-control study was to explore circulating novel adipocytokines, such as serum visfatin, omentin-1 and vaspin levels in patients with CRC. Method: Serum visfatin, omentin-1, and vaspin levels were measured in 69 subjects (39 patients with colorectal cancer and 30 age- and sex-matched healthy controls) using enzyme-linked immunosorbent assay (ELISA) methods. Results: Compared with the controls, patients with CRC had significantly higher circulating omentin-1 (203.23 vs 9.12 ng/ml, p < 0.0001) visfatin (4.03 vs 2.01 ng/ml, p < 0.0001) and vaspin (0.54 vs 0.31 ng/ ml, p = 0.015) levels. After adjustment for covariates (age and body mass index), patients with CRC had significantly higher serum omentin-1 (p < 0.0001), visfatin (p < 0.0001), and vaspin (p = 0.040) levels than the control group. Furthermore, the results did not change when age and waist-to-hip ratio were considered as covariates in the general linear models. Conclusions: The observed higher levels of omentin-1, visfatin, and vaspin in patients with CRC, independent of measures of obesity, suggest that these adipocytokines may have a potential role in the development of CRC through mechanisms other than the indirect mechanisms that are active in the association between obesity and CRC

Circulating levels of novel adipocytokines in patients with colorectal cancer

Objective: Adipocytokines have been reported to contribute to the pathogenesis of colorectal cancer (CRC). The aim of this matched case-control study was to explore circulating novel adipocytokines, such as serum visfatin, omentin-1 and vaspin levels in patients with CRC. Method: Serum visfatin, omentin-1, and vaspin levels were measured in 69 subjects (39 patients with colorectal cancer and 30 age- and sex-matched healthy controls) using enzyme-linked immunosorbent assay (ELISA) methods. Results: Compared with the controls, patients with CRC had significantly higher circulating omentin-1 (203.23 vs 9.12 ng/ml, p < 0.0001) visfatin (4.03 vs 2.01 ng/ml, p < 0.0001) and vaspin (0.54 vs 0.31 ng/ ml, p = 0.015) levels. After adjustment for covariates (age and body mass index), patients with CRC had significantly higher serum omentin-1 (p < 0.0001), visfatin (p < 0.0001), and vaspin (p = 0.040) levels than the control group. Furthermore, the results did not change when age and waist-to-hip ratio were considered as covariates in the general linear models. Conclusions: The observed higher levels of omentin-1, visfatin, and vaspin in patients with CRC, independent of measures of obesity, suggest that these adipocytokines may have a potential role in the development of CRC through mechanisms other than the indirect mechanisms that are active in the association between obesity and CRC

Internal evaluation of speech therapy department of Semnan University of Medical Sciences

Introduction: Using students' view for teacher evaluation is a common method. This study was designed to investigate the view of faculties and medical students about faculty teaching experiences. Materials and Methods: 100 medical students and 35 faculties from Jahrom University of Medical Sciences were participated in this study. Two separate questionnaires were designed for this purpose and after determining validity and reliability completed by teachers and students. Results: 70.9 percent of faculties reported that they are satisfied with evaluation by students. 48.6 percent of them reported that feedback from this evaluation improved their teaching. 48.8 percent of them thought that some students behave spitefully. 60 percent reported self assessments as a useful method for evaluation of their own teaching. The majority of medical students (76.6%) reported that teachers' communication skills are one of the important factors in teacher evaluation. 67.4 percent of them reported that they completed the teachers' evaluation forms carefully and 60.9 percent of them asserted that teachers, who take difficult examinations, have lower grades in evaluation forms. Conclusion: In general, most teachers are agreed with teacher evaluation. Since students' opinion about their teachers is influenced by some factors which have no close relationship with the evaluation subject and is merely related to other factors, using other evaluation methods such as self evaluation and peer evaluation seems to be necessary. In addition, we should establish a single national and standard method for teacher evaluation all over the country

Secondary findings from whole-exome sequencing data in families with familial combined hyperlipidemia (FCHL)

Acknowledgements The grant of this study was paid by Mashhad University of Medical Sciences, Mashhad, Iran. Funding This study was funded by Mashhad University of Medical Sciences.Peer reviewedPublisher PD

A genetic variant in CDKN2A/2B locus was associated with poor prognosis in patients with 1 esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is among the leading causes of cancer related death. Despite extensive efforts in identifying valid cancer prognostic biomarkers, only a very small number of markers have been identified. Several genetic variants in the 9p21 region have been identified that are associated with the risk of multiple cancers. Here, we explored the association of two genetic variants in the 9p21 region, CDKN2A/B, rs10811661 and rs1333049 for the first time in 273 subjects with, or without ESCC. We observed that patients with ESCC had a higher frequency of a TT genotype for rs10811661 than individuals in the control group, and this polymorphism was also associated with tumor size. Moreover, a CC genotype for the rs1333049 polymorphism was associated with a reduced OS of patients with ESCC. In particular, patients with a CC (rs1333049) genotype had a significantly shorter OS (CC genotype: 34.5±8.9 months vs. CG+GG: 47.7±5.9 months; p value= 0.03). We have also shown the association of a novel genetic variant in CDKN2B gene with clinical outcome of ESCC patients. Further investigations are warranted in a larger population to explore the value of emerging markers as a risk stratification marker in ESCC. Key word: Esophageal squamous cell carcinoma, risk marker, CDKN2A/B, polymorphis

Investigation of the effect of education on nutritional knowledge, attitude and performance of primary school students in Ilam - 2015

Background and objective: Nutritional habits are formed in childhood and will remain until the end of life. Proper nutrition in childhood leads to the promotion of growth and development of child and reduces the risk of chronic diseases during adulthood. This study aimed to assess the effect of education about nutrition on nutritional knowledge, attitude and performance of students in primary schools. Methods: This is a quasi-experimental study which is conducted in 2015. 180 students from primary school in Ilam city were selected randomly and assigned into case (90 people) and control (90 people) groups. Before initiation of educations, a pretest was held in both groups. Then for the case group, a nutritional education was performed during 5 sessions of 45 minutes. After 2 weeks of finishing the educational sessions, posttest was performed by giving a questionnaire of knowledge, attitude and performance to case and control groups. Eventually, two groups were compared with each other in terms of nutritional knowledge, attitude and performance. In order to analyze the collected data, SPSS 21 software was used. The significance level of tests was 5% and descriptive statistics including tables and numeric indices and also inferential tests including paired t-Test, independent t-Test and Chi-square were used. Results: Findings of this study showed that in the case group, there was a statistically significant difference between the mean score of knowledge, attitude and performance of students before and after education (P 0.05). There was also a significant difference between case and control groups after education (P< 0.05). Conclusion: Nutritional education may lead to the improvement of nutritional knowledge, attitude and performance of primary school students. Considering the importance and role of students and also low cost of preventive measures in comparison with therapeutic measures, it looks necessary to expand this type of educational program